| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mar\\xc3\\xada Andrea Arnanz, Samuel Ruiz de Mart\\xc3\\xadn Esteban, Ana Mar\\xc3\\xada Mart\\xc3\\xadnez Relimpio, Neta Rimmerman, Nurit Tweezer Zaks, Mar\\xc3\\xada Teresa Grande, Juli\\xc3\\xa1n Romer. Effects of Chronic, Low-Dose Cannabinoids, Cannabidiol, Delta-9-Tetrahydrocannabinol and a Combination of Both, on Amyloid Pathology in the 5xFAD Mouse Model of Alzheimer's Disease. Cannabis and cannabinoid research. 2023-10-20. PMID:37862567. |
effects of chronic, low-dose cannabinoids, cannabidiol, delta-9-tetrahydrocannabinol and a combination of both, on amyloid pathology in the 5xfad mouse model of alzheimer's disease. |
2023-10-20 |
2023-11-08 |
mouse |
| Mohammad Hosseininia, Fatemeh Rostami, Ladan Delphi, Zahra Ghasemzadeh, Fatemeh Kouhkan, Ameneh Rezayo. Memory impairment was ameliorated by corticolimbic microinjections of arachidonylcyclopropylamide (ACPA) and miRNA-regulated lentiviral particles in a streptozotocin-induced Alzheimer's rat model. Experimental neurology. 2023-10-02. PMID:37783412. |
the present study aimed to investigate the effect of corticolimbic cannabinoid cb1 receptors activity on memory impairment in the intracerebroventricular (icv)-streptozotocin (stz) animal model of alzheimer's like-disease. |
2023-10-02 |
2023-10-07 |
rat |
| Victor Voicu, Felix-Mircea Brehar, Corneliu Toader, Razvan-Adrian Covache-Busuioc, Antonio Daniel Corlatescu, Andrei Bordeianu, Horia Petre Costin, Bogdan-Gabriel Bratu, Luca-Andrei Glavan, Alexandru Vlad Ciure. Cannabinoids in Medicine: A Multifaceted Exploration of Types, Therapeutic Applications, and Emerging Opportunities in Neurodegenerative Diseases and Cancer Therapy. Biomolecules. vol 13. issue 9. 2023-09-28. PMID:37759788. |
special emphasis is placed on the role of cannabinoids in neurodegenerative diseases, showcasing their potential benefits in conditions such as alzheimer's disease, parkinson's disease, huntington's disease, and multiple sclerosis. |
2023-09-28 |
2023-10-07 |
human |
| Beatriz Pacheco-S\\xc3\\xa1nchez, Rub\\xc3\\xa9n Tovar, Meriem Ben Rabaa, Lourdes S\\xc3\\xa1nchez-Salido, Antonio Vargas, Juan Su\\xc3\\xa1rez, Fernando Rodr\\xc3\\xadguez de Fonseca, Patricia River. Sex-Dependent Altered Expression of Cannabinoid Signaling in Hippocampal Astrocytes of the Triple Transgenic Mouse Model of Alzheimer's Disease: Implications for Controlling Astroglial Activity. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628778. |
sex-dependent altered expression of cannabinoid signaling in hippocampal astrocytes of the triple transgenic mouse model of alzheimer's disease: implications for controlling astroglial activity. |
2023-08-26 |
2023-09-07 |
mouse |
| Carla Fonseca, Miren Ettcheto, Joana Bicker, Maria Jos\\xc3\\xa9 Fernandes, Am\\xc3\\xadlcar Falc\\xc3\\xa3o, Antoni Camins, Ana Fortun. Under the umbrella of depression and Alzheimer's disease physiopathology: can cannabinoids be a dual-pleiotropic therapy? Ageing research reviews. 2023-07-06. PMID:37414155. |
under the umbrella of depression and alzheimer's disease physiopathology: can cannabinoids be a dual-pleiotropic therapy? |
2023-07-06 |
2023-08-14 |
Not clear |
| Dina Medina-Vera, Hongjing Zhao, Erika Bereczki, Cristina Rosell-Valle, Makoto Shimozawa, Gefei Chen, Fernando Rodr\\xc3\\xadguez de Fonseca, Per Nilsson, Simone Tambar. The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer's Disease in Biology. vol 12. issue 6. 2023-06-28. PMID:37372090. |
the expression of the endocannabinoid receptors cb2 and gpr55 is highly increased during the progression of alzheimer's disease in the endocannabinoid system (ecs) and associated lipid transmitter-based signaling systems play an important role in modulating brain neuroinflammation. |
2023-06-28 |
2023-08-14 |
Not clear |
| Juyong Kim, Pilju Choi, Young-Tae Park, Taejung Kim, Jungyeob Ham, Jin-Chul Ki. The Cannabinoids, CBDA and THCA, Rescue Memory Deficits and Reduce Amyloid-Beta and Tau Pathology in an Alzheimer's Disease-like Mouse Model. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047798. |
the cannabinoids, cbda and thca, rescue memory deficits and reduce amyloid-beta and tau pathology in an alzheimer's disease-like mouse model. |
2023-04-13 |
2023-08-14 |
mouse |
| Mohd Amir Kamaruzzaman, Muhammad Hibatullah Romli, Razif Abas, Sharmili Vidyadaran, Mohamad Taufik Hidayat Baharuldin, Muhammad Luqman Nasaruddin, Vishnumukkala Thirupathirao, Sreenivasulu Sura, Kabul Warsito, Nurul Huda Mohd Nor, Muhammad Amsyar Azwaruddin, Mohammed Abdullah Alshawsh, Mohamad Aris Mohd Mokla. Regulatory role of the endocannabinoid system on glial cells toward cognitive function in Alzheimer's disease: A systematic review and meta-analysis of animal studies. Frontiers in pharmacology. vol 14. 2023-03-24. PMID:36959856. |
regulatory role of the endocannabinoid system on glial cells toward cognitive function in alzheimer's disease: a systematic review and meta-analysis of animal studies. |
2023-03-24 |
2023-08-14 |
Not clear |
| Marzie Khavandi, Praveen P N Rao, Michael A Beazel. Differential Effects of Endocannabinoids on Amyloid-Beta Aggregation and Toxicity. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674424. |
the regulation and metabolism of the endocannabinoid system has received extensive attention for their potential neuroprotective effect in neurodegenerative diseases such as alzheimer's disease (ad), which is characterized by amyloid \xce\xb2 (a\xce\xb2) -induced cell toxicity, inflammation, and oxidative stress. |
2023-01-21 |
2023-08-14 |
mouse |
| Alana C Costa, Helena P G Joaquim, Jo\\xc3\\xa3o F C Pedrazzi, Andreia de O Pain, Gustavo Duque, Ivan Aprahamia. Cannabinoids in Late Life Parkinson's Disease and Dementia: Biological Pathways and Clinical Challenges. Brain sciences. vol 12. issue 12. 2022-12-23. PMID:36552056. |
these findings suggest a potential therapeutic role of cannabinoids to neurodegenerative disorders such as parkinson's disease (pd) and alzheimer. |
2022-12-23 |
2023-08-14 |
Not clear |
| Alana C Costa, Helena P G Joaquim, Jo\\xc3\\xa3o F C Pedrazzi, Andreia de O Pain, Gustavo Duque, Ivan Aprahamia. Cannabinoids in Late Life Parkinson's Disease and Dementia: Biological Pathways and Clinical Challenges. Brain sciences. vol 12. issue 12. 2022-12-23. PMID:36552056. |
some clinicians consider cannabinoids an alternative for older adults bearing parkinson's disease and alzheimer's dementia with a poor response to first-line treatments. |
2022-12-23 |
2023-08-14 |
Not clear |
| Henry Blanton, P Hemachandra Reddy, Khalid Benama. Chronic pain in Alzheimer's disease: Endocannabinoid system. Experimental neurology. 2022-12-01. PMID:36455638. |
chronic pain in alzheimer's disease: endocannabinoid system. |
2022-12-01 |
2023-08-14 |
Not clear |
| Eduarda Dal Pisol Schwab, Ruliam Queiroz, Anne Karine Bosetto Fiebrantz, Murilo Bastos, Juliana Sartori Bonini, Weber Cl\\xc3\\xa1udio Francisco Nunes da Silv. Hypothesis on ontogenesis and pathophysiology of Alzheimer's disease. Einstein (Sao Paulo, Brazil). vol 20. 2022-11-30. PMID:36449761. |
some factors, such as excitotoxicity, cholinergic dysfunctions, oxidative stress, tau protein hyperphosphorylation, changes in amyloid-beta peptide metabolism, herpes viruses, apolipoprotein e, glycogen synthase kinase 3, insulin resistance, and the endocannabinoid system seem to be related to pathophysiology of alzheimer's disease. |
2022-11-30 |
2023-08-14 |
Not clear |
| Itziar Terradillos, Itziar Bonilla-Del R\\xc3\\xado, Nagore Puente, Maitane Serrano, Amaia Mimenza, Leire Lekunberri, Ilazki Anaut-Lusar, Leire Reguero, Inmaculada Gerrikagoitia, Samuel Ruiz de Mart\\xc3\\xadn Esteban, Cecilia J Hillard, Mar\\xc3\\xada T Grande, Juli\\xc3\\xa1n Romero, Izaskun Elezgarai, Pedro Grande. Altered glial expression of the cannabinoid 1 receptor in the subiculum of a mouse model of Alzheimer's disease. Glia. 2022-11-28. PMID:36437738. |
altered glial expression of the cannabinoid 1 receptor in the subiculum of a mouse model of alzheimer's disease. |
2022-11-28 |
2023-08-14 |
mouse |
| P\\xc3\\xa2mela C L Ferreira, Bruna Bellaver, Guilherme Povala, Wagner S Brum, C\\xc3\\xa9cile Tissot, Atef Badji, Matthew E Sloan, Andr\\xc3\\xa9a L Benedet, Pedro Rosa-Neto, Nicholas J Ashton, Tharick A Pascoal, Antoine Leuzy, Eduardo R Zimme. Endocannabinoid System Biomarkers in Alzheimer's Disease. Cannabis and cannabinoid research. 2022-11-17. PMID:36394442. |
endocannabinoid system biomarkers in alzheimer's disease. |
2022-11-17 |
2023-08-14 |
Not clear |
| Vasil Kecheliev, Francesco Spinelli, Adrienne Herde, Ahmed Haider, Linjing Mu, Jan Klohs, Simon M Ametamey, Ruiqing N. Evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of Alzheimer's disease. Frontiers in aging neuroscience. vol 14. 2022-10-17. PMID:36248003. |
evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of alzheimer's disease. |
2022-10-17 |
2023-08-14 |
mouse |
| Alberto Llorente-Ovejero, Iker Bengoetxea de Tena, Jonatan Mart\\xc3\\xadnez-Gardeazabal, Marta Moreno-Rodr\\xc3\\xadguez, Laura Lombardero, Iv\\xc3\\xa1n Manuel, Rafael Rodr\\xc3\\xadguez-Puerta. Cannabinoid Receptors and Glial Response Following a Basal Forebrain Cholinergic Lesion. ACS pharmacology & translational science. vol 5. issue 9. 2022-09-16. PMID:36110372. |
the endocannabinoid system modulates learning, memory, and neuroinflammatory processes, playing a key role in neurodegeneration, including alzheimer's disease (ad). |
2022-09-16 |
2023-08-14 |
rat |
| Ana Carolina Ruver-Martins, Ma\\xc3\\xadra Assun\\xc3\\xa7\\xc3\\xa3o Bicca, Fabiano Soares de Araujo, Beatriz Helena Lameiro de Noronha Sales Maia, Fabr\\xc3\\xadcio Alano Pamplona, Elton Gomes da Silva, Francisney Pinto Nasciment. Cannabinoid extract in microdoses ameliorates mnemonic and nonmnemonic Alzheimer's disease symptoms: a case report. Journal of medical case reports. vol 16. issue 1. 2022-07-12. PMID:35820856. |
cannabinoid extract in microdoses ameliorates mnemonic and nonmnemonic alzheimer's disease symptoms: a case report. |
2022-07-12 |
2023-08-14 |
Not clear |
| Yolanda Paes-Colli, Andrey F L Aguiar, Alinny Rosendo Isaac, Bruna K Ferreira, Raquel Maria P Campos, Priscila Martins Pinheiro Trindade, Ricardo Augusto de Melo Reis, Luzia S Sampai. Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice. Frontiers in cellular neuroscience. vol 16. 2022-06-16. PMID:35707521. |
in clinical practice, cannabis products have already been introduced to treatment regimens of alzheimer's disease, parkinson's disease and multiple sclerosis's patients, and the mechanisms of action behind the reported improvement in the clinical outcome and disease progression are associated with their anti-inflammatory, immunosuppressive, antioxidant, and neuroprotective properties, due to the modulation of the endocannabinoid system. |
2022-06-16 |
2023-08-14 |
Not clear |
| Yolanda Paes-Colli, Andrey F L Aguiar, Alinny Rosendo Isaac, Bruna K Ferreira, Raquel Maria P Campos, Priscila Martins Pinheiro Trindade, Ricardo Augusto de Melo Reis, Luzia S Sampai. Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice. Frontiers in cellular neuroscience. vol 16. 2022-06-16. PMID:35707521. |
in this review, we describe the role played by the endocannabinoid system in the physiopathology of alzheimer, parkinson, and multiple sclerosis, mainly at the neuroimmunological level. |
2022-06-16 |
2023-08-14 |
Not clear |