| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chang Li, Yi Cai, Yongmin Chen, Jingyi Tong, Youbin Li, Dong Liu, Yun Wang, Zhiping Li, Yan Wang, Qifu L. ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR. Redox biology. vol 75. 2024-07-09. PMID:38981367. |
the transporter protein abc subfamily g member 2 (abcg2) is implicated in epilepsy; however, its specific role remains unclear. |
2024-07-09 |
2024-07-12 |
mouse |
| Chang Li, Yi Cai, Yongmin Chen, Jingyi Tong, Youbin Li, Dong Liu, Yun Wang, Zhiping Li, Yan Wang, Qifu L. ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR. Redox biology. vol 75. 2024-07-09. PMID:38981367. |
in this study, we assessed changes in abcg2 expression and its role in epilepsy both in vitro and in vivo. |
2024-07-09 |
2024-07-12 |
mouse |
| Jing Yang, Jinxingyi Wang, Lijie Ning, Changsong Wu, Yang Liu, Jie Xia, Yanping Guan, Qian Liu, Jianghuan Zhen. Influence of UGT2B7, UGT1A4 and ABCG2 Polymorphisms on the Pharmacokinetics and Therapeutic Efficacy of Lamotrigine in Patients with Epilepsy. European journal of drug metabolism and pharmacokinetics. 2024-05-06. PMID:38709450. |
influence of ugt2b7, ugt1a4 and abcg2 polymorphisms on the pharmacokinetics and therapeutic efficacy of lamotrigine in patients with epilepsy. |
2024-05-06 |
2024-05-08 |
Not clear |
| Jing Yang, Jinxingyi Wang, Lijie Ning, Changsong Wu, Yang Liu, Jie Xia, Yanping Guan, Qian Liu, Jianghuan Zhen. Influence of UGT2B7, UGT1A4 and ABCG2 Polymorphisms on the Pharmacokinetics and Therapeutic Efficacy of Lamotrigine in Patients with Epilepsy. European journal of drug metabolism and pharmacokinetics. 2024-05-06. PMID:38709450. |
the aim of the study was to investigate the impact of genetic polymorphism of the metabolizing enzymes (ugt2b7, ugt1a4) and transporter (abcg2) on the pharmacokinetics and therapeutic efficacy of lamotrigine in patients with epilepsy. |
2024-05-06 |
2024-05-08 |
Not clear |
| Ivana Šušak Sporiš, Nada Božina, Iva Klarica Domjanović, Davor Sporiš, Silvio Bašić, Ivana Bašić, Mila Lovrić, Lana Ganoci, Vladimir Trkulj. Breast cancer resistance protein polymorphism ABCG2 c.421C>A (rs2231142) moderates the effect of valproate on lamotrigine trough concentrations in adults with epilepsy. Fundamental & clinical pharmacology. 2023-10-04. PMID:37793994. |
breast cancer resistance protein polymorphism abcg2 c.421c>a (rs2231142) moderates the effect of valproate on lamotrigine trough concentrations in adults with epilepsy. |
2023-10-04 |
2023-10-07 |
Not clear |
| D J Nava-Cedeño, M C Alonso-Cerezo, A Sanz-García, L Vega-Zelaya, J J Gordillo-Perdomo, M Toledo-Heras, J Pastor-Gómez, C Torres-Díaz, P Pulido-Rivas, R García-Sol. [Association between single nucleotide genetic polymorphisms in ABC transporter genes with drug-resistant epilepsy in the Spanish population]. Revista de neurologia. vol 75. issue 9. 2022-10-26. PMID:36285445. |
the aim of the present study was to evaluate the association of 13 polymorphisms in the abcb1, abcc2, abcc5 and abcg2 genes with drug-resistant epilepsy (dre) in a spanish population. |
2022-10-26 |
2023-08-14 |
Not clear |
| Seyedeh Farnaz Mousavi, Kazem Hasanpour, Milad Nazarzadeh, Abolfazl Adli, Malihe Sadat Bazghandi, Alireza Asadi, Abolfazl Rad, Omid Gholam. ABCG2, SCN1A and CYP3A5 genes polymorphism and drug-resistant epilepsy in children: A case-control study. Seizure. vol 97. 2022-03-26. PMID:35338956. |
abcg2, scn1a and cyp3a5 genes polymorphism and drug-resistant epilepsy in children: a case-control study. |
2022-03-26 |
2023-08-13 |
Not clear |
| Seyedeh Farnaz Mousavi, Kazem Hasanpour, Milad Nazarzadeh, Abolfazl Adli, Malihe Sadat Bazghandi, Alireza Asadi, Abolfazl Rad, Omid Gholam. ABCG2, SCN1A and CYP3A5 genes polymorphism and drug-resistant epilepsy in children: A case-control study. Seizure. vol 97. 2022-03-26. PMID:35338956. |
we sought to assess the association of cyp3a5 (rs776746), scn1a (rs2298771) and abcg2 (rs2231137) candidate polymorphisms with drug-resistant epilepsy among iranian children with epilepsy. |
2022-03-26 |
2023-08-13 |
Not clear |
| Alberto Ortega-Vázquez, Ingrid Fricke-Galindo, Pedro Dorado, Helgi Jung-Cook, Iris E Martínez-Juárez, Nancy Monroy-Jaramillo, Irma S Rojas-Tomé, Eva Peñas-Lledó, Adrián Llerena, Marisol López-Lópe. Influence of genetic variants and antiepileptic drug co-treatment on lamotrigine plasma concentration in Mexican Mestizo patients with epilepsy. The pharmacogenomics journal. vol 20. issue 6. 2021-09-02. PMID:32483200. |
we simultaneously investigated the association of ugt1a1, ugt1a4, ugt2b7, abcb1, abcg2, and slc22a1 variants, as well as antiepileptic drug co-treatment, on ltg plasma concentration in 97 mexican mestizo (mm) patients with epilepsy. |
2021-09-02 |
2023-08-13 |
Not clear |
| Zhan-Zhang Wang, Yue-Feng Zhang, Wen-Can Huang, Xi-Pei Wang, Xiao-Jiao Ni, Hao-Yang Lu, Jin-Qing Hu, Shu-Hua Deng, Xiu-Qing Zhu, Huan-Shan Xie, Hong-Zhen Chen, Ming Zhang, Chang Qiu, Yu-Guan Wen, De-Wei Shan. Effects of Comedication and Genetic Factors on the Population Pharmacokinetics of Lamotrigine: A Prospective Analysis in Chinese Patients With Epilepsy. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31404235. |
this prospective study aimed to establish a population pharmacokinetics model for ltg in chinese patients with epilepsy and to investigate the effects of genetic variants in uridine diphosphate glucuronosyltransferase (ugt) 1a4, ugt2b7, mdr1, abcg2, abcc2, and slc22a1, as well as non-genetic factors, on ltg pharmacokinetics. |
2020-09-30 |
2023-08-13 |
Not clear |
| Juan Chen, Qibiao Su, Jiaming Qin, Yi Zhou, Honglian Ruan, Ziyi Chen, Zhuojia Chen, Hongliang Li, Yafang Zhou, Shan Zhou, Xueding Wang, Liemin Zhou, Min Huan. Correlation of MCT1 and ABCC2 gene polymorphisms with valproic acid resistance in patients with epilepsy on valproic acid monotherapy. Drug metabolism and pharmacokinetics. vol 34. issue 3. 2019-11-29. PMID:30952578. |
twelve snps involved in vpa transport pathways, including abcc2, abcc4, abcg2, mct1, mct2 and oatp2b1 were genotyped in 153 han chinese epilepsy patients. |
2019-11-29 |
2023-08-13 |
Not clear |
| Iva Klarica Domjanović, Mila Lovrić, Vladimir Trkulja, Željka Petelin-Gadže, Lana Ganoci, Ivana Čajić, Nada Božin. Interaction between ABCG2 421C>A polymorphism and valproate in their effects on steady-state disposition of lamotrigine in adults with epilepsy. British journal of clinical pharmacology. vol 84. issue 9. 2019-10-14. PMID:29791014. |
interaction between abcg2 421c>a polymorphism and valproate in their effects on steady-state disposition of lamotrigine in adults with epilepsy. |
2019-10-14 |
2023-08-13 |
Not clear |
| Juan Chen, Qi-Biao Su, Yu-Qian Tao, Jia-Ming Qin, Yi Zhou, Shan Zhou, Hong-Liang Li, Zhuo-Jia Chen, Ya-Fang Zhou, Lie-Min Zhou, Xue-Ding Wang, Min Huan. ABCC2 rs2273697 is associated with valproic acid concentrations in patients with epilepsy on valproic acid monotherapy. Die Pharmazie. vol 73. issue 5. 2019-01-17. PMID:29724294. |
in the present study, we investigated the association of 12 snps in abcc2, abcc4, abcg2, mct1, mct2, and oatp2b1 in 187 chinese patients with epilepsy on vpa monotherapy with the trough concentrations of vpa. |
2019-01-17 |
2023-08-13 |
Not clear |
| Chun-Hong Shen, Yin-Xi Zhang, Ru-Yi Lu, Bo Jin, Shan Wang, Zhi-Rong Liu, Ye-Lei Tang, Mei-Ping Din. Specific OCT1 and ABCG2 polymorphisms are associated with Lamotrigine concentrations in Chinese patients with epilepsy. Epilepsy research. vol 127. 2018-01-02. PMID:27610747. |
specific oct1 and abcg2 polymorphisms are associated with lamotrigine concentrations in chinese patients with epilepsy. |
2018-01-02 |
2023-08-13 |
Not clear |
| Chun-Hong Shen, Yin-Xi Zhang, Ru-Yi Lu, Bo Jin, Shan Wang, Zhi-Rong Liu, Ye-Lei Tang, Mei-Ping Din. Specific OCT1 and ABCG2 polymorphisms are associated with Lamotrigine concentrations in Chinese patients with epilepsy. Epilepsy research. vol 127. 2018-01-02. PMID:27610747. |
in this study, we are aiming to investigate the effects of oct1, abcg2, abcc2 and hnf4α genetic polymorphisms on plasma ltg concentrations and therapeutic efficacy in chinese patients with epilepsy. |
2018-01-02 |
2023-08-13 |
Not clear |
| Yafang Zhou, Xueding Wang, Hongliang Li, Jie Zhang, Ziyi Chen, Wen Xie, Jinxin Zhang, Jiali Li, Liemin Zhou, Min Huan. Polymorphisms of ABCG2, ABCB1 and HNF4α are associated with Lamotrigine trough concentrations in epilepsy patients. Drug metabolism and pharmacokinetics. vol 30. issue 4. 2016-05-09. PMID:26213157. |
polymorphisms of abcg2, abcb1 and hnf4α are associated with lamotrigine trough concentrations in epilepsy patients. |
2016-05-09 |
2023-08-13 |
Not clear |
| Yafang Zhou, Xueding Wang, Hongliang Li, Jie Zhang, Ziyi Chen, Wen Xie, Jinxin Zhang, Jiali Li, Liemin Zhou, Min Huan. Polymorphisms of ABCG2, ABCB1 and HNF4α are associated with Lamotrigine trough concentrations in epilepsy patients. Drug metabolism and pharmacokinetics. vol 30. issue 4. 2016-05-09. PMID:26213157. |
twelve single nucleotide polymorphisms (snps) involved in ltg metabolism and transport pathways, including ugt2b7, abcb1, abcg2, nr1i2 and hnf4α were genotyped in 140 chinese epilepsy patients. |
2016-05-09 |
2023-08-13 |
Not clear |
| Shabeesh Balan, Sumitha Prameela Bharathan, Neetha Nanoth Vellichiramal, Sanish Sathyan, Vijai Joseph, Kurupath Radhakrishnan, Moinak Banerje. Genetic association analysis of ATP binding cassette protein family reveals a novel association of ABCB1 genetic variants with epilepsy risk, but not with drug-resistance. PloS one. vol 9. issue 2. 2015-01-13. PMID:24586633. |
in the present study we inquired the role of multidrug transporters abcb1 and abcg2 variants in determining aed-resistance and susceptibility to epilepsy in three well-characterized cohorts comprising of mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) (prototype for aed-resistant epilepsy); juvenile myoclonic epilepsy (jme) (prototype for aed-responsive epilepsy); and healthy non-epileptic controls, in 738 subjects of malayalam speaking south indian ancestry. |
2015-01-13 |
2023-08-12 |
human |
| Patrick Kwan, Virginia Wong, Ping Wing Ng, Colin Hiu Tung Lui, Ngai Chuen Sin, Ka Sing Wong, Larry Bau. Gene-wide tagging study of the association between ABCC2, ABCC5 and ABCG2 genetic polymorphisms and multidrug resistance in epilepsy. Pharmacogenomics. vol 12. issue 3. 2011-07-20. PMID:21449672. |
to determine the association between polymorphisms of the multidrug transporter genes abcc2, abcc5 and abcg2, and drug resistance in epilepsy by genotyping comprehensive sets of tagging snps. |
2011-07-20 |
2023-08-12 |
Not clear |
| Patrick Kwan, Virginia Wong, Ping Wing Ng, Colin Hiu Tung Lui, Ngai Chuen Sin, Ka Sing Wong, Larry Bau. Gene-wide tagging study of the association between ABCC2, ABCC5 and ABCG2 genetic polymorphisms and multidrug resistance in epilepsy. Pharmacogenomics. vol 12. issue 3. 2011-07-20. PMID:21449672. |
gene-wide tagging study of the association between abcc2, abcc5 and abcg2 genetic polymorphisms and multidrug resistance in epilepsy. |
2011-07-20 |
2023-08-12 |
Not clear |