| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dong Yeol Kim, Sang-Min Kim, Inn-Oc Ha. Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer's disease by decreasing brain O-GlcNAc cycling in mice. Journal of neuroinflammation. vol 21. issue 1. 2024-07-24. PMID:39044290. |
notably, overexpressing o-glcnac transferase in the dentate gyrus region of the mouse brain rescued csd-induced cognitive dysfunction, neuropathy, neuroinflammation, and er stress responses. |
2024-07-24 |
2024-07-26 |
mouse |
| Eliedonna Cacao, Sidath Kapukotuwa, Francis A Cucinott. Modeling Reveals the Dependence of Hippocampal Neurogenesis Radiosensitivity on Age and Strain of Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30618596. |
cognitive dysfunction following radiation treatment for brain cancers in both children and adults have been correlated to impairment of neurogenesis in the hippocampal dentate gyrus. |
2020-10-01 |
2023-08-13 |
mouse |
| Julia B Kahn, Russell G Port, Cuiyong Yue, Hajime Takano, Douglas A Coulte. Circuit-based interventions in the dentate gyrus rescue epilepsy-associated cognitive dysfunction. Brain : a journal of neurology. vol 142. issue 9. 2020-05-12. PMID:31363737. |
circuit-based interventions in the dentate gyrus rescue epilepsy-associated cognitive dysfunction. |
2020-05-12 |
2023-08-13 |
mouse |
| Pei-Jun Li, Ying-Qiang Guo, Pei-Yan Ding, Ruo-Bing Liu, Fei Deng, Xiao-Xue Feng, Wen-Jun Ya. Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats. Neurological research. vol 41. issue 10. 2020-03-23. PMID:31221056. |
neuroprotective effects of a smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats. |
2020-03-23 |
2023-08-13 |
rat |
| Diana M Sama, Shaun W Carlson, Binoy Joseph, Stefanie Saenger, Friedrich Metzger, Kathryn E Saatma. Assessment of systemic administration of PEGylated IGF-1 in a mouse model of traumatic brain injury. Restorative neurology and neuroscience. vol 36. issue 4. 2018-10-15. PMID:29889090. |
traumatic brain injury can result in lasting cognitive dysfunction due to degeneration of mature hippocampal neurons as well as the loss of immature neurons within the dentate gyrus. |
2018-10-15 |
2023-08-13 |
mouse |
| Li Tian, Huang Nie, Yang Zhang, Yu Chen, Zhengwu Peng, Min Cai, Haidong Wei, Pei Qin, Hailong Dong, Lize Xion. Recombinant human thioredoxin-1 promotes neurogenesis and facilitates cognitive recovery following cerebral ischemia in mice. Neuropharmacology. vol 77. 2014-08-26. PMID:24212059. |
in adult mammals, the hippocampal dentate gyrus contains neural stem cells (nscs) that continuously generate newborn neurons and integrate into the pre-existing networks throughout life, which may ameliorate cognitive dysfunction following ci. |
2014-08-26 |
2023-08-12 |
mouse |
| N Realini, D Vigano', C Guidali, E Zamberletti, T Rubino, D Parolar. Chronic URB597 treatment at adulthood reverted most depressive-like symptoms induced by adolescent exposure to THC in female rats. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20850463. |
since it has been reported that deficits in adult hippocampal neurogenesis may underlie the cognitive dysfunction seen in depression, we then survey cell proliferation in the dentate gyrus of the hippocampus. |
2011-11-22 |
2023-08-12 |
rat |
| Robert F Hunt, Stephen W Scheff, Bret N Smit. Synaptic reorganization of inhibitory hilar interneuron circuitry after traumatic brain injury in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 18. 2011-08-05. PMID:21543618. |
functional plasticity of synaptic networks in the dentate gyrus has been implicated in the development of posttraumatic epilepsy and in cognitive dysfunction after traumatic brain injury, but little is known about potentially pathogenic changes in inhibitory circuits. |
2011-08-05 |
2023-08-12 |
mouse |
| Nishi Srivastava, Kavita Seth, Nalini Srivastava, Vinay K Khanna, Ashok Kumar Agrawa. Functional restoration using basic fibroblast growth factor (bFGF) infusion in Kainic acid induced cognitive dysfunction in rat: neurobehavioural and neurochemical studies. Neurochemical research. vol 33. issue 7. 2008-08-20. PMID:17955369. |
the results suggest restorative potential of bfgf in cognitive dysfunctions, possibly due to mitogenic effect on dentate gyrus neurogenic area leading to generation and migration of newer cholinergic neurons. |
2008-08-20 |
2023-08-12 |
rat |
| Charles L Limoli, Radoslaw Rola, Erich Giedzinski, Sailaja Mantha, Ting-Ting Huang, John R Fik. Cell-density-dependent regulation of neural precursor cell function. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 45. 2004-12-28. PMID:15522966. |
stress-induced reductions of neural precursor cells from the subgranular zone of the hippocampal dentate gyrus have been linked to impaired neurogenesis and cognitive dysfunction. |
2004-12-28 |
2023-08-12 |
mouse |
| Katsuji Nishi, Akio Tanegashima, Yoshio Yamamoto, Ikuko Ushiyama, Keiko Ikemoto, Shigeru Yamasaki, Akiyoshi Nishimura, Steven Rand, Bernd Brinkman. Utilization of lectin-histochemistry in forensic neuropathology: lectin staining provides useful information for postmortem diagnosis in forensic neuropathology. Legal medicine (Tokyo, Japan). vol 5. issue 3. 2004-05-14. PMID:14568771. |
the spherical deposits were newly detected by lectin staining in the molecular layer of the dentate gyrus of the hippocampal formation chiefly from patients with schizophrenia or cognitive dysfunctions. |
2004-05-14 |
2023-08-12 |
human |
| M E Gilbert, C M Mack, S M Lasle. Chronic developmental lead exposure and hippocampal long-term potentiation: biphasic dose-response relationship. Neurotoxicology. vol 20. issue 1. 1999-05-19. PMID:10091860. |
we have used long-term potentiation (ltp) in the dentate gyrus of the pb-exposed rats to determine the potential of a reduced capacity for synaptic plasticity to contribute to pb-induced cognitive dysfunction. |
1999-05-19 |
2023-08-12 |
rat |