| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam Eckardt, Charles Marble, Bradley Fern, Henry Moritz, Charles Kotula, Jiayi Ke, Clarisse Rebancos, Samantha Robertson, Hiroshi Nishimune, Masatoshi Suzuk. Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS. Frontiers in neuroscience. vol 19. 2025-02-03. PMID:39896335. |
amyotrophic lateral sclerosis (als) is a neuromuscular disease characterized by specific loss of motor neurons in the spinal cord and brain stem. |
2025-02-03 |
2025-02-05 |
rat |
| Prashanth Prakash, Tianhao Lei, Robert D Flint, Jason K Hsieh, Zachary Fitzgerald, Emily Mittag Mugler, Jessica Templer, Matthew A Goldrick, Matthew C Tate, Joshua M Rosenow, Joshua I Glaser, Marc W Slutzk. Decoding speech intent from non-frontal cortical areas. Journal of neural engineering. 2025-01-14. PMID:39808939. |
primarily, these bmis target individuals with intact speech motor cortices but who are paralyzed by disrupted connections between frontal cortices and their articulators due to brainstem stroke or motor neuron diseases such as amyotrophic lateral sclerosis. |
2025-01-14 |
2025-01-17 |
Not clear |
| Jacques A Rousseau, Marcel Maier, Samia Ait-Mohand, Véronique Dumulon-Perreault, Otman Sarrhini, Sébastien Tremblay, Etienne Rousseau, Michael Salzmann, Brigitte Guéri. Antibody-Based PET Imaging of Misfolded Superoxide Dismutase 1 in an Amyotrophic Lateral Sclerosis Mouse Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024-12-12. PMID:39667814. |
amyotrophic lateral sclerosis (als) is a rare neurodegenerative disease characterized by motor neuron loss in the motor cortex, brain stem, and spinal cord. |
2024-12-12 |
2024-12-22 |
mouse |
| Banaja P Dash, Axel Freischmidt, Anika M Helferich, Albert C Ludolph, Peter M Andersen, Jochen H Weishaupt, Andreas Herman. Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patients. Frontiers in cellular neuroscience. vol 18. 2024-11-26. PMID:39588282. |
amyotrophic lateral sclerosis (als) is a fatal, adult-onset disease marked by a progressive degeneration of motor neurons (mns) present in the spinal cord, brain stem and motor cortex. |
2024-11-26 |
2024-11-28 |
Not clear |
| Song Luo, Xiaorui Wang, Bo Ma, Dongliang Liu, Li Li, Lijin Wang, Ning Ding, Liangyu Zou, Jie Wang, Jialin Pan, Daoqian Sang, Huadong Zhou, Hongdang Qu, Yi Lu, Lijuan Yan. Therapeutic potential of Simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation. Biomolecules & biomedicine. 2024-11-21. PMID:39569650. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective death of motor neurons in the spinal cord, brainstem, and motor cortex. |
2024-11-21 |
2024-11-23 |
mouse |
| M Khamaysa, M El Mendili, V Marchand, G Querin, P-F Prada. Quantitative spinal cord imaging: Early ALS diagnosis and monitoring of disease progression. Revue neurologique. 2024-11-15. PMID:39547910. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disorder characterized by the progressive degeneration of motor neurons in the cortex, brainstem, and spinal cord. |
2024-11-15 |
2024-11-18 |
Not clear |
| María Montiel-Troya, Himan Mohamed-Mohamed, Teresa Pardo-Moreno, Ana González-Díaz, Azahara Ruger-Navarrete, Mario de la Mata Fernández, María Isabel Tovar-Gálvez, Juan José Ramos-Rodríguez, Victoria García-Morale. Advancements in Pharmacological Interventions and Novel Therapeutic Approaches for Amyotrophic Lateral Sclerosis. Biomedicines. vol 12. issue 10. 2024-10-26. PMID:39457513. |
(1) amyotrophic lateral sclerosis (als) is a neurodegenerative disease in which the patient suffers from an affection of both upper and lower motor neurons at the spinal and brainstem level, causing a progressive paralysis that leads to the patient's demise. |
2024-10-26 |
2024-10-29 |
Not clear |
| Miguel Angrick, Shiyu Luo, Qinwan Rabbani, Shreya Joshi, Daniel N Candrea, Griffin W Milsap, Chad R Gordon, Kathryn Rosenblatt, Lora Clawson, Nicholas Maragakis, Francesco V Tenore, Matthew S Fifer, Nick F Ramsey, Nathan E Cron. Real-time detection of spoken speech from unlabeled ECoG signals: A pilot study with an ALS participant. medRxiv : the preprint server for health sciences. 2024-10-14. PMID:39371161. |
brain-computer interfaces (bcis) hold significant promise for restoring communication in individuals with partial or complete loss of the ability to speak due to paralysis from amyotrophic lateral sclerosis (als), brainstem stroke, and other neurological disorders. |
2024-10-14 |
2024-10-16 |
human |
| Brigid K Jense. Astrocyte-Neuron Interactions Contributing to Amyotrophic Lateral Sclerosis Progression. Advances in neurobiology. vol 39. 2024-08-27. PMID:39190080. |
amyotrophic lateral sclerosis (als) is a complex disease impacting motor neurons of the brain, brainstem, and spinal cord. |
2024-08-27 |
2024-08-30 |
Not clear |
| Maria Guarnaccia, Giovanna Morello, Valentina La Cognata, Vincenzo La Bella, Francesca Luisa Conforti, Sebastiano Cavallar. Increased copy-number variant load of associated risk genes in sporadic cases of amyotrophic lateral sclerosis. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-07-28. PMID:39066921. |
amyotrophic lateral sclerosis (als) is an age-related neurodegenerative disease characterized by selective loss of motor neurons in the brainstem and spinal cord. |
2024-07-28 |
2024-08-02 |
Not clear |
| Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. |
2024-07-04 |
2024-07-10 |
mouse |
| Ching-Yi Lin, Veronica Vanoverbeke, David Trent, Kathryn Willey, Yu-Shang Le. The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928564. |
the spatiotemporal expression of socs3 in the brainstem and spinal cord of amyotrophic lateral sclerosis mice. |
2024-06-27 |
2024-06-29 |
mouse |
| Marlene Tahedl, Ee Ling Tan, Jana Kleinerova, Siobhan Delaney, Jennifer C Hengeveld, Mark A Doherty, Russell L Mclaughlin, Pierre-Francois Pradat, Cédric Raoul, Fabrice Ango, Orla Hardiman, Kai Ming Chang, Jasmin Lope, Peter Bed. Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis. Neurology. vol 103. issue 2. 2024-06-20. PMID:38900989. |
amyotrophic lateral sclerosis (als) is predominantly associated with motor cortex, corticospinal tract (cst), brainstem, and spinal cord degeneration, and cerebellar involvement is much less well characterized. |
2024-06-20 |
2024-06-23 |
Not clear |
| Ilaria Martinelli, Jessica Mandrioli, Andrea Ghezzi, Elisabetta Zucchi, Giulia Gianferrari, Cecilia Simonini, Francesco Cavallieri, Franco Valzani. Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients: a rare occurrence? Neural regeneration research. vol 20. issue 1. 2024-05-20. PMID:38767482. |
amyotrophic lateral sclerosis (als) is a neuromuscular condition resulting from the progressive degeneration of motor neurons in the cortex, brainstem, and spinal cord. |
2024-05-20 |
2024-05-27 |
human |
| Rumi Ueha, Cathrine Miura, Naoyuki Matsumoto, Taku Sato, Takao Goto, Kenji Kond. Vocal Fold Motion Impairment in Neurodegenerative Diseases. Journal of clinical medicine. vol 13. issue 9. 2024-05-11. PMID:38731036. |
vfmi in ndds is caused by the following: laryngeal muscle weakness due to muscular atrophy, caused by brainstem and motor neuron degeneration in amyotrophic lateral sclerosis; hyperactivity of laryngeal adductors in parkinson's disease; and varying degrees of laryngeal adductor hypertonia and abductor paralysis in multiple system atrophy. |
2024-05-11 |
2024-05-27 |
Not clear |
| Sharon Natasha Cox, Claudio Lo Giudice, Anna Lavecchia, Maria Luana Poeta, Matteo Chiara, Ernesto Picardi, Graziano Pesol. Mitochondrial and Nuclear DNA Variants in Amyotrophic Lateral Sclerosis: Enrichment in the Mitochondrial Control Region and Sirtuin Pathway Genes in Spinal Cord Tissue. Biomolecules. vol 14. issue 4. 2024-04-27. PMID:38672428. |
amyotrophic lateral sclerosis (als) is a progressive disease with prevalent mitochondrial dysfunctions affecting both upper and lower motor neurons in the motor cortex, brainstem, and spinal cord. |
2024-04-27 |
2024-04-29 |
human |
| David Gonzalez, Xiomara Cuenca, Miguel L Allend. Knockdown of Frontiers in cellular neuroscience. vol 18. 2024-04-22. PMID:38644973. |
knockdown of amyotrophic lateral sclerosis (als) corresponds to a neurodegenerative disorder marked by the progressive degeneration of both upper and lower motor neurons located in the brain, brainstem, and spinal cord. |
2024-04-22 |
2024-04-24 |
mouse |
| Makoto Urushitani, Hitoshi Warita, Naoki Atsuta, Yuishin Izumi, Osamu Kano, Toshio Shimizu, Yuki Nakayama, Yugo Narita, Hiroyuki Nodera, Takuji Fujita, Koichi Mizoguchi, Mitsuya Morita, Masashi Aok. The clinical practice guideline for the management of amyotrophic lateral sclerosis in Japan-update 2023. Rinsho shinkeigaku = Clinical neurology. 2024-03-24. PMID:38522911. |
amyotrophic lateral sclerosis (als) is an adult-onset intractable motor neuron disease characterized by selective degeneration of cortical neurons in the frontotemporal lobe and motor neurons in the brainstem and spinal cord. |
2024-03-24 |
2024-03-27 |
Not clear |
| LiJun Zhou, RenShi X. Invertebrate genetic models of amyotrophic lateral sclerosis. Frontiers in molecular neuroscience. vol 17. 2024-03-19. PMID:38500677. |
amyotrophic lateral sclerosis (als) is a common adult-onset neurodegenerative disease characterized by the progressive death of motor neurons in the cerebral cortex, brain stem, and spinal cord. |
2024-03-19 |
2024-03-21 |
human |
| Jelena Scekic-Zahirovic, Cristina Benetton, Aurore Brunet, XiaoQian Ye, Evgeny Logunov, Vincent Douchamps, Salim Megat, Virginie Andry, Vanessa Wing Yin Kan, Geoffrey Stuart-Lopez, Johan Gilet, Simon J Guillot, Sylvie Dirrig-Grosch, Charlotte Gorin, Margaux Trombini, Stéphane Dieterle, Jérôme Sinniger, Mathieu Fischer, Frédérique René, Zeynep Gunes, Pascal Kessler, Luc Dupuis, Pierre-François Pradat, Yannick Goumon, Romain Goutagny, Véronique Marchand-Pauvert, Sabine Liebscher, Caroline Rouau. Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency. Science translational medicine. vol 16. issue 738. 2024-03-13. PMID:38478631. |
amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease, characterized by the death of upper (umn) and lower motor neurons (lmn) in the motor cortex, brainstem, and spinal cord. |
2024-03-13 |
2024-03-16 |
mouse |