| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohannad O Khrieba, Sahar K Hegazy, Wessam Fathi Mohammed, Sahar M El-Hagga. Clinical study to investigate the adjuvant role of Pentoxifylline in patients with Parkinson's disease: A randomized controlled study. International immunopharmacology. vol 156. 2025-04-20. PMID:40253769. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by the loss of dopaminergic neurons in the par's compacta of the substantia nigra. |
2025-04-20 |
2025-04-23 |
Not clear |
| Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yan. A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals. Advanced healthcare materials. 2025-04-08. PMID:40195900. |
parkinson's disease (pd), one of the most common neurodegenerative diseases, is involved in motor abnormality, primarily arising from the degeneration of dopaminergic neurons. |
2025-04-08 |
2025-04-10 |
Not clear |
| Eman Allam, Sary Khalil Abdel Ghafar, Manal Hussein, Ahmed Al-Emam, Khaled Rada. Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson's Disease Rat Model Challenged with Rotenone. CNS & neurological disorders drug targets. 2025-03-21. PMID:40114566. |
parkinson's disease, the second most common neurodegenerative disease, is still lacking an effective treatment that can stop dopaminergic cell loss in substantia nigra and alter disease progression. |
2025-03-21 |
2025-03-23 |
rat |
| Sanghoon Kim, Edward Pajarillo, Alexis Digman, Itunu Ajayi, Deok-Soo Son, Michael Aschner, Eunsook Le. Role of dopaminergic RE1-silencing transcription factor (REST) in manganese-induced behavioral deficits and dysregulating dopaminergic and serotonergic neurotransmission in mice. Neurotoxicology. 2025-03-08. PMID:40057281. |
mn is well known to dysregulate dopaminergic (daergic) function, and the repressor element-1 silencing transcription factor (rest) induces protection against mn-induced toxicity and several neurodegenerative diseases, including pd and alzheimer's disease. |
2025-03-08 |
2025-03-12 |
mouse |
| Lijun Dai, Jiannan Wang, Lanxia Meng, Xingyu Zhang, Tingting Xiao, Min Deng, Guiqin Chen, Jing Xiong, Wei Ke, Zhengyuan Hong, Lihong Bu, Zhentao Zhan. The cholesterol 24-hydroxylase CYP46A1 promotes α-synuclein pathology in Parkinson's disease. PLoS biology. vol 23. issue 2. 2025-02-18. PMID:39964974. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the death of dopaminergic neurons in the substantia nigra and the formation of lewy bodies that are composed of aggregated α-synuclein (α-syn). |
2025-02-18 |
2025-02-23 |
mouse |
| Virendra Kumar Yadav, Seshathiri Dhanasekaran, Nisha Choudhary, Deepak Nathiya, Vishal Thakur, Rachna Gupta, Sheersha Pramanik, Pankaj Kumar, Nishant Gupta, Ashish Pate. Recent advances in nanotechnology for Parkinson's disease: diagnosis, treatment, and future perspectives. Frontiers in medicine. vol 12. 2025-02-06. PMID:39911864. |
parkinson's disease is a progressive neurodegenerative disease that destroys substantia nigra dopaminergic neurons, causing tremors, bradykinesia, rigidity, and postural instability. |
2025-02-06 |
2025-02-08 |
Not clear |
| Raelynn Brassard, Elena Arutyunova, Emmanuella Takyi, L Michel Espinoza-Fonseca, Howard Young, Nicolas Touret, M Joanne Lemieu. Transmembrane Parkinson's Disease mutation of PINK1 leads to altered mitochondrial anchoring. The Journal of biological chemistry. 2025-02-05. PMID:39909370. |
parkinson's disease (pd) is a devastating neurodegenerative disease resulting from the death of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. |
2025-02-05 |
2025-02-08 |
Not clear |
| Wenjie Qin, Ruiqi Su, Xiaodie Chen, Zhiyan Liang, Linyan Huang, Xuhong Qian, Youjun Yang, Suhua Qi, Xiao Lu. Synergistic Anti-Ferroptosis with a Minimalistic, Peroxide-Triggered Carbon Monoxide Donor for Parkinson's Disease. Journal of medicinal chemistry. 2025-02-03. PMID:39895106. |
parkinson's disease (pd) is a debilitating neurodegenerative disease, with current treatments primarily focusing on improving dopaminergic activity, providing symptomatic relief but failing to halt disease progression. |
2025-02-03 |
2025-02-05 |
Not clear |
| Jin-Yu Liang, Xiao-Lei Yuan, Jia-Mei Jiang, Ping Zhang, Kuang-Ta. Targeting the NLRP3 inflammasome in Parkinson's disease: From molecular mechanism to therapeutic strategy. Experimental neurology. 2025-01-30. PMID:39884329. |
parkinson's disease is the second most common neurodegenerative disease, characterized by substantial loss of dopaminergic (da) neurons, the formation of lewy bodies (lbs) in the substantia nigra, and pronounced neuroinflammation. |
2025-01-30 |
2025-02-02 |
Not clear |
| Julia C Fitzgerald, Ying Sun, Frederek Reinecke, Elisabeth Bauer, Olga Garaschuk, Philipp J Kahle, Friederike Pfeiffe. Interactions of Oligodendrocyte Precursor Cells and Dopaminergic Neurons in the Mouse Substantia Nigra. Journal of neurochemistry. vol 169. issue 1. 2025-01-28. PMID:39871627. |
parkinson's disease (pd) is a prevalent neurodegenerative disease caused by the death of dopaminergic neurons within the substantia nigra pars compacta (snpc) region of the midbrain. |
2025-01-28 |
2025-01-30 |
mouse |
| Rong Sha, Mingzhe Wu, Pengfei Wang, Ziyuan Chen, Wei Lei, Shimiao Wang, Shun Gong, Guobiao Liang, Rui Zhao, Yingqun Ta. Adolescent mice exposed to TBI developed PD-like pathology in middle age. Translational psychiatry. vol 15. issue 1. 2025-01-25. PMID:39863574. |
traumatic brain injury (tbi) is identified as a risk factor for parkinson's disease (pd), which is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra (sn). |
2025-01-25 |
2025-01-28 |
mouse |
| Edward F Griffin, Madeline G Owen. Dopaminergic neurodegeneration in microPublication biology. vol 2025. 2025-01-22. PMID:39839711. |
dopaminergic neurodegeneration in disruption of the human microbiome has emerged as a major contributing factor in the etiology of neurodegenerative disease. |
2025-01-22 |
2025-01-24 |
human |
| Joana Sobral, Nuno Empadinhas, Ana Raquel Esteves, Sandra Morais Cardos. Impact of Nutrition on the Gut Microbiota: Implications for Parkinson's Disease. Nutrition reviews. 2025-01-15. PMID:39812804. |
parkinson's disease (pd) is a multifactorial neurodegenerative disease that is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta and by the anomalous accumulation of α-synuclein aggregates into lewy bodies and lewy neurites. |
2025-01-15 |
2025-01-17 |
human |
| Duanqin Guan, Congmin Liang, Dongyan Zheng, Shizhen Liu, Jiankun Luo, Ziwei Cai, He Zhang, Jialong Che. The role of mitochondrial remodeling in neurodegenerative diseases. Neurochemistry international. 2025-01-11. PMID:39798853. |
pathological changes in mitochondrial function and morphology, as well as interactions with other organelles, can affect the energy metabolism of dopaminergic neurons and participate in the development of neurodegenerative diseases. |
2025-01-11 |
2025-01-16 |
human |
| Nandita Ravichandran, Mahalaxmi Iyer, Deenathayalan Uvarajan, Laxmi Kirola, Sindduja Muthu Kumra, Harysh Winster Suresh Babu, Dibbanti HariKrishnaReddy, Balachandar Vellingiri, Arul Narayanasam. New insights on the regulators and inhibitors of RhoA-ROCK signalling in Parkinson's disease. Metabolic brain disease. vol 40. issue 1. 2025-01-08. PMID:39775342. |
a multifaceted and widely prevalent neurodegenerative disease, parkinson's disease (pd) is typified by the loss of dopaminergic neurons in the midbrain. |
2025-01-08 |
2025-01-13 |
Not clear |
| José María Salazar Campos, Lena F Burbulla, Sarah Jäke. Are oligodendrocytes bystanders or drivers of Parkinson's disease pathology? PLoS biology. vol 23. issue 1. 2025-01-08. PMID:39777410. |
the major pathological feature of parkinson 's disease (pd), the second most common neurodegenerative disease and most common movement disorder, is the predominant degeneration of dopaminergic neurons in the substantia nigra, a part of the midbrain. |
2025-01-08 |
2025-01-13 |
Not clear |
| Shufen Liu, Tingting Liu, Jingwen Li, Jun Hong, Ali A Moosavi-Movahedi, Jianshe We. Type 2 Diabetes Mellitus Exacerbates Pathological Processes of Parkinson's Disease: Insights from Signaling Pathways Mediated by Insulin Receptors. Neuroscience bulletin. 2025-01-04. PMID:39754628. |
parkinson's disease (pd), a chronic and common neurodegenerative disease, is characterized by the progressive loss of dopaminergic neurons in the dense part of the substantia nigra and abnormal aggregation of alpha-synuclein. |
2025-01-04 |
2025-01-08 |
Not clear |
| Liang Wang, Yuan Yao, Bojun Xie, Ming Lei, Yiwei Li, Jiaming Shi, Liyang Yu, Wenjuan Zhou, Yuanhua Sang, Liang Kong, Hong Liu, Jichuan Qi. Nanoelectrode-Mediated Extracellular Electrical Stimulation Directing Dopaminergic Neuronal Differentiation of Stem Cells for Improved Parkinson's Disease Therapy. Advanced materials (Deerfield Beach, Fla.). 2024-12-20. PMID:39703114. |
parkinson's disease (pd) is a neurodegenerative disease caused by the dysfunction and death of dopaminergic neurons. |
2024-12-20 |
2024-12-22 |
mouse |
| Jin Hee Kim, Eugene Huh, Hyeyoon Eo, Jin Se Kim, Youngji Kwon, In Gyoung Ju, Yujin Choi, Hae-Jee Yoon, So-Ri Son, Dae Sik Jang, Seon-Pyo Hong, Hi-Joon Park, Myung Sook O. Tribuli Fructus alleviates 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease by suppressing neuroinflammation via JNK signaling. Metabolic brain disease. vol 40. issue 1. 2024-12-19. PMID:39699803. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons. |
2024-12-19 |
2024-12-21 |
mouse |
| Sa Weon Hong, Rachel Page, Penelope Truma. Smoking, coffee intake, and Parkinson's disease: potential protective mechanisms and components. Neurotoxicology. 2024-12-19. PMID:39701424. |
parkinson's disease (pd) is a common progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2024-12-19 |
2024-12-22 |
Not clear |