| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew Boyko, Benjamin F Gruenbaum, Anna Oleshko, Igor Merzlikin, Alexander Zlotni. Diet's Impact on Post-Traumatic Brain Injury Depression: Exploring Neurodegeneration, Chronic Blood-Brain Barrier Destruction, and Glutamate Neurotoxicity Mechanisms. Nutrients. vol 15. issue 21. 2023-11-14. PMID:37960334. |
diet's impact on post-traumatic brain injury depression: exploring neurodegeneration, chronic blood-brain barrier destruction, and glutamate neurotoxicity mechanisms. |
2023-11-14 |
2023-11-20 |
Not clear |
| Matthew Boyko, Benjamin F Gruenbaum, Anna Oleshko, Igor Merzlikin, Alexander Zlotni. Diet's Impact on Post-Traumatic Brain Injury Depression: Exploring Neurodegeneration, Chronic Blood-Brain Barrier Destruction, and Glutamate Neurotoxicity Mechanisms. Nutrients. vol 15. issue 21. 2023-11-14. PMID:37960334. |
the purpose of this article is to evaluate the involvement of dietary glutamate in the development of depression after tbi. |
2023-11-14 |
2023-11-20 |
Not clear |
| Matthew Boyko, Benjamin F Gruenbaum, Anna Oleshko, Igor Merzlikin, Alexander Zlotni. Diet's Impact on Post-Traumatic Brain Injury Depression: Exploring Neurodegeneration, Chronic Blood-Brain Barrier Destruction, and Glutamate Neurotoxicity Mechanisms. Nutrients. vol 15. issue 21. 2023-11-14. PMID:37960334. |
we specifically explored these effects in the context of chronic bbb damage after tbi, which may initiate neurodegeneration and subsequently have an impact on depression through the mechanism of chronic glutamate neurotoxicity. |
2023-11-14 |
2023-11-20 |
Not clear |
| Patrycja Pa\\xc5\\x84czyszyn-Trzewik, Ewelina Czechowska, Katarzyna Stachowicz, Magdalena Sowa-Ku\\xc4\\x87m. The Importance of \\xce\\xb1-Klotho in Depression and Cognitive Impairment and Its Connection to Glutamate Neurotransmission-An Up-to-Date Review. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37894946. |
the importance of \xce\xb1-klotho in depression and cognitive impairment and its connection to glutamate neurotransmission-an up-to-date review. |
2023-10-30 |
2023-11-08 |
Not clear |
| Lan Lei, Ya-Ting Wang, Die Hu, Cong Gai, Yi Zhan. Astroglial Connexin 43-Mediated Gap Junctions and Hemichannels: Potential Antidepressant Mechanisms and the Link to Neuroinflammation. Cellular and molecular neurobiology. 2023-10-24. PMID:37875763. |
the effect of cx43 on neuroinflammation-related depression involving inflammatory cytokines, glutamate excitotoxicity, and hpa axis dysregulation. |
2023-10-24 |
2023-11-08 |
Not clear |
| Gehua Wen, Xiaoni Zhan, Xiaoming Xu, Xi Xia, Shukun Jiang, Xinghua Ren, Weishu Ren, Haoyang Lou, Lei Lu, Anca Hermenean, Jun Yao, Lina Gao, Baoman Li, Yan Lu, Xu W. Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model. Molecular neurobiology. 2023-10-15. PMID:37840071. |
depression is associated with elevated levels of glutamate and astrocyte loss in the brain; the exploration of the relationships between ketamine's antidepressant effect and astrocytes has drawn great attention. |
2023-10-15 |
2023-11-08 |
mouse |
| Nazanin Hatami Bavarsad, Shokufeh Bagheri, Masoumeh Kourosh-Arami, Alireza Komak. Aromatherapy for the brain: Lavender's healing effect on epilepsy, depression, anxiety, migraine, and Alzheimer's disease: A review article. Heliyon. vol 9. issue 8. 2023-08-09. PMID:37554839. |
it improves depression by regulating glutamate receptors and inhibiting calcium channels and serotonergic factors, such as sert. |
2023-08-09 |
2023-08-16 |
Not clear |
| G\\xc3\\xbclin \\xc3\\x96zdamar \\xc3\\x9cnal, Gamze Erk\\xc4\\xb1l\\xc4\\xb1n\\xc3\\xa7, Kuya\\xc5\\x9f Hekimler \\xc3\\x96zt\\xc3\\xbcrk, Duygu Kumbul Dogu\\xc3\\xa7, \\xc3\\x96zlem \\xc3\\x96zme. The beneficial effects of vortioxetine on BDNF, CREB, S100B, \\xce\\xb2 amyloid, and glutamate NR2b receptors in chronic unpredictable mild stress model of depression. Psychopharmacology. 2023-08-09. PMID:37555927. |
the beneficial effects of vortioxetine on bdnf, creb, s100b, \xce\xb2 amyloid, and glutamate nr2b receptors in chronic unpredictable mild stress model of depression. |
2023-08-09 |
2023-08-16 |
Not clear |
| Hao Li, Xunrong Luo, Kai Qi, Yijie Lv, Junnan Kan, Changfeng Yang, Xiaoqian Lin, Jin Tao, Wei Zhang, Yan Liu, Kang Rong, Ailing Wang, Zhongde Jiang, Xianglin L. Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model. Journal of magnetic resonance imaging : JMRI. 2023-07-27. PMID:37496196. |
glutamate chemical exchange saturation transfer (glucest) mri to evaluate the rapid antidepressant effects of ketamine in the hippocampus of rat depression model. |
2023-07-27 |
2023-08-14 |
rat |
| Hao Li, Xunrong Luo, Kai Qi, Yijie Lv, Junnan Kan, Changfeng Yang, Xiaoqian Lin, Jin Tao, Wei Zhang, Yan Liu, Kang Rong, Ailing Wang, Zhongde Jiang, Xianglin L. Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model. Journal of magnetic resonance imaging : JMRI. 2023-07-27. PMID:37496196. |
ketamine's effects in a rat depression model have not previously been well explored using glutamate chemical exchange saturation transfer (glucest). |
2023-07-27 |
2023-08-14 |
rat |
| Erkan G\\xc3\\xb6k\\xc3\\xa7. Editorial for "Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model". Journal of magnetic resonance imaging : JMRI. 2023-07-27. PMID:37496402. |
editorial for "glutamate chemical exchange saturation transfer (glucest) mri to evaluate the rapid antidepressant effects of ketamine in the hippocampus of rat depression model". |
2023-07-27 |
2023-08-14 |
rat |
| Mustafa Q Hameed, Benjamin Hui, Rui Lin, Paul C MacMullin, Andres Pascual-Leone, Sheryl Anne D Vermudez, Alexander Rotenber. Depressed glutamate transporter 1 expression in a mouse model of Dravet syndrome. Annals of clinical and translational neurology. 2023-07-14. PMID:37452008. |
here, we demonstrate reduced expression of the rodent glutamate transporter type 1 (glt-1) in a ds mouse model, and in wild type mouse strains where scn1a haploinsufficiency is most likely to cause epilepsy, indicating that glt-1 depression may play a role in ds seizures. |
2023-07-14 |
2023-08-14 |
mouse |
| Jeongseop Kim, Tae-Eun Kim, Seung-Hwan Lee, Ja Wook Ko. The Role of Glutamate Underlying Treatment-resistant Depression. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 21. issue 3. 2023-07-10. PMID:37424412. |
the role of glutamate underlying treatment-resistant depression. |
2023-07-10 |
2023-08-14 |
Not clear |
| Carla Fonseca, Miren Ettcheto, Joana Bicker, Maria Jos\\xc3\\xa9 Fernandes, Am\\xc3\\xadlcar Falc\\xc3\\xa3o, Antoni Camins, Ana Fortun. Under the umbrella of depression and Alzheimer's disease physiopathology: can cannabinoids be a dual-pleiotropic therapy? Ageing research reviews. 2023-07-06. PMID:37414155. |
besides the well-known imbalance of neurotransmitter levels, including serotonin, noradrenaline, dopamine and glutamate, recent scientific evidence highlights aberrant spine density, neuroinflammation, dysregulation of neurotrophic factor levels and formation of amyloid beta (a\xce\xb2) peptides, as the main physiopathological mechanisms compromised in depression and ad. |
2023-07-06 |
2023-08-14 |
Not clear |
| Na Ji, Mengzhu Lei, Yating Chen, Shaowen Tian, Chuanyu Li, Bo Zhan. How Oxidative Stress Induces Depression? ASN neuro. vol 15. 2023-06-18. PMID:37331994. |
fully uncovering the underlying mechanisms of os-induced depression is the first step towards the avenue, thus we summarize and expound possible downstream pathways of os, including mitochondrial impairment and related atp deficiency, neuroinflammation, central glutamate excitotoxicity, brain-derived neurotrophic factor/tyrosine receptor kinase b dysfunction and serotonin deficiency, the microbiota-gut-brain axis disturbance and hypothalamic-pituitary-adrenocortical axis dysregulation. |
2023-06-18 |
2023-08-14 |
Not clear |
| Simin Ye, Yanqiang Han, Zhiyun Wei, Jinjin L. Binding Affinity and Mechanisms of Potential Antidepressants Targeting Human NMDA Receptors. Molecules (Basel, Switzerland). vol 28. issue 11. 2023-06-11. PMID:37298821. |
n-methyl-d-aspartic acid (nmda) is an ionotropic glutamate receptor that plays an important role in learning and memory processes and its tmd region is considered as a potential target to treat depression. |
2023-06-11 |
2023-08-14 |
human |
| Erika Vazquez-Juarez, Ipsit Srivastava, Maria Lindsko. The effect of ketamine on synaptic mistuning induced by impaired glutamate reuptake. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-10. PMID:37301901. |
moreover, a similar reduced threshold for ltp was observed in a rat model of depression with decreased levels of glutamate transporters. |
2023-06-10 |
2023-08-14 |
rat |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
in addition, oxt induces cell-type-specific depression and potentiation of drn glutamate synapses by two retrograde lipid messengers, 2-arachidonoylglycerol (2-ag) and arachidonic acid (aa), respectively. |
2023-05-30 |
2023-08-14 |
Not clear |
| Ta\\xc3\\xads da Silva Teixeira Rech, Dianer Nornberg Strelow, Let\\xc3\\xadcia Devantier Kr\\xc3\\xbcger, Jos\\xc3\\xa9 Sebasti\\xc3\\xa3o Santos Neto, Gustavo Bierhals Bl\\xc3\\xb6dorn, Diego Alves, C\\xc3\\xa9sar Augusto Br\\xc3\\xbcning, Cristiani Folharini Bortolatt. Pharmacological evidence for glutamatergic pathway involvement in the antidepressant-like effects of 2-phenyl-3-(phenylselanyl)benzofuran in male Swiss mice. Naunyn-Schmiedeberg's archives of pharmacology. 2023-05-09. PMID:37160481. |
depression is a multifactorial and heterogeneous disease with several neurobiological mechanisms underlying its pathophysiology, including dysfunctional glutamatergic neurotransmission, which makes the exploration of the glutamate pathway an interesting strategy for developing novel rapid-acting antidepressant treatments. |
2023-05-09 |
2023-08-14 |
mouse |
| Dan Wang, Yao Gao, Yaojun Li, Yu Zhao, Xinzhe Du, Xinrong Li, Yu Zhang, Sha Liu, Yong X. Plasma metabolomics and network pharmacology identified glutamate, glutamine, and arginine as biomarkers of depression under Shuganjieyu capsule treatment. Journal of pharmaceutical and biomedical analysis. vol 232. 2023-05-05. PMID:37146496. |
plasma metabolomics and network pharmacology identified glutamate, glutamine, and arginine as biomarkers of depression under shuganjieyu capsule treatment. |
2023-05-05 |
2023-08-14 |
Not clear |