| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohamed Salih, Reem Mohamed Osman, Wala Alim, Leena Khalid, Wafa Sosal, Danya Ibrahim, Yassir Mahgou. Agitated Depression Associated With Flurazepam Discontinuation. Case reports in psychiatry. vol 2024. 2024-09-30. PMID:39345783. |
we describe a case of a 73-year-old female with a prior history of depression and generalized anxiety disorder who was maintained on flurazepam for 44 years and was admitted for severe depression with psychomotor agitation, prominent vegetative symptoms, thought perseveration, indecisiveness, and psychotic features that emerged following the discontinuation of flurazepam. |
2024-09-30 |
2024-10-02 |
Not clear |
| Xilu Jiao, Kevin D Beck, Catherine E Myers, Richard J Servatius, Kevin C H Pan. Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task. Frontiers in behavioral neuroscience. vol 9. 2015-10-07. PMID:26441578. |
together, these data start to identify the key brain regions important in active avoidance behavior, areas that could be associated with avoidance perseveration in anxiety disorders. |
2015-10-07 |
2023-08-13 |
rat |
| Xilu Jiao, Kevin D Beck, Catherine E Myers, Richard J Servatius, Kevin C H Pan. Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task. Frontiers in behavioral neuroscience. vol 9. 2015-10-07. PMID:26441578. |
given that avoidance perseveration represents a core symptom of anxiety disorders, the neural substrate of avoidance, especially its extinction, requires better understanding. |
2015-10-07 |
2023-08-13 |
rat |
| Xilu Jiao, Kevin D Beck, Amanda L Stewart, Ian M Smith, Catherine E Myers, Richard J Servatius, Kevin C H Pan. Effects of psychotropic agents on extinction of lever-press avoidance in a rat model of anxiety vulnerability. Frontiers in behavioral neuroscience. vol 8. 2014-10-13. PMID:25309372. |
avoidance and its perseveration represent key features of anxiety disorders. |
2014-10-13 |
2023-08-13 |
rat |
| R J Servatius, X Jiao, K D Beck, K C H Pang, T R Mino. Rapid avoidance acquisition in Wistar-Kyoto rats. Behavioural brain research. vol 192. issue 2. 2008-09-30. PMID:18501974. |
thus, wky rats have a unique combination of trait behavioral inhibition (low open field activity and stress sensitivity) and superior avoidance acquisition and response perseveration making this strain a good model to understand anxiety disorders. |
2008-09-30 |
2023-08-12 |
rat |