| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue Zhu, Yunyun Huang, Tianxiang Tang, Yunli Xi. HDAC1 and HDAC2 orchestrate Wnt signaling to regulate neural progenitor transition during brain development. iScience. vol 27. issue 9. 2024-09-03. PMID:39224519. |
tightly controlled neurogenesis is crucial for generating the precise number of neurons and establishing the intricate architecture of the cortex, with deficiencies often leading to neurodevelopmental disorders. |
2024-09-03 |
2024-09-05 |
Not clear |
| Kubra Cengiz, Islem Reki. Cortical morphological networks for profiling autism spectrum disorder using tensor component analysis. Frontiers in neurology. vol 15. 2024-07-19. PMID:39026578. |
atypical neurodevelopmental disorders such as autism spectrum disorder (asd) can alter the cortex morphology at different levels: (i) a low-order level where cortical regions are examined individually, (ii) a high-order level where the relationship between two cortical regions is considered, and (iii) a multi-view high-order level where the relationship between regions is examined across multiple brain views. |
2024-07-19 |
2024-07-21 |
human |
| Gareth Chapman, Julianna Determan, Haley Jetter, Komal Kaushik, Ramachandran Prakasam, Kristen L Krol. Defining cis-regulatory elements and transcription factors that control human cortical interneuron development. iScience. vol 27. issue 6. 2024-06-03. PMID:38827400. |
although human cortical interneurons (cins) are a minority population in the cerebral cortex, disruption of interneuron development is a frequent contributor to neurodevelopmental disorders. |
2024-06-03 |
2024-06-05 |
human |
| Shulin Luo, Lingyan Ren, Rongping Wang, Jianxin Hu, Wei Wei, Yurong Feng, Shengwen Huan. Functional analysis of a novel intronic variant of Heliyon. vol 10. issue 10. 2024-06-01. PMID:38818167. |
functional analysis of a novel intronic variant of autosomal recurrent primary microscopic (mcph, omim: 251200) is a neurodevelopmental disorder that is characterized by a noticeable decrease in brain size, particularly in the cerebral cortex, but with a normal brain structure and a non-progressive intellectual disability. |
2024-06-01 |
2024-06-02 |
Not clear |
| Ben Miller, Alexander Crider, Bhooma Aravamuthan, Rafael Galind. Human chorionic gonadotropin decreases cerebral cystic encephalomalacia and parvalbumin interneuron degeneration in a pro-inflammatory model of mouse neonatal hypoxia-ischemia. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585735. |
noting that parvalbumin immunoreactive interneurons have been broadly implicated in neurodevelopmental disorders, it is notable that hcg significantly improved the injury-mediated reduction of these neurons in the cerebral cortex, striatum and hippocampus. |
2024-04-08 |
2024-04-10 |
mouse |
| Felipe Morgado, Marlee M Vandewouw, Christopher Hammill, Elizabeth Kelley, Jennifer Crosbie, Russell Schachar, Muhammad Ayub, Robert Nicolson, Stelios Georgiades, Paul Arnold, Alana Iaboni, Azadeh Kushki, Margot J Taylor, Evdokia Anagnostou, Jason P Lerc. Behaviour-correlated profiles of cerebellar-cerebral functional connectivity observed in independent neurodevelopmental disorder cohorts. Translational psychiatry. vol 14. issue 1. 2024-04-03. PMID:38570480. |
the cerebellum, through its connectivity with the cerebral cortex, plays an integral role in regulating cognitive and affective processes, and its dysregulation can result in neurodevelopmental disorder (ndd)-related behavioural deficits. |
2024-04-03 |
2024-04-06 |
human |
| Francisca Cornejo, Nayhara Franchini, Bastián I Cortés, Daniela Elgueta, Gonzalo I Cancin. Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex. Frontiers in cell and developmental biology. vol 12. 2024-03-15. PMID:38487272. |
neurodevelopmental disorders are characterized by alterations in the development of the cerebral cortex, including aberrant changes in the number and function of neural cells. |
2024-03-15 |
2024-03-17 |
mouse |
| Evan Geller, Mark A Noble, Matheo Morales, Jake Gockley, Deena Emera, Severin Uebbing, Justin L Cotney, James P Noona. Massively parallel disruption of enhancers active in human neural stem cells. Cell reports. vol 43. issue 2. 2024-01-25. PMID:38271204. |
changes in gene regulation have been linked to the expansion of the human cerebral cortex and to neurodevelopmental disorders, potentially by altering neural progenitor proliferation. |
2024-01-25 |
2024-01-28 |
human |
| Qiuyu Guo, Sarah Wu, Daniel H Geschwin. Characterization of gene regulatory elements in human fetal cortical development: Enhancing our understanding of neurodevelopmental disorders and evolution. Developmental neuroscience. 2023-05-26. PMID:37231806. |
studying the development of human cortex is important in understanding the evolutionary changes occurring in humans relative to other primates, as well as in elucidating mechanisms underlying neurodevelopmental disorders. |
2023-05-26 |
2023-08-14 |
human |
| Jennine M Dawicki-McKenna, Alex J Felix, Elisa A Waxman, Congsheng Cheng, Defne A Amado, Paul T Ranum, Alexey Bogush, Lea V Dungan, Jean Ann Maguire, Alyssa L Gagne, Elizabeth A Heller, Deborah L French, Beverly L Davidson, Benjamin L Prosse. Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching. Nature communications. vol 14. issue 1. 2023-05-06. PMID:37149717. |
our data comprehensively map ptbp2-dependent alternative splicing in human neurons and cerebral cortex, guiding development of novel therapeutic tools to benefit neurodevelopmental disorders. |
2023-05-06 |
2023-08-14 |
human |
| Xin Liu, Jie Yang, Zhaoyi Li, Ruonan Liu, Xinyu Wu, Zhongtian Zhang, Liangxue Lai, Zhanjun Li, Yuning Son. YIPF5 (p.W218R) mutation induced primary microcephaly in rabbits. Neurobiology of disease. 2023-05-04. PMID:37142085. |
further investigation based on model rabbit elucidated that altered yipf5 function in cortical neurons could lead to endoplasmic reticulum stress and neurodevelopmental disorders, interference of the generation of apical progenitors (aps), the first generation of progenitors in the developing cortex. |
2023-05-04 |
2023-08-14 |
mouse |
| Tanzila Mukhtar, Jeremie Breda, Manal A Adam, Marcelo Boareto, Pascal Grobecker, Zahra Karimaddini, Alice Grison, Katja Eschbach, Ramakrishnan Chandrasekhar, Swen Vermeul, Michal Okoniewski, Mikhail Pachkov, Corey C Harwell, Suzana Atanasoski, Christian Beisel, Dagmar Iber, Erik van Nimwegen, Verdon Taylo. Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis. The EMBO journal. 2022-11-08. PMID:36345783. |
the cerebral cortex contains billions of neurons, and their disorganization or misspecification leads to neurodevelopmental disorders. |
2022-11-08 |
2023-08-14 |
Not clear |
| H Moriah Sokolowski, Brian Levin. Common neural substrates of diverse neurodevelopmental disorders. Brain : a journal of neurology. 2022-10-27. PMID:36299249. |
considering network-level commonalities reported in studies of neurodevelopmental disorders, variability in multimodal association cortex connectivity may reflect a shared origin of seemingly distinct neurodevelopmental disorders. |
2022-10-27 |
2023-08-14 |
Not clear |
| Robin Scharrenberg, Melanie Richter, Ole Johanns, Durga Praveen Meka, Tabitha Rücker, Nadeem Murtaza, Zsuzsa Lindenmaier, Jacob Ellegood, Anne Naumann, Bing Zhao, Birgit Schwanke, Jan Sedlacik, Jens Fiehler, Ileana L Hanganu-Opatz, Jason P Lerch, Karun K Singh, Froylan Calderon de And. TAOK2 rescues autism-linked developmental deficits in a 16p11.2 microdeletion mouse model. Molecular psychiatry. 2022-09-19. PMID:36123424. |
despite numerous advances that have been made in understanding neuronal differentiation and cortex development, our knowledge regarding the impact of specific genes associated with neurodevelopmental disorders on these processes is still limited. |
2022-09-19 |
2023-08-14 |
mouse |
| Nora Bölicke, Mareike Alber. Polycomb-mediated gene regulation in human brain development and neurodevelopmental disorders. Developmental neurobiology. 2022-04-06. PMID:35384339. |
in this review, we will discuss our growing understanding of how pcg regulation affects human cortex development, based on studies in murine model systems, but focusing mostly on findings obtained from examining impaired pcg activity in the context of human neurodevelopmental disorders and cancer. |
2022-04-06 |
2023-08-13 |
mouse |
| Leora D'Souza, Asha S Channakkar, Bhavana Muralidhara. Chromatin remodelling complexes in cerebral cortex development and neurodevelopmental disorders. Neurochemistry international. vol 147. 2021-09-07. PMID:33964373. |
chromatin remodelling complexes in cerebral cortex development and neurodevelopmental disorders. |
2021-09-07 |
2023-08-13 |
mouse |
| Yuko Okamoto, Ryo Kitada, Takanori Kochiyama, Hiroaki Naruse, Kai Makita, Motohide Miyahara, Hidehiko Okazawa, Hirotaka Kosak. Visual Body Part Representation in the Lateral Occipitotemporal Cortex in Children/Adolescents and Adults. Cerebral cortex communications. vol 1. issue 1. 2021-07-24. PMID:34296088. |
the lateral occipitotemporal cortex (lotc) that responds to human bodies and body parts has been implicated in social development and neurodevelopmental disorders like autism spectrum disorder (asd). |
2021-07-24 |
2023-08-13 |
human |
| A Vogel Ciernia, B I Laufer, H Hwang, K W Dunaway, C E Mordaunt, R L Coulson, D H Yasui, J M LaSall. Epigenomic Convergence of Neural-Immune Risk Factors in Neurodevelopmental Disorder Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 2. 2021-06-15. PMID:31240313. |
epigenomic convergence of neural-immune risk factors in neurodevelopmental disorder cortex. |
2021-06-15 |
2023-08-13 |
human |
| Marissa Co, Stephanie L Hickey, Ashwinikumar Kulkarni, Matthew Harper, Genevieve Konopk. Cortical Foxp2 Supports Behavioral Flexibility and Developmental Dopamine D1 Receptor Expression. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-15. PMID:31711176. |
genetic studies have associated foxp2 variation with speech and language disorders and other neurodevelopmental disorders (ndds) involving pathology of the cortex. |
2021-06-15 |
2023-08-13 |
mouse |
| Martina Pecimonova, Jan Radvanszky, David Smolak, Jaroslav Budis, Michal Lichvar, Diana Kristinova, Ivica Rozova, Jan Turna, Tomas Szeme. Admixed phenotype of NEDD4L associated periventricular nodular heterotopia: A case report. Medicine. vol 100. issue 22. 2021-06-15. PMID:34087865. |
periventricular nodular heterotopia-7 (pvnh7) is a neurodevelopmental disorder associated with improper neuronal migration during neurogenesis in cortex development caused by pathogenic variants in the nedd4l gene. |
2021-06-15 |
2023-08-13 |
Not clear |