| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jinping Liang, Yuchen Zhu, Shasha Liu, Boyu Kuang, Zhifeng Tian, Ling Zhang, Songwei Yang, Meiyu Lin, Naihong Chen, Xuan Liu, Qidi Ai, Yantao Yan. Progress of Exosomal MicroRNAs and Traditional Chinese Medicine Monomers in Neurodegenerative Diseases. Phytotherapy research : PTR. 2024-09-03. PMID:39225243. |
notably, tcm monomers, serving as active constituents within herbal medicine, assume a critical role in the treatment of neurodegenerative diseases, particularly in mitigating oxidative stress, inhibiting apoptosis, and reducing inflammation. |
2024-09-03 |
2024-09-05 |
Not clear |
| Ya-Xi Ye, Jian-Cheng Pan, Hai-Chao Wang, Xing-Tao Zhang, Hai-Liang Zhu, Xin-Hua Li. Advances in small-molecule fluorescent probes for the study of apoptosis. Chemical Society reviews. 2024-08-12. PMID:39129564. |
mounting research indicates that the unique modality of cell apoptosis is directly or indirectly related to different diseases including cancer, autoimmune diseases, viral diseases, neurodegenerative diseases, |
2024-08-12 |
2024-08-14 |
Not clear |
| Eui-Hwan Choi, Mi-Hye Kim, Sun-Ji Par. Targeting Mitochondrial Dysfunction and Reactive Oxygen Species for Neurodegenerative Disease Treatment. International journal of molecular sciences. vol 25. issue 14. 2024-07-27. PMID:39063194. |
in this review, we provide an overview of the main functions of mitochondria, with a focus on recent progress highlighting the critical role of ros-induced oxidative stress, dysregulated mitochondrial dynamics, mitochondrial apoptosis, mitochondria-associated inflammation, and impaired mitochondrial function in the pathogenesis of age-related neurodegenerative diseases, such as ad and pd. |
2024-07-27 |
2024-07-29 |
Not clear |
| Mateusz Kciuk, Nitika Garg, Sanchit Dhankhar, Monika Saini, Somdutt Mujwar, Sushma Devi, Samrat Chauhan, Thakur Gurjeet Singh, Randhir Singh, Beata Marciniak, Adrianna Gielecińska, Renata Konte. Exploring the Comprehensive Neuroprotective and Anticancer Potential of Afzelin. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931368. |
both cancer and neurodegenerative diseases involve the deregulation of cellular processes such as apoptosis, proliferation, and dna repair and pose a significant global health challenge. |
2024-06-27 |
2024-06-29 |
Not clear |
| Xiaoqing Peng, Yuanyuan Yang, Ruirui Hou, Longbiao Zhang, Can Shen, Xiaoyan Yang, Zhigang Luo, Zongzhi Yin, Yunxia Ca. MTCH2 in Metabolic Diseases, Neurodegenerative Diseases, Cancers, Embryonic Development and Reproduction. Drug design, development and therapy. vol 18. 2024-06-17. PMID:38882047. |
recent studies revealed the physiological and pathological function of mtch2 in metabolic diseases, neurodegenerative diseases, cancers, embryonic development and reproduction via regulating mitochondrial apoptosis, metabolic shift between glycolysis and oxidative phosphorylation, mitochondrial fusion/fission, epithelial-mesenchymal transition, etc. |
2024-06-17 |
2024-06-19 |
Not clear |
| Ning Zhao, Junyi Wang, Shan Huang, Jingyu Zhang, Jin Bao, Haisen Ni, Xinhang Gao, Chunlong Zhan. The landscape of programmed cell death-related lncRNAs in Alzheimer's disease and Parkinson's disease. Apoptosis : an international journal on programmed cell death. 2024-06-09. PMID:38853201. |
we propose a new framework pcdlnc, and identified 20 significant lncrnas, including heih, snhg15, and snhg5, associated with pcd gene sets, which were known for roles in proliferation and apoptosis in neurodegenerative diseases. |
2024-06-09 |
2024-06-14 |
Not clear |
| Yong Yao, Yaping Yuan, Shuyan Sheng, Yifan Li, Xiaoniu Tang, Hao G. Observing astrocyte polarization in brains from mouse chronically infected with Toxoplasma gondii. Scientific reports. vol 14. issue 1. 2024-05-07. PMID:38714696. |
astrocyte polarization, particularly the a1 subtype associated with neuronal apoptosis, has been identified in various neurodegenerative diseases. |
2024-05-07 |
2024-05-27 |
mouse |
| Shuang Zhao, Guiling Mo, Qiang Wang, Jin Xu, Shihui Yu, Zhibin Huang, Wei Liu, Wenqing Zhan. Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b. Cell death discovery. vol 10. issue 1. 2024-04-18. PMID:38637503. |
role of rb1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via kmt5b. |
2024-04-18 |
2024-04-21 |
human |
| Shuang Zhao, Guiling Mo, Qiang Wang, Jin Xu, Shihui Yu, Zhibin Huang, Wei Liu, Wenqing Zhan. Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b. Cell death discovery. vol 10. issue 1. 2024-04-18. PMID:38637503. |
dysregulation of neuronal apoptosis can lead to neurodegenerative diseases. |
2024-04-18 |
2024-04-21 |
human |
| Hidenori Homma, Hikari Tanaka, Kyota Fujita, Hitoshi Okazaw. Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612448. |
apoptosis was previously considered to be the only mechanism of neuronal cell death in neurodegenerative diseases. |
2024-04-13 |
2024-04-15 |
Not clear |
| Linnet Bischof, Franziska Schweitzer, Jürgen J Heinisc. Functional Conservation of the Small GTPase Rho5/Rac1-A Tale of Yeast and Men. Cells. vol 13. issue 6. 2024-03-27. PMID:38534316. |
malfunctions in this context affect cellular plasticity and apoptosis, related to neurodegenerative diseases and diabetes. |
2024-03-27 |
2024-03-29 |
human |
| Mohamed J Saadh, Ahmed Faisal, Mohaned Adil, Rahman S Zabibah, Abdurakhmon Mamatkulovich Mamadaliev, Mahmood Jasem Jawad, Fahad Alsaikhan, Bagher Farhoo. Parkinson's Disease and MicroRNAs: A Duel Between Inhibition and Stimulation of Apoptosis in Neuronal Cells. Molecular neurobiology. 2024-03-23. PMID:38520611. |
in that context, targeting apoptosis appears as a promising therapeutic approach for treating neurodegenerative diseases. |
2024-03-23 |
2024-03-26 |
Not clear |
| Mohamed J Saadh, Ahmed Faisal, Mohaned Adil, Rahman S Zabibah, Abdurakhmon Mamatkulovich Mamadaliev, Mahmood Jasem Jawad, Fahad Alsaikhan, Bagher Farhoo. Parkinson's Disease and MicroRNAs: A Duel Between Inhibition and Stimulation of Apoptosis in Neuronal Cells. Molecular neurobiology. 2024-03-23. PMID:38520611. |
non-coding rnas-more especially, micrornas, or mirnas-are a promising target for the therapy of neurodegenerative diseases because they are essential for a number of cellular processes, including signaling, apoptosis, cell proliferation, and gene regulation. |
2024-03-23 |
2024-03-26 |
Not clear |
| Evgenii D Kryl'skii, Grigorii A Razuvaev, Tatyana N Popova, Sergei A Oleinik, Svetlana M Medvedeva, Khidmet S Shikhalie. 6-Hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline Demonstrates Neuroprotective Properties in Experimental Parkinson's Disease by Enhancing the Antioxidant System, Normalising Chaperone Activity and Suppressing Apoptosis. Neurochemical research. 2024-03-19. PMID:38502411. |
parkinson's disease (pd) is a neurodegenerative disease, whereby disturbances within the antioxidant defence system, increased aggregation of proteins, and activation of neuronal apoptosis all have a crucial role in the pathogenesis. |
2024-03-19 |
2024-03-23 |
rat |
| Siva Prasad Panda, Adarsh Kesharwani, Samaresh Datta, D S N B K Prasanth, Sunil Kumar Panda, Ajay Gur. JAK2/STAT3 as a new potential target to manage neurodegenerative diseases: An interactive review. European journal of pharmacology. 2024-03-16. PMID:38492876. |
neurodegenerative diseases (ndds) are a collection of incapacitating disorders in which neuroinflammation and neuronal apoptosis are major pathological consequences due to oxidative stress. |
2024-03-16 |
2024-03-19 |
human |
| Beatrice Silvestri, Michela Mochi, Darilang Mawrie, Valeria de Turris, Alessio Colantoni, Beatrice Borhy, Margherita Medici, Eric Nathaniel Anderson, Maria Giovanna Garone, Christopher Patrick Zammerilla, Udai Bhan Pandey, Alessandro Ros. HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in bioRxiv : the preprint server for biology. 2024-03-11. PMID:38464028. |
hud (elavl4) gain-of-function impairs neuromuscular junctions and induces apoptosis in early defects at the neuromuscular junction (nmj) are among the first hallmarks of the progressive neurodegenerative disease amyotrophic lateral sclerosis (als). |
2024-03-11 |
2024-03-14 |
Not clear |
| Huiyong Zheng, Qiang Liu, Siwei Zhou, Hongliang Luo, Wenjun Zhan. Role and therapeutic targets of P2X7 receptors in neurodegenerative diseases. Frontiers in immunology. vol 15. 2024-02-19. PMID:38370420. |
when neurodegenerative diseases result in neuronal apoptosis and necrosis, atp activates the p2x7r. |
2024-02-19 |
2024-02-21 |
Not clear |
| Hamidreza Poortalebi, Mahta ZareDini, Sima Foroughi-Nematollahi, Tahereh Farkhondeh, Saeed Samarghandian, Mohammad Hossein Pourhanife. Therapeutic Effect of Resveratrol and its Novel Formulations on Lung Cancer: Focus on Biological Aspects and Underlying Pathways. Current medicinal chemistry. 2024-02-02. PMID:38303533. |
it has shown therapeutic potetial in various diseases including neurodegenerative diseases, cardiovascular disorders, and cancers through the regulation of key cellular signaling such as apoptosis, as well as molecular pathways such as microrna modulation. |
2024-02-02 |
2024-02-04 |
Not clear |
| Sahar Golpour- Hamedani, Makan Pourmasoumi, Sudiyeh Hejri Zarifi, Gholamreza Askari, Tannaz Jamialahmadi, Mohammad Bagherniya, Amirhossein Sahebka. Therapeutic effects of saffron and its components on neurodegenerative diseases. Heliyon. vol 10. issue 2. 2024-02-01. PMID:38298664. |
saffron and its compounds can play an important role in inhibiting neuroinflammation and excitotoxic pathways, modulating autophagy and apoptosis, attenuating oxidative damage, and activating defensive antioxidant enzymes, resulting in neuroprotection against neurodegenerative diseases. |
2024-02-01 |
2024-02-03 |
human |
| Kohei Sone, Asami Mori, Kenji Sakamoto, Tsutomu Nakahar. The Role of microRNAs Related to Apoptosis for International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256177. |
apoptosis is one of the common mechanisms leading to neuronal death in many neurodegenerative diseases, including glaucoma. |
2024-01-23 |
2024-01-25 |
Not clear |