| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liqin Hu, Yan Liu, Ziwei Yuan, Haokun Guo, Ran Duan, Pingyang Ke, Yuan Meng, Xin Tian, Fei Xia. Glucose-6-phosphate dehydrogenase alleviates epileptic seizures by repressing reactive oxygen species production to promote signal transducer and activator of transcription 1-mediated N-methyl-d-aspartic acid receptors inhibition. Redox biology. vol 74. 2024-06-14. PMID:38875958. |
collectively, our findings highlight the pivotal role of g6pd in modulating epileptogenesis, and suggest its potential as a therapeutic target for epilepsy. |
2024-06-14 |
2024-06-17 |
Not clear |
| Daria Ponomareva, Anton Ivanov, Piotr Bregestovsk. Analysis of the Effects of Pentose Phosphate Pathway Inhibition on the Generation of Reactive Oxygen Species and Epileptiform Activity in Hippocampal Slices. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339211. |
g6pd dysfunction, affecting the ppp, is implicated in neurological disorders, including epilepsy. |
2024-02-10 |
2024-02-12 |
mouse |
| Daria Ponomareva, Anton Ivanov, Piotr Bregestovsk. Analysis of the Effects of Pentose Phosphate Pathway Inhibition on the Generation of Reactive Oxygen Species and Epileptiform Activity in Hippocampal Slices. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339211. |
using the specific g6pd inhibitor g6pdi-1, we assessed its effects on mouse hippocampal slices, examining intracellular ros, glucose/oxygen consumption, the nad(p)h level and ros production during synaptic stimulation and in the 4ap epilepsy model. |
2024-02-10 |
2024-02-12 |
mouse |
| Meryem Alagoz, Nasim Kherad, Ezgi Gunger, Selin Kaymaz, Adnan Yukse. The New CIC Mutation Associates with Mental Retardation and Severity of Seizure in Turkish Child with a Rare Class I Glucose-6-Phosphate Dehydrogenase Deficiency. Journal of molecular neuroscience : MN. vol 70. issue 12. 2021-08-19. PMID:32535712. |
here, we present the case of epilepsy in an 8-year-old child with a hemizygous variation in g6pd gene and heterozygous mutation in cic gene, resulting in focal epileptiform activity and hypsarrhythmia in electroencephalography (eeg), seizures, psychomotor retardation, speech impairment, intellectual disability, developmental regression, and learning difficulties. |
2021-08-19 |
2023-08-13 |
Not clear |