| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tejaswi D Sudhakar, Swati Rane Levendovszky, Cyrus P Zabetian, Debby W Tsuang, Jagan A Pillai, Stephen M Rao, Odinachi Oguh, Carol Lippa, Oscar L Lopez, Sarah Berman, David J Irwin, Douglas R Galasko, Irene Litvan, Karen Marder, Lawrence S Honig, Jori E Fleisher, James E Galvin, Andrea Bozoki, Angela Taylor, Marwan Sabbagh, Dylan Wint, Brenna Cholerton, James B Leverenz, Valerie Olso. Developing Topics. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 19 Suppl 24. 2024-08-09. PMID:39120947. |
in this study, we identified hippocampal and amygdala subregions predictive of cognitive performance and motor symptoms severity measured by moca (montreal cognitive assessment) and mds-updrs iii, respectively, in patients with dementia with lewy bodies (dlb). |
2024-08-09 |
2024-08-12 |
Not clear |
| Osamu Yokota, Tomoko Miki, Hanae Nakashima-Yasuda, Hideki Ishizu, Takashi Haraguchi, Chikako Ikeda, Masato Hasegawa, Akinori Miyashita, Takeshi Ikeuchi, Naoto Nishikawa, Shintaro Takenoshita, Koichiro Sudo, Seishi Terada, Manabu Takak. Pure argyrophilic grain disease revisited: independent effects on limbic, neocortical, and striato-pallido-nigral degeneration and the development of dementia in a series with a low to moderate Braak stage. Acta neuropathologica communications. vol 12. issue 1. 2024-08-01. PMID:39085955. |
in multivariate analyses of 23 pagd and 28 control cases that lacked two or more lacunae and/or one or more large infarctions, 100 or more ags per × 400 visual field in the amygdala (or 10.02, 95% ci 1.12-89.43) and hippocampal ca1 (or 12.22, 95% ci 1.70-87.81), and the presence of ags in the inferior temporal cortex (or 8.18, 95% ci 1.03-65.13) affected dementia independent of age, moderate braak stages (iii-iv), and late-nc. |
2024-08-01 |
2024-08-03 |
Not clear |
| Sonal Agrawal, Lei Yu, Sue E Leurgans, Alifiya Kapasi, Lisa L Barnes, David A Bennett, Patricia A Boyle, Julie A Schneide. Grey matter ageing-related tau astrogliopathy: associations with brain pathologies and cognitive decline. Brain : a journal of neurology. 2024-07-24. PMID:39045644. |
in fully adjusted models that controlled for demographics, ad, and common age-related pathologies, an increase in severity of grey matter artag pathology in the superior frontal cortex, but not in the amygdala or the anterior temporal tip, was associated with higher odds of alzheimer's dementia and faster decline in global cognition, episodic memory, and semantic memory. |
2024-07-24 |
2024-07-26 |
human |
| Nolwazi Z Gcwensa, Dreson L Russell, Khaliah Y Long, Charlotte F Brzozowski, Xinran Liu, Karen L Gamble, Rita M Cowell, Laura A Volpicelli-Dale. Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala. Neurobiology of disease. 2024-07-07. PMID:38972360. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are characterized by neuronal α-synuclein (α-syn) inclusions termed lewy pathology, which are abundant in the amygdala. |
2024-07-07 |
2024-07-11 |
mouse |
| Nolwazi Z Gcwensa, Dreson L Russell, Khaliah Y Long, Charlotte F Brzozowski, Xinran Liu, Karen L Gamble, Rita M Cowell, Laura A Volpicelli-Dale. Cortico-amygdala synaptic structural abnormalities produced by templated aggregation of α-synuclein. bioRxiv : the preprint server for biology. 2024-05-27. PMID:38798467. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are characterized by neuronal α-synuclein (α-syn) inclusions termed lewy pathology, which are abundant in the amygdala. |
2024-05-27 |
2024-05-31 |
mouse |
| Jr-Jiun Liou, Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh, Nadim Farhat, Minjie Wu, Howard Aizenstein, Joseph M Mettenburg, William Yong, Elizabeth Head, Milos Ikonomovic, Tamer Ibrahim, Julia Kofle. Correlating hippocampal and amygdala volumes with neuropathological burden in neurodegenerative diseases using 7T postmortem MRI. medRxiv : the preprint server for health sciences. 2024-05-27. PMID:38798514. |
in ad, lower hippocampal volume associated with dementia duration, advanced thal phase, braak stage, late stage, and hs presence, whereas reduced amygdala volume correlated mainly with severe late stage and hs, but not with thal or braak stages. |
2024-05-27 |
2024-05-31 |
human |
| Jeremy L Thomas, Benjamin I Nilaver, Alejandro Lomniczi, Donald I Brown, Maria-Luisa Appleman, Steven G Kohama, Henryk F Urbansk. Pathological Markers of Alzheimer's Disease and Related Dementia in the Rhesus Macaque Amygdala. Journal of Alzheimer's disease reports. vol 8. issue 1. 2024-01-17. PMID:38229831. |
pathological markers of alzheimer's disease and related dementia in the rhesus macaque amygdala. |
2024-01-17 |
2024-01-19 |
human |
| Ulaş Ay, Zerrin Yıldırım, Emel Erdogdu, Ani Kiçik, Esin Ozturk-Isik, Tamer Demiralp, Hakan Gurvi. Shrinkage of olfactory amygdala connotes cognitive impairment in patients with Parkinson's disease. Cognitive neurodynamics. vol 17. issue 5. 2023-10-03. PMID:37786655. |
the volumes of nine nuclei of the amygdala were estimated with freesurfer (nuclear parcellation-np) from t1-weighted images of pd patients with normal cognition (pd-cn), pd with mild cognitive impairment (pd-mci), pd with dementia (pd-d), and hc. |
2023-10-03 |
2023-10-07 |
cat |
| Juhyun Son. Amygdala activity and amygdala-hippocampus connectivity: Metabolic diseases, dementia, and neuropsychiatric issues. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 162. 2023-04-03. PMID:37011482. |
thus, this review summarizes the significant consequences of the critical roles of amygdala connectivity in both metabolic syndromes and dementia. |
2023-04-03 |
2023-08-14 |
Not clear |
| Juhyun Son. Amygdala activity and amygdala-hippocampus connectivity: Metabolic diseases, dementia, and neuropsychiatric issues. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 162. 2023-04-03. PMID:37011482. |
further studies on amygdala function in metabolic imbalance-related dementia are needed to treat neuropsychiatric problems in patients with this type of dementia. |
2023-04-03 |
2023-08-14 |
Not clear |
| Kaitlin M Stouffer, Claire Chen, Sue Kulason, Eileen Xu, Menno P Witter, Can Ceritoglu, Marilyn S Albert, Susumu Mori, Juan Troncoso, Daniel J Tward, Michael I Mille. Early amygdala and ERC atrophy linked to 3D reconstruction of rostral neurofibrillary tau tangle pathology in Alzheimer's disease. NeuroImage. Clinical. vol 38. 2023-03-19. PMID:36934675. |
here, we use longitudinal diffeomorphometry to measure the atrophy rate from mri of the amygdala compared with that in the erc and tec in cognitively unimpaired (cu) controls, cu individuals who progressed to mild cognitive impairment (mci), and individuals with mci who progressed to dementia of the ad type (dat), using a dataset from the alzheimer's disease neuroimaging initiative (adni). |
2023-03-19 |
2023-08-14 |
Not clear |
| Juan Rivas, Santiago Gutierrez-Gomez, Juliana Villanueva-Congote, Jose Libreros, Joan Albert Camprodon, María Trujill. Subcortical Structures in Demented Schizophrenia Patients: A Comparative Study. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672741. |
structural differences were found in the hippocampus, amygdala, and thalamus; more evident in the amygdala and thalamus, which were mainly related to dementia. |
2023-01-21 |
2023-08-14 |
Not clear |
| Juan Rivas, Santiago Gutierrez-Gomez, Juliana Villanueva-Congote, Jose Libreros, Joan Albert Camprodon, María Trujill. Subcortical Structures in Demented Schizophrenia Patients: A Comparative Study. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672741. |
moreover, volume lost in the hippocampus, amygdala, and thalamus may be related to the possibility to develop dementia in schizophrenic patients. |
2023-01-21 |
2023-08-14 |
Not clear |
| Yebin Ahn, Keun Lee, Eun Bin Park, Sun Min Lee, So Young Moo. Transient Epileptic Amnesia With Amygdala Enlargement Presenting to a Dementia Clinic. Dementia and neurocognitive disorders. vol 21. issue 3. 2022-08-11. PMID:35949422. |
transient epileptic amnesia with amygdala enlargement presenting to a dementia clinic. |
2022-08-11 |
2023-08-14 |
Not clear |
| Jian Zhao, Wenqiang Li, Yue Wang, Yuanhe Jiang, Chunyan Ding, Huaibin Li, Jian Ding, Lin Wan. The effect of electroacupuncture on the expression of Sirt1 and STAT3 in hippocampus and amygdala of vascular dementia rats. Neuroreport. 2022-07-26. PMID:35882013. |
the effect of electroacupuncture on the expression of sirt1 and stat3 in hippocampus and amygdala of vascular dementia rats. |
2022-07-26 |
2023-08-14 |
rat |
| Grace M Lloyd, Zachary A Sorrentino, Stephan Quintin, Kimberly-Marie M Gorion, Brach M Bell, Giavanna Paterno, Brooke Long, Stefan Prokop, Benoit I Giasso. Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice. Acta neuropathologica. 2022-04-30. PMID:35488930. |
accumulation of αsyn inclusions is a key feature of dementia with lewy bodies (dlb) and multiple system atrophy (msa), and are found as additional pathology in alzheimer's disease (ad) such as ad with amygdala predominant lewy bodies (ad/alb). |
2022-04-30 |
2023-08-13 |
mouse |
| Matthew D Cykowski, Anithachristy S Arumanayagam, Suzanne Z Powell, Andreana L Rivera, Erin L Abner, Gustavo C Roman, Joseph C Masdeu, Peter T Nelso. Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies. Acta neuropathologica. 2022-04-02. PMID:35366087. |
the most common patterns were: pattern 1, with lamina ii tdp-43 + processes and preinclusion pathology in cortices of the amygdala region, and frequent late-nc stage 3 with hs; pattern 2, previously described as type-β, with neurofibrillary tangle-like tdp-43 neuronal cytoplasmic inclusions (ncis), high alzheimer's disease neuropathologic change (adnc), frequent apoe ε4, and usually late-nc stage 2; pattern 3, with round ncis and thick neurites in amygdala, younger age at death, and often comorbid lewy body disease; and pattern 4 (the most common pattern), with tortuous tdp-43 processes in subpial and wm regions, low adnc, rare hs, and lower dementia probability. |
2022-04-02 |
2023-08-13 |
human |
| Jozsef Gal, Yuriko Katsumata, Haining Zhu, Sukanya Srinivasan, Jing Chen, Lance Allen Johnson, Wang-Xia Wang, Lesley Renee Golden, Donna M Wilcock, Gregory A Jicha, Matthew D Cykowski, Peter Tobias Nelso. Apolipoprotein E proteinopathy is a major dementia-associated pathologic biomarker in individuals with or without the APOE epsilon 4 allele. The American journal of pathology. 2021-12-26. PMID:34954207. |
the amygdala is vulnerable to multiple or "mixed" mis-aggregated proteins associated with neurodegenerative conditions that can manifest clinically with amnestic dementia; the amygdala region is often affected even at earliest disease stages. |
2021-12-26 |
2023-08-13 |
human |
| Ethan W Hass, Zachary A Sorrentino, Yuxing Xia, Grace M Lloyd, John Q Trojanowski, Stefan Prokop, Benoit I Giasso. Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies. Acta neuropathologica communications. vol 9. issue 1. 2021-09-10. PMID:34454615. |
synucleinopathies, including parkinson's disease (pd), lewy body dementia (lbd), alzheimer's disease with amygdala restricted lewy bodies (ad/alb), and multiple system atrophy (msa) comprise a spectrum of neurodegenerative disorders characterized by the presence of distinct pathological α-synuclein (αsyn) inclusions. |
2021-09-10 |
2023-08-13 |
Not clear |
| Mario F Mende. Degenerative dementias: Alterations of emotions and mood disorders. Handbook of clinical neurology. vol 183. 2021-08-17. PMID:34389121. |
the neuropathology of these dementias extends to structures involved in emotional processing, including the basolateral limbic network (orbitofrontal cortex, anterior temporal lobe, amygdala, and thalamus), the insula, and ventromedial frontal lobe. |
2021-08-17 |
2023-08-13 |
Not clear |