| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Na Gao, Hantao Chen, Xutao Guo, Xingyu Hao, Ting M. Geodesic shape regression based deep learning segmentation for assessing longitudinal hippocampal atrophy in dementia progression. NeuroImage. Clinical. vol 43. 2024-05-31. PMID:38821013. |
when assessing hippocampal atrophy in longitudinal data from the alzheimer's disease neuroimaging initiative (adni), results based on geolongseg exhibit spatial and temporal local atrophy in bilateral hippocampi of dementia patients. |
2024-05-31 |
2024-06-02 |
Not clear |
| Rong Ye, Anna E Goodheart, Joseph J Locascio, Erin Peterec, Michael Properzi, Emma G Thibault, Erin Chuba, Keith A Johnson, Michael J Brickhouse, Alexandra Touroutoglou, John H Growdon, Bradford C Dickerson, Stephen N Gompert. Differential Vulnerability of Hippocampal Subfields to Amyloid and Tau Deposition in the Lewy Body Diseases. Neurology. vol 102. issue 12. 2024-05-30. PMID:38815233. |
alzheimer disease (ad) copathologies of β-amyloid and tau are common in the lewy body diseases (lbd), dementia with lewy bodies (dlb) and parkinson disease (pd), and target distinct hippocampal subfields compared with lewy pathology, including subiculum and ca1. |
2024-05-30 |
2024-07-16 |
Not clear |
| Asal Safarbalou, Norah Khaled Algarzae, Musaad Bedah Alsahly, Thamer Abdullah Alsufayan, Humidah Alanazi, Adeel Abbas. Oral administration of liposome-encapsulated thymol could alleviate the inflammatory parameters in serum and hippocampus in a rat model of Alzheimer's disease. Experimental gerontology. 2024-05-27. PMID:38801839. |
oral administration of liposome-encapsulated thymol could alleviate the inflammatory parameters in serum and hippocampus in a rat model of alzheimer's disease. |
2024-05-27 |
2024-06-01 |
rat |
| Jr-Jiun Liou, Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh, Nadim Farhat, Minjie Wu, Howard Aizenstein, Joseph M Mettenburg, William Yong, Elizabeth Head, Milos Ikonomovic, Tamer Ibrahim, Julia Kofle. Correlating hippocampal and amygdala volumes with neuropathological burden in neurodegenerative diseases using 7T postmortem MRI. medRxiv : the preprint server for health sciences. 2024-05-27. PMID:38798514. |
using 7t postmortem ex vivo mri, we explore the potential correlation of amygdala and hippocampal atrophy with neuropathological burden in both down syndrome (ds) and alzheimer's disease (ad) cohorts. |
2024-05-27 |
2024-05-31 |
human |
| b' Kinga Igloi, Blanca Marin Bosch, No\xe9mie Kuenzi, Aur\xe9lien Thomas, Estelle Lauer, Aur\xe9lien Bringard, Sophie Schwart. Interactions between physical exercise, associative memory, and genetic risk for Alzheimer\'s disease. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 5. 2024-05-27. PMID:38802684.' |
interactions between physical exercise, associative memory, and genetic risk for alzheimer's disease. |
2024-05-27 |
2024-06-03 |
human |
| Miriam Aceves, Jose Granados, Ana C Leandro, Juan Peralta, David C Glahn, Sarah Williams-Blangero, Joanne E Curran, John Blangero, Satish Kuma. Role of Neurocellular Endoplasmic Reticulum Stress Response in Alzheimer's Disease and Related Dementias Risk. Genes. vol 15. issue 5. 2024-05-25. PMID:38790197. |
the spread of alzheimer's disease (ad) pathology and progressive neurodegeneration in the hippocampus and cerebral cortex is strongly correlated with cognitive decline in ad patients; however, the molecular underpinning of adrd's causality is still unclear. |
2024-05-25 |
2024-05-27 |
Not clear |
| Isabel Paiva, Jonathan Seguin, Iris Grgurina, Akash Kumar Singh, Brigitte Cosquer, Damien Plassard, Laura Tzeplaeff, Stephanie Le Gras, Ludovica Cotellessa, Charles Decraene, Johanne Gambi, Rafael Alcala-Vida, Muthusamy Eswaramoorthy, Luc Buée, Jean-Christophe Cassel, Paolo Giacobini, David Blum, Karine Merienne, Tapas K Kundu, Anne-Laurence Boutillie. Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons. Neurobiology of disease. 2024-05-24. PMID:38789057. |
dysregulated expression of cholesterol biosynthetic genes in alzheimer's disease alters epigenomic signatures of hippocampal neurons. |
2024-05-24 |
2024-05-27 |
mouse |
| Meher Lad, John-Paul Taylor, Tim D Griffith. Subjective hearing loss is not associated with an increased risk of Alzheimer's disease dementia. Heliyon. vol 10. issue 9. 2024-05-21. PMID:38765087. |
we assessed cognitively normal and mild cognitively impaired participants from the alzheimer's disease neuroimaging initiative with subjective hearing loss to examine if they had faster decline in episodic memory scores, hippocampal volume and greater ptau positivity. |
2024-05-21 |
2024-05-27 |
human |
| Hassan Fazelinejad, Elham Zahedi, Mehdi Khadiv. Altering plasma lipids and liver enzyme activities via hippocampal injections of hen Lysozyme amyloid aggregates in an Alzheimer's disease mouse model: Insights into the therapeutic role of Bis (Indolyl) phenylmethane. Neuroscience letters. 2024-05-20. PMID:38768939. |
altering plasma lipids and liver enzyme activities via hippocampal injections of hen lysozyme amyloid aggregates in an alzheimer's disease mouse model: insights into the therapeutic role of bis (indolyl) phenylmethane. |
2024-05-20 |
2024-05-27 |
mouse |
| Hamid Shokati Basir, Naser Mirazi, Alireza Komaki, Abdolkarim Hossein. Cacao consumption improves passive avoidance memory impairment in a rat model of Alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress. Frontiers in pharmacology. vol 15. 2024-05-18. PMID:38756381. |
cacao consumption improves passive avoidance memory impairment in a rat model of alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress. |
2024-05-18 |
2024-05-27 |
rat |
| Ling Xiao Yi, Li Zeng, Qing Wang, Eng King Tan, Zhi Dong Zho. Reelin links Apolipoprotein E4, Tau, and Amyloid-β in Alzheimer's disease. Ageing research reviews. vol 98. 2024-05-17. PMID:38754634. |
alzheimer's disease (ad) is the most common neurodegenerative disorder that affects the cerebral cortex and hippocampus, and is characterised by progressive cognitive decline and memory loss. |
2024-05-17 |
2024-05-27 |
mouse |
| Andrea Du Preez, Sophie Lefèvre-Arbogast, Raúl González-Domínguez, Vikki Houghton, Chiara de Lucia, Hyunah Lee, Dorrain Y Low, Catherine Helmer, Catherine Féart, Cécile Delcourt, Cécile Proust-Lima, Mercè Pallàs, Alex Sánchez-Pla, Mireia Urpi-Sardà, Silvie R Ruigrok, Barbara Altendorfer, Ludwig Aigner, Paul J Lucassen, Aniko Korosi, Claudine Manach, Cristina Andres-Lacueva, Cécilia Samieri, Sandrine Thure. Association of dietary and nutritional factors with cognitive decline, dementia, and depressive symptomatology in older individuals according to a neurogenesis-centred biological susceptibility to brain ageing. Age and ageing. vol 53. issue Supplement_2. 2024-05-15. PMID:38745492. |
using a subsample (n = 371) of the three-city cohort-where older adults provided information on diet and blood biobanking at baseline and were assessed for cd, dementia, and depressive symptomatology across 12 years-we tested for interactions between food consumption, nutrient intake, and nutritional biomarker concentrations and neurogenesis-centred susceptibility status (defined by baseline readouts of hippocampal progenitor cell integrity, cell death, and differentiation) on cd, alzheimer's disease (ad), vascular and other dementias (vod), and depressive symptomatology, using multivariable-adjusted logistic regression models. |
2024-05-15 |
2024-05-27 |
Not clear |
| Robert S Hurley, Brittany Lapin, Stephen E Jones, Anna Crawford, James B Leverenz, Aaron Bonner-Jackson, Jagan A Pilla. Hemispheric asymmetries in hippocampal volume related to memory in left and right temporal variants of frontotemporal degeneration. Frontiers in neurology. vol 15. 2024-05-14. PMID:38742046. |
in addition to alzheimer's disease (ad), the hippocampus is now known to be affected in variants of frontotemporal degeneration (ftd). |
2024-05-14 |
2024-05-27 |
human |
| Yan Wu, Jinhao Cheng, Jie Qi, Chen Hang, Ruihua Dong, Boon Chuan Low, Hanry Yu, Xingyu Jian. Three-dimensional liquid metal-based neuro-interfaces for human hippocampal organoids. Nature communications. vol 15. issue 1. 2024-05-14. PMID:38744873. |
human hippocampal organoids (hhos) derived from human induced pluripotent stem cells (hipscs) have emerged as promising models for investigating neurodegenerative disorders, such as schizophrenia and alzheimer's disease. |
2024-05-14 |
2024-05-27 |
human |
| Mattia Bonzanni, Alice Braga, Takashi Saito, Takaomi C Saido, Giuseppina Tesco, Philip G Haydo. Adenosine deficiency facilitates CA1 synaptic hyperexcitability in the presymptomatic phase of a knock in mouse model of Alzheimer's disease. bioRxiv : the preprint server for biology. 2024-05-13. PMID:38712028. |
the disease's trajectory of alzheimer's disease (ad) is associated with and worsened by hippocampal hyperexcitability. |
2024-05-13 |
2024-05-27 |
mouse |
| Chunlan Zhang, Ruxin Tan, Xiaoqing Zhou, Ruru Wang, Xin Wang, Ren Ma, Fangxuan Chu, Ying Li, Tao Yin, Zhipeng Li. Transcranial Magneto-Acoustic Stimulation Protects Synaptic Rehabilitation from Amyloid-Beta Plaques via Regulation of Microglial Functions. International journal of molecular sciences. vol 25. issue 9. 2024-05-11. PMID:38731870. |
overall, our study highlights that stimulation of hippocampal microglia by tmas treatment can induce anti-cognitive impairment effects via pi3k-akt signaling, providing hope for the development of new strategies for an adjuvant therapy for alzheimer's disease. |
2024-05-11 |
2024-05-27 |
mouse |
| Samar R Saleh, Aml Abd-Elmegied, Somaya Aly Madhy, Sherine N Khattab, Eman Sheta, Fatma Y Elnozahy, Radwa A Mehanna, Doaa A Ghareeb, Nihad M Abd-Elmone. Brain-targeted Tet-1 peptide-PLGA nanoparticles for berberine delivery against STZ-induced Alzheimer's disease in a rat model: Alleviation of hippocampal synaptic dysfunction, Tau pathology and amyloidogenesis. International journal of pharmaceutics. 2024-05-11. PMID:38734273. |
brain-targeted tet-1 peptide-plga nanoparticles for berberine delivery against stz-induced alzheimer's disease in a rat model: alleviation of hippocampal synaptic dysfunction, tau pathology and amyloidogenesis. |
2024-05-11 |
2024-05-27 |
rat |
| Nabeela Yaqoob, Muhammad Attique Khan, Saleha Masood, Hussain Mobarak Albarakati, Ameer Hamza, Fatimah Alhayan, Leila Jamel, Anum Masoo. Prediction of Alzheimer's disease stages based on ResNet-Self-attention architecture with Bayesian optimization and best features selection. Frontiers in computational neuroscience. vol 18. 2024-05-10. PMID:38725868. |
alzheimer's disease (ad) is a neurodegenerative illness that impairs cognition, function, and behavior by causing irreversible damage to multiple brain areas, including the hippocampus. |
2024-05-10 |
2024-05-27 |
Not clear |
| Deepthi Rapaka, Motshegwana O Tebogo, Elizabeth M Mathew, Paul C Adiukwu, Veera Raghavulu Bitr. Targeting papez circuit for cognitive dysfunction- insights into deep brain stimulation for Alzheimer's disease. Heliyon. vol 10. issue 9. 2024-05-10. PMID:38726200. |
hippocampus is the most widely studied brain area coupled with impairment of memory in a variety of neurological diseases and alzheimer's disease (ad). |
2024-05-10 |
2024-05-27 |
Not clear |
| Hsi-Chun Wang, Chia-Sho Chen, Chung-Chin Kuo, Teng-Yi Huang, Kuei-Hong Kuo, Tzu-Chao Chuang, Yi-Ru Lin, Hsiao-Wen Chun. Comparative assessment of established and deep learning-based segmentation methods for hippocampal volume estimation in brain magnetic resonance imaging analysis. NMR in biomedicine. 2024-05-07. PMID:38712667. |
in terms of alzheimer's disease classification based on the hippocampal atrophy rate, synthseg and tigerbx exhibited superior performance. |
2024-05-07 |
2024-05-27 |
Not clear |