| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Fu, Jin Bi, Yaping Yan, Xiaobo Sun, Ke Li, So Yeon Kim, Sang-Min Han, Luyao Zhou, Rui Li, Qiao Huang, Ning Wang, Aiyu Lin, Ho Jin Kim, Wei Qi. Rapid Immunodot AQP4 Assay for Neuromyelitis Optica Spectrum Disorder. JAMA neurology. 2023-09-05. PMID:37669037. |
rapid immunodot aqp4 assay for neuromyelitis optica spectrum disorder. |
2023-09-05 |
2023-09-07 |
Not clear |
| Maria Pechlivanidou, Konstantina Xenou, Dimitrios Tzanetakos, Emmanuel Koutsos, Christos Stergiou, Elisabeth Andreadou, Konstantinos Voumvourakis, Sotirios Giannopoulos, Constantinos Kilidireas, Erdem T\\xc3\\xbcz\\xc3\\xbcn, Georgios Tsivgoulis, Socrates Tzartos, John Tzarto. Potential Role of Antibodies against Aquaporin-1 in Patients with Central Nervous System Demyelination. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37629163. |
the best-known example of autoimmunity against aqps concerns the antibodies to aqp4 which are involved in the pathogenesis of neuromyelitis optica spectrum disorder (nmosd), an autoimmune astrocytopathy, causing also cns demyelination. |
2023-08-26 |
2023-09-07 |
Not clear |
| Fatin Aylia, Karn Johri, Riley Spencer, David Chu, Mehron Deriss, Davin Peng, Jonathan Eskenazi, Antonio K Li. A Patient With Miller Fisher Syndrome With Positive GQ1b and Aquaporin-4 Antibodies: Will There Be an Aquaporin-4 Antibody Associated Disorder? Cureus. vol 15. issue 8. 2023-08-15. PMID:37581199. |
there have been many advancements in the field of neuromyelitis optica and neuromyelitis optica spectrum disorder since the discovery of aquaporin-4 (aqp4) and myelin oligodendrocyte glycoprotein antibodies. |
2023-08-15 |
2023-09-07 |
Not clear |
| Sai Vishnu Vardhan Allu, Harsh R Parikh, Patrik Schmidt, Gabriel Alonso, Sneha Khanal, Ked Fortuzi, Misbahuddin Khaj. An Atypical Presentation of Chronic Inflammatory Myelin Degeneration in Neuromyelitis Optica (NMO). Cureus. vol 15. issue 7. 2023-08-14. PMID:37575757. |
neuromyelitis optica (nmo) is an autoimmune disorder characterized by aquaporin-4 (aqp4) igg autoantibodies. |
2023-08-14 |
2023-08-16 |
Not clear |
| Yoshiki Takai, Tatsuro Misu, Kazuo Fujihara, Masashi Aok. Pathology of myelin oligodendrocyte glycoprotein antibody-associated disease: a comparison with multiple sclerosis and aquaporin 4 antibody-positive neuromyelitis optica spectrum disorders. Frontiers in neurology. vol 14. 2023-08-07. PMID:37545724. |
compared to aquaporin 4 (aqp4) antibody-positive neuromyelitis optica spectrum disorders (nmosd), perivenous complement deposition is less common, but can be seen on myelinated fibers and on myelin degradation products within macrophages, resembling ms pattern ii pathology. |
2023-08-07 |
2023-08-14 |
human |
| Jessica A Kraker, John J Che. An update on optic neuritis. Journal of neurology. 2023-08-05. PMID:37542657. |
although most cases of optic neuritis (on) are classified as typical, meaning idiopathic or associated with multiple sclerosis, there is a growing understanding of atypical forms of optic neuritis such as antibody mediated aquaporin-4 (aqp4)-igg neuromyelitis optica spectrum disorder (nmosd) and the recently described entity, myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad). |
2023-08-05 |
2023-08-14 |
Not clear |
| Bret Silverglate, Xiaoyi Gao, Hannah P Lee, Peter Maliha, George T Grossber. The aquaporin-4 water channel and updates on its potential as a drug target for Alzheimer's Disease. Expert opinion on therapeutic targets. 2023-07-21. PMID:37475487. |
in this narrative review, we examine the history of aquaporin-4 (aqp4) as a therapeutic target for nmosd (neuromyelitis optica spectrum disorder) and as a potential therapeutic target for ad. |
2023-07-21 |
2023-08-14 |
Not clear |
| Sharon A Sagan, Zahra Moinfar, Carson E Moseley, Ravi Dandekar, Collin M Spencer, Alan S Verkman, Ole Petter Ottersen, Raymond A Sobel, John Sidney, Alessandro Sette, Mark S Anderson, Lawrence Steinman, Michael R Wilson, Joseph J Sabatino, Scott S Zamvi. T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 30. 2023-07-18. PMID:37463205. |
aquaporin-4 (aqp4)-specific th17 cells are thought to have a central role in neuromyelitis optica (nmo) pathogenesis. |
2023-07-18 |
2023-08-14 |
Not clear |
| Bahadar S Srichawla, Kajol Doshi, Seyedeh N Cheraghi, Shravan Sivakuma. The temporal relationship of paraneoplastic aquaporin-4-IgG seropositive neuromyelitis optica spectrum disorder (NMOSD) and breast cancer: a systematic review and meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-07-15. PMID:37453952. |
neuromyelitis optica spectrum disorder (nmosd) is an autoimmune astrocytopathy with evidence of neuroinflammation and demyelination that affects the central nervous system and is mediated by aquaporin-4 (aqp4) immunoglobulin (igg). |
2023-07-15 |
2023-08-14 |
Not clear |
| Yaxiu Fang, Hong Wu, Guanghui Liu, Ziang Li, Dongmei Wang, Yuping Ning, Suyue Pan, Yafang H. Secondary immunoreaction in patients with neurosyphilis and its relevance to clinical outcomes. Frontiers in neurology. vol 14. 2023-06-22. PMID:37346161. |
several reported cases of autoimmune conditions such as anti-nmdar encephalitis and neuromyelitis optica (aqp4) have been considered to be potentially secondary to |
2023-06-22 |
2023-08-14 |
Not clear |
| Shengnan Wang, Lin Pan, Rui Wu, Yanqing Shao, Mengru Xue, Hao Zhu, Wanwan Min, Xiangyu Zheng, Yekun Liang, Mingqin Zh. Oily fish and raw vegetable consumption can decrease the risk of AQP4-positive neuromyelitis optica spectrum disorders: a Mendelian-randomization study. Scientific reports. vol 13. issue 1. 2023-06-11. PMID:37296187. |
neuromyelitis optica spectrum disorders (nmosd) are severe inflammatory disorders of the central nervous system targeting aquaporin-4 (aqp4). |
2023-06-11 |
2023-08-14 |
human |
| Vyanka Redenbaugh, Nicholas H Chia, Laura Cacciaguerra, Jennifer A McCombe, Jan-Mendelt Tillema, John J Chen, A Sebastian Lopez Chiriboga, Elia Sechi, Yael Hacohen, Sean J Pittock, Eoin P Flanaga. Comparison of MRI T2-lesion evolution in pediatric MOGAD, NMOSD, and MS. Multiple sclerosis (Houndmills, Basingstoke, England). 2023-05-23. PMID:37218499. |
magnetic resonance imaging (mri) t2-lesions resolve more often in myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) than aquaporin-4 igg-positive neuromyelitis optica spectrum disorder (aqp4 + nmosd) and multiple sclerosis (ms) in adults but few studies analyzed children. |
2023-05-23 |
2023-08-14 |
Not clear |
| Kenichi Serizawa, Shota Miyake, Yoshichika Katsura, Keigo Yorozu, Mitsue Kurasawa, Haruna Tomizawa-Shinohara, Hideyuki Yasuno, Yoshihiro Matsumot. Intradermal AQP4 peptide immunization induces clinical features of neuromyelitis optica spectrum disorder in mice. Journal of neuroimmunology. vol 380. 2023-05-21. PMID:37210799. |
intradermal aqp4 peptide immunization induces clinical features of neuromyelitis optica spectrum disorder in mice. |
2023-05-21 |
2023-08-14 |
mouse |
| Kenichi Serizawa, Shota Miyake, Yoshichika Katsura, Keigo Yorozu, Mitsue Kurasawa, Haruna Tomizawa-Shinohara, Hideyuki Yasuno, Yoshihiro Matsumot. Intradermal AQP4 peptide immunization induces clinical features of neuromyelitis optica spectrum disorder in mice. Journal of neuroimmunology. vol 380. 2023-05-21. PMID:37210799. |
we challenged to create a mouse model of neuromyelitis optica spectrum disorder (nmosd) induced by aqp4 peptide immunization. |
2023-05-21 |
2023-08-14 |
mouse |
| Chirag Sunil Lalwani, Fida Faisal, Anjali Yadav, Sudheeran Kannoth, Vivek Nambiar, Sibi Gopinath, Anand Kumar, Saraf Udit Umesh, Jino Vincent, Sruthi Anoop, Annamma Mathai, Suprabha Panicke. The prevalence and clinical phenotype of dual seropositive neuromyelitis optica spectrum disorders at a national reference center in South Asia. Multiple sclerosis and related disorders. vol 75. 2023-05-01. PMID:37126965. |
neuromyelitis optica spectrum disorders (nmosd) is an autoimmune syndrome that is frequently positive for aquaporin 4 (aqp4) igg or myelin oligodendrocyte glycoproteins (mog) igg. |
2023-05-01 |
2023-08-14 |
Not clear |
| Kaoru Yamad. Multifaceted Roles of Aquaporins in the Pathogenesis of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047501. |
in the central nervous system, two major aquaporins (aqps), aqp1 and aqp4, and their potential involvements have been long implicated in the pathophysiology of many brain disorders such as brain edema and neuromyelitis optica. |
2023-04-13 |
2023-08-14 |
Not clear |
| Huijing Xu, Yushuang Gong, Yang Jiao, Jian Guo, Ling Zhao, Juechen Yang, Haibin Tong, Meiyan Sun, Miao L. Inhibition of Neuromyelitis Optica Immunoglobulin G Binding to Aquaporin-4 by the Small Molecule Blocker Melanthioidine. Current pharmaceutical design. 2023-03-31. PMID:36998134. |
the binding of neuromyelitis optica immunoglobulin g (nmo-igg) and aquaporin-4 (aqp4) on the surface of astrocytes in the serum and cerebrospinal fluid is the main pathogenesis of nmo. |
2023-03-31 |
2023-08-14 |
Not clear |
| Negar Moheb, John J Che. The neuro-ophthalmological manifestations of NMOSD and MOGAD-a comprehensive review. Eye (London, England). 2023-03-17. PMID:36928226. |
however, since the completion of the ontt, there has been the discovery of aquaporin-4 (aqp4) and myelin oligodendrocyte glycoprotein (mog) antibodies, which are biomarkers for neuromyelitis optica spectrum disorder (nmosd) and mog antibody-associated disease (mogad), respectively. |
2023-03-17 |
2023-08-14 |
Not clear |
| Bin Gou, Ping Yang, Jinzhou Feng, Yongmei Li, Gen Huang, Jiafeng Shi, Lu Wen, Xiuming Guo, Peng Zheng, Gang Y. The case report of AQP4 and MOG IgG double positive NMOSD treated with subcutaneous Ofatumumab. Journal of neuroimmunology. vol 376. 2023-01-30. PMID:36716560. |
neuromyelitis optica spectrum disorders (nmosd) is an autoimmune demyelinating disease with igg against aquaporin 4 (aqp4) in more than two thirds of patients. |
2023-01-30 |
2023-08-14 |
Not clear |
| Ming Xiao, Jiaoyu Hou, Mengmeng Xu, Shao Li, Baoxue Yan. Aquaporins in Nervous System. Advances in experimental medicine and biology. vol 1398. 2023-01-30. PMID:36717489. |
aqp4, the predominant water channel in the cns, is involved both in the astrocyte swelling of cytotoxic edema and the resolution of vasogenic edema and is of pivotal importance in the pathology of brain disorders such as neuromyelitis optica, brain tumors, and neurodegenerative disorders. |
2023-01-30 |
2023-08-14 |
Not clear |