Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zahra Karimi, Asadollah Zarifkar, Esmaeil Mirzaei, Mehdi Dianatpour, Mahintaj Dara, Hadi Alighol. Therapeutic effects of nanosilibinin in valproic acid-zebrafish model of autism spectrum disorder: Focusing on Wnt signaling pathway and autism spectrum disorder-related cytokines. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-07-04. PMID:38961588. |
therapeutic effects of nanosilibinin in valproic acid-zebrafish model of autism spectrum disorder: focusing on wnt signaling pathway and autism spectrum disorder-related cytokines. |
2024-07-04 |
2024-07-10 |
zebrafish |
Zahra Karimi, Asadollah Zarifkar, Esmaeil Mirzaei, Mehdi Dianatpour, Mahintaj Dara, Hadi Alighol. Therapeutic effects of nanosilibinin in valproic acid-zebrafish model of autism spectrum disorder: Focusing on Wnt signaling pathway and autism spectrum disorder-related cytokines. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-07-04. PMID:38961588. |
in this study, we delved into the intricate world of autism spectrum disorder (asd) and its connection to the disturbance in the wnt signaling pathway and immunological abnormalities. |
2024-07-04 |
2024-07-10 |
zebrafish |
Sweety Mehra, Aitizaz Ul Ahsan, Madhu Sharma, Muskan Budhwar, Mani Chopr. Gestational Fisetin Exerts Neuroprotection by Regulating Mitochondria-Directed Canonical Wnt Signaling, BBB Integrity, and Apoptosis in Prenatal VPA-Induced Rodent Model of Autism. Molecular neurobiology. 2023-12-04. PMID:38048031. |
numerous investigations in this field investigated the role of canonical wnt signaling cascade in regulating the pathophysiology of autism. |
2023-12-04 |
2023-12-10 |
Not clear |
Sweety Mehra, Aitizaz Ul Ahsan, Madhu Sharma, Muskan Budhwar, Mani Chopr. Gestational Fisetin Exerts Neuroprotection by Regulating Mitochondria-Directed Canonical Wnt Signaling, BBB Integrity, and Apoptosis in Prenatal VPA-Induced Rodent Model of Autism. Molecular neurobiology. 2023-12-04. PMID:38048031. |
gestational fisetin exerts neuroprotection by regulating mitochondria-directed canonical wnt signaling, bbb integrity, and apoptosis in prenatal vpa-induced rodent model of autism. |
2023-12-04 |
2023-12-10 |
Not clear |
Sweety Mehra, Aitizaz Ul Ahsan, Madhu Sharma, Muskan Budhwar, Mani Chopr. Gestational Fisetin Exerts Neuroprotection by Regulating Mitochondria-Directed Canonical Wnt Signaling, BBB Integrity, and Apoptosis in Prenatal VPA-Induced Rodent Model of Autism. Molecular neurobiology. 2023-12-04. PMID:38048031. |
collectively, our findings revealed that fisetin-evoked modulation of the wnt signaling cascade successfully relieved the associated symptoms of autism along with developmental delays in the model and indicates its potential as a bioceutical against autism. |
2023-12-04 |
2023-12-10 |
Not clear |
Justin M Wolter, Jessica A Jimenez, Jason L Stein, Mark J Zylk. ToxCast chemical library Wnt screen identifies diethanolamine as an activator of neural progenitor proliferation. FASEB bioAdvances. vol 4. issue 7. 2022-07-11. PMID:35812078. |
numerous autism spectrum disorder (asd) risk genes are associated with wnt signaling, suggesting that brain development may be especially sensitive to genetic perturbation of this pathway. |
2022-07-11 |
2023-08-14 |
Not clear |
Michael S Breen, Andrew Browne, Gabriel E Hoffman, Sofia Stathopoulos, Kristen Brennand, Joseph D Buxbaum, Elodie Drapea. Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism. Molecular autism. vol 11. issue 1. 2021-08-03. PMID:32560742. |
transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered wnt signaling in phelan-mcdermid syndrome and autism. |
2021-08-03 |
2023-08-13 |
Not clear |
Seung Min Bae, Ji Yeon Hon. The Wnt Signaling Pathway and Related Therapeutic Drugs in Autism Spectrum Disorder. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 16. issue 2. 2020-09-30. PMID:29739125. |
the wnt signaling pathway and related therapeutic drugs in autism spectrum disorder. |
2020-09-30 |
2023-08-13 |
Not clear |
Kimberly A Mulligan, Benjamin N R Cheyett. Neurodevelopmental Perspectives on Wnt Signaling in Psychiatry. Molecular neuropsychiatry. vol 2. issue 4. 2020-09-29. PMID:28277568. |
mounting evidence indicates that wnt signaling is relevant to pathophysiology of diverse mental illnesses including schizophrenia, bipolar disorder, and autism spectrum disorder. |
2020-09-29 |
2023-08-13 |
human |
Jonathan Michael Alexander, Antonella Pirone, Michele H Jaco. Excessive β-Catenin in Excitatory Neurons Results in Reduced Social and Increased Repetitive Behaviors and Altered Expression of Multiple Genes Linked to Human Autism. Frontiers in synaptic neuroscience. vol 12. 2020-09-28. PMID:32296324. |
our findings provide critical new insights into β-cat, wnt pathway dysregulation in the brain causing behavioral phenotypes relevant to the disease and the molecular etiology which includes several human autism risk genes. |
2020-09-28 |
2023-08-13 |
mouse |
Wanxia Yao, Junting Huang, Hongling H. Over-expressed LOC101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the Wnt signaling pathway by targeting FZD3. Cellular signalling. vol 62. 2020-08-20. PMID:31145996. |
over-expressed loc101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the wnt signaling pathway by targeting fzd3. |
2020-08-20 |
2023-08-13 |
rat |
Wanxia Yao, Junting Huang, Hongling H. Over-expressed LOC101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the Wnt signaling pathway by targeting FZD3. Cellular signalling. vol 62. 2020-08-20. PMID:31145996. |
our findings illustrate that up-regulated loc101927196 attenuated oxidative stress disorder in a rat model of autism through suppressing the activation of wnt signaling pathway by targeting fzd3. |
2020-08-20 |
2023-08-13 |
rat |
Wanxia Yao, Junting Huang, Hongling H. Over-expressed LOC101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the Wnt signaling pathway by targeting FZD3. Cellular signalling. vol 62. 2020-08-20. PMID:31145996. |
in addition, loc101927196 targeting fzd3 played a vital role in a rat model of autism through the wnt signaling pathway. |
2020-08-20 |
2023-08-13 |
rat |
Wanxia Yao, Junting Huang, Hongling H. Corrigendum to ' Over-expressed LOC101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the Wnt signaling pathway by targeting FZD3'. Cellular signalling. vol 64. 2020-04-23. PMID:31471214. |
corrigendum to ' over-expressed loc101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the wnt signaling pathway by targeting fzd3'. |
2020-04-23 |
2023-08-13 |
rat |
Vickie Kwan, Brianna K Unda, Karun K Sing. Wnt signaling networks in autism spectrum disorder and intellectual disability. Journal of neurodevelopmental disorders. vol 8. 2019-11-20. PMID:27980692. |
wnt signaling networks in autism spectrum disorder and intellectual disability. |
2019-11-20 |
2023-08-13 |
Not clear |
A Packe. Enrichment of factors regulating canonical Wnt signaling among autism risk genes. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:27956740. |
enrichment of factors regulating canonical wnt signaling among autism risk genes. |
2019-03-12 |
2023-08-13 |
Not clear |
Yinghua Zhang, Weigang Cui, Qianqian Zhai, Tianran Zhang, Xiaojun We. N-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical Wnt pathway in a valproic acid-induced rat model of autism. Molecular medicine reports. vol 16. issue 2. 2018-02-05. PMID:28627665. |
the present study aimed to investigate the effects of nac on the oxidative status of rats in a valproic acid (vpa)‑induced model of autism, and to examine the involvement of the canonical wnt signaling pathway in the actions of nac. |
2018-02-05 |
2023-08-13 |
rat |
Yinghua Zhang, Weigang Cui, Qianqian Zhai, Tianran Zhang, Xiaojun We. N-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical Wnt pathway in a valproic acid-induced rat model of autism. Molecular medicine reports. vol 16. issue 2. 2018-02-05. PMID:28627665. |
n-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical wnt pathway in a valproic acid-induced rat model of autism. |
2018-02-05 |
2023-08-13 |
rat |
Yinghua Zhang, Weigang Cui, Qianqian Zhai, Tianran Zhang, Xiaojun We. N-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical Wnt pathway in a valproic acid-induced rat model of autism. Molecular medicine reports. vol 16. issue 2. 2018-02-05. PMID:28627665. |
the present findings suggested that the beneficial effects of nac in autism may be associated with its antioxidative properties, and may not be mediated by the canonical wnt pathway. |
2018-02-05 |
2023-08-13 |
rat |
Yinghua Zhang, Xiangshan Yuan, Zhongping Wang, Ruixi L. The canonical Wnt signaling pathway in autism. CNS & neurological disorders drug targets. vol 13. issue 5. 2015-03-09. PMID:24365182. |
given its various functions, dysfunction of the canonical wnt pathway may exert adverse effects on neurodevelopment and therefore leads to the pathogenesis of autism. |
2015-03-09 |
2023-08-12 |
human |