| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoonjung Yoonie Joo, Eunji Lee, Bo-Gyeom Kim, Gakyung Kim, Jungwoo Seo, Jiook Ch. Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children. bioRxiv : the preprint server for biology. 2024-06-03. PMID:38826224. |
conversely, negative associations were found with the gpss of adhd, depression and neuroticism. |
2024-06-03 |
2024-06-05 |
human |
| Laura J Bell, Oliver P John, Stephen P Hinsha. ADHD Symptoms in Childhood and Big Five Personality Traits in Adolescence: A Five-Year Longitudinal Study in Girls. Research on child and adolescent psychopathology. 2024-05-29. PMID:38809446. |
as expected, childhood adhd diagnosis prospectively predicted lower self-reported conscientiousness, lower agreeableness, and higher neuroticism in adolescence. |
2024-05-29 |
2024-06-03 |
Not clear |
| Laura J Bell, Oliver P John, Stephen P Hinsha. ADHD Symptoms in Childhood and Big Five Personality Traits in Adolescence: A Five-Year Longitudinal Study in Girls. Research on child and adolescent psychopathology. 2024-05-29. PMID:38809446. |
with adhd diagnosis covaried, inattention (ia) predicted only low conscientiousness, hyperactivity/impulsivity (hi) predicted only low agreeableness, and neither predicted adolescent neuroticism. |
2024-05-29 |
2024-06-03 |
Not clear |
| Elham Assary, Jonathan Coleman, Gibran Hemani, Margot van Der Veijer, Laurence Howe, Teemu Palviainen, Katrina Grasby, Rafael Ahlskog, Marianne Nygaard, Rosa Cheesman, Kai Lim, Chandra Reynolds, Juan Ordoñana, Lucia Colodro-Conde, Scott Gordon, Juan Madrid-Valero, Anbupalam Thalamuthu, Jouke-Jan Hottenga, Jonas Mengel-From, Nicola J Armstrong, Perminder Sachdev, Teresa Lee, Henry Brodaty, Julian Trollor, Margaret Wright, David Ames, Vibeke Catts, Antti Latvala, Eero Vuoksimaa, Travis Mallard, K Harden, Elliot Tucker-Drob, Sven Oskarsson, Christopher Hammond, Kaare Christensen, Mark Taylor, Sebastian Lundström, Henrik Larsson, Robert Karlsson, Nancy Pedersen, Karen Mather, Sarah Medland, D Boomsma, Nicholas Martin, Robert Plomin, Meike Bartels, Paul Lichtenstein, Jaakko Kaprio, Thalia Eley, Neil Davies, Patricia Munroe, Robert Keer. Genetics of environmental sensitivity to psychiatric and neurodevelopmental phenotypes: evidence from GWAS of monozygotic twins. Research square. 2024-05-24. PMID:38746362. |
we combined data from up to 21,792 monozygotic twins (10,896 pairs) from 11 studies to conduct the largest gwas meta-analysis of monozygotic phenotypic differences in children and adolescents/adults for seven psychiatric and neurodevelopmental phenotypes: attention deficit hyperactivity disorder (adhd) symptoms, autistic traits, anxiety and depression symptoms, psychotic-like experiences, neuroticism, and wellbeing. |
2024-05-24 |
2024-05-27 |
Not clear |
| Jacob J Crouse, Shin Ho Park, Enda M Byrne, Brittany L Mitchell, Jan Scott, Sarah E Medland, Tian Lin, Naomi R Wray, Nicholas G Martin, Ian B Hicki. Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. Molecular psychiatry. 2024-04-04. PMID:38575805. |
in the australian genetics of depression study (n = 14,146; 75% female), we tested whether polygenic scores (pgs) for major depression, bipolar disorder, schizophrenia, anxiety, adhd, and neuroticism were associated with reported exposure to 32 childhood, past-year, lifetime, and accumulated stressful life events (sles). |
2024-04-04 |
2024-04-07 |
Not clear |
| Andrew Ratanatharathorn, Luwei Quan, Karestan C Koenen, Lori B Chibnik, Marc G Weisskopf, Natalie Slopen, Andrea L Robert. Polygenic risk for major depression, attention deficit hyperactivity disorder, neuroticism, and schizophrenia are correlated with experience of intimate partner violence. Translational psychiatry. vol 14. issue 1. 2024-02-28. PMID:38409192. |
using polygenic risk scores for six psychiatric disorders - attention-deficit hyperactivity disorder (adhd), autism spectrum disorder (asd), bipolar disorder (bpd), major depressive disorder (mdd), neuroticism, and schizophrenia-and a combined measure of overall genetic risk for mental illness, we tested whether women's genetic risk for mental illness was associated with the experience of three types of intimate partner violence. |
2024-02-28 |
2024-03-01 |
human |
| Andrew Ratanatharathorn, Luwei Quan, Karestan C Koenen, Lori B Chibnik, Marc G Weisskopf, Natalie Slopen, Andrea L Robert. Polygenic risk for major depression, attention deficit hyperactivity disorder, neuroticism, and schizophrenia are correlated with experience of intimate partner violence. Translational psychiatry. vol 14. issue 1. 2024-02-28. PMID:38409192. |
in this cohort of women of european ancestry (n = 11,095), participants in the highest quintile of genetic risk for adhd (or range: 1.38-1.49), mdd (or range: 1.28-1.43), neuroticism (or range: (1.18-1.25), schizophrenia (or range: 1.30-1.34), and overall genetic risk (or range: 1.30-1.41) were at higher risk for experiencing more severe emotional and physical abuse, and, except schizophrenia, more severe sexual abuse, as well as more types of abuse and chronic abuse. |
2024-02-28 |
2024-03-01 |
human |
| Nicholas Hoy, Samantha J Lynch, Monika A Waszczuk, Simone Reppermund, Louise Mewto. Transdiagnostic Biomarkers of Mental Illness Across the Lifespan: A Systematic Review Examining the Genetic and Neural Correlates of Latent Transdiagnostic Dimensions of Psychopathology in the General Population. Neuroscience and biobehavioral reviews. 2023-10-28. PMID:37898444. |
the results revealed several biological correlates consistently associated with transdiagnostic dimensions of psychopathology, including polygenic scores for adhd and neuroticism, global surface area and global gray matter volume. |
2023-10-28 |
2023-11-08 |
Not clear |
| Angela Lupattelli, Nhung T H Trinh, Hedvig Norden. Association of maternal personality traits with medication use during pregnancy to appraise unmeasured confounding in long-term pharmacoepidemiological safety studies. Frontiers in pharmacology. vol 14. 2023-05-31. PMID:37256227. |
this study aimed to (i) estimate the association between five maternal personality traits and prenatal use of acetaminophen (including extended use), opioid analgesics, antidepressants, benzodiazepines/z-hypnotics, and antipsychotics; (ii) evaluate, using an applied example, whether unmeasured confounding by maternal neuroticism would make the association between prenatal antidepressant-child adhd null, using the e-value framework. |
2023-05-31 |
2023-08-14 |
Not clear |
| Jean-Baptiste Pingault, Wikus Barkhuizen, Biyao Wang, Laurie J Hannigan, Espen Moen Eilertsen, Elizabeth Corfield, Ole A Andreassen, Helga Ask, Martin Tesli, Ragna Bugge Askeland, George Davey Smith, Camilla Stoltenberg, Neil M Davies, Ted Reichborn-Kjennerud, Eivind Ystrom, Alexandra Havdah. Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study. Molecular psychiatry. 2022-11-17. PMID:36385167. |
polygenic scores were calculated for parental factors previously associated with adhd, including psychopathology, substance use, neuroticism, educational attainment, and cognitive performance. |
2022-11-17 |
2023-08-14 |
Not clear |
| Wonuola A Akingbuwa, Anke R Hammerschlag, Andrea G Allegrini, Hannah Sallis, Ralf Kuja-Halkola, Kaili Rimfeld, Paul Lichtenstein, Sebastian Lundstrom, Marcus R Munafò, Robert Plomin, Michel G Nivard, Meike Bartels, Christel M Middeldor. Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2022-11-16. PMID:36380638. |
using a multivariate multivariable regression, we analyzed associations of childhood attention-deficit/hyperactivity disorder (adhd), internalizing, and social problems, with polygenic scores (pgs) of adult disorders and traits including major depression, bipolar disorder, subjective well-being, neuroticism, insomnia, educational attainment, and body mass index (bmi), derived for 20,539 children aged 8.5-10.5 years. |
2022-11-16 |
2023-08-14 |
Not clear |
| Wonuola A Akingbuwa, Anke R Hammerschlag, Andrea G Allegrini, Hannah Sallis, Ralf Kuja-Halkola, Kaili Rimfeld, Paul Lichtenstein, Sebastian Lundstrom, Marcus R Munafò, Robert Plomin, Michel G Nivard, Meike Bartels, Christel M Middeldor. Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2022-11-16. PMID:36380638. |
in addition, bmi pgs were associated with adhd symptoms and social problems, while neuroticism pgs were only associated with internalizing problems and educational attainment pgs were only associated with adhd symptoms. |
2022-11-16 |
2023-08-14 |
Not clear |
| Gabriela Pessin Meyer, Bruna Santos da Silva, Cibele Edom Bandeira, Maria Eduarda Araujo Tavares, Renata Basso Cupertino, Eduarda Pereira Oliveira, Diana Müller, Djenifer B Kappel, Stefania Pigatto Teche, Eduardo Schneider Vitola, Luis Augusto Rohde, Diego Luiz Rovaris, Eugenio Horacio Grevet, Claiton Henrique Dotto Ba. Dissecting the cross-trait effects of the FOXP2 GWAS hit on clinical and brain phenotypes in adults with ADHD. European archives of psychiatry and clinical neuroscience. 2022-03-13. PMID:35279744. |
it is especially represented among gwas hits for neurodevelopmental disorders and related traits, including attention-deficit/hyperactivity disorder (adhd), autism spectrum disorder, neuroticism, and risk-taking behaviors. |
2022-03-13 |
2023-08-13 |
human |
| Robert D Shura, Kevin W Richard, Sarah L Martindale, Timothy W Brearly, Katherine H Taber, Will H Can. Internalizing and externalizing comorbidity and symptom burden in a VA ADHD specialty evaluation clinic. Psychiatry research. vol 309. 2022-01-20. PMID:35051878. |
however, compared to a subsample with no psychiatric diagnoses, individuals diagnosed with adhd endorsed significantly more internalizing symptom burden, with combined adhd veterans also endorsing significantly greater levels of negative emotions and neuroticism. |
2022-01-20 |
2023-08-13 |
human |
| Samantha J Lynch, Matthew Sunderland, Nicola C Newton, Cath Chapma. A systematic review of transdiagnostic risk and protective factors for general and specific psychopathology in young people. Clinical psychology review. vol 87. 2021-10-25. PMID:33992846. |
results revealed several biological (executive functioning deficits, earlier pubertal timing, genetic risk for adhd and schizophrenia, reduced gray matter volume), socio-environmental (stressful life events, maternal depression) and psychological (low effortful control, high neuroticism, negative affectivity) transdiagnostic risk factors for broad psychopathology outcomes, including general psychopathology, internalising and externalising. |
2021-10-25 |
2023-08-13 |
Not clear |
| Tatiana Polushina, Niladri Banerjee, Sudheer Giddaluru, Francesco Bettella, Thomas Espeseth, Astri J Lundervold, Srdjan Djurovic, Sven Cichon, Per Hoffmann, Markus M Nöthen, Vidar M Steen, Ole A Andreassen, Stéphanie Le Hellar. Identification of pleiotropy at the gene level between psychiatric disorders and related traits. Translational psychiatry. vol 11. issue 1. 2021-08-02. PMID:34326310. |
here, we aimed to identify genetic overlaps at the gene level between 7 mental disorders (schizophrenia, autism spectrum disorder, major depressive disorder, anorexia nervosa, adhd, bipolar disorder and anxiety), 8 brain morphometric traits, 2 cognitive traits (educational attainment and general cognitive function) and 9 personality traits (subjective well-being, depressive symptoms, neuroticism, extraversion, openness to experience, agreeableness and conscientiousness, children's aggressive behaviour, loneliness) based on publicly available gwass. |
2021-08-02 |
2023-08-13 |
Not clear |
| Andrew Ratanatharathorn, Karestan C Koenen, Lori B Chibnik, Marc G Weisskopf, Janet W Rich-Edwards, Andrea L Robert. Polygenic risk for autism, attention-deficit hyperactivity disorder, schizophrenia, major depressive disorder, and neuroticism is associated with the experience of childhood abuse. Molecular psychiatry. vol 26. issue 5. 2021-06-11. PMID:33483690. |
using polygenic risk scores for six psychiatric disorders-attention-deficit hyperactivity disorder (adhd), autism spectrum disorder (asd), bipolar disorder (bpd), major depressive disorder (mdd), neuroticism, and schizophrenia-we tested whether genetic risk for mental illness was associated with increased risk of experiencing three types of childhood abuse: physical/emotional abuse, physical assault, and sexual abuse, in a cohort of white non-hispanic women (n = 11,315). |
2021-06-11 |
2023-08-13 |
Not clear |
| Andrew Ratanatharathorn, Karestan C Koenen, Lori B Chibnik, Marc G Weisskopf, Janet W Rich-Edwards, Andrea L Robert. Polygenic risk for autism, attention-deficit hyperactivity disorder, schizophrenia, major depressive disorder, and neuroticism is associated with the experience of childhood abuse. Molecular psychiatry. vol 26. issue 5. 2021-06-11. PMID:33483690. |
adhd and mdd genetic risk scores were associated with a higher risk of experiencing each type of childhood abuse, while neuroticism, schizophrenia, bpd, and asd genetic scores were associated with a higher risk of experiencing physical/emotional abuse and physical assault, but not sexual abuse. |
2021-06-11 |
2023-08-13 |
Not clear |
| Tessa F Blanken, Ophélie Courbet, Nathalie Franc, Ariadna Albajara Sáenz, Eus J W Van Someren, Philippe Peigneux, Thomas Villemontei. Is an irritable ADHD profile traceable using personality dimensions? Replicability, stability, and predictive value over time of data-driven profiles. European child & adolescent psychiatry. vol 30. issue 4. 2021-04-29. PMID:32399809. |
three personality profiles were detected: the first two profiles had high levels of neuroticism, with the first displaying higher adhd severity and lower openness to experience (profile 1; n = 38), and the second lower agreeableness (profile 2; n = 73). |
2021-04-29 |
2023-08-13 |
Not clear |
| Roxanna Korologou-Linden, Genevieve M Leyden, Caroline L Relton, Rebecca C Richmond, Tom G Richardso. Multi-omics analyses of cognitive traits and psychiatric disorders highlights brain-dependent mechanisms. Human molecular genetics. 2021-01-22. PMID:33481009. |
we have applied the principles of mendelian randomization (mr) to investigate whether brain-derived gene expression (n = 1194) may be responsible for mediating the effect of genetic variants on eight cognitive and psychological outcomes (attention deficit hyperactivity disorder (adhd), alzheimer's disease, bipolar disorder, depression, intelligence, insomnia, neuroticism and schizophrenia). |
2021-01-22 |
2023-08-13 |
Not clear |