All Relations between Neurodegenerative Diseases and substantia nigra compacta

Publication Sentence Publish Date Extraction Date Species
Diana A Quintero-Espinosa, Marlene Jimenez-Del-Rio, Carlos Velez-Pard. LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress. Neurochemical research. 2024-06-07. PMID:38847910. parkinson's disease (pd) is a complex multifactorial progressive neurodegenerative disease characterized by locomotor alteration due to the specific deterioration of dopaminergic (daergic) neurons in the substantia nigra pars compacta (snpc). 2024-06-07 2024-06-10 human
Fernanda Vidal Carvalho, Harold E Landis, Bruk Getachew, Victor Diogenes Amaral Silva, Paulo R Ribeiro, Michael Aschner, Yousef Tizab. Iron toxicity, ferroptosis and microbiota in Parkinson's disease: Implications for novel targets. Advances in neurotoxicology. vol 11. 2024-05-23. PMID:38770370. parkinson's disease (pd) is a progressive neurodegenerative disease characterized by loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2024-05-23 2024-05-27 Not clear
Xiang Tao, Wenfei Zhang, Chen Chen, Yang Tao, Yun Tao, Zhibiao Chen, Ge Zhan. miR-101a-3p/ROCK2 axis regulates neuronal injury in Parkinson's disease models. Aging. vol 16. 2024-05-22. PMID:38775730. parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2024-05-22 2024-05-27 Not clear
Jindong Zhao, Ji Wang, Kunying Zhao, Yuxiao Zhang, Weiyan H. Protopanaxadiols Eliminate Behavioral Impairments and Mitochondrial Dysfunction in Parkinson's Disease Mice Model. Neurochemical research. 2024-03-29. PMID:38551796. currently, there are no effective therapies to cure parkinson's disease (pd), which is the second most common neurodegenerative disease primarily characterized by motor dysfunction and degeneration of dopaminergic neurons in the substantia nigra pars compacta (snc). 2024-03-29 2024-04-01 mouse
Bandar Alharbi, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Engy Elekhnawy, Hind Alharbi, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batih. Role of GABA pathway in motor and non-motor symptoms in Parkinson's disease: a bidirectional circuit. European journal of medical research. vol 29. issue 1. 2024-03-28. PMID:38539252. parkinson's disease (pd) is a progressive neurodegenerative disease as a result of the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-03-28 2024-03-30 Not clear
Kandatege Wimalasena, Oluwatosin Adetuyi, Maya Eldan. Metabolic energy decline coupled dysregulation of catecholamine metabolism in physiologically highly active neurons: implications for selective neuronal death in Parkinson's disease. Frontiers in aging neuroscience. vol 16. 2024-03-07. PMID:38450382. parkinson's disease (pd) is an age-related irreversible neurodegenerative disease which is characterized as a progressively worsening involuntary movement disorder caused by the loss of dopaminergic (da) neurons in substantia nigra pars compacta (snpc). 2024-03-07 2024-03-09 Not clear
Patrick J Kearney, Yuanxi Zhang, Marianna Liang, Yanglan Tan, Elizabeth Kahuno, Tucker L Conklin, Rita R Fagan, Rebecca G Pavchinskiy, Scott A Shaffer, Zhenyu Yue, Haley E Melikia. Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability. NPJ Parkinson's disease. vol 10. issue 1. 2024-02-23. PMID:38395968. parkinson's disease (pd) is the second most prevalent neurodegenerative disease and arises from dopamine (da) neuron death selectively in the substantia nigra pars compacta (snc). 2024-02-23 2024-02-26 mouse
Jiannan Wang, Lijun Dai, Sichun Chen, Zhaohui Zhang, Xin Fang, Zhentao Zhan. Protein-protein interactions regulating α-synuclein pathology. Trends in neurosciences. 2024-02-14. PMID:38355325. parkinson's disease (pd) is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) and the formation of lewy bodies (lbs). 2024-02-14 2024-02-17 Not clear
Mudiwa N Muwanigwa, Jennifer Modamio-Chamarro, Paul M A Antony, Gemma Gomez-Giro, Rejko Krüger, Silvia Bolognin, Jens C Schwambor. Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease. Molecular and cellular neurosciences. 2024-02-02. PMID:38307302. parkinson's disease (pd) is a complex, progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta in the midbrain. 2024-02-02 2024-02-05 human
Hayder M Al-Kuraishy, Sadiq M Al-Hamash, Majid S Jabir, Ali I Al-Gareeb, Ali K Albuhadily, Salim Albukhaty, Ghassan M Sulaima. The classical and non-classical axes of renin-angiotensin system in Parkinson disease: The bright and dark side of the moon. Ageing research reviews. 2024-01-18. PMID:38237699. parkinson disease (pd) is a common brain neurodegenerative disease due to progressive degeneration of the dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-01-18 2024-01-21 Not clear
Surabhi Shastry, Junkai Hu, Mingyao Ying, Xiaobo Ma. Cell Therapy for Parkinson's Disease. Pharmaceutics. vol 15. issue 12. 2023-12-23. PMID:38139997. parkinson's disease (pd) is a neurodegenerative disease characterized by the progressive loss of dopaminergic neurons of the substantia nigra pars compacta with a reduction in dopamine concentration in the striatum. 2023-12-23 2023-12-25 Not clear
Myung Ji Kim, Su Hee Cho, Yongbo Seo, Sang-Dae Kim, Hae-Chul Park, Bum-Joon Ki. Neuro-Restorative Effect of Nimodipine and Calcitriol in 1-Methyl 4-Phenyl 1,2,3,6 Tetrahydropyridine-Induced Zebrafish Parkinson's Disease Model. Journal of Korean Neurosurgical Society. 2023-12-22. PMID:38130142. parkinson's disease (pd) is one of the most prevalent neurodegenerative diseases, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. 2023-12-22 2023-12-24 human
Meng-Fan Yao, Tao Dang, Hua-Jun Wang, Xiao-Zhong Zhu, Chen Qia. Mitochondrial homeostasis regulation: A promising therapeutic target for Parkinson's disease. Behavioural brain research. 2023-12-16. PMID:38103871. parkinson's disease (pd) is a neurodegenerative disease characterized by progressive loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snc) and the presence of lewy bodies (lbs) or lewy neurites (lns) which consist of α-synuclein (α-syn) and a complex mix of other biomolecules. 2023-12-16 2023-12-21 human
Haydar M Al-Kuraishy, Ali I Al-Gareeb, Athanasios Alexiou, Marios Papadakis, Mostafa M Bahaa, Aya Talal Zaidalkiani, Ammar Al-Faraga, Gaber El-Saber Batih. Calprotectin in Parkinsonian Disease: Anticipation and Dedication. Ageing research reviews. 2023-11-26. PMID:38008403. parkinson's disease (pd) is a neurodegenerative disease due to degeneration of dopaminergic neurons (dns) in the substantia nigra pars compacta (snpc). 2023-11-26 2023-11-28 Not clear
Ridhima Vij, Alan Prossin, Mallika Tripathy, Hosu Kim, Hyeonggeun Park, Thanh Cheng, Djamchid Lotfi, Donna Chan. Long-term, repeated doses of intravenous autologous mesenchymal stem cells for a patient with Parkinson's disease: a case report. Frontiers in neurology. vol 14. 2023-10-16. PMID:37840944. parkinson's disease (pd) is a neurodegenerative disease that involves the loss of dopaminergic neurons in the substantia nigra pars compacta of the basal ganglia. 2023-10-16 2023-11-08 Not clear
Can-Tang Zhang, Deng-Li Qin, Xia-Yin Cao, Jia-Shuo Kan, Xin-Xing Huang, Dian-Shuai Gao, Jin Ga. Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA domain 1 expression. iScience. vol 26. issue 7. 2023-08-03. PMID:37534182. parkinson's disease (pd) is a neurodegenerative disease characterized by selective loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc). 2023-08-03 2023-08-14 Not clear
Zhongting Zhao, Zheng Li, Fangning Du, Yixin Wang, Yue Wu, Kah-Leong Lim, Lin Li, Naidi Yang, Changmin Yu, Chengwu Zhan. Linking Heat Shock Protein 70 and Parkin in Parkinson's Disease. Molecular neurobiology. 2023-08-01. PMID:37526897. parkinson's disease (pd) is a neurodegenerative disease that affects millions of elderly people worldwide and is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2023-08-01 2023-08-14 Not clear
Qin Li, Shuai Li, Jiankang Fang, Chao Yang, Xia Zhao, Qing Wang, Wenshu Zhou, Wenhua Zhen. Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway. Molecules (Basel, Switzerland). vol 28. issue 14. 2023-07-29. PMID:37513399. parkinson's disease (pd) is an age-related, progressive neurodegenerative disease characterized by the gradual and massive loss of dopaminergic neurons in the substantia nigra pars compacta (snc). 2023-07-29 2023-08-14 Not clear
Tao Pan, Qi Xiao, Hui-Jie Fan, Lei Xu, Shao-Chen Qin, Li-Xia Yang, Xiao-Ming Jin, Bao-Guo Xiao, Bo Zhang, Cun-Gen Ma, Zhi Cha. Wuzi Yanzong Pill relieves MPTP-induced motor dysfunction and neuron loss by inhibiting NLRP3 inflammasome-mediated neuroinflammation. Metabolic brain disease. 2023-07-20. PMID:37470879. parkinson disease (pd) is an age-related neurodegenerative disease, which is associated with the loss of dopaminergic neurons (da neurons) in the substantia nigra pars compacta (snpc), and neuroinflammation may lead to the occurrence of pd. 2023-07-20 2023-08-14 mouse
Sheikh Azimullah, Mohamed Fizur Nagoor Meeran, Khatija Ayoob, Seenipandi Arunachalam, Shreesh Ojha, Rami Beira. Tannic Acid Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Inhibiting Inflammation, Oxidative Stress, Apoptosis, and Glutamate Toxicity in Rats. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373023. parkinson's disease (pd), a movement disorder, is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) region of the brain. 2023-06-28 2023-08-14 human