All Relations between Neurodegenerative Diseases and Tauopathies

Publication Sentence Publish Date Extraction Date Species
Sebastian N Roemer, Matthias Brendel, Johannes Gnoerich, Maura Malpetti, Mirlind Zaganjori, Andrea Quattrone, Mattes Gross, Anna Steward, Anna Dewenter, Fabian Wagner, Amir Dehsarvi, Christian Ferschmann, Stephan Wall, Carla Palleis, Boris S Rauchmann, Sabrina Katzdobler, Alexander Jaeck, Anna Stockbauer, Urban M Fietzek, Alexander M Bernhardt, Endy Weidinger, Andreas Zwergal, Sophia Stoecklein, Robert Perneczky, Henryk Barthel, Osama Sabri, Johannes Levin, Guenter U Hoeglinger, Nicolai Franzmeie. Subcortical tau is linked to hypoperfusion in connected cortical regions in 4-repeat tauopathies. Brain : a journal of neurology. 2024-06-06. PMID:38842726. 4-repeat (4r) tauopathies are neurodegenerative diseases characterized by cerebral accumulation of 4r tau pathology. 2024-06-06 2024-06-08 Not clear
Itzhak Fischer, Theresa Connors, Julien Bouyer, Ying Ji. The unique properties of Big tau in the visual system. Cytoskeleton (Hoboken, N.J.). 2024-05-18. PMID:38761116. tau is a microtubule associated protein that plays important roles in regulating the properties of microtubules and axonal transport, as well as tauopathies associated with toxic aggregates leading to neurodegenerative diseases. 2024-05-18 2024-05-27 rat
Chenxi Qiu, Zhixiong Li, David A Leigh, Bingbing Duan, Joseph E Stucky, Nami Kim, George Xie, Kun Ping Lu, Xiao Zhen Zho. The role of the Pin1- Frontiers in cell and developmental biology. vol 12. 2024-04-17. PMID:38628595. the role of the pin1- tauopathies are neurodegenerative diseases characterized by deposits of abnormal tau protein in the brain. 2024-04-17 2024-04-19 Not clear
Parissa Fereydouni-Forouzandeh, Geoffrey Canet, Sofia Diego-Diàz, Emma Rocaboy, Serena Petry, Robert A Whittington, Emmanuel Plane. Western Blot of Tau Protein from Mouse Brains Extracts: How to Avoid Signal Artifacts. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512673. in alzheimer's disease and other neurodegenerative diseases known as tauopathies, tau undergoes several abnormal post-translational modifications including hyperphosphorylation, conformational changes, oligomerization, and aggregation. 2024-03-21 2024-03-24 mouse
Léa El Hajjar, Clarisse Bridot, Marine Nguyen, François-Xavier Cantrelle, Isabelle Landrieu, Caroline Smet-Nocc. Phosphorylation of Tau Protein by CDK2/cyclin A and GSK3β Recombinant Kinases: Analysis of Phosphorylation Patterns by Nuclear Magnetic Resonance Spectroscopy. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512672. under its aggregated form, tau is a hallmark of alzheimer's disease and other neurodegenerative diseases named tauopathies involving tau dysfunction and/or mutations. 2024-03-21 2024-03-24 Not clear
Geoffrey Canet, Emma Rocaboy, Sofia Diego-Diàz, Robert A Whittington, Carl Julien, Emmanuel Plane. Methods for Biochemical Isolation of Insoluble Tau in Rodent Models of Tauopathies. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512674. the intracellular accumulation of microtubule-associated protein tau is a characteristic feature of tauopathies, a group of neurodegenerative diseases including alzheimer's disease. 2024-03-21 2024-03-24 mouse
Sarah Buchholz, Michael Bell-Simons, Cagla Cakmak, Jennifer Klimek, Li Gan, Hans Zempe. Cultivation, Differentiation, and Lentiviral Transduction of Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Glutamatergic Neurons for Studying Human Tau. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512688. tau pathology is a major hallmark of many neurodegenerative diseases summarized under the term tauopathies. 2024-03-21 2024-03-24 human
Felix Langerscheidt, Michael Bell-Simons, Hans Zempe. Differentiating SH-SY5Y Cells into Polarized Human Neurons for Studying Endogenous and Exogenous Tau Trafficking: Four Protocols to Obtain Neurons with Noradrenergic, Dopaminergic, and Cholinergic Properties. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512687. pathological alterations of the neuronal tau protein are characteristic for many neurodegenerative diseases, called tauopathies. 2024-03-21 2024-03-24 human
Yongna Yuan, Xuqi Mao, Xiaohang Pan, Ruisheng Zhang, Wei S. Kinetic Ensemble of Tau Protein through the Markov State Model and Deep Learning Analysis. Journal of chemical theory and computation. 2024-03-19. PMID:38501645. the ordered assembly of tau protein into filaments characterizes alzheimer's and other neurodegenerative diseases, and thus, stabilization of tau protein is a promising avenue for tauopathies therapy. 2024-03-19 2024-03-21 Not clear
Zerui Wang, Ling Wu, Maria Gerasimenko, Tricia Gilliland, Steven A Gunzler, Vincenzo Donadio, Rocco Liguori, Bin Xu, Wen-Quan Zo. Seeding Activity of Skin Misfolded Tau as a Biomarker for Tauopathies. Research square. 2024-03-18. PMID:38496453. background tauopathies are a group of age-related neurodegenerative diseases characterized by the accumulation of pathologically phosphorylated tau protein in the brain, leading to prion-like propagation and aggregation. 2024-03-18 2024-03-20 Not clear
Goonho Park, Angela Galdamez, Keon-Hyoung Song, Masako Le, Kyle Kim, Jonathan H Li. Ethnic variation and structure-function analysis of tauopathy-associated medRxiv : the preprint server for health sciences. 2024-03-18. PMID:38496636. in addition to its central position in intracellular stress regulation, human gwas identify eif2ak3 as a risk factor in tauopathies, neurodegenerative diseases caused by aberrant tau protein accumulation. 2024-03-18 2024-03-20 human
Hong Xu, Qi Qiu, Peng Hu, Kevt'her Hoxha, Elliot Jang, Mia O'Reilly, Christopher Kim, Zhuohao He, Nicholas Marotta, Lakshmi Changolkar, Bin Zhang, Hao Wu, Gerard D Schellenberg, Brian Kraemer, Kelvin C Luk, Edward B Lee, John Q Trojanowski, Kurt R Brunden, Virginia M-Y Le. MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons. Acta neuropathologica. vol 147. issue 1. 2024-03-13. PMID:38472475. inclusions comprised of microtubule-associated protein tau (tau) are implicated in a group of neurodegenerative diseases, collectively known as tauopathies, that include alzheimer's disease (ad). 2024-03-13 2024-03-15 mouse
Marina Han, Aleen Saxton, Heather Currey, Sarah M Waldherr, Nicole F Liachko, Brian C Kraeme. Transgenic Dendra2::tau expression allows in vivo monitoring of tau proteostasis in C. elegans. Disease models & mechanisms. 2024-03-12. PMID:38469687. protein homeostasis is perturbed in aging-related neurodegenerative diseases called tauopathies, which are pathologically characterized by aggregation of the microtubule-associated protein tau. 2024-03-12 2024-03-14 caenorhabditis_elegans
Carolina Lucía Facal, Iván Fernández Bessone, Javier Andrés Muñiz, A Ezequiel Pereyra, Olivia Pedroncini, Indiana Páez-Paz, Ramiro Clerici-Delville, Cayetana Arnaiz, Leandro Urrutia, Germán Falasco, Carla Verónica Argañaraz, Trinidad Saez, Antonia Marin-Burgin, Mariano Soiza-Reilly, Tomás Falzone, María Elena Aval. Tau reduction with artificial microRNAs modulates neuronal physiology and improves tauopathy phenotypes in mice. Molecular therapy : the journal of the American Society of Gene Therapy. 2024-02-04. PMID:38310353. abnormal tau accumulation is the hallmark of several neurodegenerative diseases, named tauopathies. 2024-02-04 2024-02-06 mouse
Maria do Socorro do Nascimento Amorim, Álefe Roger Silva França, Ralph Santos-Oliveira, Jonas Rodrigues Sanches, Thamys Marinho Melo, Bruno Araújo Serra Pinto, Leandro R S Barbosa, Luciana Magalhães Rebelo Alenca. Atomic Force Microscopy Applied to the Study of Tauopathies. ACS chemical neuroscience. 2024-02-02. PMID:38305187. tauopathies are neurodegenerative diseases featured by aggregation of phosphorylated tau protein inside neurons, leading to functional loss and progressive neurotoxicity. 2024-02-02 2024-02-04 Not clear
Courtney Lane-Donovan, Adam L Boxe. Disentangling tau: One protein, many therapeutic approaches. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2024-01-26. PMID:38278659. the tauopathies encompass over 20 adult neurodegenerative diseases and are characterized by the dysfunction and accumulation of insoluble tau protein. 2024-01-26 2024-01-29 Not clear
Eduardo Pena, Rocio San Martin-Salamanca, Samia El Alam, Karen Flores, Karem Arriaz. Tau Protein Alterations Induced by Hypobaric Hypoxia Exposure. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38255962. tauopathies are a group of neurodegenerative diseases whose central feature is dysfunction of the microtubule-associated protein tau (mapt). 2024-01-23 2024-01-25 Not clear
Ling Wu, Stephanie Arvai, Shih-Hsiu J Wang, Andy J Liu, Bin X. Differential diagnosis of mild cognitive impairment of Alzheimer's disease by Simoa p-tau181 measurements with matching plasma and CSF. Frontiers in molecular neuroscience. vol 16. 2024-01-23. PMID:38260807. misfolded phosphorylated tau aggregates (p-tau) are present in multiple neurodegenerative diseases known as "tauopathies", with the most common being ad. 2024-01-23 2024-01-25 human
Brianne B Rogers, Ashlyn G Anderson, Shelby N Lauzon, M Natalie Davis, Rebecca M Hauser, Sydney C Roberts, Ivan Rodriguez-Nunez, Katie Trausch-Lowther, Erin A Barinaga, Paige I Hall, Matthew T Knuesel, Jared W Taylor, Mark Mackiewicz, Brian S Roberts, Sara J Cooper, Lindsay F Rizzardi, Richard M Myers, J Nicholas Cochra. Neuronal MAPT expression is mediated by long-range interactions with cis-regulatory elements. American journal of human genetics. 2024-01-17. PMID:38232730. tauopathies are a group of neurodegenerative diseases defined by abnormal aggregates of tau, a microtubule-associated protein encoded by mapt. 2024-01-17 2024-01-20 human
Morrie Lam, Szu-Yu Kuo, Surya Reis, Jason E Gestwicki, M Catarina Silva, Stephen J Haggart. Cholesterol Dysregulation Drives Seed-Dependent Tau Aggregation in Patient Stem Cell-Derived Models of Tauopathy. bioRxiv : the preprint server for biology. 2024-01-03. PMID:38168389. tauopathies are a class of neurodegenerative diseases characterized by the progressive misfolding and accumulation of pathological tau protein in focal regions of the brain, leading to insidious neurodegeneration. 2024-01-03 2024-01-06 Not clear