| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ch Kuhlmann, W Scheidemann, M Bachmann, G F Schusse. [Brainstem auditory evoked responses in horses with hearing loss and during general anesthesia]. Schweizer Archiv fur Tierheilkunde. vol 166. issue 7. 2024-07-08. PMID:38975650. |
horses with right sided external otitis: right moderate to severe conductive hearing loss (significantly prolonged latencies of i, iii, v and interpeak latencies i-iii, i-v, iii-v; thresholds of hearing levels 60 to 80 db right); horses with left sided external otitis: left severe conductive hearing loss (no correct identification of baer peaks, latencies not measurable, 80 db); horse with left sided head trauma: severe left sided conductive hearing loss (blood in the left external ear canal, no visible tympanic membrane, no correct identification of baer peaks, latencies not measurable, 80 db); horses with head shaking: mild sensorineural hearing loss on both sides (on both sides osseous parts ii/iii with keratin scales of the junction, visible tympanic membranes, significantly prolonged v, i-iii, i-v, 40 db); moderate to severe skittish horses with chronic eye disease (mostly left sided equine recurrent uveitis): moderate sensorineural hearing loss on both sides (normal otoscopical findings, significantly prolonged latencies and interpeak latencies left; i-v, iii-v right, 60 db, pathological involvement in the auditory pathway of the brainstem between the cochlear nucleus and colliculus caudalis); horse with a tinnitus on both sides: mild sensorineural hearing loss on both sides (normal otoscopical findings, prolonged v, i-iii, i-v, iii-v, 40 db, pathology of auditory nerve, cochlear nucleus and above the level of this nucleus); american paint horses: sensorineurale deafness on both sides (normal otoscopical findings, absent baer peaks, isoelectric lines and 80 db on both sides). |
2024-07-08 |
2024-07-11 |
Not clear |
| Ruili Xie, Meijian Wang, Chuangeng Zhan. Mechanisms of age-related hearing loss at the auditory nerve central synapses and postsynaptic neurons in the cochlear nucleus. Hearing research. vol 442. 2023-12-19. PMID:38113793. |
mechanisms of age-related hearing loss at the auditory nerve central synapses and postsynaptic neurons in the cochlear nucleus. |
2023-12-19 |
2023-12-23 |
Not clear |
| Benjamin J Seicol, Shengyin Lin, Ruili Xi. Age-Related Hearing Loss Is Accompanied by Chronic Inflammation in the Cochlea and the Cochlear Nucleus. Frontiers in aging neuroscience. vol 14. 2022-04-14. PMID:35418849. |
age-related hearing loss is accompanied by chronic inflammation in the cochlea and the cochlear nucleus. |
2022-04-14 |
2023-08-13 |
mouse |
| Nicholas L Deep, Patricia L Purcell, Karen A Gordon, Blake C Papsin, J Thomas Roland, Susan B Waltzma. Cochlear Implantation in Infants: Evidence of Safety. Trends in hearing. vol 25. 2021-05-27. PMID:34028328. |
this was a multicenter, retrospective chart review of all children with severe-to-profound sensorineural hearing loss who underwent cochlear implantation with a cochlear nucleus implant system before 1 year of age. |
2021-05-27 |
2023-08-13 |
Not clear |
| Nicholas L Deep, Patricia L Purcell, Karen A Gordon, Blake C Papsin, J Thomas Roland, Susan B Waltzma. Cochlear Implantation in Infants: Evidence of Safety. Trends in hearing. vol 25. 2021-05-27. PMID:34028328. |
this study demonstrates the safety of ci surgery in infants and supports reducing the indication for cochlear implantation to younger than 1 year of age for children with bilateral, profound sensorineural hearing loss obtaining a cochlear nucleus implant system. |
2021-05-27 |
2023-08-13 |
Not clear |
| Meijian Wang, Chuangeng Zhang, Shengyin Lin, Yong Wang, Benjamin J Seicol, Robert W Ariss, Ruili Xi. Biased auditory nerve central synaptopathy is associated with age-related hearing loss. The Journal of physiology. vol 599. issue 6. 2021-04-20. PMID:33450070. |
we report that different subtypes of sgn central synapses converge at different ratios onto individual target cochlear nucleus neurons with distinct physiological properties, and show biased morphological and physiological changes during age-related hearing loss (arhl). |
2021-04-20 |
2023-08-13 |
Not clear |
| Seung-Hyun Chung, Sung Wook Jeong, Lee-Suk Ki. A Case of Auditory Neuropathy Caused by Pontine Hemorrhage in an Adult. Journal of audiology & otology. vol 21. issue 2. 2020-10-01. PMID:28704898. |
hearing loss can develop as a result of a pontine hemorrhage because there is an auditory conduction pathway in the cochlear nucleus of the pons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yong Wang, Meijian Wang, Ruili Xi. D-Stellate Neurons of the Ventral Cochlear Nucleus Decrease in Auditory Nerve-Evoked Activity during Age-Related Hearing Loss. Brain sciences. vol 9. issue 11. 2020-09-28. PMID:31683609. |
age-related hearing loss (arhl) is associated with weakened inhibition in the central auditory nervous system including the cochlear nucleus. |
2020-09-28 |
2023-08-13 |
mouse |
| Takaomi Kurioka, Sachiyo Mogi, Taku Yamashit. Transient Conductive Hearing Loss Regulates Cross-Modal VGLUT Expression in the Cochlear Nucleus of C57BL/6 Mice. Brain sciences. vol 10. issue 5. 2020-09-28. PMID:32365514. |
transient conductive hearing loss regulates cross-modal vglut expression in the cochlear nucleus of c57bl/6 mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Masao Noda, Miyako Hatano, Tsuyoshi Hattori, Mika Takarada-Iemata, Tomohiro Shinozaki, Hisashi Sugimoto, Makoto Ito, Tomokazu Yoshizaki, Osamu Hor. Microglial activation in the cochlear nucleus after early hearing loss in rats. Auris, nasus, larynx. vol 46. issue 5. 2020-01-28. PMID:30827793. |
microglial activation in the cochlear nucleus after early hearing loss in rats. |
2020-01-28 |
2023-08-13 |
rat |
| Cheryl Clarkson, Flora M Antunes, Maria E Rubi. Conductive Hearing Loss Has Long-Lasting Structural and Molecular Effects on Presynaptic and Postsynaptic Structures of Auditory Nerve Synapses in the Cochlear Nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 39. 2017-08-22. PMID:27683915. |
conductive hearing loss has long-lasting structural and molecular effects on presynaptic and postsynaptic structures of auditory nerve synapses in the cochlear nucleus. |
2017-08-22 |
2023-08-13 |
rat |
| Thomas Jose Eluvathingal Muttikkal, Bradley W Kesser, Sugoto Mukherje. Isolated contralateral sudden sensorineural hearing loss: an unusual manifestation of pontine infarct. The neuroradiology journal. vol 27. issue 4. 2017-02-06. PMID:25196624. |
lesions in the ascending central auditory pathways cranial to the cochlear nucleus seldom result in unilateral hearing loss due to decussation of the central auditory pathways at multiple levels. |
2017-02-06 |
2023-08-13 |
Not clear |
| Kristen Rak, Johannes Völker, Lukas Jürgens, Christine Völker, Silke Frenz, Agmal Scherzad, Philipp Schendzielorz, Sibylle Jablonka, Robert Mlynski, Andreas Radeloff, Rudolf Hage. Cochlear nucleus whole mount explants promote the differentiation of neuronal stem cells from the cochlear nucleus in co-culture experiments. Brain research. vol 1616. 2016-03-02. PMID:25960344. |
consequently, the presented results provide a first step for the possible application of stem cells to repair the disorganization of the cochlear nucleus, which occurs after hearing loss. |
2016-03-02 |
2023-08-13 |
Not clear |
| Tao Xue, Li Wei, Ding-Jun Zha, Li Qiao, Lian-Jun Lu, Fu-Quan Chen, Jian-Hua Qi. Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway. International journal of molecular medicine. vol 35. issue 3. 2015-10-05. PMID:25605314. |
recently, neural stem cells (nscs) from the cochlear nuclei have been identified, indicating a potential direction for the treatment of sensorineural hearing loss. |
2015-10-05 |
2023-08-13 |
rat |
| Tao Xue, Li Wei, Yu Zhao, Ding-Jun Zha, Li Qiao, Jian-Hua Qiu, Lian-Jun L. Favorable proliferation and differentiation capabilities of neural precursor cells derived from rat cochlear nucleus. International journal of clinical and experimental pathology. vol 7. issue 11. 2015-09-02. PMID:25550799. |
in conclusion, npcs isolated from the cochlear nucleus can proliferate and differentiate into functional neurons, which offers a potential strategy for sensorineural hearing loss treatment. |
2015-09-02 |
2023-08-13 |
rat |
| Kristen Rak, Johannes Völker, Silke Frenz, Agmal Scherzad, Philipp Schendzielorz, Andreas Radeloff, Sibylle Jablonka, Rudolf Hagen, Robert Mlynsk. Effects of the neurotrophic factors BDNF, NT-3, and FGF2 on dissociated neurons of the cochlear nucleus. Neuroreport. vol 25. issue 12. 2015-02-24. PMID:24978398. |
the results presented represent fundamental research on auditory neurons, but might be one step toward defining novel therapeutic strategies in the future to prevent cochlear nucleus degeneration induced by hearing loss. |
2015-02-24 |
2023-08-13 |
mouse |
| Kristen Rak, Johannes Völker, Silke Frenz, Agmal Scherzad, Philipp Schendzielorz, Andreas Radeloff, Sibylle Jablonka, Rudolf Hagen, Robert Mlynsk. Effects of the neurotrophic factors BDNF, NT-3, and FGF2 on dissociated neurons of the cochlear nucleus. Neuroreport. vol 25. issue 12. 2015-02-24. PMID:24978398. |
the cochlear nucleus is the first relay station for acoustic information in the auditory pathway and its cellular integrity is affected by hearing loss. |
2015-02-24 |
2023-08-13 |
mouse |
| Verónica Fuentes-Santamaría, Juan C Alvarado, Diego F López-Muñoz, Pedro Melgar-Rojas, María C Gabaldón-Ull, José M Jui. Glia-related mechanisms in the anteroventral cochlear nucleus of the adult rat in response to unilateral conductive hearing loss. Frontiers in neuroscience. vol 8. 2014-10-29. PMID:25352772. |
these results suggest that microglial cells but not astrocytes may act as dynamic modulators of synaptic transmission in the cochlear nucleus immediately following unilateral hearing loss. |
2014-10-29 |
2023-08-13 |
rat |
| Ruili Xie, Paul B Mani. Glycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss. Journal of neurophysiology. vol 110. issue 8. 2014-06-20. PMID:23904491. |
glycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss. |
2014-06-20 |
2023-08-12 |
mouse |
| H Wang, G Yin, K Rogers, C Miralles, A L De Blas, M E Rubi. Monaural conductive hearing loss alters the expression of the GluA3 AMPA and glycine receptor α1 subunits in bushy and fusiform cells of the cochlear nucleus. Neuroscience. vol 199. 2012-04-06. PMID:22044924. |
monaural conductive hearing loss alters the expression of the glua3 ampa and glycine receptor α1 subunits in bushy and fusiform cells of the cochlear nucleus. |
2012-04-06 |
2023-08-12 |
Not clear |