| Marie des Neiges Santin, Nicolas Tempier, Hayat Belaid, Matthieu Zenoni, Sylvie Dumas, \\xc3\\x85sa Wall\\xc3\\xa9n-Mackenzie, Eric Bardinet, Christophe Destrieux, Chantal Fran\\xc3\\xa7ois, Carine Karach. Anatomical characterisation of three different psychosurgical targets in the subthalamic area: from the basal ganglia to the limbic system. Brain structure & function. 2023-09-05. PMID:37668733. |
this is especially true for the medial subthalamic region (msr) which contains three targets: the anteromedial stn for obsessive compulsive disorder (ocd), the medial forebrain bundle (mfb) for depression and ocd, and the "sano triangle" for pathological aggressiveness. |
2023-09-05 |
2023-09-07 |
human |
| M Cano, P Alonso, I Mart\\xc3\\xadnez-Zalaca\\xc3\\xadn, M Subir\\xc3\\xa0, E Real, C Segal\\xc3\\xa0s, J Pujol, N Cardoner, J M Mench\\xc3\\xb3n, C Soriano-Ma. Altered functional connectivity of the subthalamus and the bed nucleus of the stria terminalis in obsessive-compulsive disorder. Psychological medicine. vol 48. issue 6. 2019-02-04. PMID:28826410. |
altered functional connectivity of the subthalamus and the bed nucleus of the stria terminalis in obsessive-compulsive disorder. |
2019-02-04 |
2023-08-13 |
Not clear |
| Hansen Lui, Jiasheng Zhang, Stefanie R Makinson, Michelle K Cahill, Kevin W Kelley, Hsin-Yi Huang, Yulei Shang, Michael C Oldham, Lauren Herl Martens, Fuying Gao, Giovanni Coppola, Steven A Sloan, Christine L Hsieh, Charles C Kim, Eileen H Bigio, Sandra Weintraub, Marek-Marsel Mesulam, Rosa Rademakers, Ian R Mackenzie, William W Seeley, Anna Karydas, Bruce L Miller, Barbara Borroni, Roberta Ghidoni, Robert V Farese, Jeanne T Paz, Ben A Barres, Eric J Huan. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell. vol 165. issue 4. 2017-01-10. PMID:27114033. |
during aging, grn(-/-) mice show profound microglia infiltration and preferential elimination of inhibitory synapses in the ventral thalamus, which lead to hyperexcitability in the thalamocortical circuits and obsessive-compulsive disorder (ocd)-like grooming behaviors. |
2017-01-10 |
2023-08-13 |
mouse |