| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sisi Yang, Ziliang Ye, Panpan He, Yuanyuan Zhang, Mengyi Liu, Chun Zhou, Yanjun Zhang, Xiaoqin Gan, Yu Huang, Hao Xiang, Xianhui Qi. Plasma proteomics for risk prediction of Alzheimer's disease in the general population. Aging cell. 2024-09-10. PMID:39252463. |
we aimed to develop and validate a protein risk score for predicting alzheimer's disease (ad) and compare its performance with a validated clinical risk model (cognitive health and dementia risk index for ad [cogdrisk-ad]) and apolipoprotein e (apoe) genotypes. |
2024-09-10 |
2024-09-13 |
human |
| Tamara Shiner, Gitit Kavé, Anat Mirelman, Keren Regev, Yoav Piura, Orly Goldstein, Mali Gana Weisz, Anat Bar-Shira, Tanya Gurevich, Avi Orr-Urtreger, Roy N Alcalay, Nir Giladi, Noa Bregma. Effect of GBA1 Mutations and APOE Polymorphisms on Survival and Progression Among Ashkenazi Jews with Dementia with Lewy Bodies. Movement disorders : official journal of the Movement Disorder Society. 2024-08-30. PMID:39212252. |
effect of gba1 mutations and apoe polymorphisms on survival and progression among ashkenazi jews with dementia with lewy bodies. |
2024-08-30 |
2024-09-04 |
Not clear |
| Miguel Baquero, Laura Ferré-González, Lourdes Álvarez-Sánchez, Inés Ferrer-Cairols, Lorena García-Vallés, Mar Peretó, Luis Raga, Gemma García-Lluch, Carmen Peña-Bautista, Beatriz Muria, Aitana Prieto, Inés Jareño, Consuelo Cháfer-Pericá. Insights from a 7-Year Dementia Cohort (VALCODIS): ApoE Genotype Evaluation. Journal of clinical medicine. vol 13. issue 16. 2024-08-29. PMID:39200877. |
insights from a 7-year dementia cohort (valcodis): apoe genotype evaluation. |
2024-08-29 |
2024-09-01 |
Not clear |
| Petrice M Cogswell, Trevor J Andrews, Jerome A Barakos, Frederik Barkhof, Suzie Bash, Marc Daniel Benayoun, Gloria C Chiang, Ana M Franceschi, Clifford R Jack, Jay J Pillai, Tina Young Poussaint, Cyrus A Raji, Vijay K Ramanan, Jody Tanabe, Lawrence Tanenbaum, Christopher T Whitlow, Fang F Yu, Greg Zaharchuk, Michael Zeinah, Tammie S Benzinge. Alzheimer's Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for ARIA Monitoring. AJNR. American journal of neuroradiology. 2024-08-23. PMID:39179297. |
based on consensus discussion within an expanded asnr alzheimer's, aria, and dementia study group, we will: (1) summarize the fda guidelines for evaluation of radiographic aria; (2) review the three key mri sequences for aria monitoring and standardized imaging protocols based on asnr-industry collaborations; (3) provide imaging recommendations for three key patient scenarios; (4) highlight the role of the radiologist in the care team for this population; (5) discuss implementation of mri protocols to detect aria in diverse practice settings; and (6) present results of the 2023 asnr international neuroradiologist practice survey on dementia and aria imaging.abbreviations: ad = alzheimer's disease; aria = amyloid-related imaging abnormalities; apoe = apolipoprotein-e; cms = centers for medicare & medicaid services; mci = mild cognitive impairment. |
2024-08-23 |
2024-08-27 |
Not clear |
| Rodrigo Canovas, Paul Maruff, Christopher J Fowler, Stephanie R Rainey-Smith, Colin L Masters, James D Doeck. Clinical Manifestations. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 19 Suppl 18. 2024-08-07. PMID:39112039. |
positive ad biomarkers, (e.g., amyloid, tau, or apoe ε4 carriage), increase rates of cognitive decline and transition to dementia. |
2024-08-07 |
2024-08-10 |
Not clear |
| Paul C R Hopkins, Claire Troakes, Andrew King, Guy Tea. Transmembrane and coiled-coil 2 associates with Alzheimer's disease pathology in the human brain. Brain pathology (Zurich, Switzerland). 2024-07-31. PMID:39084860. |
at the protein level, western blots of human brain extracts revealed that human brain-derived tmcc2 exists as at least three isoforms, the relative abundance of which varied between the temporal gyrus and cerebellum and was influenced by apoe and/or dementia status. |
2024-07-31 |
2024-08-03 |
human |
| Courtney M Kloske, Michael E Belloy, Elizabeth E Blue, Gregory R Bowman, Maria C Carrillo, Xiaoying Chen, Ornit Chiba-Falek, Albert A Davis, Gilbert Di Paolo, Francesca Garretti, David Gate, Lesley R Golden, Jay W Heinecke, Joachim Herz, Yadong Huang, Costantino Iadecola, Lance A Johnson, Takahisa Kanekiyo, Celeste M Karch, Anastasia Khvorova, Sascha J Koppes-den Hertog, Bruce T Lamb, Paige E Lawler, Yann Le Guen, Alexandra Litvinchuk, Chia-Chen Liu, Simin Mahinrad, Edoardo Marcora, Claudia Marino, Danny M Michaelson, Justin J Miller, Josh M Morganti, Priyanka S Narayan, Michel S Naslavsky, Marlies Oosthoek, Kapil V Ramachandran, Abhirami Ramakrishnan, Ana-Caroline Raulin, Aiko Robert, Rasha N M Saleh, Claire Sexton, Nilomi Shah, Francis Shue, Isabel J Sible, Andrea Soranno, Michael R Strickland, Julia Tcw, Manon Thierry, Li-Huei Tsai, Ryan A Tuckey, Jason D Ulrich, Rik van der Kant, Na Wang, Cheryl L Wellington, Stacie C Weninger, Hussein N Yassine, Na Zhao, Guojun Bu, Alison M Goate, David M Holtzma. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-07-20. PMID:39031528. |
advancements in apoe and dementia research: highlights from the 2023 aaic advancements: apoe conference. |
2024-07-20 |
2024-07-24 |
Not clear |
| Zhao Yao, Jie Wang, Tianfang Zhang, Hongjing Ai, Zeinab Abdelrahman, Xiaohong Wu, Daming Wang, Fenfen Chen, Ziwei Zhang, Xiaosheng Wang, Zuyun Liu, Zuobing Che. Age, sex, and APOE gene-specific associations between dynapenic obesity and dementia in a large cohort. The journal of nutrition, health & aging. vol 28. issue 8. 2024-07-10. PMID:38986174. |
age, sex, and apoe gene-specific associations between dynapenic obesity and dementia in a large cohort. |
2024-07-10 |
2024-07-13 |
Not clear |
| Carmine Zoccali, Giovambattista Capass. Genetic biomarkers of cognitive impairment and dementia of potential interest in CKD patients. Journal of nephrology. 2024-07-06. PMID:38970746. |
these markers include apolipoprotein e (apoe), complement receptor 1 (cr1), clusterin (clu), sortilin-related receptor 1 (sorl1), catechol-o-methyltransferase (comt), and brain-derived neurotrophic factor (bdnf), all of which are known to be associated with cognitive dysfunction and dementia in other populations. |
2024-07-06 |
2024-07-12 |
Not clear |
| Zoe E Neale, Jennifer R Fonda, Mark W Miller, Erika J Wolf, Rui Zhang, Richard Sherva, Kelly M Harrington, Victoria Merritt, Matthew S Panizzon, Richard L Hauger, J Michael Gaziano, Mark W Logu. Subjective cognitive concerns, APOE ε4, PTSD symptoms, and risk for dementia among older veterans. Alzheimer's research & therapy. vol 16. issue 1. 2024-07-02. PMID:38951900. |
subjective cognitive concerns, apoe ε4, ptsd symptoms, and risk for dementia among older veterans. |
2024-07-02 |
2024-07-04 |
Not clear |
| Ava Rashtchian, Mohammad Hossein Etemadi, Elham Asadi, Sara Binaei, Mina Abbasi, Maedeh Bayani, Erfan Izadi, Sayedeh-Fatemeh Sadat-Madani, Mahdyieh Naziri, Sahar Khoshravesh, Mahsa Shirani, Mahsa Asadi Anar, Niloofar Derav. Diabetes mellitus and risk of incident dementia in APOE ɛ4 carriers: an updated meta-analysis. BMC neuroscience. vol 25. issue 1. 2024-06-25. PMID:38918708. |
diabetes mellitus and risk of incident dementia in apoe ɛ4 carriers: an updated meta-analysis. |
2024-06-25 |
2024-06-29 |
Not clear |
| Ava Rashtchian, Mohammad Hossein Etemadi, Elham Asadi, Sara Binaei, Mina Abbasi, Maedeh Bayani, Erfan Izadi, Sayedeh-Fatemeh Sadat-Madani, Mahdyieh Naziri, Sahar Khoshravesh, Mahsa Shirani, Mahsa Asadi Anar, Niloofar Derav. Diabetes mellitus and risk of incident dementia in APOE ɛ4 carriers: an updated meta-analysis. BMC neuroscience. vol 25. issue 1. 2024-06-25. PMID:38918708. |
in this study, we aim to evaluate diabetes mellitus and the risk of incident dementia in apoe ɛ4 carriers. |
2024-06-25 |
2024-06-29 |
Not clear |
| Pedro Montejo Carrasco, Mercedes Montenegro-Peña, David Prada Crespo, Inmaculada Rodríguez Rojo, Ana Barabash Bustelo, Borja Montejo Rubio, Alberto Marcos Dolado, Fernando Maestú Unturbe, María Luisa Delgado Losad. APOE genotype, hippocampal volume, and cognitive reserve predict improvement by cognitive training in older adults without dementia: a randomized controlled trial. Cognitive processing. 2024-06-19. PMID:38896211. |
apoe genotype, hippocampal volume, and cognitive reserve predict improvement by cognitive training in older adults without dementia: a randomized controlled trial. |
2024-06-19 |
2024-06-21 |
human |
| Yi Zhe Wang, Wei Zhao, Priya Moorjani, Alden L Gross, Xiang Zhou, Aparajit B Dey, Jinkook Lee, Jennifer A Smith, Sharon L R Kardi. Effect of apolipoprotein E ε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI-DAD. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-06-18. PMID:38889280. |
we investigated the effects of apolipoprotein e (apoe) ε4 and its interactions with sociodemographic characteristics on cognitive measures in south asians from the diagnostic assessment of dementia for the longitudinal aging study of india (lasi-dad). |
2024-06-18 |
2024-06-21 |
Not clear |
| Jr-Jiun Liou, Jerry Lou, Jamie Nakagiri, William Yong, Christy L Hom, Eric W Doran, Minodora Totoiu, Ira Lott, Mark Mapstone, David B Keator, Adam M Brickman, Sierra Wright, Brittany Nelson, Florence Lai, Laura Xicota, Lam-Ha T Dang, Jinghang Li, Tales Santini, Joseph M Mettenburg, Milos D Ikonomovic, Julia Kofler, Tamer Ibrahim, Elizabeth Hea. A Neuropathology Case Report of a Woman with Down Syndrome who Remained Cognitively Stable. medRxiv : the preprint server for health sciences. 2024-06-17. PMID:38883742. |
notably, her apoe genotype was e2/3, which is associated with a decreased risk of dementia. |
2024-06-17 |
2024-06-19 |
human |
| Meiling Li, Ruihong Yu, Xiaoyi Wang, Yanqing Zhao, Qixiang Song, Qi Wang, Chunying Fu, Shiva Raj Mishra, Nipun Shrestha, Salim S Virani, Dongshan Zh. Association between ABO genotypes and risk of dementia and neuroimaging markers: roles of sex and APOE status. Frontiers in neurology. vol 15. 2024-06-12. PMID:38863509. |
association between abo genotypes and risk of dementia and neuroimaging markers: roles of sex and apoe status. |
2024-06-12 |
2024-06-14 |
Not clear |
| Meiling Li, Ruihong Yu, Xiaoyi Wang, Yanqing Zhao, Qixiang Song, Qi Wang, Chunying Fu, Shiva Raj Mishra, Nipun Shrestha, Salim S Virani, Dongshan Zh. Association between ABO genotypes and risk of dementia and neuroimaging markers: roles of sex and APOE status. Frontiers in neurology. vol 15. 2024-06-12. PMID:38863509. |
whether the relationships between abo blood genotypes (aa, ao, bb, bo, ab, and oo) and dementia are modified by gender and apoe status has been unclear. |
2024-06-12 |
2024-06-14 |
Not clear |
| Renhao Luo, Dena Zeraatkar, Maria Glymour, Randall J Ellis, Hossein Estiri, Chirag J Pate. Specification curve analysis to identify heterogeneity in risk factors for dementia: findings from the UK Biobank. BMC medicine. vol 22. issue 1. 2024-05-29. PMID:38807092. |
in 2020, the lancet commission identified 12 risk factors as priorities for prevention of dementia, and other studies identified apoe e4/e4 genotype and family history of alzheimer's disease strongly associated with dementia outcomes; however, it is unclear how robust these relationships are across dementia subtypes and analytic scenarios. |
2024-05-29 |
2024-06-02 |
Not clear |
| M Singh, V Majumda. Design and Rationale of a Two-Armed Randomized Controlled Trial on Yoga/Brisk Walking-Based Lifestyle Modification on Dementia Risk Reduction, and Influence of ApoE Genotypes on the Intervention. JAR life. vol 13. 2024-05-21. PMID:38764503. |
design and rationale of a two-armed randomized controlled trial on yoga/brisk walking-based lifestyle modification on dementia risk reduction, and influence of apoe genotypes on the intervention. |
2024-05-21 |
2024-05-27 |
human |
| Kate E Foley, Donna M Wilcoc. Three major effects of APOE Frontiers in aging neuroscience. vol 16. 2024-05-18. PMID:38756535. |
three major effects of apoe the targeting of amyloid-beta (aβ) plaques therapeutically as one of the primary causes of alzheimer's disease (ad) dementia has been an ongoing effort spanning decades. |
2024-05-18 |
2024-05-27 |
Not clear |