| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fatemeh Yazarlou, Mobina Tabibian, Asaad Azarnezhad, Habib Sadeghi Rad, Leonard Lipovich, Golshid Sanati, Hamid Mostafavi Abdolmaleky, Fatemeh Alizade. Evaluating Gene Expression and Methylation Profiles of TCF4, MBP, and EGR1 in Peripheral Blood of Drug-Free Patients with Schizophrenia: Correlations with Psychopathology, Intelligence, and Cognitive Impairment. Journal of molecular neuroscience : MN. 2023-09-05. PMID:37668894. |
evaluating gene expression and methylation profiles of tcf4, mbp, and egr1 in peripheral blood of drug-free patients with schizophrenia: correlations with psychopathology, intelligence, and cognitive impairment. |
2023-09-05 |
2023-09-07 |
human |
| Zhijun Li, Xinwei Li, Mengdi Jin, Yang Liu, Yang He, Ningning Jia, Xingyao Cui, Yane Liu, Guoyan Hu, Qiong Y. Identification of potential biomarkers and their correlation with immune infiltration cells in schizophrenia using combinative bioinformatics strategy. Psychiatry research. vol 314. 2022-06-06. PMID:35660966. |
we identified 15 key genes (slc1a3, aqp4, gja1, aldh1l1, sox9, slc4a4, egr1, notch2, pvalb, id4, abcg2, mettl7a, arc, f3 and emx2) in schizophrenia by performing multiple bioinformatics analysis algorithms. |
2022-06-06 |
2023-08-14 |
human |
| Yuriko Iwakura, Ryoka Kawahara-Miki, Satoshi Kida, Hidekazu Sotoyama, Ramil Gabdulkhaev, Hitoshi Takahashi, Yasuto Kunii, Mizuki Hino, Atsuko Nagaoka, Ryuta Izumi, Risa Shishido, Toshiyuki Someya, Hirooki Yabe, Akiyoshi Kakita, Hiroyuki Naw. Elevation of EGR1/zif268, a Neural Activity Marker, in the Auditory Cortex of Patients with Schizophrenia and its Animal Model. Neurochemical research. 2022-04-26. PMID:35469366. |
a similar increase in egr1 levels was observed in the postmortem superior temporal cortex of patients with schizophrenia. |
2022-04-26 |
2023-08-13 |
rat |
| Yuriko Iwakura, Ryoka Kawahara-Miki, Satoshi Kida, Hidekazu Sotoyama, Ramil Gabdulkhaev, Hitoshi Takahashi, Yasuto Kunii, Mizuki Hino, Atsuko Nagaoka, Ryuta Izumi, Risa Shishido, Toshiyuki Someya, Hirooki Yabe, Akiyoshi Kakita, Hiroyuki Naw. Elevation of EGR1/zif268, a Neural Activity Marker, in the Auditory Cortex of Patients with Schizophrenia and its Animal Model. Neurochemical research. 2022-04-26. PMID:35469366. |
the commonality of the egr1 increase indicates that the egr1 elevation in the auditory cortex might be one of the molecular signatures of this animal model and schizophrenia associating with hallucination. |
2022-04-26 |
2023-08-13 |
rat |
| Mitra Etemadikhah, Adnan Niazi, Lennart Wetterberg, Lars Feu. Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes. Scientific reports. vol 10. issue 1. 2020-11-30. PMID:31959813. |
we found differential fibroblast expression between cases and controls for 48 genes, including eight genes previously implicated in schizophrenia or schizophrenia related pathways; hgf, prrt2, egr1, egr3, c11orf87, tlr3, plekhh2 and pik3cd. |
2020-11-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
gene expression analyses showed that the average egr1 mrna and protein levels in lymphoblastoid cell lines of schizophrenia in male, but not female, were significantly higher than those in controls. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
however, the gender-specific association of elevated egr1 expression might be involved in the pathophysiology of schizophrenia. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
egr1, involved in the regulation of synaptic plasticity, learning, and memory, is considered a candidate gene for schizophrenia. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
there were no statistically significant differences in dna methylation levels of 17 cpg sites at the egr1 promoter region between 64 patients with schizophrenia compared with 64 controls. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
functional analyses and effect of dna methylation on the egr1 gene in patients with schizophrenia. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
we conducted in vitro dna methylation reaction, luciferase activity assay, and pyrosequencing to assess dna methylation of egr1 expression underlying the pathophysiology of schizophrenia. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
these results suggest that the exonic mutations in egr1 and dna methylation regulating egr1 expression might not be associated with schizophrenia. |
2019-12-30 |
2023-08-13 |
Not clear |
| Tsung-Ming Hu, Shaw-Ji Chen, Shih-Hsin Hsu, Min-Chih Chen. Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia. Psychiatry research. vol 275. 2019-12-30. PMID:30952071. |
we resequenced the exonic regions of egr1 in 516 patients with schizophrenia and conducted a reporter gene assay. |
2019-12-30 |
2023-08-13 |
Not clear |