| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Sampath, M Baska. Alzheimer's Disease Prediction Using Fly-Optimized Densely Connected Convolution Neural Networks Based on MRI Images. The journal of prevention of Alzheimer's disease. vol 11. issue 4. 2024-07-24. PMID:39044523. |
the progressive neurodegenerative disease known as alzheimer's disease (ad), affects the frontal cortex, the part of the brain in charge of memory, language, and cognition. |
2024-07-24 |
2024-07-26 |
Not clear |
| Yeon Kyeong Ko, Eunbi Kim, Eun-Jae Lee, Soo Jeong Nam, Yeshin Kim, Seongheon Kim, Se-Young Choi, Hyun Young Kim, Youngnim Cho. Enrichment of infection-associated bacteria in the low biomass brain bacteriota of Alzheimer's disease patients. PloS one. vol 19. issue 2. 2024-02-10. PMID:38335187. |
alzheimer's disease (ad) is a neurodegenerative disease accompanied by neuroimmune inflammation in the frontal cortex and hippocampus. |
2024-02-10 |
2024-02-12 |
human |
| John R Dickson, Matthew P Frosch, Bradley T Hyma. Altered localization of nucleoporin 98 in primary tauopathies. Brain communications. vol 5. issue 1. 2023-01-05. PMID:36601621. |
immunofluorescence staining was performed on frontal cortex and occipital cortex tissue from cases of primary tauopathies and controls without neurodegenerative disease using antibodies to identify nucleoporin 98, phospho-tau (ser202, thr205) monoclonal antibody and neuronal marker microtubule-associated protein 2. |
2023-01-05 |
2023-08-14 |
Not clear |
| Yarlagadda Anusha-Kiran, Praseeda Mol, Gourav Dey, Firdous Ahmad Bhat, Oishi Chatterjee, Sayali Chandrasekhar Deolankar, Mariamma Phillip, T S Keshava Prasad, M M Srinivas Bharath, Anita Mahadeva. Regional heterogeneity in mitochondrial function underlies region specific vulnerability in human brain ageing: Implications for neurodegeneration. Free radical biology & medicine. 2022-10-04. PMID:36195160. |
selective neuronal vulnerability (snv) of specific neuroanatomical regions such as frontal cortex (fc) and hippocampus (hc) is characteristic of age-associated neurodegenerative diseases (ndds), although its pathogenetic basis remains unresolved. |
2022-10-04 |
2023-08-14 |
human |
| Tomoko Miki, Osamu Yokota, Takashi Haraguchi, Hideki Ishizu, Masato Hasegawa, Takeshi Ishihara, Shu-Ichi Ueno, Shintaro Takenoshita, Seishi Terada, Norihito Yamad. Factors associated with development and distribution of granular/fuzzy astrocytes in neurodegenerative diseases. Brain pathology (Zurich, Switzerland). vol 30. issue 4. 2021-06-22. PMID:32293067. |
we immunohistochemically examined the frontal cortex, caudate nucleus, putamen and amygdala in 105 cases composed of argyrophilic grain disease cases (agd, n = 26), and progressive supranuclear palsy (psp, n = 10), alzheimer's disease (ad, n = 20) and primary age-related tauopathy cases (part, n = 18) lacking agd, as well as 31 cases bearing other various neurodegenerative diseases to clarify (i) the distribution patterns of gfas in agd, and psp, ad and part lacking agd, (ii) the impacts of major pathological factors and age on gfa formation and (iii) immunohistochemical features useful to understand the formation process of gfas. |
2021-06-22 |
2023-08-13 |
Not clear |
| Silvia Vanni, Marco Zattoni, Fabio Moda, Giorgio Giaccone, Fabrizio Tagliavini, Stéphane Haïk, Jean-Philippe Deslys, Gianluigi Zanusso, James W Ironside, Margarita Carmona, Isidre Ferrer, Gabor G Kovacs, Giuseppe Legnam. Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:29403351. |
hemoglobin mrna changes in the frontal cortex of patients with neurodegenerative diseases. |
2020-09-29 |
2023-08-13 |
Not clear |
| Roberta Andrejew, Ágatha Oliveira-Giacomelli, Deidiane Elisa Ribeiro, Talita Glaser, Vanessa Fernandes Arnaud-Sampaio, Claudiana Lameu, Henning Ulric. The P2X7 Receptor: Central Hub of Brain Diseases. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32848594. |
the p2x7 receptor is widely expressed in the cns, such as frontal cortex, hippocampus, amygdala and striatum, regions involved in neurodegenerative diseases and psychiatric disorders. |
2020-09-28 |
2023-08-13 |
Not clear |
| Verity J Brown, David S Tai. Attentional Set-Shifting Across Species. Current topics in behavioral neurosciences. vol 28. 2016-12-30. PMID:26873018. |
mediated by the frontal cortex in mammals, the cognitive processes involved in forming, maintaining and shifting an attentional set are vulnerable to dysfunction arising from a number of human neurodegenerative diseases (such as alzheimer's, parkinson's and huntington's diseases) and other neurological disorders (such as schizophrenia, depression, and attention deficit/hyperactivity disorder). |
2016-12-30 |
2023-08-13 |
human |
| Geidy E Serrano, Anthony Intorcia, Jeremiah Carew, Glenn Chiarolanza, Jose A Hidalgo, Lucia I Sue, Brittany N Dugger, Megan Saxon-LaBelle, Jessica Filon, Alex Scroggins, Joel Pullen, Brandon E Fornwalt, Sarah Scott, Marwan N Sabbagh, Charles H Adler, Haruhiko Akiyama, Thomas G Beac. Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases. Journal of neuropathology and experimental neurology. vol 74. issue 9. 2015-11-16. PMID:26230581. |
feasibility study: comparison of frontal cortex needle core versus open biopsy for detection of characteristic proteinopathies of neurodegenerative diseases. |
2015-11-16 |
2023-08-13 |
human |
| Geidy E Serrano, Anthony Intorcia, Jeremiah Carew, Glenn Chiarolanza, Jose A Hidalgo, Lucia I Sue, Brittany N Dugger, Megan Saxon-LaBelle, Jessica Filon, Alex Scroggins, Joel Pullen, Brandon E Fornwalt, Sarah Scott, Marwan N Sabbagh, Charles H Adler, Haruhiko Akiyama, Thomas G Beac. Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases. Journal of neuropathology and experimental neurology. vol 74. issue 9. 2015-11-16. PMID:26230581. |
here, we compared the ability of simulated needle core biopsy versus simulated open biopsy to detect the frontal cortex histopathology associated with common neurodegenerative diseases in the elderly using 144 autopsy-proven cases. |
2015-11-16 |
2023-08-13 |
human |
| Tania F Gendron, Kevin F Bieniek, Yong-Jie Zhang, Karen Jansen-West, Peter E A Ash, Thomas Caulfield, Lillian Daughrity, Judith H Dunmore, Monica Castanedes-Casey, Jeannie Chew, Danielle M Cosio, Marka van Blitterswijk, Wing C Lee, Rosa Rademakers, Kevin B Boylan, Dennis W Dickson, Leonard Petrucell. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS. Acta neuropathologica. vol 126. issue 6. 2014-07-10. PMID:24129584. |
of importance, foci composed of antisense transcripts are observed in the frontal cortex, spinal cord and cerebellum of c9ftd/als cases, and neuronal inclusions of poly(pr), poly(gp) and poly(pa) are present in various brain tissues in c9ftd/als, but not in other neurodegenerative diseases, including cag repeat disorders. |
2014-07-10 |
2023-08-12 |
human |
| J Blin, B Horwitz, J C Baron, Y Agi. Does frontal cortex hypometabolism in progressive supranuclear palsy result from subcortical dysfunction? European journal of neurology. vol 1. issue 3. 2013-12-03. PMID:24283522. |
progressive supranuclear palsy (psp), a neurodegenerative disease with frontal lobe-like features, shows brain hypometabolism which predominates in frontal cortex, although the most severe histopathological lesions are subcortical. |
2013-12-03 |
2023-08-12 |
Not clear |
| Catherine Chapados, Michael Petride. Impairment only on the fluency subtest of the Frontal Assessment Battery after prefrontal lesions. Brain : a journal of neurology. vol 136. issue Pt 10. 2013-11-25. PMID:24030949. |
performance on the frontal assessment battery has been shown to be sensitive to various neurodegenerative diseases, but it has never been shown to be sensitive to damage restricted to the frontal cortex. |
2013-11-25 |
2023-08-12 |
Not clear |
| Li Zhou, Eve Diefenbach, Ben Crossett, Sieu L Tran, Thomas Ng, Helen Rizos, Rejane Rua, Bin Wang, Amit Kapur, Kaushal Gandhi, Bruce J Brew, Nitin K Saksen. First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia. Molecular neurodegeneration. vol 5. 2011-07-14. PMID:20573273. |
first evidence of overlaps between hiv-associated dementia (had) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from hiv+ patients with and without dementia. |
2011-07-14 |
2023-08-12 |
Not clear |
| Jon Zárate, Encarnación Goicoechea, Jesús Pascual, Enrique Echevarría, Mariá D Guillé. A study of the toxic effect of oxidized sunflower oil containing 4-hydroperoxy-2-nonenal and 4-hydroxy-2-nonenal on cortical TrkA receptor expression in rats. Nutritional neuroscience. vol 12. issue 6. 2010-02-24. PMID:19925718. |
these results indicate that toxic substances present in the oxidized sunflower oil, among them 4-hydroxy-trans-2-nonenal (hne) and 4-hydroperoxy-trans-2-nonenal (hpne), could disrupt survival signalling of frontal cortex cholinergic neurons, which could lead to apoptosis and neurodegenerative diseases. |
2010-02-24 |
2023-08-12 |
rat |
| Ana Navarro, Alberto Boveris, Manuel J Bández, María Jesús Sánchez-Pino, Carmen Gómez, Gerard Muntané, Isidro Ferre. Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies. Free radical biology & medicine. vol 46. issue 12. 2009-09-17. PMID:19298851. |
the adaptive response would partially compensate for mitochondrial dysfunction in these neurodegenerative diseases and would afford a human evolutionary response to shortage of atp in the frontal cortex. |
2009-09-17 |
2023-08-12 |
human |
| Kimmo J Hatanpaa, Eileen H Bigio, Nigel J Cairns, Kyle B Womack, Sandra Weintraub, John C Morris, Chan Foong, Guanghua Xiao, Christa Hladik, Tina Y Mantanona, Charles L Whit. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. Journal of neuropathology and experimental neurology. vol 67. issue 4. 2008-06-12. PMID:18379440. |
we studied tdp-43 pathology in the hippocampus and frontal cortex of autopsy brains from patients with ftld-u (n = 68), dementia lacking distinctive histopathology (n = 4), other neurodegenerative diseases (n = 23), and controls (n = 12) using a sensitive immunohistochemistry protocol. |
2008-06-12 |
2023-08-12 |
Not clear |
| Kimmo J Hatanpaa, Eileen H Bigio, Nigel J Cairns, Kyle B Womack, Sandra Weintraub, John C Morris, Chan Foong, Guanghua Xiao, Christa Hladik, Tina Y Mantanona, Charles L Whit. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. Journal of neuropathology and experimental neurology. vol 67. issue 4. 2008-06-12. PMID:18379440. |
of the cases with other neurodegenerative diseases, 43% showed tdp-43 pathology in the hippocampus, but only 4% showed tdp-43 pathology in the frontal cortex. |
2008-06-12 |
2023-08-12 |
Not clear |
| G Santpere, B Puig, I Ferre. Oxidative damage of 14-3-3 zeta and gamma isoforms in Alzheimer's disease and cerebral amyloid angiopathy. Neuroscience. vol 146. issue 4. 2007-10-25. PMID:17445990. |
the present study shows glycoxidative damage, as revealed with mono and bi-dimensional gel electrophoresis and western blotting, followed by in-gel digestion and mass spectrometry, in the frontal cortex in alzheimer's disease (ad) and cerebral amyloid angiopathy (caa), a neurodegenerative disease with deposition of abeta in cerebral blood vessels and in diffuse plaques unaccompanied by intraneuronal hyper-phosphorylated tau deposition. |
2007-10-25 |
2023-08-12 |
Not clear |
| Esther Dalfó, José Luis Albasanz, Agustín Rodríguez, Mairena Martín, Isidro Ferre. Abnormal group I metabotropic glutamate receptor expression and signaling in the frontal cortex in Pick disease. Journal of neuropathology and experimental neurology. vol 64. issue 7. 2005-08-11. PMID:16042316. |
the present work examines mgluri expression and signaling in the frontal cortex (area 8) of 3 cases with pick disease (pid), a neurodegenerative disease with abnormal phospho-tau accumulation, in comparison with 3 age-matched controls by means of glutamate binding assays, enzymatic activity, gel electrophoresis and western blotting, solubility and immunoprecipitation assays, and confocal microscopy. |
2005-08-11 |
2023-08-12 |
Not clear |