| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leandro Machado Oliveira, Flávio Fernando Demarco, Fabrício Batistin Zanatt. Educational inequalities and alcohol-related consequences in Brazil. Alcohol and alcoholism (Oxford, Oxfordshire). vol 59. issue 3. 2024-05-02. PMID:38695263. |
this study aimed to test whether the alcohol harm paradox (ahp) is observed in brazil by investigating (i) the association between educational attainment and alcohol-related consequences (arc) and (ii) the contribution of average alcohol volume consumed (avc), past-month heavy episodic drinking (hed), smoking, body mass index (bmi), and depression in accounting for the disparities in arc. |
2024-05-02 |
2024-05-04 |
Not clear |
| Wenqi Qiu, Qian Wu, Kaiwen Zhang, Xiaoli Da, Kairui Tang, Naijun Yuan, Lijuan Deng, Mansi Wu, Ying Zhang, Jiangyan Quan, Qingyu Ma, Xiaojuan Li, Jiaxu Che. Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus. BMC complementary medicine and therapies. vol 23. issue 1. 2023-04-12. PMID:37046230. |
leptin receptor (lepr) regulates energy expenditure and depression by mediating the action of leptin on the arc. |
2023-04-12 |
2023-08-14 |
rat |
| Jonah Meyerhoff, Rachel Kornfield, David C Mohr, Madhu Redd. Meeting Young Adults' Social Support Needs across the Health Behavior Change Journey: Implications for Digital Mental Health Tools. Proceedings of the ACM on human-computer interaction. vol 6. issue CSCW2. 2022-11-17. PMID:36387059. |
we recruited a sample of young adults with depression who were seeking information about their symptoms online to participate in an asynchronous remote community (arc) elicitation workshop. |
2022-11-17 |
2023-08-14 |
human |
| Yunchao Shu, Sune G Nielsen, Veronique Le Roux, Gerhard Wörner, Jerzy Blusztajn, Maureen Aur. Sources of dehydration fluids underneath the Kamchatka arc. Nature communications. vol 13. issue 1. 2022-08-02. PMID:35918359. |
in succession, serpentine (<100 km depth), lawsonite (100-250 km depth) and phengite (>250 km depth) break down and produce fluids that contribute to arc magmatism at the eastern volcanic front (evf), central kamchatka depression (ckd), and sredinny ridge (sr), respectively. |
2022-08-02 |
2023-08-14 |
Not clear |
| Shiqian Yu, Gaohua Wang, Baozhen Yao, Ling Xiao, Hu Tu. Arc and Homer1 are involved in comorbid epilepsy and depression: A microarray data analysis. Epilepsy & behavior : E&B. vol 132. 2022-06-06. PMID:35665606. |
arc and homer1 are involved in comorbid epilepsy and depression: a microarray data analysis. |
2022-06-06 |
2023-08-14 |
Not clear |
| Stephen C Gammi. Evaluation of animal model congruence to human depression based on large-scale gene expression patterns of the CNS. Scientific reports. vol 12. issue 1. 2022-01-08. PMID:34997033. |
in most of the top models, a consistent dysregulation of map kinase pathway was identified and the genes nr4a1, bdnf, arc, egr2, and pde7b were consistently downregulated as in humans with depression. |
2022-01-08 |
2023-08-13 |
human |
| Malte Bieler, Suleman Hussain, Elise S B Daaland, Martine M Mirrione, Fritz A Henn, Svend Davange. Changes in concentrations of NMDA receptor subunit GluN2B, Arc and syntaxin-1 in dorsal hippocampus Schaffer collateral synapses in a rat learned helplessness model of depression. The Journal of comparative neurology. vol 529. issue 12. 2021-11-01. PMID:33843051. |
changes in concentrations of nmda receptor subunit glun2b, arc and syntaxin-1 in dorsal hippocampus schaffer collateral synapses in a rat learned helplessness model of depression. |
2021-11-01 |
2023-08-13 |
rat |
| Xing Fang, Shujun Jiang, Jiangong Wang, Yu Bai, Chung Sub Kim, David Blake, Neal L Weintraub, Yun Lei, Xin-Yun L. Chronic unpredictable stress induces depression-related behaviors by suppressing AgRP neuron activity. Molecular psychiatry. vol 26. issue 6. 2021-10-11. PMID:33432188. |
our findings suggest that agrp neurons in the arc are a key component of neural circuitry involved in mediating depression-related behaviors and that increasing agrp neuronal activity coule be a novel and effective treatment for depression. |
2021-10-11 |
2023-08-13 |
mouse |
| M C Vishnu Shandilya, Akash Gauta. Hippocampal Arc Induces Decay of Object Recognition Memory in Male Mice. Neuroscience. vol 431. 2021-05-14. PMID:32087261. |
activity-regulated cytoskeleton-associated (arc) gene is one of the effector neuronal immediate early genes (ieg) that is rapidly upregulated after neuronal activation and is involved in synaptic long-term potentiation and depression. |
2021-05-14 |
2023-08-13 |
mouse |
| Ioanna Mylona, Georgios Floros, Maria Dermenoudi, Nikolaos Ziakas, Ioannis Tsinopoulo. A comparative study of depressive symptomatology among cataract and age-related macular degeneration patients with impaired vision. Psychology, health & medicine. vol 25. issue 9. 2021-04-19. PMID:32064912. |
vision impairment remains an important cause of disability with the leading being age-related cataract (arc) and age-related macular degeneration (armd) with depression symptoms often reported in vision impairment. |
2021-04-19 |
2023-08-13 |
Not clear |
| Yuru Du, Wenjing Li, Yiming Li, Juxiang Yang, Xinhao Wang, Shuo Yin, Xi Wang, Omar Israel Velez de-la-Paz, Yuan Gao, Haiying Chen, Xi Yin, Haishui Sh. Repeated arctigenin treatment produces antidepressant- and anxiolytic-like effects in mice. Brain research bulletin. vol 146. 2020-03-10. PMID:30597190. |
results showed that chronic arc administration produces antidepressant- and anxiolytic-like effects, which provides direct evidence for the first time that arc may be a novel strategy for the treatment of depression and even stress-related disorders. |
2020-03-10 |
2023-08-13 |
mouse |
| Yuru Du, Wenjing Li, Yiming Li, Juxiang Yang, Xinhao Wang, Shuo Yin, Xi Wang, Omar Israel Velez de-la-Paz, Yuan Gao, Haiying Chen, Xi Yin, Haishui Sh. Repeated arctigenin treatment produces antidepressant- and anxiolytic-like effects in mice. Brain research bulletin. vol 146. 2020-03-10. PMID:30597190. |
the present data supports further exploration for developing arc administration as a novel therapeutic strategy for depression and even stress-related disorders. |
2020-03-10 |
2023-08-13 |
mouse |
| Wenchi Zhang, Yang-An Chuang, Youn Na, Zengyou Ye, Liuqing Yang, Raozhou Lin, Jiechao Zhou, Jing Wu, Jessica Qiu, Alena Savonenko, Daniel J Leahy, Richard Huganir, David J Linden, Paul F Worle. Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation. Molecular cell. vol 75. issue 1. 2020-01-13. PMID:31151856. |
mutant arc that cannot be phosphorylated by camkii enhances metabotropic receptor-dependent depression in the hippocampus but does not alter baseline synaptic transmission or long-term potentiation. |
2020-01-13 |
2023-08-13 |
Not clear |
| Oleksii Nikolaienko, Sudarshan Patil, Maria Steene Eriksen, Clive R Bramha. Arc protein: a flexible hub for synaptic plasticity and cognition. Seminars in cell & developmental biology. vol 77. 2018-12-11. PMID:28890419. |
neuronal activity-induced expression of the immediate early protein, arc, is critical for long-term potentiation and depression of synaptic transmission, homeostatic synaptic scaling, and adaptive functions such as long-term memory formation. |
2018-12-11 |
2023-08-13 |
Not clear |
| Julia R Wilkerson, Joseph P Albanesi, Kimberly M Hube. Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease. Seminars in cell & developmental biology. vol 77. 2018-12-11. PMID:28969983. |
importantly, ca1 neurons with experience-induced arc mrna are susceptible, or primed for mglur-induced long-term synaptic depression (mglur-ltd). |
2018-12-11 |
2023-08-13 |
human |
| Irina Epstein, Steven Finkbeine. The Arc of cognition: Signaling cascades regulating Arc and implications for cognitive function and disease. Seminars in cell & developmental biology. vol 77. 2018-12-11. PMID:29559111. |
the activity-regulated cytoskeletal (arc) gene is implicated in numerous synaptic plasticity paradigms, including long-term potentiation and depression and homeostatic plasticity, and is critical for consolidating memory. |
2018-12-11 |
2023-08-13 |
Not clear |
| Sami El-Boustani, Jacque P K Ip, Vincent Breton-Provencher, Graham W Knott, Hiroyuki Okuno, Haruhiko Bito, Mriganka Su. Locally coordinated synaptic plasticity of visual cortex neurons in vivo. Science (New York, N.Y.). vol 360. issue 6395. 2018-08-22. PMID:29930137. |
the locally coordinated potentiation and depression of spines involves prominent ampa receptor redistribution via targeted expression of the immediate early gene product arc. |
2018-08-22 |
2023-08-13 |
mouse |
| Jennifer L Steiner, Megan E Bardgett, Lawrence Wolfgang, Charles H Lang, Sean D Stocke. Glucocorticoids attenuate the central sympathoexcitatory actions of insulin. Journal of neurophysiology. vol 112. issue 10. 2015-10-19. PMID:25185805. |
the lack of a sympathetic response to insulin cannot be attributed to a generalized depression of sympathetic function or inactivation of arc neurons as electrical activation of sciatic afferents or arc injection of gabazine, respectively, produced similar increases in sna between control and dexamethasone-treated rats. |
2015-10-19 |
2023-08-13 |
rat |
| Robert A Whittington, Alexis Bretteville, László Virág, Charles W Emala, Thomas O Maurin, François Marcouiller, Carl Julien, Franck R Petry, Noura B El-Khoury, Françoise Morin, Jean Charron, Emmanuel Plane. Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation. Scientific reports. vol 3. 2014-06-23. PMID:24045785. |
the purpose of this study was to explore the mechanism of anesthesia-mediated depression in arc gene and protein expression. |
2014-06-23 |
2023-08-12 |
mouse |
| Vikram Jakkamsetti, Nien-Pei Tsai, Christina Gross, Gemma Molinaro, Katie A Collins, Ferdinando Nicoletti, Kuan H Wang, Pavel Osten, Gary J Bassell, Jay R Gibson, Kimberly M Hube. Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for metabotropic glutamate receptor-dependent long-term synaptic depression. Neuron. vol 80. issue 1. 2013-12-23. PMID:24094104. |
however, in response to group 1 metabotropic glutamate receptor (mglur) activation, arcgfp+ neurons preferentially displayed long-term synaptic depression (mglur-ltd) and robust increases in dendritic arc protein. |
2013-12-23 |
2023-08-12 |
mouse |