Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Varsha Pai, Bhisham Narayan Singh, Abhishek Kumar Sing. Insights into Advances and Applications of Biomaterials for Nerve Tissue Injuries and Neurodegenerative Disorders. Macromolecular bioscience. 2024-09-30. PMID:39348168. |
the incidence of nerve tissue injuries, such as peripheral nerve injury, spinal cord injury, traumatic brain injury, and various neurodegenerative diseases (nds), is continuously increasing because of stress, physical and chemical trauma, and the aging population worldwide. |
2024-09-30 |
2024-10-02 |
Not clear |
Ali Shojaie, Ahmad Al Khleifat, Sarah Garrahy, Haniah Habash-Bailey, Rachel Thomson, Sarah Opie-Martin, Sara Javidnia, P Nigel Leigh, Ammar Al-Chalab. Investigating the impact of socioeconomic status on amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2024-09-01. PMID:39218010. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the gradual death of motor neurons in the brain and spinal cord, leading to fatal paralysis. |
2024-09-01 |
2024-09-04 |
human |
Shuang-Yin Lei, Yang Qu, Yu-Qian Yang, Jia-Cheng Liu, Yi-Fei Zhang, Sheng-Yu Zhou, Qian-Yan He, Hang Jin, Yi Yang, Zhen-Ni Gu. Cellular senescence: A novel therapeutic target for central nervous system diseases. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 179. 2024-08-25. PMID:39182322. |
in this study, we examined the relevant advancements in this field, particularly focusing on the targeting of senescent cells in the brain for the treatment of chronic neurodegenerative diseases (e.g., alzheimer's disease, parkinson's disease, and multiple sclerosis) and acute neurotraumatic insults (e.g., ischemic stroke, spinal cord injury, and traumatic brain injury). |
2024-08-25 |
2024-08-28 |
Not clear |
Zihao Liu, Huan Zhang, Kaili Lu, Li Chen, Yueqi Zhang, Zhouwei Xu, Hongsheng Zhou, Junfeng Sun, Mengyang Xu, Qi Ouyang, Garth J Thompson, Yi Yang, Ni Su, Xiaojun Cai, Li Cao, Yuwu Zhao, Lixian Jiang, Yuanyi Zheng, Xiaojie Zhan. Low-intensity pulsed ultrasound modulates disease progression in the SOD1 Cell reports. vol 43. issue 9. 2024-08-24. PMID:39180748. |
low-intensity pulsed ultrasound modulates disease progression in the sod1 amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord, and there are no effective drug treatments. |
2024-08-24 |
2024-08-27 |
Not clear |
Daniel Papp, Kyle M Gilbert, Gaspard Cereza, Alexandre D'Astous, Nibardo Lopez-Rios, Mathieu Boudreau, Marcus J Couch, Pedram Yazdanbakhsh, Robert L Barry, Eva Alonso-Ortiz, Julien Cohen-Ada. RF shimming in the cervical spinal cord at 7 T. Magnetic resonance in medicine. 2024-08-13. PMID:39136249. |
rf shimming in the cervical spinal cord at 7 t. advancing the development of 7 t mri for spinal cord imaging is crucial for the enhanced diagnosis and monitoring of various neurodegenerative diseases and traumas. |
2024-08-13 |
2024-08-16 |
Not clear |
Matteo Lusardi, Federica Rapetti, Andrea Spallarossa, Chiara Brull. PDE4D: A Multipurpose Pharmacological Target. International journal of molecular sciences. vol 25. issue 15. 2024-08-10. PMID:39125619. |
selective pde4d inhibitors (pde4dis) could represent an innovative and valid therapeutic strategy for the treatment of various neurodegenerative diseases, such as alzheimer's, parkinson's, huntington's, and lou gehrig's diseases, but also for stroke, traumatic brain and spinal cord injury, mild cognitive impairment, and all demyelinating diseases such as multiple sclerosis. |
2024-08-10 |
2024-08-13 |
Not clear |
Maria Guarnaccia, Giovanna Morello, Valentina La Cognata, Vincenzo La Bella, Francesca Luisa Conforti, Sebastiano Cavallar. Increased copy-number variant load of associated risk genes in sporadic cases of amyotrophic lateral sclerosis. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-07-28. PMID:39066921. |
amyotrophic lateral sclerosis (als) is an age-related neurodegenerative disease characterized by selective loss of motor neurons in the brainstem and spinal cord. |
2024-07-28 |
2024-08-02 |
Not clear |
Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Valeria Valsecchi, Giovanna Lombardi, Serenella Anzilotti, Giorgia Andreozzi, Antonia Scognamiglio, Rosa Sparaco, Elisa Perissutti, Beatrice Severino, Michele Gargiulo, Vincenzo Santagada, Giuseppe Pignatar. Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice. ACS pharmacology & translational science. vol 7. issue 7. 2024-07-18. PMID:39022351. |
the debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons (mns) in the brain, spinal cord, and motor cortex. |
2024-07-18 |
2024-07-20 |
mouse |
Halak Shukla, Diana John, Shuvomoy Banerjee, Anand Krishna Tiwar. Drug repurposing for neurodegenerative diseases. Progress in molecular biology and translational science. vol 207. 2024-06-28. PMID:38942541. |
neurodegenerative diseases (ndds) are neuronal problems that include the brain and spinal cord and result in loss of sensory and motor dysfunction. |
2024-06-28 |
2024-07-01 |
Not clear |
Elisabetta Carata, Marco Muci, Stefania Mariano, Simona Di Giulio, Annamaria Nigro, Alessandro Romano, Elisa Panzarin. Extracellular Vesicles from NSC-34 MN-like Cells Transfected with Mutant SOD1 Modulate Inflammatory Status of Raw 264.7 Macrophages. Genes. vol 15. issue 6. 2024-06-27. PMID:38927671. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease targeting the brain and spinal cord. |
2024-06-27 |
2024-06-29 |
Not clear |
Sylwia Dabrowska, Ermanna Turano, Ilaria Scambi, Federica Virla, Alice Nodari, Francesco Pezzini, Mirco Galiè, Bruno Bonetti, Raffaella Mariott. A Cellular Model of Amyotrophic Lateral Sclerosis to Study the Therapeutic Effects of Extracellular Vesicles from Adipose Mesenchymal Stem Cells on Microglial Activation. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891895. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive degeneration of upper and lower motor neurons (mns) in the brain and spinal cord, leading to progressive paralysis and death. |
2024-06-19 |
2024-06-21 |
human |
Hafiz Muhammad Husnain Azam, Rosa Ilse Rößling, Christiane Geithe, Muhammad Moman Khan, Franziska Dinter, Katja Hanack, Harald Prüß, Britta Husse, Dirk Roggenbuck, Peter Schierack, Stefan Rödige. MicroRNA biomarkers as next-generation diagnostic tools for neurodegenerative diseases: a comprehensive review. Frontiers in molecular neuroscience. vol 17. 2024-06-17. PMID:38883980. |
neurodegenerative diseases (nds) are characterized by abnormalities within neurons of the brain or spinal cord that gradually lose function, eventually leading to cell death. |
2024-06-17 |
2024-06-19 |
Not clear |
Emre Adıgüzel, Taha Gökmen Ülge. A marine-derived antioxidant astaxanthin as a potential neuroprotective and neurotherapeutic agent: A review of its efficacy on neurodegenerative conditions. European journal of pharmacology. 2024-06-06. PMID:38843946. |
in this systematic review, studies evaluating the efficacy of astaxanthin against different neurodegenerative diseases such as alzheimer's disease, parkinson's disease, multiple sclerosis, cerebrovascular diseases, and spinal cord injury are analyzed. |
2024-06-06 |
2024-06-10 |
Not clear |
Zihao Li, Ye Zhang, Meiling Ji, Chenglong Wu, Yanxing Zhang, Senlin J. Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 176. 2024-05-25. PMID:38795640. |
neurodegenerative diseases result from neuronal degeneration or demyelination in the brain or spinal cord, such as alzheimer's disease, parkinson's disease, huntington's disease, and amyotrophic lateral sclerosis. |
2024-05-25 |
2024-05-31 |
Not clear |
Pankaj Kadyan, Lovedeep Sing. Unraveling the mechanistic interplay of mediators orchestrating the neuroprotective potential of harmine. Pharmacological reports : PR. 2024-05-17. PMID:38758470. |
neurodegenerative diseases (ndds) encompass a range of conditions characterized by the specific dysfunction and continual decline of neurons, glial cells, and neural networks within the brain and spinal cord. |
2024-05-17 |
2024-05-27 |
Not clear |
Roberta Galli, Ortrud Uckerman. Vibrational spectroscopy and multiphoton microscopy for label-free visualization of nervous system degeneration and regeneration. Biophysical reviews. vol 16. issue 2. 2024-05-13. PMID:38737209. |
neurological disorders, including spinal cord injury, peripheral nerve injury, traumatic brain injury, and neurodegenerative diseases, pose significant challenges in terms of diagnosis, treatment, and understanding the underlying pathophysiological processes. |
2024-05-13 |
2024-05-27 |
Not clear |
Anas S Alyazidi, Osama Y Muthaffar, Layan S Baaishrah, Mohammed K Shawli, Abdulaziz T Jambi, Maram A Aljezani, Majdah A Almaghrab. Current Concepts in the Management of Sanfilippo Syndrome (MPS III): A Narrative Review. Cureus. vol 16. issue 4. 2024-05-13. PMID:38738088. |
sanfilippo syndrome is a childhood-onset (1-4 years) autosomal recessive lysosomal storage disease that presents as a neurodegenerative disease by targeting the brain and spinal cord. |
2024-05-13 |
2024-05-27 |
Not clear |
Faisal A Alzahrani, Yasir M Riza, Thamir M Eid, Reema Almotairi, Lea Scherschinski, Jessica Contreras, Muhammed Nadeem, Sylvia E Perez, Sudhanshu P Raikwar, Ruchira M Jha, Mark C Preul, Andrew F Ducruet, Michael T Lawton, Kanchan Bhatia, Naseem Akhter, Saif Ahma. Exosomes in Vascular/Neurological Disorders and the Road Ahead. Cells. vol 13. issue 8. 2024-04-26. PMID:38667285. |
neurodegenerative diseases, such as alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), huntington's disease (hd), stroke, and aneurysms, are characterized by the abnormal accumulation and aggregation of disease-causing proteins in the brain and spinal cord. |
2024-04-26 |
2024-04-28 |
Not clear |
Jiaying Shi, Zhaokun Wang, Ming Yi, Shengyu Xie, Xinyue Zhang, Dachang Tao, Yunqiang Liu, Yuan Yan. Evidence based on Mendelian randomization and colocalization analysis strengthens causal relationships between structural changes in specific brain regions and risk of amyotrophic lateral sclerosis. Frontiers in neuroscience. vol 18. 2024-03-20. PMID:38505770. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the degeneration of motor neurons in the brain and spinal cord with a poor prognosis. |
2024-03-20 |
2024-03-23 |
Not clear |
LiJun Zhou, RenShi X. Invertebrate genetic models of amyotrophic lateral sclerosis. Frontiers in molecular neuroscience. vol 17. 2024-03-19. PMID:38500677. |
amyotrophic lateral sclerosis (als) is a common adult-onset neurodegenerative disease characterized by the progressive death of motor neurons in the cerebral cortex, brain stem, and spinal cord. |
2024-03-19 |
2024-03-21 |
human |