| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kamil Łątka, Stefanie Kickinger, Zuzanna Rzepka, Paula Zaręba, Gniewomir Latacz, Agata Siwek, Małgorzata Wolak, Dorota Stary, Monika Marcinkowska, Petrine Wellendorph, Dorota Wrześniok, Marek Bajd. Rational Search for Betaine/GABA Transporter 1 Inhibitors─ ACS chemical neuroscience. 2024-10-19. PMID:39425769. |
disturbances in gaba signaling are implicated in a multitude of neurologic and psychiatric conditions, including epilepsy, ischemia, anxiety, depression, insomnia, and mood disorders. |
2024-10-19 |
2024-10-22 |
Not clear |
| Kuldeep Tripathi, Somoday Hazra, Joyeeta Dutta Hazra, Silvia Mandel, Ruchi Anunu, Martin Kriebel, Hansjurgen Volkmer, Gal Richter-Levi. Selective knockdown of GABAA-α2 subunit in the dorsal dentate gyrus in adulthood induces anxiety, learning and memory deficits and impairs synaptic plasticity. The European journal of neuroscience. 2024-06-10. PMID:38858171. |
animal studies and clinical trials suggest that maintenance of gamma-aminobutyric acid (gaba)-ergic activity may be crucial in coping with stressful conditions, anxiety and mood disorders. |
2024-06-10 |
2024-06-14 |
rat |
| Renu Sharma, Pranjal Bansal, Lokesh Saini, Nidhi Sharma, Richa Dhingr. Zuranolone, a neuroactive drug, used in the treatment of postpartum depression by modulation of GABA Pharmacology, biochemistry, and behavior. 2024-02-22. PMID:38387651. |
zuranolone, a neuroactive drug, used in the treatment of postpartum depression by modulation of gaba postpartum depression [ppd] is a prevalent and debilitating mood disorder that affects mothers in the weeks to months after childbirth. |
2024-02-22 |
2024-02-25 |
Not clear |
| Christopher Sikes-Keilp, David R Rubino. GABA-ergic Modulators: New Therapeutic Approaches to Premenstrual Dysphoric Disorder. CNS drugs. 2023-08-05. PMID:37542704. |
research over the past two decades has suggested that the interaction between allopregnanolone, a neurosteroid derivative of progesterone, and the gamma-aminobutyric acid (gaba) system represents an important relationship underlying symptom genesis in reproductive-related mood disorders, including pmdd. |
2023-08-05 |
2023-08-14 |
Not clear |
| Molly Simmonite, Clara J Steeby, Stephan F Taylo. Medial Frontal Cortex GABA Concentrations in Psychosis Spectrum and Mood Disorders: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies. Biological psychiatry. 2022-11-05. PMID:36335069. |
medial frontal cortex gaba concentrations in psychosis spectrum and mood disorders: a meta-analysis of proton magnetic resonance spectroscopy studies. |
2022-11-05 |
2023-08-14 |
Not clear |
| Yann S Mineur, Tenna N Mose, Kathrine Lefoli Maibom, Steven T Pittenger, Alexa R Soares, Hao Wu, Seth R Taylor, Yaqing Huang, Marina R Picciott. ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms. Molecular psychiatry. 2022-09-01. PMID:36050437. |
indeed, dysregulation of inhibitory gaba interneurons in the amygdala has been implicated in human mood disorders. |
2022-09-01 |
2023-08-14 |
mouse |
| Vittoria Borgonetti, Paolo Governa, Fabrizio Manetti, Elisabetta Miraldi, Marco Biagi, Nicoletta Galeott. A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor. The Journal of pharmacy and pharmacology. vol 73. issue 9. 2021-09-15. PMID:33950239. |
honokiol, the main constituent of m. officinalis, is a gaba modulator and a cb1 agonist, which is deeply investigated for its role in modulating mood disorders. |
2021-09-15 |
2023-08-13 |
Not clear |
| Mounica Reddy-Thootkur, Nina Vanessa Kraguljac, Adrienne Carol Laht. The role of glutamate and GABA in cognitive dysfunction in schizophrenia and mood disorders - A systematic review of magnetic resonance spectroscopy studies. Schizophrenia research. 2021-08-25. PMID:32107102. |
the role of glutamate and gaba in cognitive dysfunction in schizophrenia and mood disorders - a systematic review of magnetic resonance spectroscopy studies. |
2021-08-25 |
2023-08-13 |
Not clear |
| Ji-Hong Liu, Ze-Lin Li, Yi-Si Liu, Huai-De Chu, Neng-Yuan Hu, Ding-Yu Wu, Lang Huang, Shu-Ji Li, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Ga. Astrocytic GABA Neuroscience bulletin. vol 36. issue 7. 2021-07-19. PMID:32166647. |
astrocytic gaba major depressive disorder (mdd) is a common mood disorder that affects almost 20% of the global population. |
2021-07-19 |
2023-08-13 |
Not clear |
| Sophie Schweizer-Schubert, Jennifer L Gordon, Tory A Eisenlohr-Moul, Samantha Meltzer-Brody, Katja M Schmalenberger, Radoslaw Slopien, Anna-Lena Zietlow, Ulrike Ehlert, Beate Ditze. Steroid Hormone Sensitivity in Reproductive Mood Disorders: On the Role of the GABA Frontiers in medicine. vol 7. 2021-02-16. PMID:33585496. |
steroid hormone sensitivity in reproductive mood disorders: on the role of the gaba women worldwide are two to three times more likely to suffer from depression in their lifetime than are men. |
2021-02-16 |
2023-08-13 |
Not clear |
| Mohammadreza Moradi, Massoud Saidijam, Reza Yadegarazari, Leila Jahangard, Maryam Seifi, Nasrin Matinnia, Ali Ghaleih. Genes Encoding GABA-β and HT1D Receptors in Bipolar I (Manic Phase) Patients. Basic and clinical neuroscience. vol 9. issue 2. 2020-10-01. PMID:29967672. |
according to the cumulative evidence, genes encoding gaba receptors inhibit neurotransmitters in cns and are intricately involved in the pathogenesis of mood disorders. |
2020-10-01 |
2023-08-13 |
Not clear |
| Juan Francisco Rodríguez-Landa, Jonathan Cueto-Escobedo, Luis Ángel Flores-Aguilar, Gilberto Uriel Rosas-Sánchez, María de Jesús Rovirosa-Hernández, Francisco García-Orduña, Miguel Carro-Juáre. The Aqueous Crude Extracts of Montanoa frutescens and Montanoa grandiflora Reduce Immobility Faster Than Fluoxetine Through GABA Journal of evidence-based integrative medicine. vol 23. 2019-11-20. PMID:29540064. |
the aqueous crude extracts of montanoa frutescens and montanoa grandiflora reduce immobility faster than fluoxetine through gaba montanoa frutescens and montanoa grandiflora have been indistinctly used for centuries in traditional mexican medicine for reproductive impairments, anxiety, and mood disorders. |
2019-11-20 |
2023-08-13 |
Not clear |
| Natalia Górska, Jakub Słupski, Łukasz P Szałach, Adam Włodarczyk, Joanna Szarmach, Katarzyna Jakuszkowiak-Wojten, Maria Gałuszko-Węgielnik, Alina Wilkowska, Mariusz Stanisław Wiglusz, Wiesław Jerzy Cubał. Magnesium and ketamine in the treatment of depression. Psychiatria Danubina. vol 31. issue Suppl 3. 2019-10-23. PMID:31488789. |
the results of abnormalities in glutamate and γ-aminobutyric acid (gaba) systems in the brains of people with mood disorders allowed to develop new theories regarding pathophysiology of these disorders. |
2019-10-23 |
2023-08-13 |
Not clear |
| Samuel T Wilkinson, Gerard Sanacor. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug discovery today. vol 24. issue 2. 2019-07-31. PMID:30447328. |
mounting evidence collected over the past two decades suggests the amino acid neurotransmitter systems (glutamate and gaba) serve central roles in the pathophysiology of mood disorders. |
2019-07-31 |
2023-08-13 |
Not clear |
| Felipe Borges Almeida, Rosane Gomez, Helena Maria Tannhauser Barros, Maurício Schüler Ni. Hemisphere-dependent Changes in mRNA Expression of GABA Neuroscience. vol 397. 2019-03-07. PMID:30481569. |
hemisphere-dependent changes in mrna expression of gaba allopregnanolone is a neurosteroid implicated in mood disorders such as depression and anxiety. |
2019-03-07 |
2023-08-13 |
Not clear |
| Saiful Alom Siddique, Thangavel Tamilselvan, Manikkannan Vishnupriya, Elumalai Balamuruga. Evaluation of Neurotransmitter Alterations in Four Distinct Brain Regions After Rapid Eye Movement Sleep Deprivation (REMSD) Induced Mania-Like Behaviour in Swiss Albino Mice. Neurochemical research. vol 43. issue 6. 2018-10-15. PMID:29671235. |
a number of neurotransmitter systems have been implicated in contributing to the pathology of mood disorders, including those of dopamine (da), serotonin (5-ht), norepinephrine (ne) and γ-aminobutyric acid (gaba). |
2018-10-15 |
2023-08-13 |
mouse |
| S Hossein Fatemi, Timothy D Folso. GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism. Schizophrenia research. vol 167. issue 1-3. 2016-06-27. PMID:25432637. |
gaba receptor subunit distribution and fmrp-mglur5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism. |
2016-06-27 |
2023-08-13 |
mouse |
| Zhen Li, Shu-Cheng An, Jiang-Na L. [The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 45. issue 3. 2016-05-26. PMID:25219270. |
gamma-aminobutyric acid (gaba) is the major inhibitory neurotransmitter of the central nervous system (cns) in mammalian, which involved in several mood disorders such as anxiety, depression and schizophrenia. |
2016-05-26 |
2023-08-13 |
Not clear |
| Po W Wang, Napapon Sailasuta, Rebecca A Chandler, Terence A Kette. Magnetic resonance spectroscopic measurement of cerebral gamma-aminobutyric acid concentrations in patients with bipolar disorders. Acta neuropsychiatrica. vol 18. issue 2. 2016-03-23. PMID:26989801. |
animal models of depression and psychopharmacological mechanisms of action suggest the importance of the gamma-amino butyric acid (gaba) system in the pathophysiology of mood disorders. |
2016-03-23 |
2023-08-13 |
Not clear |
| Po W Wang, Napapon Sailasuta, Rebecca A Chandler, Terence A Kette. Magnetic resonance spectroscopic measurement of cerebral gamma-aminobutyric acid concentrations in patients with bipolar disorders. Acta neuropsychiatrica. vol 18. issue 2. 2016-03-23. PMID:26989801. |
magnetic resonance spectroscopy (mrs) provides an opportunity to noninvasively assess cerebral gaba concentrations in anterior paralimbic circuits that have been implicated in mood disorders. |
2016-03-23 |
2023-08-13 |
Not clear |