All Relations between Paralysis and cerebral cortex

Publication Sentence Publish Date Extraction Date Species
Kevin Lee, Victor Barradas, Nicolas Schweighofe. Self-organizing recruitment of compensatory areas maximizes residual motor performance post-stroke. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005333. the premotor cortex acted as a reserve area for fine motor control recovery, while the contra-lesional cortex helped avoid paralysis at the cost of poor joint control. 2024-07-15 2024-07-18 Not clear
Venkataramanan Srinivasan, Victoria Homer, Darren Barton, Abigail Clutterbuck-James, Siân Jenkins, Claire Potter, Kristian Brock, Ann Logan, Donna Smith, Lars Bruce, Zsuzsanna Nagy, Simon P Bac. A low molecular weight dextran sulphate, ILB®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial. PloS one. vol 19. issue 7. 2024-07-11. PMID:38990927. it is a fatal disease with specific loss of motor neurons in the spinal cord, brain stem, and motor cortex leading to progressive paralysis and usually death within five years of diagnosis. 2024-07-11 2024-07-14 Not clear
Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. 2024-07-04 2024-07-10 mouse
Alexander B Silva, Jessie R Liu, Sean L Metzger, Ilina Bhaya-Grossman, Maximilian E Dougherty, Margaret P Seaton, Kaylo T Littlejohn, Adelyn Tu-Chan, Karunesh Ganguly, David A Moses, Edward F Chan. A bilingual speech neuroprosthesis driven by cortical articulatory representations shared between languages. Nature biomedical engineering. 2024-05-22. PMID:38769157. here, we leveraged electrocorticography, along with deep-learning and statistical natural-language models of english and spanish, to record and decode activity from speech-motor cortex of a spanish-english bilingual with vocal-tract and limb paralysis into sentences in either language. 2024-05-22 2024-05-27 human
Anjing Zhang, Ying Xing, Jiayuan Zheng, Congqin Li, Yan Hua, Jian Hu, Zhanzhuang Tian, Yulong Ba. Constraint-Induced Movement Therapy Modulates Neuron Recruitment and Neurotransmission Homeostasis of the Contralesional Cortex to Enhance Function Recovery after Ischemic Stroke. ACS omega. vol 9. issue 19. 2024-05-21. PMID:38764659. this study explores how cimt may alleviate forelimb paralysis in ischemic mice, potentially through structural and functional remodeling of brain regions beyond the infarct area, especially the contralateral cortex. 2024-05-21 2024-05-27 mouse
Denis Babici, Ali A Mohamed, Olivia Mattner, Francis Demiraj, Thomas Hammon. Acute Caudate Nucleus Stroke Presenting As Hemiballismus. Cureus. vol 15. issue 11. 2023-12-05. PMID:38050508. for example, infarctions of the motor cortex present with hemiplegia or paralysis of one side of the body. 2023-12-05 2023-12-10 Not clear
Nishal P Shah, Matthew S Willsey, Nick Hahn, Foram Kamdar, Donald T Avansino, Leigh R Hochberg, Krishna V Shenoy, Jaimie M Henderso. A brain-computer typing interface using finger movements. International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering. vol 2023. 2023-07-19. PMID:37465143. intracortical brain computer interfaces (ibcis) decode neural activity from the cortex and enable motor and communication prostheses, such as cursor control, handwriting and speech, for people with paralysis. 2023-07-19 2023-08-14 human
Francis R Willett, Erin Kunz, Chaofei Fan, Donald Avansino, Guy Wilson, Eun Young Choi, Foram Kamdar, Leigh R H Hochberg, Shaul Druckmann, Krishna Shenoy, Jaimie Henderso. A high-performance speech neuroprosthesis. bioRxiv : the preprint server for biology. 2023-04-28. PMID:36711591. finally, we highlight two aspects of the neural code for speech that are encouraging for speech bcis: spatially intermixed tuning to speech articulators that makes accurate decoding possible from only a small region of cortex, and a detailed articulatory representation of phonemes that persists years after paralysis. 2023-04-28 2023-08-16 human
Francesca De Lorenzo, Patrick Lüningschrör, Jinhan Nam, Liam Beckett, Federica Pilotto, Emilia Galli, Päivi Lindholm, Cora Rüdt von Collenberg, Simon Tii Mungwa, Sibylle Jablonka, Julia Kauder, Nadine Thau-Habermann, Susanne Petri, Dan Lindholm, Smita Saxena, Michael Sendtner, Mart Saarma, Merja H Voutilaine. CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress. Brain : a journal of neurology. 2023-03-17. PMID:36928391. amyotrophic lateral sclerosis is a progressive neurodegenerative disease that affects motor neurons (mns) in the spinal cord, brainstem, and motor cortex, leading to paralysis and eventually to death within 3 to 5 years of symptom onset. 2023-03-17 2023-08-14 mouse
Kenmei Mizutani, Shigeru Sonoda, Hideaki Wakita, Yu Takahash. Effects of exercise and bryostatin-1 on functional recovery and posttranslational modification in the perilesional cortex after cerebral infarction. Neuroreport. vol 34. issue 5. 2023-03-07. PMID:36881749. neuroplasticity in the peri-infarcted cerebral cortex induced by exercise training may contribute to recovery of paralysis after cerebral infarction. 2023-03-07 2023-08-14 rat
Matrone Carmel. The paradigm of amyloid precursor protein in amyotrophic lateral sclerosis: The potential role of the Computational and structural biotechnology journal. vol 21. 2023-01-26. PMID:36698966. it is clinically characterized by the selective and progressive loss of motor neurons in the motor cortex, brain stem, and spinal cord, ultimately leading to muscle atrophy and rapidly progressive paralysis. 2023-01-26 2023-08-14 Not clear
b' Bel\\xc3\\xa9n Proa\\xc3\\xb1o, Julia Casani-Cubel, Mar\\xc3\\xada Benlloch, Ana Rodriguez-Mateos, Esther Navarro-Illana, Jose Mar\\xc3\\xada Lajara-Romance, Jose Enrique de la Rubia Ort\\xc3\\xa. Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis? Biomedicines. vol 10. issue 9. 2022-09-23. PMID:36140184.' amyotrophic lateral sclerosis (als) is a neurodegenerative disease that is characterized by the loss of upper and lower motor neurons (mns) in the cerebral cortex, brainstem and spinal cord, with consequent weakness, atrophy and the progressive paralysis of all muscles. 2022-09-23 2023-08-14 Not clear
Christoph Schweingruber, Eva Hedlun. The Cell Autonomous and Non-Cell Autonomous Aspects of Neuronal Vulnerability and Resilience in Amyotrophic Lateral Sclerosis. Biology. vol 11. issue 8. 2022-08-26. PMID:36009818. amyotrophic lateral sclerosis (als) is defined by the loss of upper motor neurons (mns) that project from the cerebral cortex to the brain stem and spinal cord and of lower mns in the brain stem and spinal cord which innervate skeletal muscles, leading to spasticity, muscle atrophy, and paralysis. 2022-08-26 2023-08-14 Not clear
Morgan E Urdaneta, Nicolas G Kunigk, Seth Currlin, Francisco Delgado, Shelley I Fried, Kevin J Ott. The Long-Term Stability of Intracortical Microstimulation and the Foreign Body Response Are Layer Dependent. Frontiers in neuroscience. vol 16. 2022-06-30. PMID:35769707. intracortical microstimulation (icms) of the somatosensory cortex (s1) can restore sensory function in patients with paralysis. 2022-06-30 2023-08-14 rat
Hiroyasu Inoue, Masahiro Oomura, Yusuke Nishikawa, Mitsuhito Mase, Noriyuki Matsukaw. New Cortical Spot Cerebral Infarction Out of Border Zone in ICA Occlusion Suggests Recanalization: A Case Report. NMC case report journal. vol 9. 2022-05-02. PMID:35493536. four days after hospitalization, the right paralysis worsened and a new cerebral infarction was observed in the cortex, outside the border zone. 2022-05-02 2023-08-13 Not clear
Matthias Hartmann, Caroline J Falconer, Alain Kaelin-Lang, René M Müri, Fred W Mas. Imagined paralysis reduces motor cortex excitability. Psychophysiology. 2022-04-08. PMID:35393640. imagined paralysis reduces motor cortex excitability. 2022-04-08 2023-08-13 human
Takuma Kato, Atsushi Yamamoto, Keisuke Imai, Kanako Menjo, Tetsuya Ioku, Daiki Takewak. [Anti-myelin oligodendrocyte glycoprotein antibody-positive unilateral cerebral cortical encephalitis occurring first as general convulsion after meningitis symptoms and second after headache]. Rinsho shinkeigaku = Clinical neurology. 2022-03-01. PMID:35228465. he was tentatively diagnosed with meningoencephalitis and todd paralysis based on elevation of cell counts in cerebrospinal fluid and abnormal high signals in the right cerebral cortex on brain flair-mri, and admitted on the same day. 2022-03-01 2023-08-13 Not clear
Rita F Marques, Kent E Dunca. SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology. Neural regeneration research. vol 17. issue 2. 2021-10-22. PMID:34269186. its defining feature is progressive loss of motor neuron function in the cortex, brainstem, and spinal cord, leading to paralysis and death. 2021-10-22 2023-08-13 mouse
L McAlary, J J Yerbury, N R Cashma. The prion-like nature of amyotrophic lateral sclerosis. Progress in molecular biology and translational science. vol 175. 2021-07-01. PMID:32958236. als is characterized by the rapid and progressive degenerations of motor neurons in the spinal cord and motor cortex, resulting in paralysis of those who suffer from it. 2021-07-01 2023-08-13 Not clear
A M Thomas, S Li, C Chu, I Shats, J Xu, P A Calabresi, P C M van Zijl, P Walczak, J W M Bult. Evaluation of cell transplant-mediated attenuation of diffuse injury in experimental autoimmune encephalomyelitis using onVDMP CEST MRI. Experimental neurology. vol 329. 2020-12-24. PMID:32304749. allogeneic grps transplanted in the motor cortex or lateral ventricles attenuated paralysis in eae mice and attenuated differences compared to naïve mice in onvdmp cest signal 5 days after transplantation near the transplantation site. 2020-12-24 2023-08-13 mouse