| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luting Yang, Chunqing Hu, Xiaowen Chen, Jie Zhang, Zhe Feng, Yanxin Xiao, Weitai He, Tingting Cui, Xin Zhang, Yang Yang, Yaling Zhang, Yaping Ya. Upregulated expression of ubiquitin ligase TRIM21 promotes PKM2 nuclear translocation and astrocyte activation in experimental autoimmune encephalomyelitis. eLife. vol 13. 2024-09-12. PMID:39264698. |
upregulated expression of ubiquitin ligase trim21 promotes pkm2 nuclear translocation and astrocyte activation in experimental autoimmune encephalomyelitis. |
2024-09-12 |
2024-09-14 |
mouse |
| Xiuli Lin, Yufeng Peng, Zhimei Guo, Wuhui He, Wenyuan Guo, Junmin Feng, Lin Lu, Qin Liu, Pingyi X. Short-chain fatty acids suppresses astrocyte activation by amplifying Trp-AhR-AQP4 signaling in experimental autoimmune encephalomyelitis mice. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-07-08. PMID:38976012. |
short-chain fatty acids suppresses astrocyte activation by amplifying trp-ahr-aqp4 signaling in experimental autoimmune encephalomyelitis mice. |
2024-07-08 |
2024-07-11 |
mouse |
| Mengya Jiao, Chenchen Wang, Xuhuan Tang, Chan Dai, Na Zhang, Anqi Fan, Zhigang Qian, Shiwang Liu, Feng Zhang, Bin Li, Yong Xu, Zheng Tan, Feili Gong, Yisheng Lu, Fang Zhen. Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis. Brain, behavior, and immunity. 2024-04-25. PMID:38663774. |
knockout of il-33 or its receptor st2 induced hippocampal astrocyte activation and depressive-like disorder in naive mice, as well as increased spinal cord astrocyte activation and polarization to a neurotoxic reactive subtype and aggravated passive experimental autoimmune encephalomyelitis (eae). |
2024-04-25 |
2024-04-28 |
mouse |
| Hong-Gyun Lee, Joseph M Rone, Zhaorong Li, Camilo Faust Akl, Seung Won Shin, Joon-Hyuk Lee, Lucas E Flausino, Florian Pernin, Chun-Cheih Chao, Kilian L Kleemann, Lena Srun, Tomer Illouz, Federico Giovannoni, Marc Charabati, Liliana M Sanmarco, Jessica E Kenison, Gavin Piester, Stephanie E J Zandee, Jack P Antel, Veit Rothhammer, Michael A Wheeler, Alexandre Prat, Iain C Clark, Francisco J Quintan. Disease-associated astrocyte epigenetic memory promotes CNS pathology. Nature. 2024-03-21. PMID:38509377. |
disease-associated astrocyte subsets contribute to the pathology of neurologic diseases, including multiple sclerosis and experimental autoimmune encephalomyelitis |
2024-03-21 |
2024-03-23 |
Not clear |
| Hong-Gyun Lee, Joseph M Rone, Zhaorong Li, Camilo Faust Akl, Seung Won Shin, Joon-Hyuk Lee, Lucas E Flausino, Florian Pernin, Chun-Cheih Chao, Kilian L Kleemann, Lena Srun, Tomer Illouz, Federico Giovannoni, Marc Charabati, Liliana M Sanmarco, Jessica E Kenison, Gavin Piester, Stephanie E J Zandee, Jack Antel, Veit Rothhammer, Michael A Wheeler, Alexandre Prat, Iain C Clark, Francisco J Quintan. Disease-associated astrocyte epigenetic memory promotes CNS pathology. bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260616. |
indeed, astrocyte subsets defined by specific transcriptional activation states contribute to the pathology of neurologic diseases, including multiple sclerosis (ms) and its pre-clinical model experimental autoimmune encephalomyelitis (eae) |
2024-01-23 |
2024-01-25 |
Not clear |
| Sergey Kalinin, Douglas L Feinstei. Astrocyte lipocalin-2 modestly effects disease severity in a mouse model of multiple sclerosis while reducing mature oligodendrocyte protein and mRNA expression. Neuroscience letters. 2023-09-25. PMID:37748675. |
we found that clinical scores in experimental autoimmune encephalomyelitis (eae) were modestly delayed in mice with conditional knockout of lcn2 from astrocytes, associated with a small decrease in astrocyte gfap expression. |
2023-09-25 |
2023-10-07 |
mouse |
| Julie J Ahn, Yusra Islam, Cheryl Clarkson-Paredes, Molly T Karl, Robert H Mille. B cell depletion modulates glial responses and enhances blood vessel integrity in a model of multiple sclerosis. Neurobiology of disease. 2023-09-14. PMID:37709209. |
here, we examine astrocyte and microglia responses to b cell depleting treatments in an animal model of ms, experimental autoimmune encephalomyelitis (eae). |
2023-09-14 |
2023-10-07 |
Not clear |
| Yoshiki Takai, Tatsuro Misu, Kazuo Fujihara, Masashi Aok. Pathology of myelin oligodendrocyte glycoprotein antibody-associated disease: a comparison with multiple sclerosis and aquaporin 4 antibody-positive neuromyelitis optica spectrum disorders. Frontiers in neurology. vol 14. 2023-08-07. PMID:37545724. |
mogad pathology is principally inflammatory demyelination without astrocyte destruction, characterized by perivenous demyelination previously reported in acute disseminated encephalomyelitis and by its fusion pattern localized in both the white and gray matter, but not by radially expanding confluent demyelination typically seen in multiple sclerosis (ms). |
2023-08-07 |
2023-08-14 |
human |
| Giuseppe Di Mauro, Roberta Amoriello, Neus Lozano, Alberto Carnasciali, Daniele Guasti, Maurizio Becucci, Giada Cellot, Kostas Kostarelos, Clara Ballerini, Laura Ballerin. Graphene Oxide Nanosheets Reduce Astrocyte Reactivity to Inflammation and Ameliorate Experimental Autoimmune Encephalomyelitis. ACS nano. 2023-01-24. PMID:36692902. |
graphene oxide nanosheets reduce astrocyte reactivity to inflammation and ameliorate experimental autoimmune encephalomyelitis. |
2023-01-24 |
2023-08-14 |
Not clear |
| Yumeng Ding, Liye Hu, Xiaotong Wang, Qingyu Sun, Tingting Hu, Jing Liu, Danmin Shen, Yurui Zhang, Wen Chen, Chao Wei, Meng Liu, Dianxin Liu, Peipei Wang, Chenguang Zhang, Jiannan Zhang, Qian Li, Fei Yan. The contribution of spinal dorsal horn astrocytes in neuropathic pain at the early stage of EAE. Neurobiology of disease. 2022-11-04. PMID:36332813. |
this study aims to explore astrocyte reactivity at different stages of the experimental autoimmune encephalomyelitis (eae) model, a mouse model of ms, and the role of astrocytes in the pain in the early stage of the eae. |
2022-11-04 |
2023-08-14 |
mouse |
| Lisa Allnoch, Eva Leitzen, Isabel Zdora, Wolfgang Baumgärtner, Florian Hansman. Astrocyte depletion alters extracellular matrix composition in the demyelinating phase of Theiler's murine encephalomyelitis. PloS one. vol 17. issue 6. 2022-06-17. PMID:35714111. |
astrocyte depletion alters extracellular matrix composition in the demyelinating phase of theiler's murine encephalomyelitis. |
2022-06-17 |
2023-08-14 |
mouse |
| Zhi-Yun Fan, Ya-Ping Chen, Li Chen, Xiao-Qin Zhang, Lin-Lin Chen, Bin Lu, Yan Wang, Wei Xu, Wei-Heng Xu, Jun-Ping Zhan. The matrine derivate MASM inhibits astrocyte reactivity and alleviates experimental autoimmune encephalomyelitis in mice. International immunopharmacology. vol 108. 2022-04-23. PMID:35461109. |
the matrine derivate masm inhibits astrocyte reactivity and alleviates experimental autoimmune encephalomyelitis in mice. |
2022-04-23 |
2023-08-13 |
mouse |
| Malte Borggrewe, Corien Grit, Ilia D Vainchtein, Nieske Brouwer, Evelyn M Wesseling, Jon D Laman, Bart J L Eggen, Susanne M Kooistra, Erik W G M Boddek. Regionally diverse astrocyte subtypes and their heterogeneous response to EAE. Glia. vol 69. issue 5. 2021-11-16. PMID:33332631. |
transcriptional differences between subtypes were also apparent in experimental autoimmune encephalomyelitis (eae) mice, where these astrocyte subtypes showed distinct responses. |
2021-11-16 |
2023-08-13 |
mouse |
| Alexandru Tatomir, Austin Beltrand, Vinh Nguyen, Dallas Boodhoo, Armugam Mekala, Cornelia Cudrici, Tudor C Badea, Dafin F Muresanu, Violeta Rus, Horea Ru. RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis. Frontiers in immunology. vol 11. 2021-06-23. PMID:33569054. |
we have previously shown that lack of response gene to complement 32 (rgc-32) alters astrocyte morphology in the spinal cord at the peak of experimental autoimmune encephalomyelitis (eae), suggesting a role for rgc-32 in astrocyte differentiation. |
2021-06-23 |
2023-08-13 |
mouse |
| Baohua Hou, Yahui Zhang, Peiyu Liang, Yuan He, Biwen Peng, Wanhong Liu, Song Han, Jun Yin, Xiaohua H. Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. Cell death & disease. vol 11. issue 5. 2021-04-07. PMID:32415059. |
inhibition of the nlrp3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. |
2021-04-07 |
2023-08-13 |
mouse |
| Sergey Kalinin, Gordon P Meares, Shao Xia Lin, Elizabeth A Pietruczyk, Gesine Saher, Lena Spieth, Klaus-Armin Nave, Anne I Boullerne, Sarah E Lutz, Etty N Benveniste, Douglas L Feinstei. Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. Glia. vol 68. issue 3. 2020-11-19. PMID:31664743. |
since astrocyte activation and metabolic function have important roles in regulating neuroinflammation and neuropathology, we examined the serine/threonine kinase lkb1 in astrocytes in a chronic experimental autoimmune encephalomyelitis mouse model of ms. to reduce lkb1, a heterozygous astrocyte-selective conditional knockout (het-cko) model was used. |
2020-11-19 |
2023-08-13 |
mouse |
| Katherine G Ravelli, Graziella D Santos, Nilton B Dos Santos, Carolina D Munhoz, Deborah Azzi-Nogueira, Ana Carolina Campos, Rosana L Pagano, Luiz R Britto, Marina S Hernande. Nox2-dependent Neuroinflammation in An EAE Model of Multiple Sclerosis. Translational neuroscience. vol 10. 2020-09-29. PMID:30984416. |
the purpose of this study was to investigate the effect of nox2 deletion on experimental autoimmune encephalomyelitis (eae) onset and severity, on astrocyte activation as well as on pro-inflammatory and anti-inflammatory cytokine induction in striatum and motor cortex. |
2020-09-29 |
2023-08-13 |
Not clear |
| Rhonda R Voskuhl, Noriko Itoh, Alessia Tassoni, Macy Akiyo Matsukawa, Emily Ren, Vincent Tse, Ellis Jang, Timothy Takazo Suen, Yuichiro Ito. Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 20. 2020-03-30. PMID:31040210. |
multiple sclerosis (ms) is multifocal, and regional differences in the astrocyte transcriptome occur in experimental autoimmune encephalomyelitis (eae), an ms model. |
2020-03-30 |
2023-08-13 |
mouse |
| Lisa Allnoch, Wolfgang Baumgärtner, Florian Hansman. Impact of Astrocyte Depletion upon Inflammation and Demyelination in a Murine Animal Model of Multiple Sclerosis. International journal of molecular sciences. vol 20. issue 16. 2020-01-15. PMID:31409036. |
the aim of this study was to investigate the impact of astrocyte depletion upon de- and remyelination, inflammation, axonal damage, and virus distribution in theiler`s murine encephalomyelitis (tme). |
2020-01-15 |
2023-08-13 |
Not clear |
| Xiaomei Liu, Qing Zhang, Weixiao Wang, Dongjiao Zuo, Jing Wang, Feng Zhou, Liping Niu, Xiangyang Li, Suping Qin, Yanbo Kou, Fanyun Kong, Wei Pan, Yugang Wang, Dianshuai Gao, Hong Sun, Jessica M Meves, Kuiyang Zheng, Renxian Tan. Analysis of Long Noncoding RNA and mRNA Expression Profiles in IL-9-Activated Astrocytes and EAE Mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 45. issue 5. 2018-05-14. PMID:29518786. |
astrocyte activation is involved in the pathogenesis of ms and experimental autoimmune encephalomyelitis (eae), an animal model of ms. |
2018-05-14 |
2023-08-13 |
mouse |