| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Zhang, Mingqi Qiao, Dongmei Gao, Jieqiong Wang, Chunyan Sun, Ya Sun, Yang Zhang, Huayuan Liu, Zhen Zhang, Mingzhou Ga. Shuyu capsule alleviates premenstrual depression via allopregnanolone metabolic pathway targeting GABA (A) receptors \\xce\\xb4 subunit in the hippocampus. Asian journal of psychiatry. vol 90. 2023-10-28. PMID:37898099. |
to reveal the exact changes of allopregnanolone-mediated \xce\xb3-aminobutyric acid a receptor pathways and its specific therapeutic targets by shuyu capsule treating premenstrual depression, female wistar rat models of premenstrual depression was established by forced swimming test (fst). |
2023-10-28 |
2023-11-08 |
rat |
| Sadia Tabassam Arif, Muhammad Ayub Khan, Shahiq Uz Zaman, Hafiz Shoaib Sarwar, Abida Raza, Muhammad Sarfraz, Yousef A Bin Jardan, Muhammad Umair Amin, Muhammad Farhan Sohai. Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice. Pharmaceuticals (Basel, Switzerland). vol 16. issue 9. 2023-09-28. PMID:37765028. |
an improved antidepressant effect of lsp-nlcs on lps-induced depression showed an increase in swimming time (237 \xc2\xb1 51 s) and struggling time (226 \xc2\xb1 15 s) with a reduction in floating (123 \xc2\xb1 51 s) and immobility time (134 \xc2\xb1 15 s) in fst and tst. |
2023-09-28 |
2023-10-07 |
mouse |
| Hanan H Ahmed, Reham M Essam, Muhammed F El-Yamany, Kawkab A Ahmed, Ayman E El-Saha. Unleashing lactoferrin's antidepressant potential through the PI3K/Akt/mTOR pathway in chronic restraint stress rats. Food & function. 2023-09-28. PMID:37767889. |
depression was evidenced by a reduced grooming time in the splash test and an increased immobility time in the tail suspension test (tst) and forced swimming test (fst). |
2023-09-28 |
2023-10-07 |
rat |
| Xin-Yuan Wu, Xiang Jin, Xiao-Ming Sheng, Yan Fan, Wei Gua. miR-204-5p plays a critical role in the pathogenesis of depression and anti-depression action of Venlafaxine in the hippocampus of mice. Current medicinal chemistry. 2023-06-26. PMID:37357509. |
method a chronic social defeat stress (csds) was initially adopted for establishing a mice model of depression in this research and depression-like behaviors were evaluated by a series of behavioral experiments including the sucrose preference test (spt), the tail suspension test (tst), the forced swim test (fst) and the social interaction test (sit). |
2023-06-26 |
2023-08-14 |
mouse |
| Mariam D Oduola-Akande, Ismail O Ishola, Taiwo G Olubodun-Obadun, Adeola J Akande, Olufunmilayo O Adeyem. Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice. Neurotoxicity research. 2023-01-27. PMID:36705862. |
effect of glimepiride on motor activities were appraised with the use of open-field test and rotarod performance while non-motor activity was evaluated using force swim test (fst; depression) and y-maze test (working memory). |
2023-01-27 |
2023-08-14 |
mouse |
| Yan Zhuang, Runying Zeng, Xiao Liu, Longhe Yang, Zhuhua Cha. Neoagaro-Oligosaccharides Ameliorate Chronic Restraint Stress-Induced Depression by Increasing 5-HT and BDNF in the Brain and Remodeling the Gut Microbiota of Mice. Marine drugs. vol 20. issue 11. 2022-11-24. PMID:36422003. |
anxiety and depression behaviors were assessed by open field tests (oft) and forced swimming tests (fst), while interleukin 18 (il-18), 5-hydroxytryptamine (5-ht) and brain-derived neurotrophic factor (bdnf) were the molecular biomarkers of depression. |
2022-11-24 |
2023-08-14 |
mouse |
| Satya Kumar Avula, Ajmal Khan, Sobia Ahsan Halim, Najeeb Ur Rehman, Nasiara Karim, Imran Khan, Rene Csuk, Biswanath Das, Ahmed Al-Harras. Synthesis and antidepressant-like effects of new 5-epi-incensole and 5-epi- incensole acetate in chronic unpredictable mild stress model of depression; behavioural and biochemical correlates. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-11-22. PMID:36411640. |
the resulting compounds were evaluated for their ability to ameliorate depressive symptoms in forced swim test (fst) and tail suspension test (tst) in chronic unpredictable mild stress (cums) induced depression paradigm. |
2022-11-22 |
2023-08-14 |
mouse |
| Zifan Ding, Longfei D. Swimming exercise ameliorates depressive-like behavior by anti-inflammation activity, rebalancing gut Escherichia coli and Lactobacilli. Brain research. 2022-10-04. PMID:36195262. |
major depressive disorder (mdd) is a common mental disease with high morbidity, recurrence and mortality and is a serious global health problem.aerobic exercise produces beneficial effects on depression and associated comorbidities.swimming exercise with high motor complexity may be particularly beneficial for patients with depression.we hypothesized that swimming exercise improves various types of depression-like behaviors and these effects are related to improved immune and inflammatory response by regulating microbiota-gut-brain axis.we established the lipopolysaccharides (lps)/ chronic unpredictable stress (cus) mice model of depression.the forced swimming test (fst) and tail suspension test (tst) were used as predictive animal models of antidepressant-like activity.swimming exercise significantly decreased the duration of immobility in fst and tst.we found that swimming exercise could significantly decrease the levels of pro-inflammatory cytokines in the central nervous system (cns). |
2022-10-04 |
2023-08-14 |
mouse |
| Lin-Sheng Shi, Chun-Hui Ji, Wen-Qian Tang, Yue Liu, Wei Zhang, Wei Gua. Hippocampal miR-124 participates in the pathogenesis of depression via regulating the expression of BDNF in a Chronic Social Defeat Stress model of depression. Current neurovascular research. 2022-07-15. PMID:35838216. |
methods in the study, we used the forced swim test (fst), the tail suspension test (tst), and a chronic social defeat stress (csds) mice model of depression. |
2022-07-15 |
2023-08-14 |
mouse |
| Yan Wang, Sixu Zhou, Xujiao Song, Shanshan Ding, Baogui Wang, Jiangfeng Wen, Chunlin Che. Study on Antidepressant Effect and Mechanism of Crocin Mediated by the mTOR Signaling Pathway. Neurochemical research. 2022-07-08. PMID:35804209. |
the depression model was established by chronic unpredictable mild stress (cums), and its antidepressant effect was estimated by open field test (oft), forced swimming test (fst), and tail suspension test (tst). |
2022-07-08 |
2023-08-14 |
mouse |
| Najeeb Ur Rehman, Sulaiman Al-Shidhani, Nasiara Karim, Ajmal Khan, Imran Khan, Sobia Ahsan Halim, Sajid Khan Sadozai, Satya Kumar Avula, Rene Csuk, Ahmed Al-Harras. Incensole derivatives from frankincense: Isolation, enhancement, synthetic modification, and a plausible mechanism of their anti-depression activity. Bioorganic chemistry. vol 126. 2022-06-07. PMID:35671644. |
demonstrated promising anti-depression activities in classical mouse models of depression of fst and tst. |
2022-06-07 |
2023-08-14 |
mouse |
| Xin Liang, Jing Tang, Ying-Qiang Qi, Yan-Min Luo, Chun-Mao Yang, Xiao-Yun Dou, Lin Jiang, Qian Xiao, Lei Zhang, Feng-Lei Chao, Chun-Ni Zhou, Yong Tan. Exercise more efficiently regulates the maturation of newborn neurons and synaptic plasticity than fluoxetine in a CUS-induced depression mouse model. Experimental neurology. 2022-05-07. PMID:35525307. |
the sucrose preference test (spt), the forced swimming test (fst), the tail suspension test (tst), immunohistochemistry, immunofluorescence and stereological analyses were used to clarify the difference in therapeutic efficacy and mechanism between exercise and fluoxetine in the treatment of depression. |
2022-05-07 |
2023-08-13 |
mouse |
| Bryan G Nadeau, Elliott G Marchant, Shimon Amir, Ralph E Mistlberge. Thermoregulatory significance of immobility in the forced swim test. Physiology & behavior. 2022-01-22. PMID:35065081. |
the forced swim test (fst) is a widely used animal model of depression and antidepressant drug screen. |
2022-01-22 |
2023-08-13 |
rat |
| Bryan G Nadeau, Elliott G Marchant, Shimon Amir, Ralph E Mistlberge. Thermoregulatory significance of immobility in the forced swim test. Physiology & behavior. 2022-01-22. PMID:35065081. |
immobility is said to reflect a state of lowered mood or "behavioral despair", but the validity of the fst as a model of depression has been questioned. |
2022-01-22 |
2023-08-13 |
rat |
| Farajollah Jafari, Mahdi Goudarzvand, Ramin Hajikhani, Mostafa Qorbani, Jalal Solat. Pycnogenol ameliorates motor function and gene expressions of NF-\\xc6\\x99B and Nrf2 in a 6-hydroxydopamine-induced experimental model of Parkinson's disease in male NMRI mice. Naunyn-Schmiedeberg's archives of pharmacology. 2022-01-13. PMID:35024909. |
seven days after parkinson's model induction, the apomorphine test, the degree of catalepsy by bar test, the duration of immobility (depression) by forced swimming test (fst) were measured. |
2022-01-13 |
2023-08-13 |
mouse |
| Hikmet Gumus, Rabia Ilgin, Basar Koc, Oguz Yuksel, Servet Kizildag, Guven Guvendi, Asli Karakilic, Sevim Kandis, Ferda Hosgorler, Mehmet Ates, Hasan Alacam, Nazan Uysa. A combination of ketogenic diet and voluntary exercise ameliorates anxiety and depression-like behaviors in Balb/c mice. Neuroscience letters. 2022-01-06. PMID:34990761. |
there was a negative correlation between bhb and the time spent in the closed arms of elevated plus maze (epm) or the time spent in periphery walls of open field test (oft) and the immobility time in forced swim test (fst) which all of them are indicators of low depression and anxiety levels. |
2022-01-06 |
2023-08-13 |
mouse |
| Hui-Zhen Li, Ning-Xi Zeng, Kai-Ge Liu, Wu-Long Luo, Wen-Jun Lu, Li-Li W. [Preliminary study on cerebrospinal fluid proteomics of Erxian Decoction against neurogenesis impairment in late-onset depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 23. 2021-12-24. PMID:34951250. |
behavioral tests showed that sucrose consumption in spt, total traveling distance in oft, and times of crossing the platform in mwmt were all reduced(p<0.01) and the immobility time in fst was prolonged(p<0.01) in the lod group compared with those in the aged group, suggesting that lod rats had developed depression symptoms such as anhedonia, decreased locomotor activity ability, and cognitive dysfunction. |
2021-12-24 |
2023-08-13 |
rat |
| Arnab Nandi, Garima Virmani, Aatmika Barve, Swananda Marath. DBscorer: An Open-Source Software for Automated Accurate Analysis of Rodent Behavior in Forced Swim Test and Tail Suspension Test. eNeuro. vol 8. issue 6. 2021-12-11. PMID:34625460. |
here, we describe the development of depression behavior scorer (dbscorer), an open-source program installable on windows, with an intuitive graphical user interface (gui), that helps in accurate quantification of immobility behavior in fst and tst from video analysis. |
2021-12-11 |
2023-08-13 |
Not clear |
| Shun Aoki, Satoshi Deyama, Rinako Sugie, Kohei Ishimura, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaned. The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34801580. |
(1\xc2\xa0ng) and intra-mpfc (50\xc2\xa0pg/side) infusions of rve1 in the repeated psl-induced depression mouse model using the oft and fst after 5- and 6-day psl treatments, respectively. |
2021-12-11 |
2023-08-13 |
mouse |
| Amalia D\\xc3\\xa1vila-Hern\\xc3\\xa1ndez, Roberto Gonz\\xc3\\xa1lez-Gonz\\xc3\\xa1lez, Sonia Guzm\\xc3\\xa1n-Vel\\xc3\\xa1zquez, Olivia Tania Hern\\xc3\\xa1ndez Hern\\xc3\\xa1ndez, Sergio R Zamudio, Luc\\xc3\\xada Mart\\xc3\\xadnez-Mot. Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats. Brain research bulletin. vol 173. 2021-12-09. PMID:33991609. |
post-weaning social isolated rodents exhibit pathophysiological changes associated with depression including adrenal axis hyperactivity, gonadal hormone level disturbances, molecular alterations in hippocampus, and immobility behavior in the forced swimming test (fst). |
2021-12-09 |
2023-08-13 |
rat |