| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sharan Paul, Warunee Dansithong, Karla P Figueroa, Mandi Gandelman, Pravin Hivare, Daniel R Scoles, Stefan M Puls. Staufen2 dysregulation in neurodegenerative disease. The Journal of biological chemistry. 2025-02-15. PMID:39955058. |
previously, we showed that its paralog staufen1 (stau1) was overabundant in cellular and mouse models of neurodegenerative diseases and amyotrophic lateral sclerosis (als) patient spinal cord. |
2025-02-15 |
2025-02-18 |
mouse |
| Hengsen Cai, Jiajun Huang, Wei Wang, Wentong Lin, Waqas Ahmed, Deng Lu, Jiewei Quan, Lukui Che. Characteristics of Parthenogenetic Stem Cells and Their Potential Treatment Strategy for Central Nervous System Diseases. Neuropsychiatric disease and treatment. vol 21. 2025-02-10. PMID:39926116. |
stem cells hold significant promise in treating neurological illnesses, such as stroke, spinal cord injury and neurodegenerative diseases. |
2025-02-10 |
2025-02-13 |
human |
| Matthew B Dopler, Muhammad I Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L Petersen, Esther H Daniel, Carlton L Cannon, Angelica Bautista, Kennedy D Blancher, Alysia M Bland, Kylie J Bond, Dominque A Davis, Jessica M Francois, Eliana J McCray, Justin M Morgan, Jessica L Pulliam, Zymir A Robinson, Mykia J Taylor, James A Dowell, Nigel J Cairns, Michael A Gitch. A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation. The FEBS journal. 2025-01-31. PMID:39887552. |
amyotrophic lateral sclerosis (als) is an incurable neurodegenerative disease that affects neurons in the brain and spinal cord, causing loss of muscle control, and eventually leads to death. |
2025-01-31 |
2025-02-02 |
Not clear |
| Michal Izrael, Judith Chebath, Kfir Molakandov, Michel Reve. Clinical perspective on pluripotent stem cells derived cell therapies for the treatment of neurodegenerative diseases. Advanced drug delivery reviews. 2025-01-29. PMID:39880333. |
furthermore, we provide an overview on progress and status of clinical trials done so far in treating neurodegenerative diseases such as spinal cord injury (sci), parkinson's disease (pd), and amyotrophic lateral sclerosis (als), as well as advances in retina diseases such as stargardt disease (a.k.a fundus flavimaculatus), retinitis pigmentosa (rp) and age-related macular degeneration (amd). |
2025-01-29 |
2025-02-01 |
human |
| Ruiqi Huang, Yanjing Zhu, Haokun Chen, Liqun Yu, Zhibo Liu, Yuchen Liu, Zhaojie Wang, Xiaolie He, Li Yang, Xu Xu, Yuxin Bai, Bairu Chen, Rongrong Zh. Progress in spinal cord organoid research: advancing understanding of neural development, disease modelling, and regenerative medicine. Biomaterials translational. vol 5. issue 4. 2025-01-28. PMID:39872925. |
this review synthesises recent advancements in sco technology, highlighting their role in modelling spinal cord morphogenesis and their application in neurodegenerative disease research. |
2025-01-28 |
2025-01-30 |
Not clear |
| Sandrine Bédard, Enamundram Naga Karthik, Charidimos Tsagkas, Emanuele Pravatà, Cristina Granziera, Andrew Smith, Kenneth Arnold Weber Ii, Julien Cohen-Ada. Towards contrast-agnostic soft segmentation of the spinal cord. Medical image analysis. vol 101. 2025-01-28. PMID:39874684. |
spinal cord segmentation is clinically relevant and is notably used to compute spinal cord cross-sectional area (csa) for the diagnosis and monitoring of cord compression or neurodegenerative diseases such as multiple sclerosis. |
2025-01-28 |
2025-01-31 |
human |
| Philip De Jager, Lu Zeng, Atlas Khan, Tsering Lama, Tanuja Chitnis, Howard Weiner, Gao Wang, Masashi Fujita, Frauke Zipp, Mariko Taga, Krzysztof Kirylu. GWAS highlights the neuronal contribution to multiple sclerosis susceptibility. Research square. 2025-01-27. PMID:39866869. |
multiple sclerosis (ms) is a chronic inflammatory and neurodegenerative disease affecting the brain and spinal cord. |
2025-01-27 |
2025-01-29 |
human |
| Fan Zhang, Jianping Hu, Zebin Xiao, Chenlin Lin, Zhuoting Huang, Ning Wang, Ying Li. Spinal cord cross sign: a potential marker for hereditary spastic paraplegia type 5. Neuroradiology. 2025-01-24. PMID:39853345. |
spastic paraplegia type 5 (spg5) is a rare neurodegenerative disease diagnosed primarily through genetic testing.we identified a specific spinal cord sign on conventional mr imaging to help narrow the scope of genetic screening. |
2025-01-24 |
2025-01-27 |
Not clear |
| Yang Yang, Yang Shao, Qi Dai, Yuxi Zhang, Yongxin Sun, Kunpeng Wang, Aihua X. Transcription factor AP-2 Beta, a potential target of repetitive Transspinal magnetic stimulation in spinal cord injury treatment, reduced inflammation and alleviated spinal cord injury. Experimental neurology. 2025-01-11. PMID:39798694. |
spinal cord injury (sci) is a neurodegenerative disease, with a high disability rate. |
2025-01-11 |
2025-01-16 |
rat |
| Kabirdas B Ghorpade, Shivanshu Agrawal, Ujwal Havelika. Biomarker Detection and Therapy of Parkinson's and Alzheimer's disease using upconversion based approach: A Comprehensive Review. Ageing research reviews. 2025-01-09. PMID:39788432. |
neurodegenerative diseases (nds) are debilitating disorders characterized by the progressive and selective loss of function or structure in the brain and spinal cord. |
2025-01-09 |
2025-01-13 |
Not clear |
| Jiaqi Li, Wenyi Xie, Jian-Min Chen, Chun-Zuan Xu, Ya-Li Huang, Sheng Chen, Chang-Yun Liu, Ying-Qian Lu, Zhang-Yu Zo. Clinical and functional characterization of a novel STUB1 mutation in a Chinese spinocerebellar ataxia 48 pedigree. Orphanet journal of rare diseases. vol 19. issue 1. 2024-12-21. PMID:39707479. |
spinocerebellar ataxias (scas) encompass a wide spectrum of inherited neurodegenerative diseases, primarily characterized by pathological changes in the cerebellum, spinal cord, and brainstem degeneration. |
2024-12-21 |
2024-12-24 |
Not clear |
| Lu Zeng, Khan Atlas, Tsering Lama, Tanuja Chitnis, Howard Weiner, Gao Wang, Masashi Fujita, Frauke Zipp, Mariko Taga, Krzysztof Kiryluk, Philip L De Jage. GWAS highlights the neuronal contribution to multiple sclerosis susceptibility. medRxiv : the preprint server for health sciences. 2024-12-16. PMID:39677438. |
multiple sclerosis (ms) is a chronic inflammatory and neurodegenerative disease affecting the brain and spinal cord. |
2024-12-16 |
2024-12-21 |
human |
| Zimeng Huang, Qing Liu, Qixuan Guo, Jianqing Gao, Luping Zhang, Liming L. Effects and mechanisms of Apelin in treating central nervous system diseases. Neuroscience. 2024-12-16. PMID:39681256. |
in this paper, we reviewed the effects and mechanisms of apelin in treating cns diseases, such as neurotrauma, stroke, spinal cord injury, primary tumors, neurodegenerative diseases, psychiatric diseases, epilepsy, and pain. |
2024-12-16 |
2024-12-21 |
Not clear |
| Jacques A Rousseau, Marcel Maier, Samia Ait-Mohand, Véronique Dumulon-Perreault, Otman Sarrhini, Sébastien Tremblay, Etienne Rousseau, Michael Salzmann, Brigitte Guéri. Antibody-Based PET Imaging of Misfolded Superoxide Dismutase 1 in an Amyotrophic Lateral Sclerosis Mouse Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024-12-12. PMID:39667814. |
amyotrophic lateral sclerosis (als) is a rare neurodegenerative disease characterized by motor neuron loss in the motor cortex, brain stem, and spinal cord. |
2024-12-12 |
2024-12-22 |
mouse |
| Hyo Jae Kim, Jae-Jun Ban, Junho Kang, Hye-Ryeong Im, Sun Hi Ko, Jung-Joon Sung, Sung-Hye Park, Jong-Eun Park, Seok-Jin Cho. Single-cell analysis reveals expanded CD8 Brain communications. vol 6. issue 6. 2024-12-11. PMID:39659975. |
single-cell analysis reveals expanded cd8 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that affects motor neurons in the brain and spinal cord. |
2024-12-11 |
2024-12-13 |
human |
| Chris W J van der Weijden, Ahmed K M A Ahmed, Anouk van der Hoorn, Junqing Zhu, Chunying Wu, Yanming Wang, Gilles N Stormezand, Rudi A J O Dierckx, Jan F Meilof, Erik F J de Vrie. Myelin Imaging of the Spinal Cord in Animal Models and Patients with Multiple Sclerosis Using [ Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024-12-05. PMID:39638431. |
myelin imaging of the spinal cord in animal models and patients with multiple sclerosis using [ multiple sclerosis (ms) is a neurodegenerative disease characterized by demyelinated lesions in the brain and spinal cord. |
2024-12-05 |
2024-12-08 |
Not clear |
| Mousumi Ghosh, Damien D Pears. The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases. Cells. vol 13. issue 22. 2024-11-27. PMID:39594583. |
under normal physiological conditions, mgevs are essential to homeostasis, whereas the dysregulation of their production and/or alterations in their cargoes have been implicated in the pathogenesis of numerous neurodegenerative diseases, including alzheimer's disease (ad), parkinson's disease (pd), multiple sclerosis (ms), spinal cord injury (sci), and traumatic brain injury (tbi). |
2024-11-27 |
2024-11-29 |
Not clear |
| Song Luo, Xiaorui Wang, Bo Ma, Dongliang Liu, Li Li, Lijin Wang, Ning Ding, Liangyu Zou, Jie Wang, Jialin Pan, Daoqian Sang, Huadong Zhou, Hongdang Qu, Yi Lu, Lijuan Yan. Therapeutic potential of Simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation. Biomolecules & biomedicine. 2024-11-21. PMID:39569650. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective death of motor neurons in the spinal cord, brainstem, and motor cortex. |
2024-11-21 |
2024-11-23 |
mouse |
| Patrick C Bradshaw, Jessa L Aldridge, Leah E Jamerson, Canah McNeal, A Catherine Pearson, Chad R Frasie. The Role of Cardiolipin in Brain Bioenergetics, Neuroinflammation, and Neurodegeneration. Molecular neurobiology. 2024-11-18. PMID:39557801. |
due to the high level of fatty acyl chain unsaturation, cl is prone to peroxidation during aging, neurodegenerative disease, stroke, and traumatic brain or spinal cord injury. |
2024-11-18 |
2024-11-22 |
Not clear |
| Carolina Sbarigia, Sophie Rome, Luciana Dini, Stefano Taccon. New perspectives of the role of skeletal muscle derived extracellular vesicles in the pathogenesis of amyotrophic lateral sclerosis: the 'dying back' hypothesis. Journal of extracellular biology. vol 3. issue 11. 2024-11-14. PMID:39534483. |
amyotrophic lateral sclerosis (als), is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord, and is characterized by muscle weakness, paralysis and ultimately, respiratory failure. |
2024-11-14 |
2024-11-17 |
Not clear |