All Relations between Neurodegenerative Diseases and substantia nigra compacta

Publication Sentence Publish Date Extraction Date Species
Raelynn Brassard, Elena Arutyunova, Emmanuella Takyi, L Michel Espinoza-Fonseca, Howard Young, Nicolas Touret, M Joanne Lemieu. Transmembrane Parkinson's Disease mutation of PINK1 leads to altered mitochondrial anchoring. The Journal of biological chemistry. 2025-02-05. PMID:39909370. parkinson's disease (pd) is a devastating neurodegenerative disease resulting from the death of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. 2025-02-05 2025-02-08 Not clear
Julia C Fitzgerald, Ying Sun, Frederek Reinecke, Elisabeth Bauer, Olga Garaschuk, Philipp J Kahle, Friederike Pfeiffe. Interactions of Oligodendrocyte Precursor Cells and Dopaminergic Neurons in the Mouse Substantia Nigra. Journal of neurochemistry. vol 169. issue 1. 2025-01-28. PMID:39871627. parkinson's disease (pd) is a prevalent neurodegenerative disease caused by the death of dopaminergic neurons within the substantia nigra pars compacta (snpc) region of the midbrain. 2025-01-28 2025-01-30 mouse
Joana Sobral, Nuno Empadinhas, Ana Raquel Esteves, Sandra Morais Cardos. Impact of Nutrition on the Gut Microbiota: Implications for Parkinson's Disease. Nutrition reviews. 2025-01-15. PMID:39812804. parkinson's disease (pd) is a multifactorial neurodegenerative disease that is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta and by the anomalous accumulation of α-synuclein aggregates into lewy bodies and lewy neurites. 2025-01-15 2025-01-17 human
Sa Weon Hong, Rachel Page, Penelope Truma. Smoking, coffee intake, and Parkinson's disease: potential protective mechanisms and components. Neurotoxicology. 2024-12-19. PMID:39701424. parkinson's disease (pd) is a common progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-12-19 2024-12-22 Not clear
Ke Xu, Yu Zhang, Yue Shi, Yake Zhang, Chengguang Zhang, Tianjiao Wang, Peizhu Lv, Yan Bai, Shun Wan. Circadian rhythm disruption: a potential trigger in Parkinson's disease pathogenesis. Frontiers in cellular neuroscience. vol 18. 2024-11-14. PMID:39539340. parkinson's disease (pd) is a neurodegenerative disease characterized by the gradual loss of dopaminergic neurons in the substantia nigra pars compacta (snpc), abnormal accumulation of α-synuclein (α-syn), and activation of microglia leading to neuroinflammation. 2024-11-14 2024-11-17 Not clear
Anna Nelke, Silvia García-López, Javier R Caso, Marta P Pereir. The therapeutic use of clonal neural stem cells in experimental Parkinson´s disease. Stem cell research & therapy. vol 15. issue 1. 2024-10-10. PMID:39385216. parkinson´s disease (pd), the second most common neurodegenerative disease in the world, is characterized by the death or impairment of dopaminergic neurons (dan) in the substantia nigra pars compacta and dopamine depletion in the striatum. 2024-10-10 2024-10-12 mouse
Xiaowei Sun, Rou Gu, Jie Ba. Differentiation and regulation of CD4 Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-08-17. PMID:39153043. differentiation and regulation of cd4 parkinson's disease (pd) is the second most common neurodegenerative disease, and its hallmark pathological features are the loss of dopaminergic (da) neurons in the midbrain substantia nigra pars compacta (snpc) and the accumulation of alpha-synuclein (α-syn). 2024-08-17 2024-08-20 Not clear
Patrick Oluwole Abolarin, Abdulbasit Amin, Abdulrazaq Bidemi Nafiu, Olalekan Michael Ogundele, Bamidele Victor Owoyel. Optimization of Parkinson's disease therapy with plant extracts and nutrition's evolving roles. IBRO neuroscience reports. vol 17. 2024-06-14. PMID:38872839. parkinson's disease (pd) is a neurodegenerative disease characterized by death of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-06-14 2024-06-16 Not clear
Diana A Quintero-Espinosa, Marlene Jimenez-Del-Rio, Carlos Velez-Pard. LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress. Neurochemical research. 2024-06-07. PMID:38847910. parkinson's disease (pd) is a complex multifactorial progressive neurodegenerative disease characterized by locomotor alteration due to the specific deterioration of dopaminergic (daergic) neurons in the substantia nigra pars compacta (snpc). 2024-06-07 2024-06-10 human
Fernanda Vidal Carvalho, Harold E Landis, Bruk Getachew, Victor Diogenes Amaral Silva, Paulo R Ribeiro, Michael Aschner, Yousef Tizab. Iron toxicity, ferroptosis and microbiota in Parkinson's disease: Implications for novel targets. Advances in neurotoxicology. vol 11. 2024-05-23. PMID:38770370. parkinson's disease (pd) is a progressive neurodegenerative disease characterized by loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2024-05-23 2024-05-27 Not clear
Xiang Tao, Wenfei Zhang, Chen Chen, Yang Tao, Yun Tao, Zhibiao Chen, Ge Zhan. miR-101a-3p/ROCK2 axis regulates neuronal injury in Parkinson's disease models. Aging. vol 16. 2024-05-22. PMID:38775730. parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in substantia nigra pars compacta (snpc). 2024-05-22 2024-05-27 Not clear
Jindong Zhao, Ji Wang, Kunying Zhao, Yuxiao Zhang, Weiyan H. Protopanaxadiols Eliminate Behavioral Impairments and Mitochondrial Dysfunction in Parkinson's Disease Mice Model. Neurochemical research. 2024-03-29. PMID:38551796. currently, there are no effective therapies to cure parkinson's disease (pd), which is the second most common neurodegenerative disease primarily characterized by motor dysfunction and degeneration of dopaminergic neurons in the substantia nigra pars compacta (snc). 2024-03-29 2024-04-01 mouse
Bandar Alharbi, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Engy Elekhnawy, Hind Alharbi, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batih. Role of GABA pathway in motor and non-motor symptoms in Parkinson's disease: a bidirectional circuit. European journal of medical research. vol 29. issue 1. 2024-03-28. PMID:38539252. parkinson's disease (pd) is a progressive neurodegenerative disease as a result of the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-03-28 2024-03-30 Not clear
Kandatege Wimalasena, Oluwatosin Adetuyi, Maya Eldan. Metabolic energy decline coupled dysregulation of catecholamine metabolism in physiologically highly active neurons: implications for selective neuronal death in Parkinson's disease. Frontiers in aging neuroscience. vol 16. 2024-03-07. PMID:38450382. parkinson's disease (pd) is an age-related irreversible neurodegenerative disease which is characterized as a progressively worsening involuntary movement disorder caused by the loss of dopaminergic (da) neurons in substantia nigra pars compacta (snpc). 2024-03-07 2024-03-09 Not clear
Patrick J Kearney, Yuanxi Zhang, Marianna Liang, Yanglan Tan, Elizabeth Kahuno, Tucker L Conklin, Rita R Fagan, Rebecca G Pavchinskiy, Scott A Shaffer, Zhenyu Yue, Haley E Melikia. Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability. NPJ Parkinson's disease. vol 10. issue 1. 2024-02-23. PMID:38395968. parkinson's disease (pd) is the second most prevalent neurodegenerative disease and arises from dopamine (da) neuron death selectively in the substantia nigra pars compacta (snc). 2024-02-23 2024-02-26 mouse
Jiannan Wang, Lijun Dai, Sichun Chen, Zhaohui Zhang, Xin Fang, Zhentao Zhan. Protein-protein interactions regulating α-synuclein pathology. Trends in neurosciences. 2024-02-14. PMID:38355325. parkinson's disease (pd) is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) and the formation of lewy bodies (lbs). 2024-02-14 2024-02-17 Not clear
Mudiwa N Muwanigwa, Jennifer Modamio-Chamarro, Paul M A Antony, Gemma Gomez-Giro, Rejko Krüger, Silvia Bolognin, Jens C Schwambor. Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease. Molecular and cellular neurosciences. 2024-02-02. PMID:38307302. parkinson's disease (pd) is a complex, progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta in the midbrain. 2024-02-02 2024-02-05 human
Hayder M Al-Kuraishy, Sadiq M Al-Hamash, Majid S Jabir, Ali I Al-Gareeb, Ali K Albuhadily, Salim Albukhaty, Ghassan M Sulaima. The classical and non-classical axes of renin-angiotensin system in Parkinson disease: The bright and dark side of the moon. Ageing research reviews. 2024-01-18. PMID:38237699. parkinson disease (pd) is a common brain neurodegenerative disease due to progressive degeneration of the dopaminergic neurons in the substantia nigra pars compacta (snpc). 2024-01-18 2024-01-21 Not clear
Surabhi Shastry, Junkai Hu, Mingyao Ying, Xiaobo Ma. Cell Therapy for Parkinson's Disease. Pharmaceutics. vol 15. issue 12. 2023-12-23. PMID:38139997. parkinson's disease (pd) is a neurodegenerative disease characterized by the progressive loss of dopaminergic neurons of the substantia nigra pars compacta with a reduction in dopamine concentration in the striatum. 2023-12-23 2023-12-25 Not clear
Myung Ji Kim, Su Hee Cho, Yongbo Seo, Sang-Dae Kim, Hae-Chul Park, Bum-Joon Ki. Neuro-Restorative Effect of Nimodipine and Calcitriol in 1-Methyl 4-Phenyl 1,2,3,6 Tetrahydropyridine-Induced Zebrafish Parkinson's Disease Model. Journal of Korean Neurosurgical Society. 2023-12-22. PMID:38130142. parkinson's disease (pd) is one of the most prevalent neurodegenerative diseases, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. 2023-12-22 2023-12-24 human