| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kang-Fu Yin, Ting Chen, Xiao-Jing Gu, Zheng Jiang, Wei-Ming Su, Qing-Qing Duan, Xiang-Jin Wen, Bei Cao, Ju-Rong Li, Li-Yi Chi, Yong-Ping Che. Identification of Potential Causal Genes for Neurodegenerative Diseases by Mitochondria-Related Genome-Wide Mendelian Randomization. Molecular neurobiology. 2024-09-30. PMID:39347895. |
through the integration of summary statistics from expression quantitative trait loci (eqtl) datasets (human blood and brain tissue), mitochondrial dna copy number (mtdna-cn), and genome-wide association studies (gwas) datasets of five ndds from european ancestry, we conducted a mendelian randomization (mr) analysis to explore the potential causal relationship between mitochondrial-related genes and alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), frontotemporal dementia (ftd), and lewy body dementia (lbd). |
2024-09-30 |
2024-10-02 |
human |
| Xingyu Chen, Li Cai, Weibing Fan, Qian Yang, Xinfa Mao, Liping Ya. Causal relationships between rheumatoid arthritis and neurodegenerative diseases: a two-sample univariable and multivariable Mendelian randomization study. Frontiers in medicine. vol 11. 2024-08-28. PMID:39193017. |
this study employs a two-sample mendelian randomization (mr) approach to assess the causal impact of ra on three nds, including alzheimer's disease (ad), parkinson's disease (pd), and amyotrophic lateral sclerosis (als). |
2024-08-28 |
2024-08-30 |
Not clear |
| Min Wang, Zhiquan Tan. No causal relationship between serum urate and neurodegenerative diseases: A Mendelian randomization study. Experimental gerontology. 2024-07-02. PMID:38955238. |
we employed a two-sample mendelian randomization (mr) approach to assess the causal relationship between serum urate and four common subtypes of nds, including parkinson's disease (pd), alzheimer's disease (ad), amyotrophic lateral sclerosis (als), and multiple sclerosis (ms). |
2024-07-02 |
2024-07-06 |
Not clear |
| Maoqi Chen, Ping Zho. 2CFastICA: A Novel Method for High Density Surface EMG Decomposition Based on Kernel Constrained FastICA and Correlation Constrained FastICA. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol PP. 2024-05-13. PMID:38717875. |
in addition, a different form of two source validation was also conducted taking advantages of the high density surface emg characteristics of patients with amyotrophic lateral sclerosis, showing a mr of (99.4 ± 0.9) % for 34 common motor units from interference and sparse datasets. |
2024-05-13 |
2024-05-27 |
Not clear |
| Yiren Yao, Hongyang Liu, Yang Gu, Xiaojin Xu, Xiwen Zhan. A causal association between amyotrophic lateral sclerosis and atrial fibrillation: a two-sample Mendelian randomization study. Frontiers in cardiovascular medicine. vol 11. 2024-04-26. PMID:38665232. |
to look into the connection between amyotrophic lateral sclerosis (als) and atrial fibrillation (af) using mendelian randomization (mr). |
2024-04-26 |
2024-04-28 |
Not clear |
| Dun Li, Lihui Zhou, Zhi Cao, Jida Wang, Hongxi Yang, Mingqian Lyu, Yuan Zhang, Rongrong Yang, Ju Wang, Yuhong Bian, Weili Xu, Yaogang Wan. Associations of environmental factors with neurodegeneration: An exposome-wide Mendelian randomization investigation. Ageing research reviews. vol 95. 2024-03-03. PMID:38430933. |
in this study, we comprehensively explored the causal associations of the common environmental factors with major ndds including alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), and multiple sclerosis (ms), based on updated large-scale genome-wide association study data through two-sample mendelian randomization (mr) approach. |
2024-03-03 |
2024-03-06 |
Not clear |
| Aiping Fang, Yue Zhao, Ping Yang, Xuehong Zhang, Edward L Giovannucc. Vitamin D and human health: evidence from Mendelian randomization studies. European journal of epidemiology. 2024-01-12. PMID:38214845. |
linear mr analyses showed genetically high 25-hydroxyvitamin d (25(oh)d) concentrations were associated with reduced risk of multiple sclerosis incidence and relapse, non-infectious uveitis and scleritis, psoriasis, femur fracture, leg fracture, amyotrophic lateral sclerosis, anorexia nervosa, delirium, heart failure, ovarian cancer, non-alcoholic fatty liver disease, dyslipidemia, and bacterial pneumonia, but increased risk of behçet's disease, graves' disease, kidney stone disease, fracture of radium/ulna, basal cell carcinoma, and overall cataracts. |
2024-01-12 |
2024-01-14 |
human |
| Jin Gao, Mingchen Jiang, Danilo Erricolo, Richard L Magin, Gerardo Morfini, Thomas Royston, Andrew C Larson, Weiguo L. Identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: Application of the continuous time random walk model to ultrahigh b-value diffusion-weighted MR images of spinal cord tissue. NMR in biomedicine. 2023-09-18. PMID:37721118. |
identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: application of the continuous time random walk model to ultrahigh b-value diffusion-weighted mr images of spinal cord tissue. |
2023-09-18 |
2023-10-07 |
mouse |
| Siying Lin, Haoyang Zhang, Mengling Qi, David N Cooper, Yuedong Yang, Yuanhao Yang, Huiying Zha. Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization. NeuroImage. 2023-08-14. PMID:37579999. |
applications of mendelian randomization (mr) identified significant putative causal effects of multiple region-specific brain idps in relation to the increased risks for amyotrophic lateral sclerosis (als), major depressive disorder (mdd), autism spectrum disorder (asd) and schizophrenia (scz). |
2023-08-14 |
2023-09-07 |
Not clear |
| Olivia Foesleitner, Karl Christian Knop, Matthias Lindenau, Fabian Preisner, Philipp Bäumer, Sabine Heiland, Martin Bendszus, Moritz Kronlag. Quantitative MR Neurography in Multifocal Motor Neuropathy and Amyotrophic Lateral Sclerosis. Diagnostics (Basel, Switzerland). vol 13. issue 7. 2023-04-13. PMID:37046455. |
quantitative mr neurography in multifocal motor neuropathy and amyotrophic lateral sclerosis. |
2023-04-13 |
2023-08-14 |
Not clear |
| Olivia Foesleitner, Karl Christian Knop, Matthias Lindenau, Fabian Preisner, Philipp Bäumer, Sabine Heiland, Martin Bendszus, Moritz Kronlag. Quantitative MR Neurography in Multifocal Motor Neuropathy and Amyotrophic Lateral Sclerosis. Diagnostics (Basel, Switzerland). vol 13. issue 7. 2023-04-13. PMID:37046455. |
the aim of this study was to assess the phenotype of multifocal motor neuropathy (mmn) and amyotrophic lateral sclerosis (als) in quantitative mr neurography. |
2023-04-13 |
2023-08-14 |
Not clear |
| G Milella, A Introna, D M Mezzapesa, E D'Errico, A Fraddosio, M Ucci, S Zoccolella, I L Simon. Clinical Profiles and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis: A Cluster-Based Approach Based on MR Imaging Metrics. AJNR. American journal of neuroradiology. 2023-03-23. PMID:36958798. |
clinical profiles and patterns of neurodegeneration in amyotrophic lateral sclerosis: a cluster-based approach based on mr imaging metrics. |
2023-03-23 |
2023-08-14 |
Not clear |
| Ruizhuo Li, Mengjuan Deng, Yuhong Lin, Wenjing Gao, Bohao Liu, Huimin Xi. Genetically predicted circulating levels of glycine, glutamate, and serotonin in relation to the risks of three major neurodegenerative diseases: A Mendelian randomization analysis. Frontiers in aging neuroscience. vol 14. 2022-09-26. PMID:36158554. |
here, a mendelian randomization (mr) study was conducted to explore whether genetically predicted concentrations of glycine, glutamate and serotonin were associated with risks of alzheimer's disease (ad), parkinson's disease (pd), and amyotrophic lateral sclerosis (als). |
2022-09-26 |
2023-08-14 |
Not clear |
| Tiffany Y S. Editorial Comment: Iron-sensitive MR imaging of the primary motor cortex to differentiate hereditary spastic paraplegia from other motor neuron diseases. European radiology. 2022-09-08. PMID:36074266. |
• conventional and advanced mr techniques may aid in the diagnosis of motor neuron disease.• iron-sensitive mr imaging of the primary motor cortex may reveal changes to help differentiate hereditary spastic paraplegia (hsp) from umm predominant amyotrophic lateral sclerosis (umn-als) and primary lateral sclerosis (pls).• additional research in this area is necessary. |
2022-09-08 |
2023-08-14 |
Not clear |
| M M El Mendili, A-M Grapperon, R Dintrich, J-P Stellmann, J-P Ranjeva, M Guye, A Verschueren, S Attarian, W Zaaraou. Alterations of Microstructure and Sodium Homeostasis in Fast Amyotrophic Lateral Sclerosis Progressors: A Brain DTI and Sodium MRI Study. AJNR. American journal of neuroradiology. 2022-06-30. PMID:35772800. |
while conventional mr imaging has limited value in amyotrophic lateral sclerosis, nonconventional mr imaging has shown alterations of microstructure using diffusion mr imaging and recently sodium homeostasis with sodium mr imaging. |
2022-06-30 |
2023-08-14 |
Not clear |
| Wataru Sako, Yuishin Izumi, Takashi Abe, Shotaro Haji, Nagahisa Murakami, Yusuke Osaki, Yuki Matsumoto, Masafumi Harada, Ryuji Kaj. MR spectroscopy and imaging-derived measurements in the supplementary motor area for biomarkers of amyotrophic lateral sclerosis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 10. 2021-09-17. PMID:33594539. |
mr spectroscopy and imaging-derived measurements in the supplementary motor area for biomarkers of amyotrophic lateral sclerosis. |
2021-09-17 |
2023-08-13 |
Not clear |
| Natalia Cullell, Jara Cárcel-Márquez, Cristina Gallego-Fábrega, Elena Muiño, Laia Llucià-Carol, Miquel Lledós, Karol Enrique Uscamaita Amaut, Jerzy Krupinski, Israel Fernández-Cadena. Sleep/wake cycle alterations as a cause of neurodegenerative diseases: A Mendelian randomization study. Neurobiology of aging. vol 106. 2021-09-14. PMID:34130902. |
our aim was to determine whether there is a causal relationship between sleep and/or wake cycle patterns and nd (parkinson's disease (pd) age at onset (aao), alzheimer's disease (ad), and amyotrophic lateral sclerosis (als)) using two-sample mendelian randomization (mr). |
2021-09-14 |
2023-08-13 |
Not clear |
| Emrah Düzel, Mauro Costagli, Graziella Donatelli, Oliver Speck, Mirco Cosottin. Studying Alzheimer disease, Parkinson disease, and amyotrophic lateral sclerosis with 7-T magnetic resonance. European radiology experimental. vol 5. issue 1. 2021-09-10. PMID:34435242. |
this article reviews the 7 t mr literature reporting the recent studies on the most widespread neurodegenerative diseases: alzheimer's disease, parkinson's disease, and amyotrophic lateral sclerosis. |
2021-09-10 |
2023-08-13 |
Not clear |
| Yixin Gao, Ting Wang, Xinghao Yu, Huashuo Zhao, Ping Zen. Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis. Scientific reports. vol 10. issue 1. 2020-12-14. PMID:32699404. |
we employed mendelian randomization (mr) to evaluate the causal relationship between leukocyte telomere length (ltl) and amyotrophic lateral sclerosis (als) with summary statistics from genome-wide association studies (n = ~ 38,000 for ltl and ~ 81,000 for als in the european population; n = ~ 23,000 for ltl and ~ 4,100 for als in the asian population). |
2020-12-14 |
2023-08-13 |
Not clear |
| Moritz Kronlage, Karl Christian Knop, Daniel Schwarz, Tim Godel, Sabine Heiland, Martin Bendszus, Philipp Bäume. Amyotrophic Lateral Sclerosis versus Multifocal Motor Neuropathy: Utility of MR Neurography. Radiology. vol 292. issue 1. 2020-03-06. PMID:31063079. |
amyotrophic lateral sclerosis versus multifocal motor neuropathy: utility of mr neurography. |
2020-03-06 |
2023-08-13 |
human |