| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jay Pundavela, Ashley Hall, Samantha Anne Dinglasan, Kwangmin Choi, Tilat A Rizvi, Bruce C Trapnell, Jianqiang Wu, Nancy Ratne. Granulocyte-Macrophage Colony Stimulating Factor Receptor Contributes to Plexiform Neurofibroma Initiation. Cancers. vol 17. issue 5. 2025-03-13. PMID:40075752. |
plexiform neurofibroma (pnf) is an immune cell-rich peripheral nerve sheath tumor that develops primarily in individuals with neurofibromatosis type 1 (nf1). |
2025-03-13 |
2025-03-15 |
Not clear |
| Paulina Sobieraj, Monika Bekiesińska-Figatowsk. Atypical Pelvic Tumors in Children. Cancers. vol 17. issue 4. 2025-02-26. PMID:40002214. |
additionally, tumors originating from the nervous system, including neuroblastoma (nbl) and plexiform neurofibroma (pnf), associated and not associated with neurofibromatosis type 1 (nf1), are discussed. |
2025-02-26 |
2025-02-28 |
Not clear |
| Micah Rambo, Isheka Agarwala, Camdyn Vanek, Yuxin Xiao, Emma Brown, K L Mill. Schwann Cells Deficient in Neurofibromin Lack Sensitivity to Their Biomechanical Microenvironment. Genes, chromosomes & cancer. vol 64. issue 2. 2025-02-25. PMID:39996425. |
plexiform neurofibromas (pnfs) are benign tumors of the peripheral nervous system that affect approximately 30% of people with neurofibromatosis type 1 (nf1). |
2025-02-25 |
2025-02-27 |
Not clear |
| Millicent S Curlee, Mary Anne Toledo-Tamula, Melissa Baker, Daniel Wikstrom, Cynthia Harrison, Amanda Rhodes, Margaret Fagan, Cecilia Tibery, Pamela L Wolters, Brigitte C Widemann, Andrea M Gross, Staci Marti. A Mixed Methods Study of Medication Adherence in Adults with Neurofibromatosis Type 1 (NF1) on a Clinical Trial of Selumetinib. Cancers. vol 17. issue 2. 2025-01-25. PMID:39858077. |
oral therapeutic options for plexiform neurofibromas (pns) in individuals with neurofibromatosis type 1 (nf1) are receiving attention in clinical research. |
2025-01-25 |
2025-01-28 |
Not clear |
| Yulia Dinikina, Marina Dorofeeva, Fatima Nakhushev. Selumetinib for children with neurofibromatosis type 1 and plexiform neurofibromas that can't be removed by surgery, and impact on how the condition affects caregivers: a plain language summary. Journal of comparative effectiveness research. 2025-01-21. PMID:39835668. |
some children with nf1 develop non-cancerous nerve tumors called plexiform neurofibromas. |
2025-01-21 |
2025-01-23 |
Not clear |
| Yulia Dinikina, Marina Dorofeeva, Fatima Nakhushev. Selumetinib for children with neurofibromatosis type 1 and plexiform neurofibromas that can't be removed by surgery, and impact on how the condition affects caregivers: a plain language summary. Journal of comparative effectiveness research. 2025-01-21. PMID:39835668. |
this plain language summary includes important findings from two selumetinib studies in children with nf1 and inoperable plexiform neurofibromas: the sprint selumetinib studies are part of a clinical study program that looked at how well selumetinib works in treating children with symptomatic, inoperable plexiform neurofibromas. |
2025-01-21 |
2025-01-23 |
Not clear |
| Yulia Dinikina, Marina Dorofeeva, Fatima Nakhushev. Selumetinib for children with neurofibromatosis type 1 and plexiform neurofibromas that can't be removed by surgery, and impact on how the condition affects caregivers: a plain language summary. Journal of comparative effectiveness research. 2025-01-21. PMID:39835668. |
the nf1 caregivers experience study is a related study where caregivers shared their experiences of caring for children with nf1and plexiform neurofibromas. |
2025-01-21 |
2025-01-23 |
Not clear |
| Andrea M Gross, Geraldine O'Sullivan Coyne, Eva Dombi, Cecilia Tibery, William G Herrick, Staci Martin, Steven P Angus, Jack F Shern, Steven D Rhodes, Jared C Foster, Larry V Rubinstein, Andrea Baldwin, Christopher Davis, Shelley A H Dixon, Margaret Fagan, Mary Jane Ong, Pamela L Wolters, Mary Anne Tamula, Olivia Reid, Hari Sankaran, Fang Fang, Jeevan Prasaad Govindharajulu, Alice T Browne, Rosandra N Kaplan, Kara Heisey, Thomas J On, Xiaoling Xuei, Xiyuan Zhang, Barry C Johnson, Ralph E Parchment, D Wade Clapp, Apurva K Srivastava, James H Doroshow, Alice P Chen, Brigitte C Wideman. Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial. Nature medicine. vol 31. issue 1. 2025-01-21. PMID:39762421. |
selumetinib in adults with nf1 and inoperable plexiform neurofibroma: a phase 2 trial. |
2025-01-21 |
2025-01-24 |
human |
| Andrea M Gross, Geraldine O'Sullivan Coyne, Eva Dombi, Cecilia Tibery, William G Herrick, Staci Martin, Steven P Angus, Jack F Shern, Steven D Rhodes, Jared C Foster, Larry V Rubinstein, Andrea Baldwin, Christopher Davis, Shelley A H Dixon, Margaret Fagan, Mary Jane Ong, Pamela L Wolters, Mary Anne Tamula, Olivia Reid, Hari Sankaran, Fang Fang, Jeevan Prasaad Govindharajulu, Alice T Browne, Rosandra N Kaplan, Kara Heisey, Thomas J On, Xiaoling Xuei, Xiyuan Zhang, Barry C Johnson, Ralph E Parchment, D Wade Clapp, Apurva K Srivastava, James H Doroshow, Alice P Chen, Brigitte C Wideman. Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial. Nature medicine. vol 31. issue 1. 2025-01-21. PMID:39762421. |
the mek inhibitor selumetinib induces objective responses and provides clinical benefit in children with neurofibromatosis type 1 (nf1) and inoperable plexiform neurofibromas (pns). |
2025-01-21 |
2025-01-24 |
human |
| Biagio de Brons, Britt Dhaenens, Rick van Minkelen, Rianne Oostenbrin. Identification of the Determinants of Plexiform Neurofibroma Morbidity in Pediatric and Young Adult Neurofibromatosis Type 1 Patients: A Pilot Multivariate Approach. Cancers. vol 17. issue 1. 2025-01-11. PMID:39796750. |
plexiform neurofibromas (pns) are histologically benign peripheral nerve sheath tumors associated with neurofibromatosis type 1 (nf1) and often lead to significant morbidity due to growth. |
2025-01-11 |
2025-01-14 |
Not clear |
| Wael A Alsakran, Nada Alyousef, Abrar A Alhawsawi, Abeer A Aljahdali, Sahar M Elkhamar. An Atypical Finding of Peripheral Retinal Ischemia and Neovascularization in Neurofibromatosis Type 1: A Case Report. Cureus. vol 16. issue 12. 2025-01-06. PMID:39759687. |
nf1 typically presents with skin lesions, including freckles, café-au-lait macules, plexiform neurofibromas, and bony dysplasia, and is usually accompanied by a family history of the disorder. |
2025-01-06 |
2025-01-08 |
Not clear |
| Yoshihiro Nishida, Norie Nonobe, Hiroyuki Kidokoro, Taichi Kato, Takuya Takeichi, Kunihiro Ikuta, Hiroshi Urakawa, Tomohisa Sakai, Hiroshi Koike, Takeo Fujito, Shiro Imagam. Selumetinib for symptomatic, inoperable plexiform neurofibromas in pediatric patients with neurofibromatosis type 1: the first single-center real-world case series in Japan. Japanese journal of clinical oncology. 2025-01-05. PMID:39756805. |
in japan, selumetinib is used in pediatric patients with neurofibromatosis type 1 (nf1) and symptomatic inoperable plexiform neurofibroma (pn). |
2025-01-05 |
2025-01-08 |
Not clear |
| Zifu Zhou, Qingfeng Li, Ran Hu. SUCLG1 promotes aerobic respiration and progression in plexiform neurofibroma. International journal of oncology. vol 66. issue 2. 2025-01-03. PMID:39749698. |
plexiform neurofibromas (pnfs) are benign tumors that affect 20‑50% of patients with type i neurofibromatosis (nf1). |
2025-01-03 |
2025-01-05 |
Not clear |
| . [Expert consensus for full course management of plexiform neurofibroma (2025 edition)]. Zhonghua yi xue za zhi. vol 104. 2024-12-29. PMID:39734099. |
plexiform neurofibroma (pnf) is one of the common clinical manifestations of nf1. |
2024-12-29 |
2025-01-01 |
Not clear |
| Chenguang Zhang, Yilina Saibaidula, Yulou Luo, Jianghua O. Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report. Biomedical reports. vol 22. issue 2. 2024-12-25. PMID:39720298. |
skin mass excision was performed and histopathology confirmed the diagnosis of thoracic plexiform neurofibroma as a primary presentation of nf1. |
2024-12-25 |
2024-12-27 |
Not clear |
| Masafumi Sanefuji, Takuji Nakamura, Naoya Higuchi, Hidetaka Niizuma, Yasuhiro Kawachi, Tadashi Shiohama, Yuichi Yoshida, Akihiko Asahina, Muneaki Matsu. Clinical characteristics and management of plexiform neurofibromas in children with neurofibromatosis 1: A Japanese nationwide survey. Brain & development. vol 47. issue 1. 2024-11-17. PMID:39550983. |
to investigate the clinical characteristics and management of plexiform neurofibromas (pns) in japanese children with neurofibromatosis 1 (nf1) in the beginning of a new era of treatment with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (mek) inhibitor selumetinib. |
2024-11-17 |
2024-11-22 |
Not clear |
| Marie-Lena Schmalhofer, Said Farschtschi, Lan Kluwe, Victor Felix Mautner, Gerhard Adam, Lennart Well, Inka Risto. Whole-body MRI-based long-term evaluation of pediatric NF1 patients without initial tumor burden with evidence of newly developed peripheral nerve sheath tumors. Orphanet journal of rare diseases. vol 19. issue 1. 2024-11-05. PMID:39497113. |
patients with neurofibromatosis type 1 (nf1) can develop plexiform neurofibromas (pn). |
2024-11-05 |
2024-11-07 |
Not clear |
| Baochen Zhu, Yang Xiao, Ruiheng Liao, Hanxing Zhao, Xuewen Xu, Yan'ge Zhan. [Emergency management and perioperative strategies for intra-tumoral hemorrhage in neurofibromatosis type 1-related giant plexiform neurofibroma]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 38. issue 10. 2024-10-21. PMID:39433490. |
to review the emergency management and perioperative strategies for ruptured neurofibromatosis type 1 (nf1)-related giant plexiform neurofibroma (pnf), providing a systematic treatment protocol to improve the therapeutic outcomes and quality of life for patients with giant pnf. |
2024-10-21 |
2024-10-24 |
Not clear |
| Nour Al Ghriwati, Paige Little, Staci Martin, Mary Anne Tamula, Brigitte C Widemann, Pamela L Wolter. Parent-child discrepancies in reports of child psychosocial functioning in neurofibromatosis type 1. Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43). 2024-10-17. PMID:39418437. |
this study examined the concordance of parent proxy- and child self-report of child behavioral and social-emotional functioning on selected behavior assessment system for children-second edition subscales in families of children with nf1 and plexiform neurofibroma tumors (pnfs). |
2024-10-17 |
2024-10-20 |
Not clear |
| Andi Ahmad Thoriq Pratama, M Hidayat Surya Atmaj. The role of multimodality imaging in diffuse pelvicoabdominal plexiform neurofibroma: A rare case report. Radiology case reports. vol 19. issue 12. 2024-09-19. PMID:39296740. |
pelvicoabdominal plexiform neurofibroma is a rare and complicated form of type 1 neurofibromatosis (nf1), distinguished by developing benign nerve sheath tumors in the pelvis and abdomen. |
2024-09-19 |
2024-09-21 |
Not clear |