| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting Zhang, Chang Liu, Ning Zhong, Yichen Wang, Yiyun Huang, Xiaoqin Zhan. Advances in the Treatment of Cognitive Impairment in Schizophrenia: Targeting NMDA Receptor Pathways. International journal of molecular sciences. vol 25. issue 19. 2024-10-16. PMID:39408997. |
cognitive impairment in schizophrenia encompasses a wide range of domains, including processing speed, episodic memory, working memory, and executive function. |
2024-10-16 |
2024-10-18 |
Not clear |
| Christin Schifani, Colin Hawco, Zafiris J Daskalakis, Tarek K Rajji, Benoit H Mulsant, Vinh Tan, Erin W Dickie, Iska Moxon-Emre, Daniel M Blumberger, Aristotle N Voinesko. Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Reduces Variability in Brain Function in Schizophrenia: Data From a Double-Blind, Randomized, Sham-Controlled Trial. Schizophrenia bulletin. 2024-10-07. PMID:39373168. |
we perform a secondary analysis using data from a double-blind randomized controlled 4-week trial of 20 hz active versus sham rtms to dorsolateral prefrontal cortex (dlpfc) during a working memory task in participants with schizophrenia. |
2024-10-07 |
2024-10-09 |
human |
| Dominique Arion, John F Enwright, Guillermo Gonzalez-Burgos, David A Lewi. Cell Type-Specific Profiles and Developmental Trajectories of Transcriptomes in Primate Prefrontal Layer 3 Pyramidal Neurons: Implications for Schizophrenia. The American journal of psychiatry. vol 181. issue 10. 2024-10-01. PMID:39350613. |
however, how the transcriptomes of these l3pn subtypes might shift during late postnatal development when working memory impairments emerge in individuals later diagnosed with schizophrenia is not known. |
2024-10-01 |
2024-10-03 |
monkey |
| Reut Komemi, Hana Tubenbaltt, Eiran V Harel, Mor Nahum, Lena Lipskaya-Velikovsk. Ecological virtual reality-based cognitive remediation among inpatients with schizophrenia: A pilot study. Schizophrenia research. Cognition. vol 38. 2024-09-16. PMID:39281321. |
twenty-three inpatients with schizophrenia (male: 33.3 ± 8.5; 4 female) completed 8, 20-min cr-evr sessions, with exercises training the cognitive abilities of inhibition, planning, working memory, shifting, self-initiation, persistence, and attention. |
2024-09-16 |
2024-09-19 |
human |
| Maltesh Kambali, Yan Li, Petr Unichenko, Jessica A Feria Pliego, Rachita Yadav, Jing Liu, Patrick McGuinness, Johanna G Cobb, Muxiao Wang, Rajasekar Nagarajan, Jinrui Lyu, Vanessa Vongsouthi, Colin J Jackson, Elif Engin, Joseph T Coyle, Jaeweon Shin, Nathaniel W Hodgson, Takao K Hensch, Michael E Talkowski, Gregg E Homanics, Vadim Y Bolshakov, Christian Henneberger, Uwe Rudolp. An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function. Molecular psychiatry. 2024-08-30. PMID:39210012. |
using a chromosome-engineered allelic series in mice, we report that a triplication of the gene encoding the glycine-catabolizing enzyme glycine decarboxylase (gldc) - as found on a small supernumerary marker chromosome in patients with psychosis - reduces extracellular glycine levels as determined by optical fluorescence resonance energy transfer (fret) in dentate gyrus (dg) and suppresses long-term potentiation (ltp) in mpp-dg synapses but not in ca3-ca1 synapses, reduces the activity of biochemical pathways implicated in schizophrenia and mitochondrial bioenergetics, and displays deficits in schizophrenia-like behaviors which are in part known to be dependent on the activity of the dentate gyrus, e.g., prepulse inhibition, startle habituation, latent inhibition, working memory, sociability and social preference. |
2024-08-30 |
2024-09-04 |
mouse |
| Wenpeng Hou, Xiangqin Qin, Hang Li, Qi Wang, Yushen Ding, Xiongying Chen, Ru Wang, Fang Dong, Qijing Bo, Xianbin Li, Fuchun Zhou, Chuanyue Wan. Interaction between BDNF Val66Met polymorphism and mismatch negativity for working memory capacity in schizophrenia. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-08-22. PMID:39174571. |
both the brain-derived neurotrophic factor (bdnf) valine (val)/methionine (met) polymorphism and mismatch negativity (mmn) amplitude are reportedly linked to working memory impairments in schizophrenia. |
2024-08-22 |
2024-08-25 |
Not clear |
| Wenpeng Hou, Xiangqin Qin, Hang Li, Qi Wang, Yushen Ding, Xiongying Chen, Ru Wang, Fang Dong, Qijing Bo, Xianbin Li, Fuchun Zhou, Chuanyue Wan. Interaction between BDNF Val66Met polymorphism and mismatch negativity for working memory capacity in schizophrenia. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-08-22. PMID:39174571. |
the trial assessed the efficacy of transcranial direct current stimulation for enhancing working memory in clinically stable schizophrenia patients, who were randomly divided into three groups: dorsolateral prefrontal cortex stimulation, posterior parietal cortex stimulation, and sham stimulation groups. |
2024-08-22 |
2024-08-25 |
Not clear |
| Wenpeng Hou, Xiangqin Qin, Hang Li, Qi Wang, Yushen Ding, Xiongying Chen, Ru Wang, Fang Dong, Qijing Bo, Xianbin Li, Fuchun Zhou, Chuanyue Wan. Interaction between BDNF Val66Met polymorphism and mismatch negativity for working memory capacity in schizophrenia. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-08-22. PMID:39174571. |
as mmn has been considered a biomarker of n-methyl-d-aspartate receptor (nmdar) function, these data shed light on the complex interactions between bdnf and nmdar in terms of working memory in schizophrenia. |
2024-08-22 |
2024-08-25 |
Not clear |
| Selvameenatchi R, Ramya Rachel Jetty, Aruna Kaki, Suresh Kumar Gunapalli, Prasanna Kumar N, Arul Saravanan . Assessment of Cognitive Functions Among Remitted Patients of Schizophrenia and Bipolar Disorder: A Comparative Study. Cureus. vol 16. issue 7. 2024-08-12. PMID:39131022. |
schizophrenia patients showed poorer attention, working memory, and visual attention/task-switching compared to bipolar patients. |
2024-08-12 |
2024-08-14 |
Not clear |
| Elise Leroux, Laura Masson, Maxime Tréhout, Sonia Dollfu. Effects of Adapted Physical Activity on White Matter Integrity in Patients with Schizophrenia. Brain sciences. vol 14. issue 7. 2024-07-27. PMID:39061450. |
schizophrenia is associated with changes in white matter (wm) integrity and with reduced life expectancy, in part because of the cardiometabolic side effects of antipsychotics. |
2024-07-27 |
2024-07-29 |
human |
| Elise Leroux, Laura Masson, Maxime Tréhout, Sonia Dollfu. Effects of Adapted Physical Activity on White Matter Integrity in Patients with Schizophrenia. Brain sciences. vol 14. issue 7. 2024-07-27. PMID:39061450. |
the study aimed to assess how an adapted pa program delivered remotely by web (e-apa) improved wm integrity in patients with schizophrenia (szps) and healthy controls (hcs) and to evaluate associations among wm integrity, cardiorespiratory fitness, and symptom severity. |
2024-07-27 |
2024-07-29 |
human |
| Daniel Núñez, Javiera Rodríguez-Delgado, Ramón D Castillo, José Yupanqui, Heidi Kloo. Effect of prior beliefs and cognitive deficits on learning in first-episode schizophrenia patients. Schizophrenia research. Cognition. vol 38. 2024-07-16. PMID:39005726. |
this study investigates the role of beliefs and cognitive variables (cvs) like working memory, associative learning, and processing speed on learning processes in individuals with schizophrenia. |
2024-07-16 |
2024-07-18 |
Not clear |
| Haluk Umit Yesilkaya, Xi Chen, Lauren Watford, Emma McCoy, Ilgin Genc, Fei Du, Dost Ongur, Cagri Yukse. Poor Self-Reported Sleep is Associated with Prolonged White Matter T2 Relaxation in Psychotic Disorders. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005452. |
schizophrenia (sz) and bipolar disorder (bd) are characterized by white matter (wm) abnormalities, however, their relationship with illness presentation is not clear. |
2024-07-15 |
2024-07-18 |
Not clear |
| Xiawei Liu, Zhening Liu, Feiwen Wang, Peng Cheng, Jun Yang, Wenjian Tan, Yixin Cheng, Danqing Huang, Zhibiao Xiang, Jiamei Zhang, Jinyue Li, Yuxin Xie, Maoxing Zhong, Jie Yan. A connectome-based model of delusion in schizophrenia using functional connectivity under working memory task. Journal of psychiatric research. vol 177. 2024-07-09. PMID:38981411. |
two hundred and thirty patients with schizophrenia (dataset 1: n = 130; dataset 2: n = 100) were enrolled and scanned for an n-back wm task. |
2024-07-09 |
2024-07-12 |
Not clear |
| Xiawei Liu, Zhening Liu, Feiwen Wang, Peng Cheng, Jun Yang, Wenjian Tan, Yixin Cheng, Danqing Huang, Zhibiao Xiang, Jiamei Zhang, Jinyue Li, Yuxin Xie, Maoxing Zhong, Jie Yan. A connectome-based model of delusion in schizophrenia using functional connectivity under working memory task. Journal of psychiatric research. vol 177. 2024-07-09. PMID:38981411. |
a connectome-based model of delusion in schizophrenia using functional connectivity under working memory task. |
2024-07-09 |
2024-07-12 |
Not clear |
| Xiawei Liu, Zhening Liu, Feiwen Wang, Peng Cheng, Jun Yang, Wenjian Tan, Yixin Cheng, Danqing Huang, Zhibiao Xiang, Jiamei Zhang, Jinyue Li, Yuxin Xie, Maoxing Zhong, Jie Yan. A connectome-based model of delusion in schizophrenia using functional connectivity under working memory task. Journal of psychiatric research. vol 177. 2024-07-09. PMID:38981411. |
however, the knowledge of neural mechanisms underlying the relationship between wm and delusion in schizophrenia is poorly investigated. |
2024-07-09 |
2024-07-12 |
Not clear |
| Qiuping Ding, Lingyu Li, Qiqi Tong, Hongjian He, Bin Gao, Ling Xi. White matter microstructure alterations of the posterior limb of internal capsule in first-episode drug naive schizophrenia patients. Brain research. 2024-07-08. PMID:38977237. |
previous studies have shown that microstructural alterations in white matter (wm) could contribute to the symptom manifestation and support the dysconnectivity hypothesis in schizophrenia patients. |
2024-07-08 |
2024-07-12 |
Not clear |
| Wenpeng Hou, Fuchun Zhou, Qi Wang, Hang Li, Xiangqin Qin, Yushen Ding, Fang Dong, Qijing Bo, Anning Li, Liang Zhang, Zhenzhu Chen, Zhimin Wang, Xianbin Li, Jimmy Lee, Chuanyue Wan. Effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial. Translational psychiatry. vol 14. issue 1. 2024-07-08. PMID:38977683. |
effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial. |
2024-07-08 |
2024-07-12 |
Not clear |
| Wenpeng Hou, Fuchun Zhou, Qi Wang, Hang Li, Xiangqin Qin, Yushen Ding, Fang Dong, Qijing Bo, Anning Li, Liang Zhang, Zhenzhu Chen, Zhimin Wang, Xianbin Li, Jimmy Lee, Chuanyue Wan. Effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial. Translational psychiatry. vol 14. issue 1. 2024-07-08. PMID:38977683. |
we evaluated the differential efficacy and underlying neuromechanisms of targeting transcranial direct current stimulation (tdcs) at the dlpfc and the ppc with concurrent cognitive performance for working memory in schizophrenia. |
2024-07-08 |
2024-07-12 |
Not clear |
| Yuhao Yao, Shufang Zhang, Boyao Wang, Xiaoyong Lin, Gaofeng Zhao, Hong Deng, Ying Che. Neural dysfunction underlying working memory processing at different stages of the illness course in schizophrenia: a comparative meta-analysis. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 7. 2024-07-03. PMID:38960703. |
neural dysfunction underlying working memory processing at different stages of the illness course in schizophrenia: a comparative meta-analysis. |
2024-07-03 |
2024-07-10 |
Not clear |