Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yamei Zhang, Junying Liu, Xinyu Liu, Yan Zhou, Jia Geng, Zheng Shi, Li M. Fecal Microbiota Transplantation-Mediated Ghrelin Restoration Improves Neurological Functions After Traumatic Brain Injury: Evidence from 16S rRNA Sequencing and In Vivo Studies. Molecular neurobiology. 2023-09-05. PMID:37668964. |
further, in vivo experiments showed that fecal microbiota transplantation or ghrelin injection could block the intracerebral tnf signaling pathway, enhance glp-1 expression, significantly reduce brain edema post-tbi, promote the repair of the blood-brain barrier, and improve neurological deficits. |
2023-09-05 |
2023-09-07 |
rat |
Orhan Altay, Hidenori Suzuki, Yu Hasegawa, Robert P Ostrowski, Jiping Tang, John H Zhan. Isoflurane on brain inflammation. Neurobiology of disease. vol 62. 2014-09-03. PMID:24084689. |
in addition to the evaluation of brain injury (neurological scores, brain edema and evans blue dye extravasation), brain inflammation was evaluated by means of expression changes in markers of inflammatory cells (ionized calcium binding adaptor molecule-1, myeloperoxidase), cytokines (tumor necrosis factor [tnf]-\xce\xb1, interleukin-1\xce\xb2), adhesion molecules (intercellular adhesion molecule [icam]-1, p-selectin), inducers of inflammation (cyclooxygenase-2, phosphorylated c-jun n-terminal kinase [p-jnk]) and endothelial cell activation (von willebrand factor) at 24h post-sah. |
2014-09-03 |
2023-08-12 |
mouse |
Chantal B\\xc3\\xa9meur, Hong Qu, Paul Desjardins, Roger F Butterwort. IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure. Neurochemistry international. vol 56. issue 2. 2010-07-08. PMID:19931338. |
il-1 or tnf receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure. |
2010-07-08 |
2023-08-12 |
mouse |
Werner Stenzel, Sabine Soltek, Hrvoje Miletic, Manuel Marcel Hermann, Heinrich K\\xc3\\xb6rner, Jonathon D Sedgwick, Dirk Schl\\xc3\\xbcter, Martina Decker. An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance. Journal of neuropathology and experimental neurology. vol 64. issue 1. 2005-03-03. PMID:15715082. |
similarly, numbers of inflammatory leukocytes, cytokine expression of il-6, il-12p40, ifngamma il-beta mrna, and brain edema were significantly increased in tnf(0/0)mice as compared to wt animals. |
2005-03-03 |
2023-08-12 |
mouse |
G Farkas, J M\\xc3\\xa1rton, Z Nagy, Y M\\xc3\\xa1ndi, T Tak\\xc3\\xa1cs, M A Deli, C S Abrah\\xc3\\xa1. Experimental acute pancreatitis results in increased blood-brain barrier permeability in the rat: a potential role for tumor necrosis factor and interleukin 6. Neuroscience letters. vol 242. issue 3. 1998-05-14. PMID:9530927. |
we conclude that cytokines, such as tnf and il-6, may contribute to the vasogenic brain edema formation during acute pancreatitis. |
1998-05-14 |
2023-08-12 |
rat |
T Kita, L Liu, N Tanaka, Y Kinoshit. The expression of tumor necrosis factor-alpha in the rat brain after fluid percussive injury. International journal of legal medicine. vol 110. issue 6. 1998-01-22. PMID:9387012. |
the present study suggests that tnf alpha conveyed from the microglial cells is one co-factor contributing to the fluid percussive brain edema formation after moderate brain injury. |
1998-01-22 |
2023-08-12 |
rat |
Iu V Persidski\\xc4\\xad, Iu A Barshte\\xc4\\xadn, Iu I Kudriavet. [Cytological features of the development of multi-organ failure induced by exposure of the body to tumor necrosis factor]. TSitologiia i genetika. vol 26. issue 1. 1992-08-03. PMID:1621287. |
injection of 20 micrograms per mice of tumor necrosis factor (tnf) revealed the development of signs of multiorgan failure (interstitial and intraalveolar edema in the lung, acute fatty liver, tubular necrosis in kidney, brain edema) during first 24 h. the microvascular endothelial cells played a particular role in the state development. |
1992-08-03 |
2023-08-11 |
mouse |