| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang Ao, Guoqiang Ji, Bingqiang Zhang, Wei Ding, Jianxun Wang, Ying Liu, Junqiang Xu. Role of apoptosis repressor with caspase recruitment domain in human health and chronic diseases. Annals of medicine. vol 56. issue 1. 2024-10-01. PMID:39351758. |
arc dysregulation has been shown to be closely associated with many chronic diseases, including cardiovascular disease, cancer, diabetes, and neurodegenerative disease. |
2024-10-01 |
2024-10-03 |
human |
| Idris A Azeez, Ifeoluwa O Awogbindin, Juliet N Olayinka, Royhaan O Folarin, Abubakar S Adamu, Lydia D Ior, Asmau M Shehu, Abubakar I Mukhtar, Olufunke F Ajeigbe, Aghariagbonse O Emokpae, Ifukibot L Usende, Bamidele R Babatunde, Yusuf Yusha'u, Oladiran I Olateju, Ronald Kamoga, Ayoola I O Benson, Kenneth C Oparaji, Idowu O Owemidu, Musa O Iliyasu, Maryam I Imam, James O Olopad. Neural stem cell research in Africa: current realities and future prospects. Biology open. vol 11. issue 11. 2022-11-03. PMID:36326097. |
the international brain research organization (ibro)-african regional committee (arc), with support from the company of biologists, and the movement disorder society, sponsored the first african basic school on nsc in ibadan, nigeria, with the vision of bringing together young neuroscientists and physicians across different fields in neuroscience to learn from leaders who have applied nscs in stem cell research, the pathophysiology of neurodegenerative diseases, neuroanatomy, and neurotherapeutics. |
2022-11-03 |
2023-08-14 |
human |
| Yuchun Liu, Yao Sun, Yonghui Huang, Kang Cheng, Yuming Xu, Qingnan Tian, Shoutao Zhan. CHIP promotes Wnt signaling and regulates Arc stability by recruiting and polyubiquitinating LEF1 or Arc. Cell death discovery. vol 7. issue 1. 2021-01-22. PMID:33431799. |
previous studies have shown that wnt signaling and activity-regulated cytoskeleton-associated protein (arc) play important roles in neurodegenerative diseases. |
2021-01-22 |
2023-08-13 |
rat |
| Laura Mateos, Susanne Akterin, Francisco-Javier Gil-Bea, Stefan Spulber, Atiqur Rahman, Ingemar Björkhem, Marianne Schultzberg, Amilcar Flores-Morales, Angel Cedazo-Míngue. Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro. Brain pathology (Zurich, Switzerland). vol 19. issue 1. 2009-02-19. PMID:18503570. |
we propose that one of the mechanisms, by which hypercholesterolemia contributes to neurodegenerative diseases, could be through arc down-regulation caused by 27-hydroxycholesterol. |
2009-02-19 |
2023-08-12 |
mouse |