| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Celeste Parra Bravo, Sarah A Naguib, Li Ga. Cellular and pathological functions of tau. Nature reviews. Molecular cell biology. 2024-07-16. PMID:39014245. |
tauopathies are neurodegenerative diseases marked by the abnormal accumulation of tau protein aggregates in neurons, as seen, for example, in conditions such as frontotemporal dementia and alzheimer disease. |
2024-07-16 |
2024-07-19 |
human |
| Büşra Yurt Turer, Nevin Sanlie. Relationship of Curcumin with Aging and Alzheimer and Parkinson Disease, the Most Prevalent Age-Related Neurodegenerative Diseases: A Narrative Review. Nutrition reviews. 2024-06-25. PMID:38916925. |
relationship of curcumin with aging and alzheimer and parkinson disease, the most prevalent age-related neurodegenerative diseases: a narrative review. |
2024-06-25 |
2024-06-27 |
Not clear |
| Alexis Heng Boon Chin, Nimah Alsomali, Sayyed Mohamed Muhsi. Should brain chip implants for memory and cognitive enhancement be banned in competitive national examinations? Neurosurgical review. vol 47. issue 1. 2024-05-25. PMID:38795179. |
while certainly representing a significant medical milestone for many patients afflicted with debilitating brain and spinal cord injuries, as well as devastating neurodegenerative diseases such as parkinson's and alzheimer's, it must be noted that this very same technology can also be manipulated for human memory or cognitive enhancement. |
2024-05-25 |
2024-05-27 |
human |
| Zihao Li, Ye Zhang, Meiling Ji, Chenglong Wu, Yanxing Zhang, Senlin J. Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 176. 2024-05-25. PMID:38795640. |
neurodegenerative diseases result from neuronal degeneration or demyelination in the brain or spinal cord, such as alzheimer's disease, parkinson's disease, huntington's disease, and amyotrophic lateral sclerosis. |
2024-05-25 |
2024-05-31 |
Not clear |
| Anne Rombaut, Danica Jovancevic, Raymond Ching-Bong Wong, Alan Nicol, Rune Brautaset, David I Finkelstein, Christine T O Nguyen, James R Tribble, Pete A William. Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection. Acta neuropathologica communications. vol 12. issue 1. 2024-05-22. PMID:38773545. |
the retina is often affected in common neurodegenerative diseases such as parkinson's and alzheimer's disease. |
2024-05-22 |
2024-05-27 |
mouse |
| Erica Costantini, Claudia Carrarini, Dario Calisi, Matteo De Rosa, Marianna Simone, Adolfo Di Crosta, Rocco Palumbo, Alessia Cipollone, Lisa Aielli, Maria De Laurentis, Lucilla Colarusso, Andrea Pilotto, Alessandro Padovani, Fani Konstantinidou, Valentina Gatta, Liborio Stuppia, Francesco Cipollone, Marta Di Nicola, Marcella Reale, Laura Bonann. Search in the Periphery for Potential Inflammatory Biomarkers of Dementia with Lewy Bodies and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-05-17. PMID:38759010. |
neuroinflammation, with altered peripheral proinflammatory cytokine production, plays a major role in the pathogenesis of neurodegenerative diseases, such as alzheimer's disease (ad), while the role of inflammation in dementia with lewy bodies (dlb) is less known and the results of different studies are often in disagreement. |
2024-05-17 |
2024-05-27 |
Not clear |
| C Y Chen, Y H Tseng, J P War. A mathematical model on the propagation of tau pathology in neurodegenerative diseases. Journal of mathematical biology. vol 89. issue 1. 2024-05-15. PMID:38750128. |
a system of partial differential equations is developed to study the spreading of tau pathology in the brain for alzheimer's and other neurodegenerative diseases. |
2024-05-15 |
2024-05-27 |
Not clear |
| Mohit Kumar, Sharma Anita Ashok, Ashok Kumar Datusalia, Gopal L Khati. PPARs (Peroxisome Proliferator-activated Receptors) and Their Agonists in Alzheimer's Disease. Medicinal chemistry (Shariqah (United Arab Emirates)). 2024-05-10. PMID:38726789. |
alzheimer's disease (ad) is a neurodegenerative disease leading to dementia because of complex phathomechanisms like amyloid β (aβ) aggregation, tau aggregates, and neurofibrillary tangles. |
2024-05-10 |
2024-05-27 |
human |
| Yan Gao, Yaoping Lu, Xiaojing Liang, Mengwei Zhao, Xinyue Yu, Haiying Fu, Wei Yan. CD4 Cells. vol 13. issue 9. 2024-05-10. PMID:38727285. |
neurodegenerative diseases (nds), including multiple sclerosis (ms), alzheimer's disease (ad), parkinson's disease (pd), and amyotrophic lateral sclerosis (als), are characterized by progressive neurodegeneration associated with aging, leading to a gradual decline in cognitive, emotional, and motor functions in patients. |
2024-05-10 |
2024-05-27 |
human |
| Alexandra M R McLaren, Michael D Kawaj. Olfactory Dysfunction and Alzheimer's Disease: A Review. Journal of Alzheimer's disease : JAD. 2024-05-10. PMID:38728185. |
a substantial body of evidence has emerged demonstrating that olfactory dysfunction is a preclinical symptom of neurodegenerative diseases including alzheimer's disease. |
2024-05-10 |
2024-05-27 |
Not clear |
| Grigorii Sultanakhmetov, Sophia Jobien M Limlingan, Aoi Fukuchi, Keisuke Tsuda, Hirokazu Suzuki, Iori Kato, Taro Saito, Adam Z Weitemier, Kanae And. Brain communications. vol 6. issue 3. 2024-05-08. PMID:38712317. |
accumulation of abnormally phosphorylated tau proteins is linked to various neurodegenerative diseases, including alzheimer's disease and frontotemporal dementia. |
2024-05-08 |
2024-05-27 |
Not clear |
| Fatemeh Seifar, Edward J Fox, Anantharaman Shantaraman, Yue Liu, Eric B Dammer, Erica Modeste, Duc M Duong, Luming Yin, Adam N Trautwig, Qi Guo, Kaiming Xu, Lingyan Ping, Joseph S Reddy, Mariet Allen, Zachary Quicksall, Laura Heath, Jo Scanlan, Erming Wang, Minghui Wang, Abby Vander Linden, William Poehlman, Xianfeng Chen, Saurabh Baheti, Charlotte Ho, Thuy Nguyen, Geovanna Yepez, Adriana O Mitchell, Stephanie R Oatman, Xue Wang, Minerva M Carrasquillo, Alexi Runnels, Thomas Beach, Geidy E Serrano, Dennis W Dickson, Edward B Lee, Todd E Golde, Stefan Prokop, Lisa L Barnes, Bin Zhang, Varham Haroutunian, Marla Gearing, James J Lah, Philip De Jager, David A Bennett, Anna Greenwood, Nilüfer Ertekin-Taner, Allan I Levey, Aliza Wingo, Thomas Wingo, Nicholas T Seyfrie. Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity. bioRxiv : the preprint server for biology. 2024-05-07. PMID:38712030. |
alzheimer's disease (ad) is the most prevalent neurodegenerative disease, yet our comprehension predominantly relies on studies within the non-hispanic white (nhw) population. |
2024-05-07 |
2024-05-27 |
Not clear |
| Mansour Haidar, Benjamin Schmid, Agustín Ruiz, Andreas Ebneth, Alfredo Cabrera-Socorr. Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch. Stem cell research. vol 77. 2024-05-04. PMID:38703665. |
late-onset alzheimer's disease (ad) has become the paradigm of a non-mendelian complex neurodegenerative disease, for which a major genetic determinant is known, the apoe locus. |
2024-05-04 |
2024-05-07 |
Not clear |
| Dylan J Finneran, Taylor Desjarlais, Alayna Henry, Brianna M Jackman, Marcia N Gordon, David Morga. Induction of tauopathy in a mouse model of amyloidosis using intravenous administration of adeno-associated virus vectors expressing human P301L tau. Alzheimer's & dementia (New York, N. Y.). vol 10. issue 2. 2024-05-01. PMID:38689599. |
alzheimer's disease (ad) is a progressive neurodegenerative disease in which extracellular aggregates of the amyloid beta (aβ) peptide precede widespread intracellular inclusions of the microtubule-associated protein tau. |
2024-05-01 |
2024-05-03 |
mouse |
| Hyun-Ju Lee, JinHan Nam, Jeong-Woo Hwang, Jin-Hee Park, Yoo Joo Jeong, Ji-Yeong Jang, Su-Jeong Kim, A-Ran Jo, Hyang-Sook Ho. L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD. Molecular brain. vol 17. issue 1. 2024-04-30. PMID:38685105. |
dopamine plays important roles in cognitive function and inflammation and therefore is involved in the pathogenesis of neurodegenerative diseases, including alzheimer's disease (ad). |
2024-04-30 |
2024-05-03 |
mouse |
| Anastasiia Nefodova, Mariia Rudyk, Roman Dovhyi, Taisa Dovbynchuk, Nataliia Dzubenko, Ganna Tolstanova, Larysa Skivk. Systemic inflammation in Aβ Brain research. 2024-04-28. PMID:38679313. |
systemic inflammation in aβ alzheimer disease (ad) is the most frequent cause of dementia, and the most common neurodegenerative disease, which is characterized by memory impairment, neuronal death, and synaptic loss in the hippocampus. |
2024-04-28 |
2024-05-01 |
rat |
| Allwin Ebenezer Sahayaraj, Arshad Abdul Vahid, Asmita Dhara, Ann Teres Babu, Vinesh Vijaya. Role of G326 in Determining the Aggregation Propensity of R3 Tau Repeat: Insights from Studies on R1R3 Tau Construct. The journal of physical chemistry. B. 2024-04-27. PMID:38676652. |
the microtubule-binding repeat region (mtbr) of tau has been studied extensively due to its pathological implications in neurodegenerative diseases like alzheimer's disease. |
2024-04-27 |
2024-04-30 |
Not clear |
| Sachin P Patil, Bella R Kueh. Discovery of Small Molecule Glycolytic Stimulants for Enhanced ApoE Lipidation in Alzheimer's Disease Cell Model. Pharmaceuticals (Basel, Switzerland). vol 17. issue 4. 2024-04-27. PMID:38675451. |
alzheimer's disease (ad) is a progressive neurodegenerative disease characterized by pathophysiological deposits of extracellular amyloid beta (aβ) peptides and intracellular neurofibrillary tangles of tau. |
2024-04-27 |
2024-04-29 |
human |
| Faisal A Alzahrani, Yasir M Riza, Thamir M Eid, Reema Almotairi, Lea Scherschinski, Jessica Contreras, Muhammed Nadeem, Sylvia E Perez, Sudhanshu P Raikwar, Ruchira M Jha, Mark C Preul, Andrew F Ducruet, Michael T Lawton, Kanchan Bhatia, Naseem Akhter, Saif Ahma. Exosomes in Vascular/Neurological Disorders and the Road Ahead. Cells. vol 13. issue 8. 2024-04-26. PMID:38667285. |
neurodegenerative diseases, such as alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), huntington's disease (hd), stroke, and aneurysms, are characterized by the abnormal accumulation and aggregation of disease-causing proteins in the brain and spinal cord. |
2024-04-26 |
2024-04-28 |
Not clear |
| Ethan D Smith, Robert McKenna, Mario Mietzsch, David R Borchelt, Stefan Prokop, Paramita Chakrabart. Hyperacetylation mimetics within the tau filament core inhibits prion-like propagation of misfolded tau. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38659970. |
acetylation of key lysine residues characterizes aggregates of the microtubule-associated protein tau constituting the neuropathological hallmark of many neurodegenerative diseases, such as alzheimer's disease (ad) and progressive supranuclear palsy (psp). |
2024-04-25 |
2024-04-28 |
Not clear |