Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yunyi Zou, Xiangbin Tang, Siyuan Yang, Zhanglin Chen, Bin Liu, Zuoqiong Zhou, Xiyang Peng, Changfa Tan. New insights into the function of the NLRP3 inflammasome in sarcopenia: mechanism and therapeutic strategies. Metabolism: clinical and experimental. 2024-07-07. PMID:38972476. |
the involvement of inflammasomes in sarcopenia is widely recognized, with particular emphasis on the nlrp3 (nlr family pyrin domain containing 3) inflammasome. |
2024-07-07 |
2024-07-11 |
Not clear |
Yunyi Zou, Xiangbin Tang, Siyuan Yang, Zhanglin Chen, Bin Liu, Zuoqiong Zhou, Xiyang Peng, Changfa Tan. New insights into the function of the NLRP3 inflammasome in sarcopenia: mechanism and therapeutic strategies. Metabolism: clinical and experimental. 2024-07-07. PMID:38972476. |
furthermore, we highlight interventions targeting the nlrp3 inflammasome in the context of sarcopenia and discuss the current limitations of our knowledge in this area. |
2024-07-07 |
2024-07-11 |
Not clear |
Yunyi Zou, Xiangbin Tang, Siyuan Yang, Zhanglin Chen, Bin Liu, Zuoqiong Zhou, Xiyang Peng, Changfa Tan. New insights into the function of the NLRP3 inflammasome in sarcopenia: mechanism and therapeutic strategies. Metabolism: clinical and experimental. 2024-07-07. PMID:38972476. |
new insights into the function of the nlrp3 inflammasome in sarcopenia: mechanism and therapeutic strategies. |
2024-07-07 |
2024-07-11 |
Not clear |
Yunyi Zou, Xiangbin Tang, Siyuan Yang, Zhanglin Chen, Bin Liu, Zuoqiong Zhou, Xiyang Peng, Changfa Tan. New insights into the function of the NLRP3 inflammasome in sarcopenia: mechanism and therapeutic strategies. Metabolism: clinical and experimental. 2024-07-07. PMID:38972476. |
in this review, we aim to elucidate the underlying mechanisms of the nlrp3 inflammasome and its relevance in sarcopenia of various etiologies. |
2024-07-07 |
2024-07-11 |
Not clear |
Kaizhi Ding, Yanchun Gong, Xiaonuo Li, Yuanjie Zhu, Lihua Ya. [Role of NLRP3 inflammasomes in musculoskeletal disorders]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 40. issue 2. 2024-02-19. PMID:38369825. |
this review provides a summary of the activation pathway and mechanism of nlrp3 inflammasomes, and analyzes the role in musculoskeletal disorders such as sarcopenia, osteoporosis and arthritis, with the aim to facilitate the treatment of musculoskeletal disorders. |
2024-02-19 |
2024-02-21 |
Not clear |
Eduardo Antuña, Yaiza Potes, Francisco Javier Baena-Huerta, Cristina Cachán-Vega, Nerea Menéndez-Coto, Eva Álvarez Darriba, Marta Fernández-Fernández, Natalie Burgos Bencosme, Manuel Bermúdez, Eva María López Álvarez, José Gutiérrez-Rodríguez, José Antonio Boga, Beatriz Caballero, Ignacio Vega-Naredo, Ana Coto-Montes, Claudia Garcia-Gonzale. NLRP3 Contributes to Sarcopenia Associated to Dependency Recapitulating Inflammatory-Associated Muscle Degeneration. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338718. |
nlrp3 contributes to sarcopenia associated to dependency recapitulating inflammatory-associated muscle degeneration. |
2024-02-10 |
2024-02-12 |
Not clear |
Manfeng Wang, Meiling Liu, Wanzhen Xu, Zongyan Teng, Xiaowei Wu, Lu Gan, Yina Zhan. Sulforaphane reduces lipopolysaccharide-induced inflammation and enhances myogenic differentiation of mouse embryonic myoblasts via the toll-like receptor 4 and NLRP3 pathways. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2022-11-18. PMID:36398371. |
toll-like receptor 4 (tlr4) signaling and the nlrp3 inflammasome are involved in the inflammatory storm and the development of sarcopenia during sepsis. |
2022-11-18 |
2023-08-14 |
mouse |
Davide De Biase, Giuseppe Piegari, Francesco Prisco, Ilaria Cimmino, Ilaria d'Aquino, Valeria Baldassarre, Francesco Oriente, Serenella Papparella, Orlando Paciell. Implication of the NLRP3 Inflammasome in Bovine Age-Related Sarcopenia. International journal of molecular sciences. vol 22. issue 7. 2021-05-14. PMID:33808510. |
our results revealed the presence of morphologic sarcopenia hallmark, chronic lymphocytic inflammation and a type ii fibers-selective nlrp3 expression associated to a significant decreased number of immunolabeled-fibers in aged animals. |
2021-05-14 |
2023-08-13 |
cattle |
Davide De Biase, Giuseppe Piegari, Francesco Prisco, Ilaria Cimmino, Ilaria d'Aquino, Valeria Baldassarre, Francesco Oriente, Serenella Papparella, Orlando Paciell. Implication of the NLRP3 Inflammasome in Bovine Age-Related Sarcopenia. International journal of molecular sciences. vol 22. issue 7. 2021-05-14. PMID:33808510. |
implication of the nlrp3 inflammasome in bovine age-related sarcopenia. |
2021-05-14 |
2023-08-13 |
cattle |
Davide De Biase, Giuseppe Piegari, Francesco Prisco, Ilaria Cimmino, Ilaria d'Aquino, Valeria Baldassarre, Francesco Oriente, Serenella Papparella, Orlando Paciell. Implication of the NLRP3 Inflammasome in Bovine Age-Related Sarcopenia. International journal of molecular sciences. vol 22. issue 7. 2021-05-14. PMID:33808510. |
the aim of this work was to evaluate, for the first time, the expression of nlrp3 inflammasome in bovine skeletal muscle in order to investigate the hypothesis that inflammasome activation may trigger and sustain a pro-inflammatory environment leading to sarcopenia. |
2021-05-14 |
2023-08-13 |
cattle |
Ramy K A Sayed, Marisol Fernández-Ortiz, María E Diaz-Casado, Paula Aranda-Martínez, José Fernández-Martínez, Ana Guerra-Librero, Germaine Escames, Luis C López, Reem M Alsaadawy, Darío Acuña-Castroviej. Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 74. issue 11. 2020-06-18. PMID:30869745. |
to investigate the role of nlrp3 inflammasome in muscular aging, we evaluated here the morphological and functional markers of sarcopenia in the nlrp3-knockout mice, as well as the beneficial effect of melatonin supplementation. |
2020-06-18 |
2023-08-13 |
mouse |
Ramy K A Sayed, Marisol Fernández-Ortiz, María E Diaz-Casado, Paula Aranda-Martínez, José Fernández-Martínez, Ana Guerra-Librero, Germaine Escames, Luis C López, Reem M Alsaadawy, Darío Acuña-Castroviej. Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 74. issue 11. 2020-06-18. PMID:30869745. |
lack of nlrp3 inflammasome activation reduces age-dependent sarcopenia and mitochondrial dysfunction, favoring the prophylactic effect of melatonin. |
2020-06-18 |
2023-08-13 |
mouse |
Ramy K A Sayed, Marisol Fernández-Ortiz, María E Diaz-Casado, Paula Aranda-Martínez, José Fernández-Martínez, Ana Guerra-Librero, Germaine Escames, Luis C López, Reem M Alsaadawy, Darío Acuña-Castroviej. Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 74. issue 11. 2020-06-18. PMID:30869745. |
the fewer sarcopenic changes as well as the highly detectable prophylactic effects of melatonin treatment reported here in the muscle of nlrp3-knockout mice comparing with that previously detected in wild-type mice, confirming nlrp3 inflammasome implication in muscular aging and sarcopenia onset and progression. |
2020-06-18 |
2023-08-13 |
mouse |
Marin Jane McBride, Kevin P Foley, Donna M D'Souza, Yujin E Li, Trevor C Lau, Thomas J Hawke, Jonathan D Schertze. The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. American journal of physiology. Endocrinology and metabolism. vol 313. issue 2. 2017-09-07. PMID:28536183. |
we hypothesized that the caspase-1-containing nlrp3 inflammasome contributes to sarcopenia in mice. |
2017-09-07 |
2023-08-13 |
mouse |
Marin Jane McBride, Kevin P Foley, Donna M D'Souza, Yujin E Li, Trevor C Lau, Thomas J Hawke, Jonathan D Schertze. The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. American journal of physiology. Endocrinology and metabolism. vol 313. issue 2. 2017-09-07. PMID:28536183. |
the nlrp3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. |
2017-09-07 |
2023-08-13 |
mouse |