Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Maxwell Eisenbaum, Andrew Pearson, Camila Ortiz, Michael Mullan, Fiona Crawford, Joseph Ojo, Corbin Bachmeie. ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytes. Glia. 2023-09-05. PMID:37668005. |
furthermore, exposure to repetitive mild traumatic brain injuries exacerbated the apoe4-induced impairments in tau processing and elimination by astrocytes in apoe4 targeted-replacement mice. |
2023-09-05 |
2023-09-07 |
mouse |
Alyssa F Pybus, Sara Bitarafan, Rowan O Brothers, Alivia Rohrer, Arushi Khaitan, Felix Rivera Moctezuma, Kareena Udeshi, Brae Davies, Sydney Triplett, Eric Dammer, Srikant Rangaraju, Erin M Buckley, Levi B Woo. Profiling the neuroimmune cascade in 3xTg mice exposed to successive mild traumatic brain injuries. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37397993. |
repetitive mild traumatic brain injuries (rmtbi) sustained within a window of vulnerability can result in long term cognitive deficits, depression, and eventual neurodegeneration associated with tau pathology, amyloid beta (a\xce\xb2) plaques, gliosis, and neuronal and functional loss. |
2023-07-03 |
2023-08-14 |
mouse |
Iftakher Hossain, Kaj Blennow, Jussi P Posti, Henrik Zetterber. Tau as a fluid biomarker of concussion and neurodegeneration. Concussion (London, England). vol 7. issue 2. 2023-01-23. PMID:36687115. |
tau has been extensively studied in recent years, particularly in repetitive mild traumatic brain injuries and sports-related concussions. |
2023-01-23 |
2023-08-14 |
Not clear |
Ekta J Shah, Katherine Gurdziel, Douglas M Rude. Sex-Differences in Traumatic Brain Injury in the Absence of Tau in Genes. vol 12. issue 6. 2021-09-07. PMID:34198629. |
sex-differences in traumatic brain injury in the absence of tau in traumatic brain injuries, a leading cause of death and disability worldwide, are caused by a severe impact to the head that impairs physiological and psychological function. |
2021-09-07 |
2023-08-13 |
Not clear |
Yuto Uchida, Yoshihiko Horimoto, Haruto Shibata, Tomoyuki Kuno, Toshihiko Usami, Koji Takada, Akihiko Iida, Yoshino Ueki, Nobuyuki Okamura, Noriyuki Matsukaw. Occipital Tau Deposition and Astrogliosis After Traumatic Brain Injuries in a Kendo Player. Neurology. Clinical practice. vol 11. issue 4. 2021-09-07. PMID:34484965. |
occipital tau deposition and astrogliosis after traumatic brain injuries in a kendo player. |
2021-09-07 |
2023-08-13 |
Not clear |
Nicholas J Braun, Katherine R Yao, Patrick W Alford, Dezhi Lia. Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 46. 2021-01-25. PMID:33139536. |
chronic traumatic encephalopathy (cte) is associated with repeated traumatic brain injuries (tbi) and is characterized by cognitive decline and the presence of neurofibrillary tangles (nfts) of the protein tau in patients' brains. |
2021-01-25 |
2023-08-13 |
rat |
Alice Bittar, Nemil Bhatt, Tasneem F Hasan, Mauro Montalbano, Nicha Puangmalai, Salome McAllen, Anna Ellsworth, Mariana Carretero Murillo, Giulio Taglialatela, Brandon Lucke-Wold, Aric Logsdon, Charles Rosen, Ryan C Turner, Rakez Kaye. Neurotoxic tau oligomers after single versus repetitive mild traumatic brain injury. Brain communications. vol 1. issue 1. 2020-09-28. PMID:31608324. |
we demonstrated that single versus repetitive mild traumatic brain injuries frequencies lead to the formation of different tau oligomeric polymorphisms. |
2020-09-28 |
2023-08-13 |
mouse |
Alice Bittar, Nemil Bhatt, Tasneem F Hasan, Mauro Montalbano, Nicha Puangmalai, Salome McAllen, Anna Ellsworth, Mariana Carretero Murillo, Giulio Taglialatela, Brandon Lucke-Wold, Aric Logsdon, Charles Rosen, Ryan C Turner, Rakez Kaye. Neurotoxic tau oligomers after single versus repetitive mild traumatic brain injury. Brain communications. vol 1. issue 1. 2020-09-28. PMID:31608324. |
to our knowledge, this is the first evidence that soluble tau oligomers derived from single versus repetitive mild traumatic brain injuries form distinct polymorphisms that possibly correlate with the risk of neurodegeneration after mild traumatic brain injury. |
2020-09-28 |
2023-08-13 |
mouse |
Xin L Tan, David K Wright, Shijie Liu, Christopher Hovens, Terence J O'Brien, Sandy R Shult. Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes. Neuropharmacology. vol 108. 2017-07-18. PMID:27163189. |
repeated mild traumatic brain injuries increased the phosphorylation of tau and decreased pp2a/pr55, whilst inducing brain atrophy and cognitive and sensorimotor deficits. |
2017-07-18 |
2023-08-13 |
rat |
Xin L Tan, David K Wright, Shijie Liu, Christopher Hovens, Terence J O'Brien, Sandy R Shult. Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes. Neuropharmacology. vol 108. 2017-07-18. PMID:27163189. |
sodium selenate treatment increased pp2a/pr55, and decreased tau phosphorylation, brain damage, and cognitive and motor impairments in rats given repeated mild traumatic brain injuries. |
2017-07-18 |
2023-08-13 |
rat |
Anlys Olivera, Natasha Lejbman, Andreas Jeromin, Louis M French, Hyung-Suk Kim, Ann Cashion, Vincent Mysliwiec, Ramon Diaz-Arrastia, Jessica Gil. Peripheral Total Tau in Military Personnel Who Sustain Traumatic Brain Injuries During Deployment. JAMA neurology. vol 72. issue 10. 2016-01-30. PMID:26237304. |
peripheral total tau in military personnel who sustain traumatic brain injuries during deployment. |
2016-01-30 |
2023-08-13 |
Not clear |