| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jesus Alfonso Armijo Gómez, Miguel A Fernandez-Garcia, Ana Camacho, Marlin Liz, Carlos Ortez, Miguel Lafuente-Hidalgo, Laura Toledo Bravo-de Laguna, Berta Estévez-Arias, Laura Carrera-García, Jessica Expósito-Escudero, Jana Domínguez-Carral, Andres Nascimento, Daniel Natera-de Benit. Epilepsy in Duchenne and Becker muscular dystrophies. Annals of clinical and translational neurology. 2024-05-02. PMID:38693632. |
duchenne and becker muscular dystrophies (dmd and bmd) are dystrophinopathies caused by variants in dmd gene, resulting in reduced or absent dystrophin. |
2024-05-02 |
2024-05-04 |
Not clear |
| Kadalraja Raghavan, Thanasekar Sivakumar, Koji Ichiyama, Naoki Yamamoto, Mangaleswaran Balamurugan, Vidyasagar Devaprasad Dedeepiya, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel Jk Abraha. Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical study. Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology. vol 42. issue 4. 2024-02-26. PMID:38406382. |
muscular dystrophies other than duchenne muscular dystrophy (dmd) are genetic diseases characterized by increasing muscle weakness, loss of ambulation, and ultimately cardiac and respiratory failure. |
2024-02-26 |
2024-02-28 |
Not clear |
| Kadalraja Raghavan, Thanasekar Sivakumar, Koji Ichiyama, Naoki Yamamoto, Mangaleswaran Balamurugan, Vidyasagar Devaprasad Dedeepiya, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel Jk Abraha. Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical study. Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology. vol 42. issue 4. 2024-02-26. PMID:38406382. |
having demonstrated the efficacy of a n-163 strain of aureobasidium pullulans (neu-refix) produced b-1, 3-1,6-glucan in pre-clinical and clinical studies of duchenne muscular dystrophy (dmd) earlier, we assessed the effectiveness of this novel beta glucan in the other muscular dystrophies in the present study. |
2024-02-26 |
2024-02-28 |
Not clear |
| Sven Koehler, Julian Kuhm, Tyler Huffaker, Daniel Young, Animesh Tandon, Florian Andre, Norbert Frey, Gerald Greil, Tarique Hussain, Sandy Engelhard. Artificial Intelligence to derive aligned strain in cine CMR to detect patients with myocardial fibrosis: an open and scrutinizable approach. Research square. 2024-01-23. PMID:38260274. |
rare pathologies like duchenne muscular dystrophies (dmd) are monitored with repeated late gadolinium-enhanced (lge) cmr for identification of myocardial fibrosis. |
2024-01-23 |
2024-01-25 |
Not clear |
| Alice Maria Luderitz Hoefel, Cesar Augusto Weschenfelder, Bruna Faria Rosa, Karina Carvalho Donis, Jonas Alex Morales Saut. Empowerment of genetic information by women at-risk of being carriers of Duchenne and Becker muscular dystrophies. Journal of community genetics. 2024-01-02. PMID:38165635. |
the emergence of therapies acting on specific molecular targets for duchenne and becker muscular dystrophies (dbmd) led to expanded access of diagnostic dmd analysis. |
2024-01-02 |
2024-01-10 |
Not clear |
| Giorgia Querin, Marina Colell. Gene therapy for primary myopathies: literature review and prospects. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. vol 30. issue 8S1. 2023-12-03. PMID:38043978. |
focusing on primary myopathies, including duchenne muscular dystrophy (dmd), limb-girdle muscular dystrophies (lgmds), x-linked myotubular myopathy (xlmtm), and pompe disease, we review the ongoing pre-clinical and clinical trials that underscore the therapeutic promise of raav-based gene therapies. |
2023-12-03 |
2023-12-10 |
Not clear |
| Miranda D Grounds, Erin M Lloy. Considering the Promise of Vamorolone for Treating Duchenne Muscular Dystrophy. Journal of neuromuscular diseases. 2023-11-06. PMID:37927274. |
extensive clinical trials (ongoing) have investigated the use of vamorolone for dmd, with two trials also for limb-girdle muscular dystrophies including dysferlinopathy (current), plus a variety of pre-clinical trials published. |
2023-11-06 |
2023-11-08 |
Not clear |
| Nahla O Mousa, Ahmed Abdellatif, Nagia Fahmy, Hassan El-Fawal, Ahmed Osma. MicroRNAs as a Tool for Differential Diagnosis of Neuromuscular Disorders. Neuromolecular medicine. 2023-10-19. PMID:37856057. |
some of the disorders like duchenne muscular dystrophy (dmd), becker muscular dystrophy (bmd), congenital muscular dystrophies (cmds), limb-girdle muscular dystrophies (lgmd), and mild spinal muscular atrophy (sma) type iii share several presenting clinical features, and hence, diagnosis is usually a challenging task. |
2023-10-19 |
2023-11-08 |
human |
| V M Suslov, L N Lieberman, P G Carlier, G N Ponomarenko, D O Ivanov, D I Rudenko, G A Suslova, E I Adula. Efficacy and safety of hydrokinesitherapy in patients with dystrophinopathy. Frontiers in neurology. vol 14. 2023-08-11. PMID:37564736. |
duchenne muscular dystrophy (dmd) is one of the most common forms of hereditary muscular dystrophies in childhood and is characterized by steady progression and early disability. |
2023-08-11 |
2023-08-16 |
Not clear |
| Carlos Pascual-Morena, Iván Cavero-Redondo, Irene Sequí-Domínguez, Eva Rodríguez-Gutiérrez, María Eugenia Visier-Alfonso, Vicente Martínez-Vizcaín. Intelligence quotient-genotype association in dystrophinopathies: a systematic review and meta-analysis. Neuropathology and applied neurobiology. 2023-06-14. PMID:37312416. |
becker and duchenne muscular dystrophies (bmd and dmd) are associated with intelligence quotients (iq) lower than the normative values, and it is suggested that iq is negatively correlated with the number of affected isoforms (i.e., dp427, dp140, dp71). |
2023-06-14 |
2023-08-14 |
Not clear |
| Laura Yedigaryan, Maurilio Sampaoles. Extracellular vesicles and Duchenne muscular dystrophy pathology: Modulators of disease progression. Frontiers in physiology. vol 14. 2023-03-09. PMID:36891137. |
duchenne muscular dystrophy (dmd) is a devastating disorder and is considered to be one of the worst forms of inherited muscular dystrophies. |
2023-03-09 |
2023-08-14 |
Not clear |
| Sarinya Summa, Chupong Ittiwut, Pimchanok Kulsirichawaroj, Tanitnun Paprad, Surachai Likasitwattanakul, Oranee Sanmaneechai, Ponghatai Boonsimma, Kanya Suphapeetiporn, Vorasuk Shotelersu. Utilisation of exome sequencing for muscular disorders in Thai paediatric patients: diagnostic yield and mutational spectrum. Scientific reports. vol 13. issue 1. 2023-01-25. PMID:36697461. |
the remaining 43 patients from 42 families could be classified into three groups: group 1, mlpa-negative duchenne muscular dystrophy (dmd) with 9 patients (9/43; 21%), group 2, other muscular dystrophies (md) with 18 patients (18/43; 42%) and group 3, congenital myopathies (cm) with 16 patients (16/43; 37%). |
2023-01-25 |
2023-08-14 |
Not clear |
| Hilal Kalkan, Ester Pagano, Debora Paris, Elisabetta Panza, Mariarosaria Cuozzo, Claudia Moriello, Fabiana Piscitelli, Armita Abolghasemi, Elisabetta Gazzerro, Cristoforo Silvestri, Raffaele Capasso, Andrea Motta, Roberto Russo, Vincenzo Di Marzo, Fabio Arturo Iannott. Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy. EMBO molecular medicine. 2023-01-03. PMID:36594243. |
in sum, we propose a novel disease-modifying approach in dmd that may have benefits also in other muscular dystrophies. |
2023-01-03 |
2023-08-14 |
mouse |
| Catherine I Soderstrom, Jennifer Larsen, Carolina Owen, David Gifondorwa, David Beidler, Florence H Yong, Patricia Conrad, Hendrik Neubert, Steven A Moore, Mohamed Hassanei. Development and Validation of a Western Blot Method to Quantify Mini-Dystrophin in Human Skeletal Muscle Biopsies. The AAPS journal. vol 25. issue 1. 2022-12-20. PMID:36539515. |
therefore, reliable methods are needed to monitor dystrophin expression and assess the efficacy of new therapies for muscular dystrophies such as dmd and becker muscular dystrophy (bmd). |
2022-12-20 |
2023-08-14 |
human |
| Lily Den Hartog, Atsushi Asakur. Implications of notch signaling in duchenne muscular dystrophy. Frontiers in physiology. vol 13. 2022-10-14. PMID:36237531. |
here, we explore the connection between the notch signaling pathway and dmd, as well as how notch signaling may be targeted to improve the muscle degeneration seen in muscular dystrophies. |
2022-10-14 |
2023-08-14 |
Not clear |
| Carlos D Vera, Angela Zhang, Paul D Pang, Joseph C W. Treating Duchenne Muscular Dystrophy: The Promise of Stem Cells, Artificial Intelligence, and Multi-Omics. Frontiers in cardiovascular medicine. vol 9. 2022-04-01. PMID:35360042. |
three new advances are poised to change the landscape of therapies for muscular dystrophies such as dmd. |
2022-04-01 |
2023-08-13 |
human |
| Francesca M Alves, Kai Kysenius, Marissa K Caldow, Justin P Hardee, Jin D Chung, Jennifer Trieu, Dominic J Hare, Peter J Crouch, Scott Ayton, Ashley I Bush, Gordon S Lynch, René Koopma. Iron overload and impaired iron handling contribute to the dystrophic pathology in models of Duchenne muscular dystrophy. Journal of cachexia, sarcopenia and muscle. 2022-03-06. PMID:35249268. |
oxidative stress is implicated in the pathophysiology of duchenne muscular dystrophy (dmd, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. |
2022-03-06 |
2023-08-13 |
mouse |
| Carlos Pascual-Morena, Vicente Martínez-Vizcaíno, Alicia Saz-Lara, José Francisco López-Gil, Jaime Fernández-Bravo-Rodrigo, Iván Cavero-Redond. Epileptic disorders in Becker and Duchenne muscular dystrophies: a systematic review and meta-analysis. Journal of neurology. 2022-03-01. PMID:35229191. |
dystrophin alterations in the brain have been associated with an increased risk of epilepsy in becker and duchenne muscular dystrophies (bmd and dmd). |
2022-03-01 |
2023-08-13 |
human |
| Nader Salari, Behnaz Fatahi, Elahe Valipour, Mohsen Kazeminia, Reza Fatahian, Aliakbar Kiaei, Shamarina Shohaimi, Masoud Mohammad. Global prevalence of Duchenne and Becker muscular dystrophy: a systematic review and meta-analysis. Journal of orthopaedic surgery and research. vol 17. issue 1. 2022-02-16. PMID:35168641. |
duchenne (dmd) and becker (bmd) muscular dystrophies are located at the severe end of the spectrum that primarily affects skeletal muscle. |
2022-02-16 |
2023-08-13 |
human |
| Giuseppe Angelini, Giada Mura, Graziella Messin. Therapeutic approaches to preserve the musculature in Duchenne Muscular Dystrophy: The importance of the secondary therapies. Experimental cell research. 2021-12-09. PMID:34883113. |
muscular dystrophies (mds) are heterogeneous diseases, characterized by primary wasting of skeletal muscle, which in severe cases, such as duchenne muscular dystrophy (dmd), leads to wheelchair dependency, respiratory failure, and premature death. |
2021-12-09 |
2023-08-13 |
Not clear |