| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah M Milne, Anirudhya Lahiri, Cristina L Sanchez, Micah J Marshall, Ishrat Jahan, Gordon P Meare. Myelin oligodendrocyte glycoprotein reactive Th17 cells drive Janus Kinase 1 dependent transcriptional reprogramming in astrocytes and alter cell surface cytokine receptor profiles during experimental autoimmune encephalomyelitis. Scientific reports. vol 14. issue 1. 2024-06-07. PMID:38849434. |
myelin oligodendrocyte glycoprotein reactive th17 cells drive janus kinase 1 dependent transcriptional reprogramming in astrocytes and alter cell surface cytokine receptor profiles during experimental autoimmune encephalomyelitis. |
2024-06-07 |
2024-06-10 |
Not clear |
| Yaqiong Cui, Bo Wu, Jinying Wu, Shuyue Zhang, Pan Guo, Jianbo Shu, Dong Li, Chunquan Ca. Novel Genetic Variants Distinguishing Myelin Oligodendrocyte Glycoprotein-IgG-Positive From Myelin Oligodendrocyte Glycoprotein-IgG-Negative Pediatric Acute Disseminated Encephalomyelitis in Northern China. Pediatric neurology. vol 156. 2024-05-23. PMID:38781724. |
novel genetic variants distinguishing myelin oligodendrocyte glycoprotein-igg-positive from myelin oligodendrocyte glycoprotein-igg-negative pediatric acute disseminated encephalomyelitis in northern china. |
2024-05-23 |
2024-05-27 |
Not clear |
| Yaqiong Cui, Bo Wu, Jinying Wu, Shuyue Zhang, Pan Guo, Jianbo Shu, Dong Li, Chunquan Ca. Novel Genetic Variants Distinguishing Myelin Oligodendrocyte Glycoprotein-IgG-Positive From Myelin Oligodendrocyte Glycoprotein-IgG-Negative Pediatric Acute Disseminated Encephalomyelitis in Northern China. Pediatric neurology. vol 156. 2024-05-23. PMID:38781724. |
acute disseminated encephalomyelitis (adem) is a common phenotype in children with myelin oligodendrocyte glycoprotein igg (mog-igg)-associated disease. |
2024-05-23 |
2024-05-27 |
Not clear |
| Pyone Pyone Soe, Mélanie Gaignage, Mohamed F Mandour, Etienne Marbaix, Jacques Van Snick, Jean-Paul Coutelie. Lactate Dehydrogenase-Elevating Virus Infection Inhibits MOG Peptide Presentation by CD11b+CD11c+ Dendritic Cells in a Mouse Model of Multiple Sclerosis. International journal of molecular sciences. vol 25. issue 9. 2024-05-11. PMID:38732169. |
infections with lactate dehydrogenase-elevating virus (ldv) protected mice from developing experimental autoimmune encephalomyelitis (eae), a mouse counterpart of ms. uninfected c57bl/6 mice immunized with the myelin oligodendrocyte glycoprotein peptide (mog35-55) experienced paralysis and lost weight at a greater rate than mice who had previously been infected with ldv. |
2024-05-11 |
2024-05-27 |
mouse |
| Michael M Poon, Kym I Lorrain, Karin J Stebbins, Geraldine C Edu, Alexander R Broadhead, Ariana O Lorenzana, Bryanna E Paulson, Christopher S Baccei, Jeffrey R Roppe, Thomas O Schrader, Lino J Valdez, Yifeng Xiong, Austin C Chen, Daniel S Lorrai. Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis. Scientific reports. vol 14. issue 1. 2024-05-08. PMID:38719983. |
direct dosing of pipe-791 in vivo increased oligodendrocyte number, and in the mouse experimental autoimmune encephalomyelitis (eae) model of ms, we observed that pipe-791 promoted myelination, reduced neuroinflammation, and restored visual evoked potential latencies (vep). |
2024-05-08 |
2024-05-27 |
mouse |
| Ramakrishna Prithviraj, Bidisha Banerjee, Ullas V Acharya, Muhammed Hafis, Sruthi Sashidhara. Clinico-radiologic Spectrum and Outcome of Pediatric Acquired Demyelinating Disorders of Central Nervous System: A Retrospective Indian Tertiary Care Hospital Cohort. Neuropediatrics. 2024-05-07. PMID:38641336. |
we describe clinico-radiologic spectrum, outcomes, and comparison of the groups: acute disseminated encephalomyelitis (adem), neuromyelitis optica spectrum disorder (nmosd), clinically isolated syndrome (cis), multiple sclerosis (ms), and myelin oligodendrocyte glycoprotein antibody-associated disorders (mogad). |
2024-05-07 |
2024-05-27 |
Not clear |
| Akash Virupakshaiah, Carson E Moseley, Steven Elicegui, Lee M Gerwitz, Collin M Spencer, Elizabeth George, Maulik Shah, Bruce A C Cree, Emmanuelle Waubant, Scott S Zamvi. Life-Threatening MOG Antibody-Associated Hemorrhagic ADEM With Elevated CSF IL-6. Neurology(R) neuroimmunology & neuroinflammation. vol 11. issue 4. 2024-04-17. PMID:38630950. |
acute disseminated encephalomyelitis (adem) is one characteristic manifestation of myelin oligodendrocyte glycoprotein antibody-associated disease (mogad). |
2024-04-17 |
2024-04-20 |
Not clear |
| S Jarius, M Ringelstein, K Schanda, K Ruprecht, M Korporal-Kuhnke, A Viehöver, M W Hümmert, P Schindler, V Endmayr, M Gastaldi, C Trebst, D Franciotta, O Aktas, R Höftberger, J Haas, L Komorowski, F Paul, M Reindl, B Wildeman. Improving the sensitivity of myelin oligodendrocyte glycoprotein-antibody testing: exclusive or predominant MOG-IgG3 seropositivity-a potential diagnostic pitfall in patients with MOG-EM/MOGAD. Journal of neurology. 2024-04-12. PMID:38609667. |
myelin oligodendrocyte glycoprotein antibody-associated encephalomyelitis (mog-em; also termed mog antibody-associated disease, mogad) is the most important differential diagnosis of both multiple sclerosis and neuromyelitis optica spectrum disorders. |
2024-04-12 |
2024-04-15 |
Not clear |
| Connor Frank, Hannah E Salapa, Kevin J H Allen, Michael C Levin, Wojciech Dawicki, Ekaterina Dadachov. Antibody-Mediated Depletion of Autoreactive T Lymphocytes through PD-1 Improves Disease Outcomes and Visualizes T Cell Activation in Experimental Autoimmune Encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). 2024-04-05. PMID:38578274. |
development of novel methods to target and deplete autoreactive t lymphocytes remains an attractive target for therapeutics for ms. we developed a programmed cell death 1 (pd-1)-targeted radiolabeled mab and assessed its ability to deplete activated pd-1+ t lymphocytes in vitro and its ability to reduce disease burden of the myelin oligodendrocyte glycoprotein 35-55 experimental autoimmune encephalomyelitis (eae) model in c57bl/6 mice. |
2024-04-05 |
2024-04-07 |
mouse |
| Andrey E Urusov, Kseniya S Aulova, Georgy A Nevinsk. Autoantibodies-Abzymes with Phosphatase Activity in Experimental Autoimmune Encephalomyelitis Mice. Molecules (Basel, Switzerland). vol 29. issue 6. 2024-03-28. PMID:38543019. |
however, the development of eae (experimental autoimmune encephalomyelitis simulating human ms) in c57bl/6 mice occurs due to the violation of bone marrow hematopoietic stem cell differentiation profiles, leading to the production of toxic for human autoantibody splitting mbp (myelin basic protein), mog (mouse oligodendrocyte glycoprotein), five histones, dna, and rna. |
2024-03-28 |
2024-03-30 |
mouse |
| Russell C Dale, Shekeeb S Mohamma. Movement disorders associated with pediatric encephalitis. Handbook of clinical neurology. vol 200. 2024-03-17. PMID:38494280. |
in addition, movement disorders can accompany acute disseminated encephalomyelitis with and without myelin oligodendrocyte glycoprotein antibodies. |
2024-03-17 |
2024-03-20 |
Not clear |
| Jia-Qi Wang, Qiang Li, Jia-Yi He, Fang Zhou, Zi-Hao Huang, Li-Bin Wang, Yuan Zhang, Xing L. Autophagy in Multiple Sclerosis: Phagocytosis and Autophagy of Oligodendrocyte Precursor Cells. Molecular neurobiology. 2024-02-16. PMID:38363533. |
finally, we obtained 9 autophagy genes with the highest correlation with ms, and further changes in these autophagy genes were verified in the experimental autoimmune encephalomyelitis (eae) model and oligodendrocyte precursor cells (opcs) engulfed myelin debris (md). |
2024-02-16 |
2024-02-18 |
Not clear |
| Philippe Antoine Bilodeau, Anastasia Vishnevetsky, Negar Molazadeh, Itay Lotan, Monique Anderson, Gabriela Romanow, Rebecca Salky, Brian C Healy, Marcelo Matiello, Tanuja Chitnis, Michael Lev. Effectiveness of immunotherapies in relapsing myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple sclerosis (Houndmills, Basingstoke, England). 2024-02-05. PMID:38314479. |
myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) can cause optic neuritis, transverse myelitis, or acute disseminated encephalomyelitis (adem). |
2024-02-05 |
2024-02-07 |
Not clear |
| Jihye Lee, Sungmoo Hong, Meejung Ahn, Jeongtae Kim, Changjong Moon, Hiroshi Matsuda, Akane Tanaka, Yoshihiro Nomura, Kyungsook Jung, Taekyun Shi. Eugenol alleviates the symptoms of experimental autoimmune encephalomyelitis in mice by suppressing inflammatory responses. International immunopharmacology. vol 128. 2024-01-12. PMID:38215654. |
we evaluated the therapeutic effects of eugenol on experimental autoimmune encephalomyelitis (eae), an established animal model of ms. eae was induced in c57bl/6 mice using the myelin oligodendrocyte glycoprotein (mog) |
2024-01-12 |
2024-01-15 |
mouse |
| Andrea Kwakowsky, Bhavya Chawdhary, Antonio de Souza, Emily Meyer, Andrew H Kaye, Colin R Green, Stanley S Stylli, Helen Danesh-Meye. Tonabersat Significantly Reduces Disease Progression in an Experimental Mouse Model of Multiple Sclerosis. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139284. |
the objective of the study was to evaluate if the cx43 hemichannel blocker, tonabersat, is effective in modulating the inflammatory response and reducing disability in the myelin oligodendrocyte glycoprotein 35-55-induced experimental autoimmune encephalomyelitis (mog |
2023-12-23 |
2023-12-25 |
mouse |
| Takashi Saito, Rieko Suzuki, Noboru Imai, Masahiro Serizaw. Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) Following Adenovirus Meningitis After First Delivery: Case Report and Literature Review. Cureus. vol 15. issue 11. 2023-12-07. PMID:38060760. |
myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) is a group of central nervous system (cns) demyelinating diseases caused by autoantibodies against myelin oligosaccharide protein (mog), a myelin sheath component protein, and present with a variety of symptoms, including optic neuritis, myelitis, acute disseminated encephalomyelitis (adem), brainstem encephalitis, and corticobasal encephalitis. |
2023-12-07 |
2023-12-17 |
Not clear |
| Kayla Martin, Priya Srikanth, Anand Kanwar, Julie Falardeau, David Pettersson, Vijayshree Yada. Clinical and radiographic features of a cohort of adult and pediatric subjects in the Pacific Northwest with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Multiple sclerosis and related disorders. vol 81. 2023-11-18. PMID:37979410. |
myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) is a newly described clinical entity comprised of isolated or recurrent attacks of optic neuritis, transverse myelitis, acute disseminated encephalomyelitis (adem), encephalitis, or seronegative nmosd. |
2023-11-18 |
2023-11-20 |
human |
| Mehmet Furkan Horat, Sefika Pinar Senol, Omer Bahceli, Meryem Temiz-Resitoglu, Seyhan Sahan-Firat, Serhan Sevim, Bahar Tuncta. Pro-inflammatory GPR75 and anti-apoptotic phospholipase signaling pathways contribute to the ameliorating effect of soluble epoxide hydrolase inhibition on chronic experimental autoimmune encephalomyelitis in mice. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 10. 2023-11-13. PMID:37953590. |
previously, we reported that treatment of mice with a seh-selective inhibitor, 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea; tppu), ameliorated chronic experimental autoimmune encephalomyelitis (eae) induced by myelin oligodendrocyte glycoprotein 35-55 peptide immunization followed by injection of pertussis toxin to mice via regulating pro-inflammatory and anti-inflammatory pathways in the central nervous system. |
2023-11-13 |
2023-11-20 |
mouse |
| Zhen Qian, Ke Zheng, Yanxuan Xu, Si Chen, Shaowan Chen, Jiajian Liang, Yingjie Cao, Tsz Kin Ng, Kunliang Qi. Longitudinal in vivo evaluation of retinal ganglion cell complex layer and dendrites in mice with experimental autoimmune encephalomyelitis. Experimental eye research. 2023-11-01. PMID:37913917. |
experimental autoimmune encephalomyelitis (eae), induced by the immunization of myelin oligodendrocyte glycoprotein (mog), is related to human mog antibody-associated disease (mogad). |
2023-11-01 |
2023-11-08 |
mouse |
| Emily A B Gilbert, Jessica Livingston, Emilio Garcia Flores, Monoleena Khan, Harini Kandavel, Cindi M Morshea. Metformin treatment reduces inflammation, dysmyelination and disease severity in a mouse model of multiple sclerosis, experimental autoimmune encephalomyelitis. Brain research. vol 1822. 2023-10-28. PMID:37890574. |
here, we investigated whether metformin administration could improve functional outcomes, modulate oligodendrocyte precursor cells (opcs), and reduce inflammation in a well-established mouse model of ms- experimental autoimmune encephalomyelitis (eae). |
2023-10-28 |
2023-11-08 |
mouse |