| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xue Zhang, Hongling Liu, Chao Wan, Yijian Li, Chunge Ren, Jia Lu, Yong Liu, Yuli Yan. Verteporfin combined with ROCK inhibitor promotes the restoration of corneal endothelial cell dysfunction in rats. Biochemical pharmacology. 2024-11-21. PMID:39571917. |
corneal endothelial cells (cecs) dysfunction frequently results in a hazy, edematous cornea due to corneal endothelial decompensation and is a major cause of corneal blindness. |
2024-11-21 |
2024-11-24 |
human |
| Nina Kobal, Miha Marzidovšek, Petra Schollmayer, Elvira Maličev, Marko Hawlina, Zala Lužnik Marzidovše. Molecular and Cellular Mechanisms of the Therapeutic Effect of Mesenchymal Stem Cells and Extracellular Vesicles in Corneal Regeneration. International journal of molecular sciences. vol 25. issue 20. 2024-10-26. PMID:39456906. |
damage to the cornea resulting from trauma, infection, or disease can lead to blindness. |
2024-10-26 |
2024-10-29 |
human |
| Arpon Biswas, Abhijit Deb Choudhury, Anjali Mishra, Sarvesh Kumar Verma, Amol Chhatrapati Bisen, Sachin Nashik Sanap, Sristi Agrawal, Mukesh Kumar, Shivansh Kumar, Rabi Sankar Bhatt. Pharmacokinetic Analysis of Gatifloxacin and Dexamethasone in Rabbit Ocular Biofluid Using a Sensitive and Selective LC-MS/MS Method. Journal of mass spectrometry : JMS. vol 59. issue 10. 2024-10-01. PMID:39351617. |
bacterial keratitis (bk) is an infection that causes inflammation of the cornea and, if severe, can result in blindness. |
2024-10-01 |
2024-10-03 |
rabbit |
| Rachelle N Palchesko, Yiqin Du, Moira L Geary, Santiago Carrasquilla, Daniel J Shiwarski, Irona Khandaker, James L Funderburgh, Adam W Feinber. In vivo engraftment into the cornea endothelium using extracellular matrix shrink-wrapped cells. Communications materials. vol 3. issue 1. 2024-08-23. PMID:39175945. |
these results show that shrink-wrapping cells in extracellular matrix dramatically improves engraftment and provides a potential alternative to cornea transplant when low endothelial cell density is the cause of corneal blindness. |
2024-08-23 |
2024-08-25 |
Not clear |
| Xinhe Fang, Meijiao Ma, Weining Rong, Yuan-Yuan Lian, Xueli Wu, Yongying Gao, Hui-Ping Li, Xunlun Shen. Exome sequencing confirms the clinical diagnosis of both joubert syndrome and klinefelter syndrome with keratoconus in a han Chinese family. Frontiers in genetics. vol 15. 2024-07-31. PMID:39076169. |
keratoconus (kc) is a kind of genetically predisposed eye disease that causes blindness characterized by a dilated thinning of the central or paracentral cornea conically projected forward, highly irregular astigmatism, and severe visual impairment. |
2024-07-31 |
2024-08-02 |
Not clear |
| Rohan Bir Singh, Thomas H Dohlman, Alexander Ivanov, Nathan Hall, Connor Ross, Tobias Elze, Joan W Miller, Alice Lorch, Erdem Yuksel, Jia Yin, Reza Dan. Corneal Opacity in the United States: An American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) Study. Ophthalmology. 2024-07-10. PMID:38986874. |
vision loss associated with opacification of the cornea is one of the leading causes of blindness globally. |
2024-07-10 |
2024-07-13 |
Not clear |
| Merve Sen, Özgür Eroğu. Retinoic Acid Neutralizes the Effects of Herpes Simplex Virus Type 1-Infected Cell Protein 0 (ICP0) in Retinal Pigment Epithelial Cells. Cureus. vol 16. issue 5. 2024-06-26. PMID:38919217. |
herpes simplex virus (hsv) infection of the cornea, uvea, and retina is the leading infectious cause of blindness worldwide. |
2024-06-26 |
2024-06-29 |
Not clear |
| Jose Ferreira da Cunha Neto, Walicyranison Plinio da Silva Rocha, Georgios Makris, Marcelo Sandoval-Denis, Ferry Hagen, Pedro Willem Crous, Guilherme Maranhão Chave. Fusarioid keratitis and other superficial infections: A 10-years prospective study from Northeastern Brazil. PLoS neglected tropical diseases. vol 18. issue 6. 2024-06-17. PMID:38885283. |
fusarioid keratitis is characterized by an infection of the cornea with a suppurative and ulcerative appearance, which may cause damage to vision and permanent blindness. |
2024-06-17 |
2024-06-21 |
Not clear |
| Zhengwei Ge, Linyu Long, Fanjun Zhang, Ruiqi Dong, Zhongping Chen, Shibo Tang, Li Yang, Yunbing Wan. Development of an injectable oxidized dextran/gelatin hydrogel capable of promoting the healing of alkali burn-associated corneal wounds. International journal of biological macromolecules. 2024-06-02. PMID:38825267. |
the cornea serves as an essential shield that protects the underlying eye from external conditions, yet it remains highly vulnerable to injuries that could lead to blindness and scarring if not promptly and effectively treated. |
2024-06-02 |
2024-06-05 |
rat |
| Kuang-Yi Shih, Yao-Tsung Chang, Yu-Jen Wang, Jian-Ming Huan. Ouabain, ATPase inhibitor, potentially enhances the effect of polyhexamethylene biguanide on Acanthamoeba castellanii. International journal for parasitology. Drugs and drug resistance. vol 25. 2024-05-31. PMID:38821038. |
ak, the most recognized disease, can cause permanent visual impairment or blindness by affecting the cornea. |
2024-05-31 |
2024-06-02 |
Not clear |
| S Krishna Chaitanya, Atriya Ghosh, Pranabendu Ganguly, Bhaskar Ray Chaudhuri, Santanu Dhar. A New Approach of Aspheric Intralamellar Keratoprostheses Optic Design made with poly(2-hydroxy ethylmethacrylate) Hydrogel. Biomedical physics & engineering express. 2024-05-07. PMID:38714186. |
keratoprosthesis (kpro) is a surgical procedure largely confined to end-stage corneal blindness correction, where artificial cornea substitutes the native tissue. |
2024-05-07 |
2024-05-27 |
Not clear |
| Pietro Bonato, Andrea Bagn. Replace or Regenerate? Diverse Approaches to Biomaterials for Treating Corneal Lesions. Biomimetics (Basel, Switzerland). vol 9. issue 4. 2024-04-26. PMID:38667213. |
the inner structures of the eye are protected by the cornea, which is a transparent membrane exposed to the external environment and subjected to the risk of lesions and diseases, sometimes resulting in impaired vision and blindness. |
2024-04-26 |
2024-04-28 |
human |
| Laura Trujillo Cubillo, Mehmet Gurdal, Dimitrios I Zeugoli. Corneal fibrosis: From in vitro models to current and upcoming drug and gene medicines. Advanced drug delivery reviews. 2024-04-20. PMID:38642593. |
the cornea, the transparent tissue located on the anterior chamber of the eye, is extremely susceptible to fibrotic diseases, which cause loss of corneal transparency and are often associated with blindness. |
2024-04-20 |
2024-04-23 |
Not clear |
| Priyadarshini Sathe, Velmurugan Kailasam, Vasagiri Nagarjuna, Hanuman Sharma, Thirumurthy Velpandian, Prashant Garg, Jayabalan Nirma. Nanomicelles empower natamycin in treating fungal keratitis: An in vitro, ex vivo and in vivo study. International journal of pharmaceutics. 2024-04-14. PMID:38615806. |
fungal infections of cornea are important causes of blindness in developing nations with tropical climate. |
2024-04-14 |
2024-04-17 |
Not clear |
| Safieh Borouman, Faraz Sigaroodi, Seyed Mohsen Ahmadi Tafti, Keyvan Khoshmaram, Masoud Soleimani, Mohammad-Mehdi Khan. ECM-based bioadhesive hydrogel for sutureless repair of deep anterior corneal defects. Biomaterials science. 2024-03-18. PMID:38497791. |
corneal transplantation is the gold standard treatment for corneal-related blindness; however, this strategy faces challenges such as limited donor cornea, graft rejection, suture-related complications, and the need for specialized equipment and advanced surgical skills. |
2024-03-18 |
2024-03-20 |
cattle |
| b' Paula Puistola, Susanna Miettinen, Heli Skottman, Anni M\\xc3\\xb6r\\xc3\\xb. Novel strategy for multi-material 3D bioprinting of human stem cell based corneal stroma with heterogenous design. Materials today. Bio. vol 24. 2024-01-16. PMID:38226015.' |
the human cornea is the transparent outer layer of your eye, and vision loss due to corneal blindness has serious effects on the quality of life of individuals. |
2024-01-16 |
2024-01-18 |
human |
| Shen Liu, Qiang Bai, Yujie Jiang, Yonghui Gao, Zhen Chen, Limin Shang, Siying Zhang, Linrong Yu, Dongqin Yang, Ning Sui, Zhiling Zh. Multienzyme-Like Nanozyme Encapsulated Ocular Microneedles for Keratitis Treatment. Small (Weinheim an der Bergstrasse, Germany). 2023-12-15. PMID:38098457. |
keratitis, an inflammation of the cornea caused by bacterial or fungal infections, is one of the leading causes of severe visual disability and blindness. |
2023-12-15 |
2023-12-17 |
Not clear |
| Konstantin Feinberg, Kiana Tajdaran, Kaveh Mirmoeini, Simeon C Daeschler, Mario A Henriquez, Katelyn E Stevens, Chilando M Mulenga, Arif Hussain, Pedram Hamrah, Asim Ali, Tessa Gordon, Gregory H Borsche. The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628793. |
corneal clarity is required for vision, and blindness occurs when the cornea becomes opaque. |
2023-08-26 |
2023-09-07 |
Not clear |
| Manisha Acharya, Rakhi Nathawat, Anna Salz, Nea Dierolf, Stefanie Eberhard, Nicola Hofmann, Martin Börgel, Virender Sangwan, Surender Dixi. P25-A123 Indo - German GIZ collaboration - impact and way forward in global eye banking. BMJ open ophthalmology. vol 8. issue Suppl 2. 2023-08-21. PMID:37604534. |
most countries of south asia particularly india suffer from donor cornea shortage which limits the number of keratoplasties, thereby aggravating the already high burden of removable blindness. |
2023-08-21 |
2023-09-07 |
Not clear |
| Arun J Thirunavukarasu, Evelina Han, Anu Maashaa Nedumaran, Arthur C Kurz, Jeremy Shuman, Nur Zahirah Binte M Yusoff, Yu-Chi Liu, Valencia Foo, Bertrand Czarny, Andri K Riau, Jodhbir S Meht. Electron beam-irradiated donor cornea for on-demand lenticule implantation to treat corneal diseases and refractive error. Acta biomaterialia. 2023-08-02. PMID:37532130. |
the cornea is the major contributor to the refractive power of the eye, and corneal diseases are a leading cause of reversible blindness. |
2023-08-02 |
2023-08-14 |
human |