Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Nicholas Hoy, Samantha J Lynch, Monika A Waszczuk, Simone Reppermund, Louise Mewto. Transdiagnostic Biomarkers of Mental Illness Across the Lifespan: A Systematic Review Examining the Genetic and Neural Correlates of Latent Transdiagnostic Dimensions of Psychopathology in the General Population. Neuroscience and biobehavioral reviews. 2023-10-28. PMID:37898444. |
the results revealed several biological correlates consistently associated with transdiagnostic dimensions of psychopathology, including polygenic scores for adhd and neuroticism, global surface area and global gray matter volume. |
2023-10-28 |
2023-11-08 |
Not clear |
Angela Lupattelli, Nhung T H Trinh, Hedvig Norden. Association of maternal personality traits with medication use during pregnancy to appraise unmeasured confounding in long-term pharmacoepidemiological safety studies. Frontiers in pharmacology. vol 14. 2023-05-31. PMID:37256227. |
this study aimed to (i) estimate the association between five maternal personality traits and prenatal use of acetaminophen (including extended use), opioid analgesics, antidepressants, benzodiazepines/z-hypnotics, and antipsychotics; (ii) evaluate, using an applied example, whether unmeasured confounding by maternal neuroticism would make the association between prenatal antidepressant-child adhd null, using the e-value framework. |
2023-05-31 |
2023-08-14 |
Not clear |
Jean-Baptiste Pingault, Wikus Barkhuizen, Biyao Wang, Laurie J Hannigan, Espen Moen Eilertsen, Elizabeth Corfield, Ole A Andreassen, Helga Ask, Martin Tesli, Ragna Bugge Askeland, George Davey Smith, Camilla Stoltenberg, Neil M Davies, Ted Reichborn-Kjennerud, Eivind Ystrom, Alexandra Havdah. Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study. Molecular psychiatry. 2022-11-17. PMID:36385167. |
polygenic scores were calculated for parental factors previously associated with adhd, including psychopathology, substance use, neuroticism, educational attainment, and cognitive performance. |
2022-11-17 |
2023-08-14 |
Not clear |
Wonuola A Akingbuwa, Anke R Hammerschlag, Andrea G Allegrini, Hannah Sallis, Ralf Kuja-Halkola, Kaili Rimfeld, Paul Lichtenstein, Sebastian Lundstrom, Marcus R Munaf\\xc3\\xb2, Robert Plomin, Michel G Nivard, Meike Bartels, Christel M Middeldor. Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2022-11-16. PMID:36380638. |
using a multivariate multivariable regression, we analyzed associations of childhood attention-deficit/hyperactivity disorder (adhd), internalizing, and social problems, with polygenic scores (pgs) of adult disorders and traits including major depression, bipolar disorder, subjective well-being, neuroticism, insomnia, educational attainment, and body mass index (bmi), derived for 20,539 children aged 8.5-10.5\xe2\x80\x89years. |
2022-11-16 |
2023-08-14 |
Not clear |
Wonuola A Akingbuwa, Anke R Hammerschlag, Andrea G Allegrini, Hannah Sallis, Ralf Kuja-Halkola, Kaili Rimfeld, Paul Lichtenstein, Sebastian Lundstrom, Marcus R Munaf\\xc3\\xb2, Robert Plomin, Michel G Nivard, Meike Bartels, Christel M Middeldor. Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2022-11-16. PMID:36380638. |
in addition, bmi pgs were associated with adhd symptoms and social problems, while neuroticism pgs were only associated with internalizing problems and educational attainment pgs were only associated with adhd symptoms. |
2022-11-16 |
2023-08-14 |
Not clear |
Gabriela Pessin Meyer, Bruna Santos da Silva, Cibele Edom Bandeira, Maria Eduarda Araujo Tavares, Renata Basso Cupertino, Eduarda Pereira Oliveira, Diana M\\xc3\\xbcller, Djenifer B Kappel, Stefania Pigatto Teche, Eduardo Schneider Vitola, Luis Augusto Rohde, Diego Luiz Rovaris, Eugenio Horacio Grevet, Claiton Henrique Dotto Ba. Dissecting the cross-trait effects of the FOXP2 GWAS hit on clinical and brain phenotypes in adults with ADHD. European archives of psychiatry and clinical neuroscience. 2022-03-13. PMID:35279744. |
it is especially represented among gwas hits for neurodevelopmental disorders and related traits, including attention-deficit/hyperactivity disorder (adhd), autism spectrum disorder, neuroticism, and risk-taking behaviors. |
2022-03-13 |
2023-08-13 |
human |
Robert D Shura, Kevin W Richard, Sarah L Martindale, Timothy W Brearly, Katherine H Taber, Will H Can. Internalizing and externalizing comorbidity and symptom burden in a VA ADHD specialty evaluation clinic. Psychiatry research. vol 309. 2022-01-20. PMID:35051878. |
however, compared to a subsample with no psychiatric diagnoses, individuals diagnosed with adhd endorsed significantly more internalizing symptom burden, with combined adhd veterans also endorsing significantly greater levels of negative emotions and neuroticism. |
2022-01-20 |
2023-08-13 |
human |
Samantha J Lynch, Matthew Sunderland, Nicola C Newton, Cath Chapma. A systematic review of transdiagnostic risk and protective factors for general and specific psychopathology in young people. Clinical psychology review. vol 87. 2021-10-25. PMID:33992846. |
results revealed several biological (executive functioning deficits, earlier pubertal timing, genetic risk for adhd and schizophrenia, reduced gray matter volume), socio-environmental (stressful life events, maternal depression) and psychological (low effortful control, high neuroticism, negative affectivity) transdiagnostic risk factors for broad psychopathology outcomes, including general psychopathology, internalising and externalising. |
2021-10-25 |
2023-08-13 |
Not clear |
Tatiana Polushina, Niladri Banerjee, Sudheer Giddaluru, Francesco Bettella, Thomas Espeseth, Astri J Lundervold, Srdjan Djurovic, Sven Cichon, Per Hoffmann, Markus M N\\xc3\\xb6then, Vidar M Steen, Ole A Andreassen, St\\xc3\\xa9phanie Le Hellar. Identification of pleiotropy at the gene level between psychiatric disorders and related traits. Translational psychiatry. vol 11. issue 1. 2021-08-02. PMID:34326310. |
here, we aimed to identify genetic overlaps at the gene level between 7 mental disorders (schizophrenia, autism spectrum disorder, major depressive disorder, anorexia nervosa, adhd, bipolar disorder and anxiety), 8 brain morphometric traits, 2 cognitive traits (educational attainment and general cognitive function) and 9 personality traits (subjective well-being, depressive symptoms, neuroticism, extraversion, openness to experience, agreeableness and conscientiousness, children's aggressive behaviour, loneliness) based on publicly available gwass. |
2021-08-02 |
2023-08-13 |
Not clear |
Andrew Ratanatharathorn, Karestan C Koenen, Lori B Chibnik, Marc G Weisskopf, Janet W Rich-Edwards, Andrea L Robert. Polygenic risk for autism, attention-deficit hyperactivity disorder, schizophrenia, major depressive disorder, and neuroticism is associated with the experience of childhood abuse. Molecular psychiatry. vol 26. issue 5. 2021-06-11. PMID:33483690. |
using polygenic risk scores for six psychiatric disorders-attention-deficit hyperactivity disorder (adhd), autism spectrum disorder (asd), bipolar disorder (bpd), major depressive disorder (mdd), neuroticism, and schizophrenia-we tested whether genetic risk for mental illness was associated with increased risk of experiencing three types of childhood abuse: physical/emotional abuse, physical assault, and sexual abuse, in a cohort of white non-hispanic women (n\xe2\x80\x89=\xe2\x80\x8911,315). |
2021-06-11 |
2023-08-13 |
Not clear |
Andrew Ratanatharathorn, Karestan C Koenen, Lori B Chibnik, Marc G Weisskopf, Janet W Rich-Edwards, Andrea L Robert. Polygenic risk for autism, attention-deficit hyperactivity disorder, schizophrenia, major depressive disorder, and neuroticism is associated with the experience of childhood abuse. Molecular psychiatry. vol 26. issue 5. 2021-06-11. PMID:33483690. |
adhd and mdd genetic risk scores were associated with a higher risk of experiencing each type of childhood abuse, while neuroticism, schizophrenia, bpd, and asd genetic scores were associated with a higher risk of experiencing physical/emotional abuse and physical assault, but not sexual abuse. |
2021-06-11 |
2023-08-13 |
Not clear |
Tessa F Blanken, Oph\\xc3\\xa9lie Courbet, Nathalie Franc, Ariadna Albajara S\\xc3\\xa1enz, Eus J W Van Someren, Philippe Peigneux, Thomas Villemontei. Is an irritable ADHD profile traceable using personality dimensions? Replicability, stability, and predictive value over time of data-driven profiles. European child & adolescent psychiatry. vol 30. issue 4. 2021-04-29. PMID:32399809. |
three personality profiles were detected: the first two profiles had high levels of neuroticism, with the first displaying higher adhd severity and lower openness to experience (profile 1; n\xe2\x80\x89=\xe2\x80\x8938), and the second lower agreeableness (profile 2; n\xe2\x80\x89=\xe2\x80\x8973). |
2021-04-29 |
2023-08-13 |
Not clear |
Roxanna Korologou-Linden, Genevieve M Leyden, Caroline L Relton, Rebecca C Richmond, Tom G Richardso. Multi-omics analyses of cognitive traits and psychiatric disorders highlights brain-dependent mechanisms. Human molecular genetics. 2021-01-22. PMID:33481009. |
we have applied the principles of mendelian randomization (mr) to investigate whether brain-derived gene expression (n\xe2\x80\x89=\xe2\x80\x891194) may be responsible for mediating the effect of genetic variants on eight cognitive and psychological outcomes (attention deficit hyperactivity disorder (adhd), alzheimer's disease, bipolar disorder, depression, intelligence, insomnia, neuroticism and schizophrenia). |
2021-01-22 |
2023-08-13 |
Not clear |
Guillermo Perez Algorta, Heather A MacPherson, L Eugene Arnold, Stephen P Hinshaw, Lily Hechtman, Margaret H Sibley, Elizabeth B Owen. Maternal personality traits moderate treatment response in the Multimodal Treatment Study of attention-deficit/hyperactivity disorder. European child & adolescent psychiatry. vol 29. issue 11. 2020-11-30. PMID:31863182. |
some mothers of children with attention-deficit/hyperactivity disorder (adhd) present with maladaptive personality profiles (high neuroticism, low conscientiousness). |
2020-11-30 |
2023-08-13 |
Not clear |
Guillermo Perez Algorta, Heather A MacPherson, L Eugene Arnold, Stephen P Hinshaw, Lily Hechtman, Margaret H Sibley, Elizabeth B Owen. Maternal personality traits moderate treatment response in the Multimodal Treatment Study of attention-deficit/hyperactivity disorder. European child & adolescent psychiatry. vol 29. issue 11. 2020-11-30. PMID:31863182. |
we evaluate whether maternal neuroticism and conscientiousness moderated response in the multimodal treatment study of children with adhd. |
2020-11-30 |
2023-08-13 |
Not clear |
Michelle M Martel, Monica L Gremillion, Jennifer L Tacket. Personality Traits Elucidate Sex Differences in Attention-Deficit/Hyperactivity Disorder Comorbidity During Early Childhood. Journal of psychopathology and behavioral assessment. vol 36. issue 2. 2020-10-01. PMID:25598574. |
while high neuroticism mediated associations between adhd and oppositional-defiance in girls, disagreeableness mediated associations between adhd and aggression and low conscientiousness mediated associations between adhd and neurodevelopmental language problems in boys. |
2020-10-01 |
2023-08-13 |
human |
Virginia Krieger, Juan Antonio Amador-Campos, Joan Gu\\xc3\\xa0rdia-Olmo. Executive functions, Personality traits and ADHD symptoms in adolescents: A mediation analysis. PloS one. vol 15. issue 5. 2020-07-31. PMID:32374779. |
adolescents with adhd had lower scores than control participants on conscientiousness and agreeableness, and higher scores on neuroticism. |
2020-07-31 |
2023-08-13 |
human |
Ting Li, Nina R Mota, Tessel E Galesloot, Janita Bralten, Jan K Buitelaar, Joanna IntHout, Alejandro AriasVasquez, Barbara Frank. ADHD symptoms in the adult general population are associated with factors linked to ADHD in adult patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 10. 2020-07-14. PMID:31378654. |
partial spearman correlation and hurdle negative binomial regression analysis were used to assess how age, sex, childhood adhd symptoms, anxiety symptoms, and personality traits (neuroticism, extraversion, and psychoticism) are associated with current ia and hi symptoms. |
2020-07-14 |
2023-08-13 |
human |
Ting Li, Nina R Mota, Tessel E Galesloot, Janita Bralten, Jan K Buitelaar, Joanna IntHout, Alejandro AriasVasquez, Barbara Frank. ADHD symptoms in the adult general population are associated with factors linked to ADHD in adult patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 10. 2020-07-14. PMID:31378654. |
childhood adhd symptoms, neuroticism, and psychoticism were positively associated with current ia and hi symptoms, while extraversion had an opposite association with these symptom domains. |
2020-07-14 |
2023-08-13 |
human |
David Williamson, Charlotte Johnsto. Maternal ADHD Symptoms and Parenting Stress: The Roles of Parenting Self-Efficacy Beliefs and Neuroticism. Journal of attention disorders. vol 23. issue 5. 2020-06-26. PMID:28201945. |
maternal adhd symptoms and parenting stress: the roles of parenting self-efficacy beliefs and neuroticism. |
2020-06-26 |
2023-08-13 |
Not clear |