| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shanshan Wang, Zankai Wu, Xueshan Bu, Xuan Peng, Qin Zhou, Wenqin Song, Wenwei Gao, Wei Wang, Zhongyuan Xi. MEF2C Alleviates Postoperative Cognitive Dysfunction by Repressing Ferroptosis. CNS neuroscience & therapeutics. vol 30. issue 10. 2024-10-01. PMID:39350345. |
ferroptosis, a form of programmed cell death featured by lipid peroxidation, has been proposed as a potential etiology for postoperative cognitive dysfunction (pocd). |
2024-10-01 |
2024-10-03 |
Not clear |
| Yang Li, Xianghan Ruan, Miao Sun, Mengyao Yuan, Jie Song, Zhikang Zhou, Hao Li, Yulong Ma, Weidong Mi, Xiaoying Zhan. Iron deposition participates in LPS-induced cognitive impairment by promoting neuroinflammation and ferroptosis in mice. Experimental neurology. 2024-06-12. PMID:38866103. |
taken together, our findings suggested that dfo exerts neuroprotective effects by alleviating excessive iron participation in lipid peroxidation, reducing the occurrence of ferroptosis, inhibiting the vicious cycle between oxidative stress and inflammation, and ultimately ameliorating lps-induced cognitive dysfunction, providing novel insights into the immunopathogenesis of inflammation-related cognitive dysfunction and future potential prevention options targeting iron. |
2024-06-12 |
2024-06-15 |
mouse |
| Mahesh Rachamalla, Arash Salahinejad, Maria Khan, Ashok Kumar Datusalia, Som Niyog. Chronic dietary exposure to arsenic at environmentally relevant concentrations impairs cognitive performance in adult zebrafish (Danio rerio) via oxidative stress and dopaminergic dysfunction. The Science of the total environment. 2023-05-10. PMID:37164085. |
concomitant with cognitive dysfunction, chronic dietary exposure to arsenic was also found to increase arsenic accumulation and dopamine levels, and induce oxidative stress (reduced thiol redox, increased lipid peroxidation and expression of antioxidant enzyme genes) in the brain of zebrafish in a dose-dependent manner. |
2023-05-10 |
2023-08-14 |
zebrafish |
| A H Alhowail, Y S Almogbel, A A H Abdellatif, M A Aldubayan, I S Almam. Elucidating the mechanism underlying cognitive dysfunction by investigating the effects of CMF and MET treatment on hippocampal neurons. European review for medical and pharmacological sciences. vol 26. issue 3. 2022-02-18. PMID:35179739. |
to elucidate the potential mechanism underlying cognitive dysfunction, we investigated the impact of cmf and met treatment on the activities of mitochondrial respiratory chain complexes i and iv, as well as lipid peroxidation, in hippocampal neurons. |
2022-02-18 |
2023-08-13 |
Not clear |
| Praveen K Kodumuri, Christofer Thomas, Raghu Jetti, Anil Kumar Pande. Fenugreek seed extract ameliorates cognitive deficits in streptozotocin-induced diabetic rats. Journal of basic and clinical physiology and pharmacology. vol 30. issue 4. 2020-01-06. PMID:31326961. |
conclusion in conclusion, administration of t. foenum-graecum seed extract ameliorates diabetes-linked cognitive dysfunction in rats by decreasing blood glucose levels, reducing lipid peroxidation and oxidative stress in the hippocampus, and preventing neuronal loss from the hippocampus. |
2020-01-06 |
2023-08-13 |
rat |
| Anil Kumar, Atish Prakash, Samrita Dogr. Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats. Pharmacological reports : PR. vol 63. issue 4. 2012-02-10. PMID:22001979. |
aluminium chloride (100 mg/kg) was administered daily for six weeks that significantly increased cognitive dysfunction in the morris water maze and oxidative damage as indicated by a rise in lipid peroxidation and nitrite concentration and depleted reduced glutathione, superoxide dismutase, catalase and glutathione s-transferase activity compared to sham treatment. |
2012-02-10 |
2023-08-12 |
rat |
| Meghan M Murphy, Elizabeth D Miller, Eugene E Fibuch, Norbert W Seidle. Redox mechanism of neurotoxicity by a serotonin-acrolein polymeric melanoid. Neurotoxicity research. vol 19. issue 2. 2011-11-09. PMID:20309663. |
postoperative cognitive dysfunction may be associated with the toxic products of lipid peroxidation, such as the α,β-unsaturated aldehyde acrolein, which accumulates in aging. |
2011-11-09 |
2023-08-12 |
Not clear |
| Elizabeth D Miller, Eugene E Fibuch, Norbert W Seidle. Toxicity of a serotonin-derived neuromelanin. Biochemical and biophysical research communications. vol 391. issue 2. 2010-03-08. PMID:20026057. |
postoperative cognitive dysfunction (pocd) is associated with increased mortality in the elderly and may occur from lipid peroxidation in aging. |
2010-03-08 |
2023-08-12 |
Not clear |
| Michio Hashimoto, Yoko Kubota, Naoko Tanaka, Yu Yamaguchi, Yoshimi Fujii, Satomi Kagota, Eisuke Kawakita, Osamu Shido, Masaru Kunitomo, Kazumasa Shinozuk. Relationship between plasma and hippocampal lipid peroxidation in obese and hypertensive SHR/NDmcr-cp rats. Clinical and experimental pharmacology & physiology. vol 31 Suppl 2. 2008-02-27. PMID:15649293. |
to understand cognitive dysfunction in metabolic syndrome, the relationship between the plasma and the hippocampus regarding fatty acid composition and lipid peroxidation was estimated in genetically hypertensive and obese shr/ndmcr-cp rats (shr-cp) aged 7-9 and 18-20 weeks. |
2008-02-27 |
2023-08-12 |
rat |